Common Cold: Clinical Trials

159 completed, 20 unknown, 11 recruiting, 9 withdrawn. 90 Not applicable, 46 Phase 3, 28 Phase 2, 21 Phase 4, 9 Phase 1.

By phase and status

Phase	Trials	Status
Not applicable	90	Completed 66, Unknown 9, Recruiting 7, Active not recruiting 3, Not yet recruiting 3, Enrolling by invitation 1, Terminated 1
Phase 3	46	Completed 32, Withdrawn 7, Unknown 3, Recruiting 2, Suspended 1, Terminated 1
Phase 2	28	Completed 21, Terminated 2, Unknown 2, Not yet recruiting 1, Recruiting 1, Withdrawn 1
Phase 4	21	Completed 17, Unknown 2, Terminated 1, Withdrawn 1
Phase 1	9	Completed 9
Early Phase 1	1	Completed 1

Follow Common Cold: new trials by email Literature Review of Common Cold trials Research Report on Common Cold

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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Post-market Clinical Follow-up Study of an Isotonic Saline Solution for the Relief of Nasal Congestion in Infants and Toddlers Quinton Medical Nasal Health Baby® - Nasal Congestion, Common Cold		Not yet recruiting	Laboratoires Quinton International S.L.	83	2026-11-01	2026-10-13
Enhanced Telemedicine in Primary Care for Acute Respiratory Tract Infections Study Tele-Otoscope Enabled Primary Care, eBook-supported primary care - Acute Respiratory Tract Infection, Ear Infection	Not applicable	Not yet recruiting	University of Pittsburgh	450	2026-11-01	2026-09-29
Observational Study of RHINOSEDAL in Acute Nasal Obstruction RHINOSEDAL - Nasal Obstruction, Common Cold		Not yet recruiting	Laboratoires Elerte	126	2026-10-15	2026-06-02
Observational Study of SIROPSEDAL in Acute Cough Acute Cough, Upper Respiratory Tract Infection		Not yet recruiting	Laboratoires Elerte	124	2026-10-15	2026-06-04
Effect of Immune X on Common Cold Incidence in Healthy Adults Immune X, Placebo - Common Cold, Upper Respiratory Tract Infection (URTI)	Not applicable	Recruiting	Givaudan France Naturals	160	2026-10-09	2026-10-13
The Effect of the Cold Arm Sling Elevation Pillow on Postoperative Anxiety and Comfort in Children Cold and arm sling elevation pillow, Standard postoperative care - Upper Extremity Fractures, Postoperative Anxiety	Not applicable	Not yet recruiting	Istanbul University - Cerrahpasa	80	2026-09-01	2026-07-07
A Novel Cold and Flu Herbal Blend for Reducing the Duration and Severity of the Common Cold Novel Herbal Cold & Flu Blend, Placebo - URTI, Common Cold	Phase 2	Not yet recruiting	RDC Clinical Pty Ltd	300	2026-07-01	2026-06-11
Fixed-dose Combination of 1000 mg Dipyrone Monohydrate + 60 mg Caffeine + 4 mg Chlorpheniramine Maleate in Improving Symptoms of the Common Cold and Flu in Adults dipyrone monohydrate 1000 mg + chlorpheniramine maleate 4 mg + caffeine 60 mg, dipyrone monohydrate 500 mg + chlorpheniramine maleate 2 mg + caffeine 30 mg, Placebo - Common Cold/Flu, Nasal Congestion	Phase 3	Recruiting	Brainfarma Industria Química e Farmacêutica S/A	620	2026-05-08	2026-06-16
The Role of NaV1.8 in Human Pain Models Suzetrigine, Lidocaine (drug), Control Solution - Pain, Acute Pain	Early Phase 1	Completed	Medical University of Vienna	67	2026-04-21	2026-06-24
