247 completed, 44 recruiting, 36 unknown, 25 terminated. 102 Phase 3, 101 Phase 2, 89 Phase 1, 70 Phase 4, 49 Not applicable.
Follow Solutions: new trials by email Literature Review of Solutions trials Research Report on Solutions
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Betadine Vaginal Cleansing Before Cesarean Section to Reduce Postoperative Infectious Morbidity Povidone-iodine 5% solution - Cesarean Section, Surgical Site Infection | Not applicable | Not yet recruiting | Mohamed Mousa Mohamed Mousa | 600 | 2027-05-01 | 2026-07-20 |
| Comparative Study on Unani Formulation Vs Active Control in Plaque Psoriasis Marham Asfedaj, Mundij wa Mushil Sawda (Unani Oral decoction), Coal tar 1% & Salicylic acid 3 % solution - Chronic Plaque Psoriasis, Plaque Psoriasis | Phase 2 | Not yet recruiting | National Institute of Unani Medicine, Bengaluru | 54 | 2027-04-01 | 2026-09-25 |
| Stratification and Treatment in Early Psychosis Study -ASSIST CBD 100 mg/mL Oral Solution, Placeb - Treatment Resistant Psychosis, Psychosis | Phase 3 | Not yet recruiting | University of Oxford | 250 | 2027-01-01 | 2026-10-08 |
| A Study to Investigate the Transition of Children From 'Artisanal" Cannabidiol (CBD) to Epidiolex Epidiolex 100 mg/mL Oral Solution - Dravet Syndrome (DS), Lennox-Gastaut Syndrome (LGS) | Phase 4 | Not yet recruiting | Elizabeth Donner | 25 | 2027-01-01 | 2026-09-11 |
| A Study of TAK-664 in People With Primary Immunodeficiency Diseases Who Have Not Yet Been Treated With Immunoglobulins TAK-664 - Primary Immunodeficiency Diseases (PID) | Phase 4 | Not yet recruiting | Takeda | 9 | 2026-11-01 | 2026-09-08 |
| Microneedling-Assisted Metformin, Tranexamic Acid, and Modified Kligman's Formula for Melasma Metformin 30% Topical Lotion, Tranexamic Acid 0.5% Topical Solution, Modified Kligman's Formula - Melasma (Facial Melasma) | Phase 4 | Enrolling by invitation | Sameh Sarsik | 80 | 2026-10-25 | 2026-10-27 |
| Rapid Rehydration for Severe Hypernatremia Intravenous Dextrose 5% solution - Hypernatremia | Phase 2 | Recruiting | Columbia University | 80 | 2026-10-22 | 2026-10-27 |
| Stratification and Treatment in Early Psychosis Study - ENHANCE CBD 100 mg/mL Oral Solution, Placebo - Psychosis, First Episode Psychosis | Phase 3 | Recruiting | University of Oxford | 250 | 2026-10-05 | 2026-10-08 |
| Adjunctive Probiotic Therapy in Major Depressive Disorder (ProMOOD) OMNi-BiOTiC® STRESS Repair, Matched Placebo Powder for Oral Solution - Depression / Major Depressive Disorder | Not applicable | Not yet recruiting | University Maribor | 200 | 2026-10-01 | 2026-08-31 |
| A Study Investigating Intravenous Human Normal Immune Globulin (IGIV) 10% KIg10 (QIVIGY) in Subjects With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) Immune globulin (human) 10% solution for intravenous administration - Chronic Inflammatory Demyelinating Polyneuropathy | Phase 3 | Recruiting | Kedrion S.p.A. | 161 | 2026-10-01 | 2026-09-11 |
| Dronabinol and Epidiolex to Manage Uncontrolled Residual Symptoms of Buprenorphine Initiation Trial Dronabinol Capsules, Epidiolex 100 mg/mL Oral Solution, Placebo Dronabinol - Opioid Use Disorder | Phase 3 | Not yet recruiting | Montefiore Medical Center | 40 | 2026-10-01 | 2026-06-09 |
| Epidiolex Trial for Presymptomatic Treatment of Sturge-Weber Syndrome Epidiolex 100 mg/mL Oral Solution - Sturge - Weber Syndrome (SWS) | Phase 2 | Recruiting | Johns Hopkins University | 10 | 2026-09-17 | 2026-10-02 |
| Comparing Amla (Emblica Officinalis) and 3% Sodium Hypochlorite Against Enterococcus Faecalis in Root Canal Treatment. Sodium Hypochlorite 3% Solution, Emblica officinalis Solution - Pulp Necrosis, Apical Periodontitis | Not applicable | Not yet recruiting | Postgraduate Medical Institute, Lahore | 66 | 2026-09-17 | 2026-09-22 |
| A Study of Combogesic® IV (Intravenous) in Pediatric Patients With Acute Pain Combogesic® IV (fixed-dose combination containing acetaminophen 10 mg/ml + ibuprofen 3 mg/ml in 100 ml solution for infusion) - Acute Pain | Phase 3 | Recruiting | AFT Pharmaceuticals, Ltd. | 60 | 2026-09-14 | 2026-09-16 |
