3992 completed, 1296 unknown, 863 recruiting, 407 terminated. 3047 Not applicable, 1241 Phase 2, 846 Phase 3, 499 Phase 1, 429 Phase 4.
Follow Otorhinolaryngologic Diseases: new trials by email Literature Review of Otorhinolaryngologic Diseases trials Research Report on Otorhinolaryngologic Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Acoustic Resonance Therapy for Treating Empty Nose Syndrome Personalized ART, Non-personalized ART - Empty Nose Syndrome, Nasal Obstruction | Not applicable | Not yet recruiting | Stanford University | 40 | 2028-07-01 | 2025-10-10 |
| EFFECT OF AYURVEDA TREATMENT IN ALLERGIC RHINITIS AYURVEDA treatment protocol, Control(Citrizine 10mg) - Allergic Rhinitis (AR) | Not applicable | Not yet recruiting | Amrita Vishwa Vidyapeetham | 104 | 2028-06-30 | 2026-06-04 |
| AI-Enabled Mobile App for Safe Eating in Older Adults With Dysphagia AI-Enabled Mobile Application plus Standard Care, Standard Dysphagia Education - Deglutition Disorders, Dysphagia | Not applicable | Not yet recruiting | KAM Chi Shan Anna | 332 | 2028-01-01 | 2026-09-23 |
| Role of Exposure in Hyperacusis Psychoeducation - Hyperacusis | Not applicable | Not yet recruiting | University Hospital, Antwerp | 5 | 2027-12-07 | 2026-04-29 |
| A Personalized Voice Restoration Device for Patients With Laryngectomy Surface Electromyography - Dysphonia, Aphonia | Not applicable | Not yet recruiting | Weill Medical College of Cornell University | 100 | 2027-12-01 | 2026-06-16 |
| First In Human Randomised Trial of Rincell-1 in Adults With a Cochlear Implant Otic neural progenitors, cochlear implantation - Sensorineural Hearing Loss, Presbyacusis | Phase 1 / Phase 2 | Not yet recruiting | Rinri Therapeutics | 20 | 2027-09-01 | 2026-10-01 |
| Hearing Loss and Brain Health Study Over-The-Counter (OTC) hearing aid - Hearing Loss, Adult-Onset, Dementia | Not applicable | Not yet recruiting | University of Southern California | 40 | 2027-07-01 | 2026-05-08 |
| Optimizing Dysphagia Treatment Delivery in Acute Care: A Hybrid Efficacy Implementation Trial Expiratory muscle strength training (EMST), Standard of Care Dysphagia Treatment, Intensive Dysphagia Treatment - Dysphagia, Critical Illness | Not applicable | Not yet recruiting | Vanderbilt University Medical Center | 120 | 2027-07-01 | 2026-10-14 |
| Parent Implemented Oral Nutrition, Eating, and Esophageal Reflexes Reintegration Protocol: RCT PIONEER Protocol - Deglutition Disorders in Infants, Chronic Tube Feeding in Hospitalized Infants | Not applicable | Not yet recruiting | Nationwide Children's Hospital | 130 | 2027-07-01 | 2026-08-28 |
| Microtable® Method for Cochlear Implantation Investigational Device Exemption (IDE) The Microtable® Stereotactic System - Hearing Loss, Cochlear | Not applicable | Not yet recruiting | Medical University of South Carolina | 12 | 2027-07-01 | 2026-06-18 |
| Cochlear Implantation and Social Outcomes Cochlear implant - Hearing Loss, Bilateral Sensorineural | Not yet recruiting | University of Southern California | 40 | 2027-07-01 | 2026-06-22 | |
| Intervention for Hearing Health Among Native Americans Talking Circle, Diabetes prevention program & delayed TC - Noise-Induced Hearing Loss | Not applicable | Not yet recruiting | University of California, San Francisco | 400 | 2027-04-01 | 2026-08-21 |
| Swallowing Impairments in ICU Survivors and Community-Dwelling Adults Dysphagia, Healthy Aging | Withdrawn | Vanderbilt University Medical Center | 2027-04-01 | 2026-06-02 | ||
| Maximizing Quality of Life After Cancer Through Rehabilitation TIMELY REHAB - Head and Neck Cancer, Hearing Loss | Not applicable | Not yet recruiting | VA Office of Research and Development | 74 | 2027-03-01 | 2026-06-03 |
| From Early Music Audiometry to Tone Audiograms Soundfield Behavioral Audiometry - Hearing Loss, Audiometric Tests | Not yet recruiting | Guy's and St Thomas' NHS Foundation Trust | 100 | 2027-03-01 | 2026-07-24 | |
| A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus) Glycerol Tributyrate - MELAS Syndrome, Lebers Hereditory Optic Neuropathy With Extra Ocular Symptoms (LHON-Plus) | Phase 1 / Phase 2 | Not yet recruiting | George Washington University | 24 | 2027-03-01 | 2026-10-05 |