Evaluation of a Hypertonic Seawater Aerosol Therapy Solution in Adults and Children Treatment (22‰ Hypertonic seawater aerosol therapy solution) - Upper Resp Tract Infection, Rhinitis Acute	Not applicable	Completed	Laboratoires Gilbert	110	2026-04-21	2026-07-23
Sex Differences in Cold-Induced Changes in Maximal Fat Oxidation Cold temperature, Room Temperature - Exercise	Not applicable	Recruiting	Colorado State University	20	2026-04-15	2026-05-15
RhinAV_Evaluation of Treatments for Acute Viral Rhinitis, Rhinosinusitis, and Rhinopharyngitis PIR, NS, NHE - Rhinitis Acute, Rhinitis Viral	Not applicable	Recruiting	University Hospital, Clermont-Ferrand	150	2026-02-25	2026-06-15
Efficacy and Safety of Jinhua Qinggan Granules (JHQG) for the Use of Acute Upper Respiratory Infection Jinhua Qinggan Granules, Placebo - Acute Rhinitis, Acute Pharyngitis	Phase 3	Completed	University of Karachi	546	2026-01-24	2026-07-28
Omega-Cold Supplementation With Free Fatty Acids for the Prevention of Respiratory Infections in Adults. Omega-3 oil with 2% Free Fatty Acids, Vegatable oil - Respiratory Infections	Not applicable	Recruiting	Landspitali University Hospital	400	2025-12-19	2026-08-28
Immune Defense Protein Impact On Respiratory Immune Outcomes Immune Defense Protein 50mg Dose, IDP 200mg Dose, Matching Placebo - Upper Respiratory Disease, Influenza	Not applicable	Recruiting	Quantec Ltd	300	2025-12-05	2026-03-12
Cryotherapy on Muscle Function Cold pack application, Cold spray application - Cold, Cryotherapy	Not applicable	Completed	Okan University	52	2025-05-15	2025-06-06
Phase 3 Clinical Trial to Evaluate Paracetamol /Fexofenadine /Phenylephrine in Flu and Cold Treatment Experimental drug (paracetamol 500mg / fexofenadine 60mg / phenylephrine 20mg), Placebo - Cold, Flu Symptom	Phase 3	Completed	Eurofarma Laboratorios S.A.	567	2025-03-26	2026-09-22
Assessment of the Effects of Acute Exposure to Cold and Heat on Appetite Appetite		Not yet recruiting	Direction Centrale du Service de Santé des Armées	40	2025-02-01	2025-02-05
Evaluation of Nasal Biomarkers for Objective Assessment of Disease Severity in Respiratory Disorders ABEL microsampler device - Chronic Obstructive Pulmonary Disease (COPD), Asthma Patients		Completed	Diag-Nose Medical Pty Ltd	111	2025-01-08	2026-04-13
Efficacy of Winterized Pistacia Lentiscus Oil in Reducing Purulent Bacterial Overinfection of Pediatric Rhinitis Winterized Pistacia Lentiscus Oil Nasal Drops (Bactorinol®), Saline Solution (0.9% NaCl) - Rhinitis Acute	Not applicable	Completed	Liaquat University of Medical & Health Sciences	105	2025-01-02	2025-06-29

Showing 20 of 218. Sign in to see all of them.

Narrower conditions

Influenza, Human (47)  ·  Respiratory Tract Infections (36)  ·  Cough (17)  ·  Nasal Obstruction (14)  ·  Pharyngitis (14)  ·  Rhinitis (10)  ·  Rhinitis, Allergic (9)  ·  Virus Diseases (8)  ·  COVID-19 (7)  ·  Rhinosinusitis (7)  ·  Asthma (6)  ·  Inflammation (5)  ·  Headache (4)  ·  Motor Activity (4)

