8 completed, 2 withdrawn, 1 not yet recruiting, 1 terminated. 13 Phase 1, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 13 | Completed 8, Withdrawn 2, Not yet recruiting 1, Terminated 1, Unknown 1 |
| Phase 2 | 5 | Completed 4, Withdrawn 1 |
Follow Respiratory Failure: new trials by email Literature Review of Respiratory Failure trials Research Report on Respiratory Failure
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Different Proprioceptive Neuromuscular Facilitation Techniques Versus Flow Trigger Sensitivity on Weaning Off Mechanical Ventilation Flow trigger sensitivity group, Active proprioceptive facilitation technique ( active PNF) technique, Passive proprioceptive facilitation technique ( passive PNF) technique - Respiratory Failure | Phase 1 | Not yet recruiting | Beni-Suef University | 84 | 2025-02-20 | 2025-02-18 |
| Pectointercostal Fascial Plane Block (PIFB) Alone Versus PIFB With Rectus Sheath Block (RSB) in Cardiac Surgery Rectus sheath block with bupivacaine - Coronary Artery Disease, Postoperative Pain | Phase 1 | Completed | Medical College of Wisconsin | 62 | 2023-06-19 | 2025-11-17 |
| CONFOCAL-2 Interventional Pilot Study Autoregulation-based precision blood pressure management - Critical Illness, Respiratory Failure | Phase 1 / Phase 2 | Completed | Queen's University | 16 | 2022-07-29 | 2025-12-22 |
| Effects of mTOR Inhibition With Sirolimus (RAPA) in Patients With COVID-19 to Moderate the Progression of ARDS Rapamycin, Placebo - Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS), Respiratory Failure | Phase 1 / Phase 2 | Withdrawn | The University of Texas Health Science Center at San Antonio | 2021-04-01 | 2021-06-01 | |
| Use of Angiotensin-(1-7) in COVID-19 Angiotensin-(1-7), Placebo - Infection, Coronavirus, Respiratory Failure | Phase 1 / Phase 2 | Completed | Erasme University Hospital | 112 | 2020-08-05 | 2021-11-09 |
| Nebulized Hypertonic Saline for Mechanically Ventilated Children Hypertonic saline (3%), Placebo (0.9% saline) - Respiratory Failure | Phase 1 / Phase 2 | Completed | University Hospitals Cleveland Medical Center | 18 | 2013-10-01 | 2016-06-28 |
| Safety Study of Nebulized Sodium Nitroprusside in Adult Acute Lung Injury Sodium Nitroprusside - Acute Lung Injury, Acute Respiratory Distress Syndrome | Phase 1 | Unknown | Mount Sinai Hospital, Canada | 30 | 2012-05-01 | 2012-06-14 |
| Non-invasive Neurally Adjusted Ventilatory Assist non-invasive neurally adjusted ventilatory assist - Respiratory Failure | Phase 1 | Withdrawn | Insel Gruppe AG, University Hospital Bern | 2010-11-01 | 2015-07-23 | |
| Implementation of Telemonitoring in Chronic Heart or Lung Failure CE marked Philips Motiva system - COPD, Heart Failure | Phase 1 | Completed | Royal Brompton & Harefield NHS Foundation Trust | 85 | 2010-06-01 | 2014-07-03 |
| Effect of Inspiratory Muscle Training on Duration of Mechanical Ventilation Support IMST, Sham IMST - Respiratory Failure | Phase 1 / Phase 2 | Completed | University of Florida | 76 | 2010-05-01 | 2013-12-11 |
| How Your Patients' Non-REM Sleep Changes On Sedatives in the Intensive Care Units Dexmedetomidine, GABA agonist - Delirium, Respiratory Failure | Phase 1 | Terminated | Vanderbilt University Medical Center | 6 | 2009-01-01 | 2017-06-05 |
| Mechanical Ventilation Controlled by the Electrical Activity of the Patient's Diaphragm - Effects on Cardiac Performance Neurally adjusted ventilatory assist (NAVA) provided by a commercially available mechanical ventilator (Servo i, Maquet Critical Care, Solna, Sweden). - Respiratory Failure, Cardiac Failure | Phase 1 | Completed | Insel Gruppe AG, University Hospital Bern | 15 | 2008-03-01 | 2011-07-19 |
| Inspiratory Muscle Training in Ventilator Dependent Patients inspiratory muscle strength training - Failure to Wean, Respiratory Failure | Phase 1 | Completed | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 150 | 2004-02-01 | 2009-11-09 |
Respiratory Insufficiency (13) · Acute Lung Injury (2) · Delirium (2) · Heart Failure (2) · Respiratory Distress Syndrome (2) · COVID-19 (1) · Coronary Artery Disease (1) · Coronavirus Infections (1) · Critical Illness (1) · Hypoxia (1) · Lung Injury (1) · Pain, Postoperative (1) · Pulmonary Atelectasis (1) · Pulmonary Disease, Chronic Obstructive (1) · Respiratory Aspiration (1)
Respiration Disorders (13) · Respiratory Tract Diseases (13) · Pathological Conditions, Signs and Symptoms (6) · Lung Diseases (4) · Pathologic Processes (4) · Signs and Symptoms (4) · Cardiovascular Diseases (3) · Heart Diseases (3) · Neurologic Manifestations (3) · Confusion (2) · Coronaviridae Infections (2) · Disease Attributes (2) · Infections (2) · Mental Disorders (2) · Nervous System Diseases (2)
Interactive Ventilatory Support (2) · Bupivacaine (1) · Dexmedetomidine (1) · GABA Agonists (1) · Lorazepam (1) · Methods (1) · Midazolam (1) · Nitroprusside (1) · Noninvasive Ventilation (1) · Propofol (1) · Saline Solution (1) · Saline Solution, Hypertonic (1) · Sirolimus (1) · Sodium Chloride (1) · Solutions (1)
Insel Gruppe AG, University Hospital Bern (2) · Beni-Suef University (1) · Erasme University Hospital (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · Medical College of Wisconsin (1) · Mount Sinai Hospital, Canada (1) · Queen's University (1) · Royal Brompton & Harefield NHS Foundation Trust (1) · The University of Texas Health Science Center at San Antonio (1) · University Hospitals Cleveland Medical Center (1) · University of Florida (1) · Vanderbilt University Medical Center (1)
United States (6) · Canada (2) · Brazil (1) · Egypt (1) · Switzerland (1) · United Kingdom (1)
Lukas Brander, MD (2) · Ana Martins Valle (1) · Anatole D Martin, Ph D, PT (1) · Andrea Gabrielli, MD (1) · Anita K Simonds, MD (1) · Anne Castro (1) · Dean L Kellogg, MD, PhD (1) · Elosie Harman, MD (1) · Filippo Annoni (1) · Joseph Layon, MD (1) · Lawrence Caruso, MD (1) · Maher Baz, MD (1) · Micheal Banner, Ph D (1) · Paul Davenport, Ph D (1) · Paula L Watson, MD (1)