954 completed, 191 recruiting, 116 terminated, 115 withdrawn. 688 Not applicable, 218 Phase 2, 133 Phase 1, 107 Phase 4, 36 Phase 3.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Maximizing HPV Vaccination: Real-time Reminders, Guidance, and Recommendations - Part 4: Feasibility Trial Protect Me 4 Application + External Quality Improvement Support, Protect Me 4 Application Alone - Human Papillomavirus (HPV) Vaccines | Not applicable | Not yet recruiting | University of Florida | 1296 | 2027-09-15 | 2026-09-14 |
| Multiparametric Lung MRI With Diffusion-Weighted Imaging in Lung-RADS 4 Lesion Characterization Multiparametric chest MRI with diffusion-weighted imaging - Solitary Pulmonary Nodule, Multiple Pulmonary Nodules | Not yet recruiting | University of Florida | 30 | 2027-01-01 | 2026-08-19 | |
| A Pilot Study on the Efficacy of Oral Low Dose Naltrexone for Vulvodynia Low Dose Naltrexone - Vulvodynia | Phase 2 | Not yet recruiting | University of Florida | 20 | 2027-01-01 | 2026-10-09 |
| Gaze and Gait Training With rTMS Repetitive Transcranial Magnetic Stimulation (rTMS), Gait training, Gaze training - Mild Cognitive Impairment | Not applicable | Not yet recruiting | University of Florida | 30 | 2027-01-01 | 2026-05-06 |
| Neoadjuvant Enfortumab Vedotin Plus Pembrolizumab in Muscle-Invasive Bladder Cancer and Upper Tract Urothelial Carcinoma enfortumab vedotin and pembrolizumab (EV/P) - Urothelial Carcinoma (UC) | Phase 2 | Not yet recruiting | University of Florida | 39 | 2026-12-01 | 2026-09-14 |
| Kava Aging and Mobility Study AB-free kava, Placebo - Old Adults, Sleep Quality | Early Phase 1 | Not yet recruiting | University of Florida | 40 | 2026-12-01 | 2026-08-31 |
| Ivermectin Combined With Immune Checkpoint Inhibition in Cancer (ICONIC) Intermediate-dose ivermectin, High-dose ivermectin - Solid Tumor, Adult | Phase 2 | Not yet recruiting | University of Florida | 80 | 2026-12-01 | 2026-10-13 |
| AIIM Trial: Personalized Medicine Approach to Kidney Allograft Function Phenotypic Personalized Medicine Dosing, Standard of Care Dosing - Kidney Transplant Rejection | Not applicable | Not yet recruiting | University of Florida | 34 | 2026-12-01 | 2026-02-10 |
| Randomized In-Vivo Comparison of 3D-Printed and Thermoformed Clear Aligners: A Multi-Subject, Time-Dependent Analysis of Adaptation and Trueness Device: Invisalign Passive Clear Aligner, Spark Passive aligners, Zendura passive aligner - Adaptation of Different Types of Clear Aligners | Not applicable | Not yet recruiting | University of Florida | 20 | 2026-11-30 | 2026-06-12 |
| Repurposing Mefloquine for Pancreatic Cancer Treatment Mefloquine, Modified FOLFIRINOX, gemcitabine and nab paclitaxel - Pancreatic Ductal Adenocarcinoma | Phase 1 | Not yet recruiting | University of Florida | 36 | 2026-11-01 | 2026-10-15 |
| IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ Newly Diagnosed and Recurrent Pediatric High-grade Glioma (pHGG) and Newly Diagnosed Diffuse Intrinsic Pontine Glioma (ndDIPG) Ex-Vivo expanded autologous IL-8 receptor (CXCR2) modified CD70 CAR (8R-70CAR) T cells - High-grade Glioma, Diffuse Intrinsic Pontine Glioma | Phase 1 | Not yet recruiting | University of Florida | 24 | 2026-11-01 | 2026-09-09 |
| Universal Immunization to Fortify Immunotherapy Efficacy and Response Pfizer-BioNTech mRNA COVID-19 vaccine - Stage 4 NSCLC | Phase 2 | Not yet recruiting | University of Florida | 500 | 2026-11-01 | 2026-09-29 |