| A Single and Multiple Ascending Dose Trial Assessing Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ZP6590 in Participants With Normal Weight, Overweight and Obesity ZP6590, solution for injection, Placebo, solution for injection - Healthy Participants Study, Overweight and Obese Adults | Early Phase 1 | Recruiting | Zealand Pharma | 88 | 2026-07-09 | 2026-08-13 |
| UHFUS Characterization of Normal Lymphatic Anatomy Indocyanine green (ICG) solution injection, Ultra-High Frequency Ultrasound - Breast Cancer | Not applicable | Recruiting | University of California, Davis | 50 | 2026-06-17 | 2026-07-01 |
| Efficacy of Oral HA35 for Rapid Relief of Oral Pain and Pungent Sensation Capsaicin Oral Challenge, Allyl Isothiocyanate (AITC) Oral Challenge, 10% 35 kDa Hyaluronan (HA35) Oral Solution - Oral Pain, Oral Pungent Sensation | Not applicable | Completed | Nakhia Impex LLC | 30 | 2026-06-05 | 2026-09-10 |
| Sodium Bicarbonate for Critically Ill Patients With Metabolic Acidosis and Acute Kidney Injury Sodium Bicarbonate 8.4% Solution for Injection, Balanced crystalloid solution - Acute Kidney Injury, Metabolic Acidosis | Phase 4 | Recruiting | Universität Münster | 660 | 2026-05-07 | 2026-09-04 |
| VENEZE Peptide Factor Hair Serum Compared With Topical 2% Minoxidil for Androgenetic Alopecia Veneze peptide hair serum, Topical minoxidil - Androgenetic Alopecia (AGA) | Not applicable | Recruiting | Institute of Dermatology, Thailand | 80 | 2026-05-05 | 2026-05-13 |
| Effect of Intravenous Ketamine Combined With Spinal Anesthesia on Sensory Block Duration Compared to Spinal Anesthesia Alone in Lower Limb Surgeries in Geriatrics. Patients will receive 0.2 mg/kg IV of ketamine diluted to 5 ml followed by infusion 0.1 mg/kg/hr as a 20 ml solution, Patients will receive 5 ml of saline followed by infusion 0.1 ml/kg/hr as a 20 ml solution as a control group - IV Ketamine With Spinal Block | Not applicable | Recruiting | Cairo University | 61 | 2026-04-25 | 2026-04-30 |
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Alopecia (14) · Pain, Postoperative (11) · Obesity (10) · Primary Immunodeficiency Diseases (10) · Pain (9) · COVID-19 (7) · Keratosis, Actinic (7) · Ocular Hypertension (7) · Glaucoma, Open-Angle (6) · Neoplasms (5) · Onychomycosis (5) · Diabetes Mellitus (4) · Diabetes Mellitus, Type 1 (4) · Hypertension (4) · Infertility (4)
Boehringer Ingelheim (13) · GlaxoSmithKline (9) · Takeda (9) · Alcon Research (7) · Baxalta now part of Shire (6) · University Medical Centre Ljubljana (6) · Assiut University (5) · DUSA Pharmaceuticals, Inc. (5) · Allergan (4) · AstraZeneca (4) · Bayer (4) · Cairo University (4) · Pfizer (4) · Dompé Farmaceutici S.p.A (3) · Helsinki University Central Hospital (3)
United States (127) · Germany (31) · United Kingdom (27) · Spain (25) · Canada (24) · Egypt (23) · France (22) · Italy (19) · China (13) · Turkey (Türkiye) (12) · Belgium (11) · Switzerland (11) · Denmark (10) · Israel (10) · Poland (9)
Stuart Marcus, MD, PhD (5) · Alessandro Mazzetti, M.D. (2) · Andrej Janez, MD, PhD (2) · Eda Vrtacnik Bokal, professor (2) · Aaron Vinik, MD, PhD (1) · Abie Mendelsohn (1) · Ahmet B. Erdem (1) · Alessandro Villa, DDS, PhD, MPH (1)
PMID 26718625, PMID 38125671, PMID 10465169, PMID 10495374, PMID 10933492, PMID 11148177, PMID 11511857, PMID 11874817, PMID 1188424, PMID 12045122, PMID 12740257, PMID 12826636, PMID 15034503, PMID 15050036, PMID 15514282, PMID 15572968, PMID 15683545, PMID 17569567, PMID 17761356, PMID 18538406, PMID 18565211, PMID 18687132, PMID 19194156, PMID 19197072, PMID 19277688, PMID 19365194, PMID 19553648, PMID 19620039, PMID 19668532, PMID 19845686, PMID 20115946, PMID 20384750, PMID 20384751, PMID 20554319, PMID 20843247, PMID 21060150, PMID 21199096, PMID 21367592, PMID 21486454, PMID 21656179, PMID 21680942, PMID 21712909, PMID 21791473, PMID 21899919, PMID 22123804, PMID 22440736, PMID 22447964, PMID 22634722, PMID 22694845, PMID 22986417
2014 (5), 2019 (5), 2025 (5), 2016 (4), 2023 (4), 2017 (3), 2008 (2), 2015 (2), 2004 (1), 2005 (1), 2009 (1), R01AT011341 (1), R01CA276040 (1), R01DK142423 (1), R01DK149765 (1)