Broader conditions

RNA Virus Infections (217)  ·  Respiratory Tract Diseases (217)  ·  Infections (216)  ·  Picornaviridae Infections (216)  ·  Virus Diseases (210)  ·  Respiratory Tract Infections (182)  ·  Orthomyxoviridae Infections (47)  ·  Pathological Conditions, Signs and Symptoms (45)  ·  Otorhinolaryngologic Diseases (42)  ·  Signs and Symptoms (32)  ·  Respiration Disorders (31)  ·  Nose Diseases (30)  ·  Pharyngeal Diseases (19)  ·  Signs and Symptoms, Respiratory (19)  ·  Immune System Diseases (18)

Interventions

Acetaminophen (13)  ·  pentanedioic acid imidazolyl ethanamide (7)  ·  Aspirin (6)  ·  Phenylephrine (6)  ·  Acetylcysteine (4)  ·  Echinacea extract (4)  ·  Pseudoephedrine (4)  ·  Sucrose (4)  ·  Caffeine (3)  ·  Exercise (3)  ·  Lidocaine (3)  ·  4'-galactooligosaccharide (2)  ·  Ascorbic Acid (2)  ·  Chlorpheniramine (2)  ·  Cold Temperature (2)

Sponsors

GlaxoSmithKline (9)  ·  Valenta Pharm JSC (9)  ·  Ache Laboratorios Farmaceuticos S.A. (6)  ·  Bayer (5)  ·  Enzymatica AB (5)  ·  EMS (4)  ·  Acibadem University (3)  ·  Hospital de Clinicas de Porto Alegre (3)  ·  Laboratoires Gilbert (3)  ·  Lallemand Pharma AG (3)  ·  Marinomed Biotech AG (3)  ·  Novartis (3)  ·  University of Florida (3)  ·  University of Wisconsin, Madison (3)  ·  A. Vogel AG (2)

Countries

United States (47)  ·  United Kingdom (20)  ·  Russia (13)  ·  Brazil (12)  ·  Germany (11)  ·  Italy (10)  ·  Canada (9)  ·  France (9)  ·  Turkey (Türkiye) (9)  ·  China (8)  ·  Austria (6)  ·  Poland (6)  ·  Sweden (5)  ·  Bulgaria (4)  ·  Spain (4)

Top investigators

Ekaterina Zakharova, MD, PhD (5)  ·  Bobbi Langkamp-Henken, PhD, RD (3)  ·  Bruce Barrett, MD PhD (2)  ·  Deborah Gentile, MD (2)  ·  Luis Felipe C Schmidt, MD (2)  ·  Marisa B Costa, MS (2)  ·  Ronald B Turner, MD (2)  ·  Ronald Turner, MD (2)  ·  Ying An, Ph.D (2)  ·  Akash Pandhare, MD. Ph.D. (1)  ·  Alistair Woodward, PhD (1)

Results publications

PMID 24261438, PMID 10511934, PMID 10719291, PMID 12517470, PMID 12719068, PMID 15117622, PMID 15288679, PMID 15293621, PMID 15379582, PMID 15561835, PMID 15817806, PMID 16049208, PMID 16061320, PMID 16218509, PMID 17264159, PMID 17474541, PMID 17531694, PMID 18226798, PMID 18676527, PMID 19145994, PMID 19713445, PMID 20881023, PMID 21143077, PMID 21173411, PMID 21366172, PMID 21525194, PMID 21526943, PMID 21763309, PMID 22046723, PMID 22209916, PMID 22336807, PMID 22412063, PMID 22479361, PMID 22547128, PMID 22701675, PMID 22767165, PMID 23113460, PMID 23270519, PMID 23279613, PMID 23369797, PMID 23561463, PMID 23583042, PMID 23716043, PMID 23855280, PMID 24003241, PMID 24160728, PMID 24415465, PMID 24432596, PMID 24468694, PMID 24626238

NIH funding

1RC1LM010424-01 (1), 2005 (1), 2009 (1), 2014 (1), R01AI201390 (1), R01AT001428 (1), R01AT006970 (1), U01AI160090 (1), U01CI000442 (1)