| Proactively Intervening On Early Cranial Nerve Injury As A Delayed Sequela Of Oropharyngeal Cancer: A Randomized Feasibility Clinical Trial For Pro-Habilitation (proNERVE RCT) Prednisone, Ajovy, Manual Therapy - Cranial Nerve Injury, Oropharyngeal Cancer | Phase 1 | Not yet recruiting | M.D. Anderson Cancer Center | 48 | 2027-03-01 | 2026-09-21 |
| Testing the Addition of an Anti-Cancer Drug, Camonsertib, to Radiation Therapy for Recurrent Head and Neck Squamous Cell Carcinoma Biospecimen Collection, Camonsertib, Computed Tomography - Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Recurrent Head and Neck Squamous Cell Carcinoma | Phase 1 | Recruiting | National Cancer Institute (NCI) | 39 | 2027-02-13 | 2026-09-03 |
| Auditory-Cognitive Optimization Care Program for Older Adults With Hearing Loss and Cognitive Impairment Auditory-Cognitive Optimization Care Program (A-COP), Hearing Management and Newspaper-Reading Activities - Hearing Loss, Cognitive Impairment | Not applicable | Not yet recruiting | Taipei Medical University | 76 | 2027-02-01 | 2026-10-13 |
| A Study Testing Safety and Efficacy of Transtympanic Paliroden for the Treatment of Cochlear Synaptopathy in Participants With Chronic, Constant Tinnitus paliroden (CIL001), Placebo - Tinnitus, Bilateral, Cochlear Synaptopathy | Phase 1 / Phase 2 | Not yet recruiting | Cilcare SAS | 60 | 2027-01-01 | 2026-09-17 |
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Deglutition Disorders (832) · Hearing Loss (764) · Rhinitis, Allergic (679) · Nasopharyngeal Carcinoma (645) · Tinnitus (427) · Rhinitis, Allergic, Seasonal (384) · Oropharyngeal Neoplasms (367) · Hearing Loss, Sensorineural (336) · Head and Neck Neoplasms (310) · Laryngeal Neoplasms (256) · Pharyngitis (226) · Nasopharyngeal Neoplasms (224) · Otitis Media (219) · Asthma (213) · Rhinitis (212)
Pathological Conditions, Signs and Symptoms (3178) · Respiratory Tract Diseases (3155) · Nervous System Diseases (2859) · Signs and Symptoms (2712) · Ear Diseases (2703) · Neurologic Manifestations (2487) · Pharyngeal Diseases (2341) · Nose Diseases (1914) · Sensation Disorders (1860) · Hearing Disorders (1700) · Stomatognathic Diseases (1624) · Neoplasms by Site (1587) · Neoplasms (1571) · Otorhinolaryngologic Neoplasms (1441)
Cisplatin (257) · Radiotherapy, Intensity-Modulated (112) · Gemcitabine (99) · Radiotherapy (91) · Hearing Aids (81) · Mometasone Furoate (80) · Docetaxel (72) · Fluticasone (67) · Fluorouracil (64) · Sodium Chloride (59) · Dexamethasone (56) · toripalimab (51) · Cochlear Implants (49) · montelukast (46) · Carboplatin (45)
Sun Yat-sen University (215) · GlaxoSmithKline (112) · Cochlear (84) · Sonova AG (81) · Organon and Co (77) · Assiut University (64) · National Cancer Institute (NCI) (54) · Washington University School of Medicine (52) · Assistance Publique - Hôpitaux de Paris (48) · Eye & ENT Hospital of Fudan University (44) · Johns Hopkins University (43) · Oticon Medical (43) · Mayo Clinic (42) · M.D. Anderson Cancer Center (40) · NYU Langone Health (37)
United States (2314) · China (867) · France (502) · Canada (380) · Germany (320) · United Kingdom (277) · Turkey (Türkiye) (268) · Spain (184) · Belgium (180) · Taiwan (161) · Italy (156) · Switzerland (151) · South Korea (149) · Egypt (132) · Australia (123)
Nieto Luis, Master (21) · Luo Zhang (15) · Carl LeBel, PhD (14) · Jun Ma, M.D. (14) · Jay F Piccirillo, MD (11) · Ming-Yuan Chen, MD,PhD (11)
PMID 31150573, PMID 33710614, PMID 19001265, PMID 27158989, PMID 30207593, PMID 32926419, PMID 24184147, PMID 27686945, PMID 28837405, PMID 29584545, PMID 34341578, PMID 17270511, PMID 18331513, PMID 19140539, PMID 21439168, PMID 21441148, PMID 22464647, PMID 23374268, PMID 24035151, PMID 24836393, PMID 25133431, PMID 25685162, PMID 26171894, PMID 28602936, PMID 29656145, PMID 30213452, PMID 31178151, PMID 31723056, PMID 33492986, PMID 33548517, PMID 35240053, PMID 35724253, PMID 35997729, PMID 36746459, PMID 37185596, PMID 37951571, PMID 38197558, PMID 38507662, PMID 39035788, PMID 39970442, PMID 42572144, PMID 10734019, PMID 11297958, PMID 15385385, PMID 15817806, PMID 16137276, PMID 17021840, PMID 17030153, PMID 17135456, PMID 17917842
2023 (17), 2015 (16), 2018 (13), 2019 (13), 2025 (10), 2008 (9), 2009 (9), 2014 (9), 2016 (9), 2017 (9), U10CA180868 (9), P50DC007667 (7), P30CA138292 (6), U10CA180820 (6), 2005 (5)