Lung Diseases: Clinical Trials

21270 completed, 6760 unknown, 4020 recruiting, 3189 terminated. 10139 Not applicable, 8717 Phase 2, 4990 Phase 1, 4408 Phase 3, 1934 Phase 4.

By phase and status

Phase	Trials	Status
Not applicable	10139	Completed 5507, Unknown 1797, Recruiting 1065, Terminated 537, Not yet recruiting 494, Withdrawn 326, Active not recruiting 313, Enrolling by invitation 67, Suspended 33
Phase 2	8717	Completed 4082, Unknown 1219, Terminated 1199, Recruiting 938, Withdrawn 460, Active not recruiting 439, Not yet recruiting 329, Suspended 32, Enrolling by invitation 19
Phase 1	4990	Completed 2593, Terminated 686, Recruiting 582, Unknown 464, Active not recruiting 290, Withdrawn 218, Not yet recruiting 126, Suspended 24, Enrolling by invitation 7
Phase 3	4408	Completed 2468, Unknown 568, Terminated 512, Recruiting 345, Active not recruiting 197, Withdrawn 191, Not yet recruiting 101, Suspended 16, Enrolling by invitation 10
Phase 4	1934	Completed 1145, Unknown 311, Terminated 183, Recruiting 111, Withdrawn 83, Not yet recruiting 52, Active not recruiting 38, Suspended 6, Enrolling by invitation 5
Early Phase 1	331	Completed 127, Unknown 71, Recruiting 38, Terminated 34, Not yet recruiting 20, Withdrawn 19, Active not recruiting 12, Enrolling by invitation 5, Suspended 5

Follow Lung Diseases: new trials by email Literature Review of Lung Diseases trials Research Report on Lung Diseases