| IL-8 Receptor Modified Patient-Derived Activated CD70 CAR T Cell Therapy in Adults With Brain Metastases Ex-Vivo expanded autologous IL-8 receptor (CXCR2) modified CD70 CAR (8R-70CAR) T cells, CD70 IHC assay - Brain Metastases | Phase 1 | Recruiting | University of Florida | 12 | 2026-10-13 | 2026-10-16 |
| Alcohol Sensitivity Among Older Adults Who Consume Alcohol Alcohol (Oral), Placebo Control - Healthy Adult Participants | Not applicable | Recruiting | University of Florida | 80 | 2026-10-03 | 2026-09-30 |
| Methylphenidate and Response to Alcohol Cues Methylphenidate Pill, Placebo Pill - Alcohol Use Disorder | Phase 2 | Not yet recruiting | University of Florida | 50 | 2026-10-01 | 2026-08-20 |
| Eplerenone and IOP in Healthy Adults Eplerenone, Microcrystalline Cellulose NF (placebo) - Intraocular Pressure (IOP), Healthy Adult | Phase 1 | Not yet recruiting | University of Florida | 30 | 2026-10-01 | 2026-08-31 |
| PPI Dosing Per CYP2C19 Genotype CYP2C19 based dosing Proton Pump Inhibitors, Conventional proton pump inhibitor dose - Gastroesophageal Reflux Disease With Esophagitis | Phase 4 | Not yet recruiting | University of Florida | 200 | 2026-10-01 | 2026-09-28 |
| Using e-Technologies to Maximize Physical Activity After Cancer Treatment Cancer Exercise App - Cancer | Not applicable | Not yet recruiting | University of Florida | 750 | 2026-10-01 | 2026-08-27 |
| Evaluation of Novel Iron-based Lymphatic Mapping Agent, Magtrace, for Delayed Sentinel Lymph Node Biopsy (SLNB) in Ductal Carcinoma In-Situ (DCIS) Magtrace - Ductal Carcinoma in Situ | Phase 2 | Suspended | University of Florida | 30 | 2026-10-01 | 2026-09-11 |
| Enhancing Rehabilitation in Aging Study (ERAS) Istradefylline 20 mg, Placebo, Acute Intermittent Hypoxia (AIH) - Adults | Phase 1 / Phase 2 | Not yet recruiting | University of Florida | 38 | 2026-10-01 | 2026-07-15 |
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Dominick J Angiolillo, MD, PhD (14) · Bobbi Langkamp-Henken, PhD, RD (13) · Wendy J Dahl, PhD (10) · Demetra Christou, PhD (9) · Dominick Angiolillo, MD, PhD (9) · Peter Draganov, MD (9) · Philip Efron, MD (8) · Liwei Gu, PhD (7) · Susan S Percival, PhD (7) · Ashley Ghiaseddin, MD (6) · Carl J Pepine, MD (6) · Emily K Plowman, PhD (6) · Emily Plowman, PhD (6) · Francesco Franchi, MD (6) · Marie-Carmelle Elie, MD (6)
PMID 40875095, PMID 42338740, PMID 39716214, PMID 20606150, PMID 23640952, PMID 24975234, PMID 25527663, PMID 26765812, PMID 28115488, PMID 29523524, PMID 29925376, PMID 30753254, PMID 32972877, PMID 35651964, PMID 38353215, PMID 38747311, PMID 41218853, PMID 41464305, PMID 10084038, PMID 10623691, PMID 10747150, PMID 10782340, PMID 11013547, PMID 11050519, PMID 11687311, PMID 11742607, PMID 11892709, PMID 12052996, PMID 12117397, PMID 12233992, PMID 12615796, PMID 12885347, PMID 12957348, PMID 14568122, PMID 14617717, PMID 14657064, PMID 15147429, PMID 15187199, PMID 15266208, PMID 15320564, PMID 15364899, PMID 15381674, PMID 1550287, PMID 15553310, PMID 15911902, PMID 16075824, PMID 16153580, PMID 16278523, PMID 16412970, PMID 16458134
P30AG028740 (18), R01HL132448 (6), UL1TR001427 (6), U01HG007269 (5), U01HG010225 (5), P30AG059297 (4), U01DE016747 (4), UL1TR000064 (4), P01AA029547 (3), P50GM111152 (3), R01CA207689 (3), R01HD071779 (3), R01NS120924 (3), R35GM140806 (3), U01GM074492 (3)