593 completed, 231 unknown, 119 recruiting, 89 terminated. 335 Phase 4, 270 Phase 3, 212 Phase 2, 179 Not applicable, 102 Phase 1.
Follow Aspirin: new trials by email Literature Review of Aspirin trials Research Report on Aspirin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Timed Aspirin Chronobiome Study Aspirin 81 mg, Celecoxib 200mg capsule - Healthy | Early Phase 1 | Not yet recruiting | University of Pennsylvania | 60 | 2027-12-01 | 2026-05-29 |
| Aspirin Versus Clopidogrel in Chronic Coronary Syndrome in Arabian Gulf Countries Aspirin, Clopidgrel 75 mg daily - Chronic Coronary Syndrome | Phase 3 | Not yet recruiting | Khalid F Alhabib | 6740 | 2027-04-01 | 2026-05-11 |
| Spontaneous Coronary Artery Dissection - AntipLatelet Therapy Intensity in Guided coNservative Management (SCAD-ALIGN) Trial Acetylsalicylic acid ASA, ASA plus Clopidogrel - SCAD, ACS (Acute Coronary Syndrome) | Phase 4 | Not yet recruiting | Universitätsklinikum Hamburg-Eppendorf | 3518 | 2027-03-01 | 2026-10-16 |
| Low Dose Aspirin to Lower Inflammation and Prevent Endometrial Cancer in Postmenopausal Women With Non-atrophic Endometrial Changes and Pain Biospecimen Collection, Low-Dose Aspirin, Patient Observation - Endometrial Carcinoma | Phase 4 | Not yet recruiting | Mayo Clinic | 20 | 2027-02-12 | 2026-08-05 |
| The Safety and Efficacy of Human Umbilical Cord Mesenchymal Stem Cells (19#iSCLife®-ACI) in the Treatment of Acute Cerebral Infarction Allogeneic umbilical cord mesenchymal stem cells (SCLnow 19#), Aspirin Tablet - Cerebral Infarction | Phase 1 | Suspended | Sclnow Biotechnology Co., Ltd. | 40 | 2026-12-31 | 2026-04-23 |
| A Pilot Study to Investigate Platelet Reactivity in Patients With Elevated Lipoprotein(a) and Its Response to Antiplatelet Therapy Aspirin, Clopidogrel - Cardiovascular Prevention | Not applicable | Not yet recruiting | François MACH | 60 | 2026-11-01 | 2026-07-22 |
| Efficacy and Safety of Immunoglobulin Plus Firsekibart in Patients With Kawasaki Disease IVIG, Aspirin, Firsekibart - Kawasaki Disease | Phase 2 / Phase 3 | Not yet recruiting | Children's Hospital of Fudan University | 90 | 2026-11-01 | 2026-10-22 |
| Tegoprazan-Aspirin Drug Interaction in Healthy Adult Male Volunteers Aspirin, Tegoprazan, Tegoprazan + Aspirin - Healthy Adult Male | Phase 1 | Not yet recruiting | HK inno.N Corporation | 34 | 2026-10-14 | 2026-10-01 |
| Personalized Care for Prenatal Stress Reduction & Prevention of Preterm Birth (PTB) Disparities Care coordination, Electronic massage, support gift #1 - Preterm Birth Complication, Preterm Birth | Not applicable | Not yet recruiting | University of North Carolina, Chapel Hill | 1228 | 2026-10-01 | 2026-09-29 |
| DAN-RELEASE - Reconsidering Long-Term Aspirin in the Elderly Patients With Stable Ischemic Heart Disease Continuation of daily low-dose Aspirin, Discontinuation of daily low-dose Aspirin - Ischemic Heart Disease, Ischemic Heart Disease Chronic | Phase 4 | Recruiting | Odense University Hospital | 7000 | 2026-09-30 | 2026-10-05 |
| A Clinical Trial of Antiplatelets in Psoriasis Aspirin, Clopidogrel, Placebo - Psoriasis (PsO), Psoriatic Arthritis (PsA) | Phase 4 | Not yet recruiting | NYU Langone Health | 60 | 2026-09-01 | 2026-08-05 |
| Combination Immunotherapy Treatment for Glioblastoma Including BreakVax ImmunoTreatment (Designed and Manufactured Per Patient), Chemotherapy and Anti PD-1 Therapy BreakVax, Ipilimumab 2.5 mg, Pembrolizumab - Glioblastoma (GBM) | Phase 1 / Phase 2 | Not yet recruiting | BreakBio Corp | 10 | 2026-09-01 | 2026-08-19 |
| Combination Immunotherapy Treatment for Locally Advanced Unresectable or Metastatic, PD-L1 Negative (CPS<10), gBRCA Negative, Triple Negative Breast Cancer Including BreakVax ImmunoTreatment (Designed and Manufactured Per Patient), Chemotherapy and Anti PD-1 Therapy BreakVax, Ipilimumab 2.5 mg, Pembrolizumab - Triple-Negative Breast Cancer (TNBC) | Phase 1 / Phase 2 | Not yet recruiting | BreakBio Corp | 10 | 2026-09-01 | 2026-08-19 |
| Optimal Anti-Thrombotic Management Following Percutaneous Left Atrial Appendage Occlusion Half-Dose of novel OAC, Low-dose ASA - Atrial Fibrillation (AF) | Phase 3 | Recruiting | Texas Cardiac Arrhythmia Research Foundation | 234 | 2026-09-01 | 2026-10-05 |
| Low Dose Aspirin vs Placebo in Prevention of Recurrent Spontaneous Preterm Labour Low-dose Aspirin, Placebo - Preterm Labor, Premature Birth | Not applicable | Not yet recruiting | University of Health Sciences Lahore | 162 | 2026-08-20 | 2026-08-12 |
| Study on Anti-Thrombotic Regimens for Secondary Prevention in Ischemic Stroke Patients With Possible Benefit From Anticoagulation Therapy Rivaroxaban, or Edoxaban , or Apixaban , or Dabigatran, Aspirin - Stroke, Acute Ischemic Stroke | Phase 3 | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 680 | 2026-08-15 | 2026-08-05 |
| Efficacy and Safety of Ropeginterferon Alfa 2b (P1101) for Patients With Polycythemia Vera Ropeginterferon alfa-2b, Phlebotomy and aspirin - Polycythemia Vera, Myeloproliferative Neoplasm | Phase 4 | Withdrawn | PharmaEssentia | 2026-08-01 | 2026-07-31 | |
| Aspirin Monotherapy Versus Sequential Warfarin-Aspirin Therapy After TAVR in Patients With Pure Aortic Regurgitation Aspirin, Warfarin - Aortic Regurgitation Disease | Not applicable | Recruiting | Shanghai Zhongshan Hospital | 1172 | 2026-07-18 | 2026-08-10 |
| Efficacy and Safety of Indobufen, Aspirin, Cilostazol and Clopidogrel in the Treatment of Ischemic Stroke indubufen, aspirin, clopidogrel, cilostazol - Acute Ischemic Stroke | Not yet recruiting | Nanfang Hospital, Southern Medical University | 2000 | 2026-07-01 | 2026-05-22 | |
| HR-MRI-Directed Tirofiban Therapy for Late-Window Acute Ischemic Stroke (TIAN) Tirofiban, dual antiplatelet therapy - Stroke, Acute, Stroke, Ischemic | Phase 3 | Recruiting | Weifang Medical University | 458 | 2026-06-22 | 2026-06-25 |
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Coronary Artery Disease (120) · Stroke (84) · Ischemic Stroke (80) · Cardiovascular Diseases (64) · Pre-Eclampsia (58) · Acute Coronary Syndrome (47) · Myocardial Infarction (44) · Thrombosis (43) · Peripheral Arterial Disease (35) · Atrial Fibrillation (34) · Atherosclerosis (31) · Coronary Disease (29) · Hemorrhage (29) · Colorectal Neoplasms (28) · Venous Thromboembolism (28)
Bayer (37) · AstraZeneca (13) · Assiut University (12) · Xijing Hospital (12) · Assistance Publique - Hôpitaux de Paris (11) · Beijing Tiantan Hospital (11) · Bristol-Myers Squibb (11) · Boehringer Ingelheim (10) · National Cancer Institute (NCI) (10) · Peking Union Medical College Hospital (9) · Second Affiliated Hospital, Zhejiang University, School of Medicine (9) · Seoul National University Hospital (9) · The First Affiliated Hospital with Nanjing Medical University (9) · University of Florida (9) · Vanderbilt University (9)
United States (347) · China (182) · Canada (95) · South Korea (88) · United Kingdom (78) · France (63) · Italy (59) · Germany (49) · Spain (48) · Denmark (43) · Switzerland (39) · Netherlands (37) · Belgium (36) · Brazil (30) · Japan (29)
Dominick J Angiolillo, MD, PhD (5) · Joo-Yong Hahn, MD, PhD (4) · Paul Gurbel, MD (4) · Gang Zhao, M.D. (3) · Juan J Badimon, PhD (3) · Leslie Skeith, MD (3) · Marc Rodger, MD (3) · Peter M Maurer, MPH (3) · Rehan Qayyum, MD (3) · Seung-Jung Park, MD, PhD (3)
PMID 35224730, PMID 37489818, PMID 32358837, PMID 36700520, PMID 19717846, PMID 19923168, PMID 27959700, PMID 30146931, PMID 31867054, PMID 34473343, PMID 40875095, PMID 11519503, PMID 11786451, PMID 12807523, PMID 15842354, PMID 17261652, PMID 19482214, PMID 20194878, PMID 20231231, PMID 20650435, PMID 21079055, PMID 21873419, PMID 21873632, PMID 22212857, PMID 22795280, PMID 23517020, PMID 24679062, PMID 25173339, PMID 26494395, PMID 27160892, PMID 27640943, PMID 28527771, PMID 28657417, PMID 29132879, PMID 29132880, PMID 29217001, PMID 29588190, PMID 29939940, PMID 30015064, PMID 30158069, PMID 31535314, PMID 33394942, PMID 34658014, PMID 35833913, PMID 37565307, PMID 40775758, PMID 10591382, PMID 10648016, PMID 10851208, PMID 1100130
2014 (11), 2016 (7), 2018 (7), 2015 (5), 2023 (5), 2025 (5), 2004 (3), 2009 (3), 2017 (3), P01CA108671 (3), P30CA016672 (3), 2005 (2), 2008 (2), K23HL105897 (2), N01CN00031 (2)