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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Bubble CPAP Team-Based Care Strategy Feasibility Trial bCPAP team-based care strategy - Pneumonia in Children	Not applicable	Not yet recruiting	Yale University	95	2028-04-01	2026-06-02
PulmoSalud: Multimodal Program for Prehabilitation and Early Home Rehabilitation in Patients With Lung Cancer Individualized pre-operative physical exercise, Post-operative rehabilitation physical exercise, Respiratory physiotherapy Prehabilitation - Lung Cancer	Not applicable	Not yet recruiting	FranciscoVeraSerrano	84	2028-01-01	2026-03-17
Chronic COUGH Management in Interstitial Lung DisEase Non-pharmacological cough control therapy, Healthy lifestyle - Interstitial Lung Disease, Chronic Cough	Not applicable	Not yet recruiting	Aveiro University	60	2027-12-20	2025-01-20
A Study of RC48-ADC Combined With Pyrotinib For Treatment of Local Advanced or Metastasis NSCLC With HER2 Mutation RC48-ADC, Pyrotinib - Non-small Cell Lung Cancer	Phase 1 / Phase 2	Not yet recruiting	RemeGen Co., Ltd.	26	2027-12-01	2026-09-22
Symptom Management to Improve Completion of Patient-reported Outcome Measures Monitoring of PROMIS symptoms and physical function, Monitoring of additional symptoms and symptom self-management - Malignant Solid Neoplasm, Malignant Head and Neck Neoplasm	Not applicable	Not yet recruiting	Henry Ford Health System	78	2027-10-01	2026-07-29
Developing an Intervention to Optimize Virtual Care Adoption for COPD Management VC-OPTIONS - Chronic Obstructive Pulmonary Disease	Not applicable	Not yet recruiting	VA Office of Research and Development	40	2027-09-02	2026-09-29
A Multiple Dose Study to Investigate Safety, Tolerability and Pharmacokinetics of MN-08 Tablets MN-08 24 mg/day, MN-08 60 mg/day - Pulmonary Arterial Hypertension	Phase 1	Not yet recruiting	Guangzhou Magpie Pharmaceuticals Co., Ltd.	16	2027-09-01	2026-09-14
Remote Intervention Versus Routine Monitoring in COPD Patients With Chronic Hypercapnia Receiving Home Non-invasive Respiratory Support Remote Management, Remote Monitoring Only - COPD (Chronic Obstructive Pulmonary Disease), Acute Exacerbation of COPD	Not applicable	Not yet recruiting	Sir Run Run Shaw Hospital	236	2027-08-01	2026-08-06
Perceptions of Undergraduate Students and Teaching Staff on Online Teaching Questionnaire - Covid19		Suspended	Misr International University	9209	2027-07-15	2026-10-08
RSV Vaccination to Reduce Recurrent AECOPD RSV vaccination (Arexvy, GlaxoSmithKline) - COPD, RSV	Phase 4	Not yet recruiting	Chinese University of Hong Kong	320	2027-07-01	2026-04-13
cfMSC Stem Cell Therapy Targeting COPD clonal fetal MSCs - Chronic Obstructive Pulmonary Disease (COPD)	Phase 1 / Phase 2	Not yet recruiting	Shenzhen Geno-Immune Medical Institute	30	2027-06-30	2026-11-02
A Master Trial Assessing the Technical Feasibility of First-In-Human Real-Time Image Guided Radiation Therapy Methods Real-Time Image Guided Radio Therapy (IGRT) - Cancer	Not applicable	Not yet recruiting	University of Sydney	40	2027-06-01	2026-05-20
Antigen-specific T Cells Against Lung Cancer Lung cancer-specific T cells - Lung Cancer	Phase 1 / Phase 2	Not yet recruiting	Shenzhen Geno-Immune Medical Institute	20	2027-06-01	2026-11-02
Pivotal Study to Assess Safety and Performance of Neola®, a Novel Lung Monitoring Device for Neonates Lung monitoring with the Neola device - RDS of Prematurity, Preterm Birth	Not applicable	Not yet recruiting	Neola Medical Inc	22	2027-06-01	2026-11-12
Trial of a Personalized and Adaptive Neoantigen Dose-Adjusted Vaccine Concurrently With Pembrolizumab PANDA-VAC, Pembrolizumab - Squamous Cell Lung Cancer, Squamous Non-small Cell Lung Cancer	Phase 1	Suspended	UNC Lineberger Comprehensive Cancer Center	6	2027-05-20	2026-04-23
Multicentric, Randomized Study to Assess Safety and Efficacy of Centhaquine in Patients With ARDS Normal Saline, Centhaquine - Acute Respiratory Distress Syndrome (ARDS)	Phase 2	Not yet recruiting	Pharmazz, Inc.	80	2027-05-01	2026-09-17
Clinical Trial of 2-HOBA in Pulmonary Arterial Hypertension 2-HOBA - Pulmonary Arterial Hypertension	Phase 2	Not yet recruiting	Vanderbilt University Medical Center	12	2027-05-01	2026-11-10
Multinational Observational Study to Describe Diagnostic Stage Shift in Patients With Lung Cancer Using Medical Records Lung Cancer		Not yet recruiting	AstraZeneca	3000	2027-04-01	2026-06-02
Echinocandin Added to Standard Treatment for Severe Pneumocystis Pneumonia Echinocandins, Placebo (0.9% Sodium chloride) infusion - Pneumocystis Jirovecii Pneumonia	Phase 3	Not yet recruiting	McGill University Health Centre/Research Institute of the McGill University Health Centre	416	2027-04-01	2026-11-05
A Phase 1a/1b Of Zanidatamab In Combination With Zongertinib In HER2-Mutated Non-Small Cell Lung Cancer (NSCLC) Zanidatamab, Zongertinib - Non Small Cell Lung Cancer	Phase 1	Not yet recruiting	M.D. Anderson Cancer Center	24	2027-04-01	2026-10-28

Showing 20 of 40103. Sign in to see all of them.

Narrower conditions

COVID-19 (7575)  ·  Carcinoma, Non-Small-Cell Lung (7102)  ·  Pulmonary Disease, Chronic Obstructive (5343)  ·  Lung Neoplasms (5276)  ·  Asthma (4474)  ·  Cystic Fibrosis (1584)  ·  Pneumonia (1393)  ·  Respiratory Distress Syndrome (1345)  ·  Small Cell Lung Carcinoma (1207)  ·  Hypertension, Pulmonary (1019)  ·  Neoplasms (1001)  ·  Breast Neoplasms (918)  ·  Coronavirus Infections (828)  ·  Pulmonary Embolism (783)

Broader conditions

Respiratory Tract Diseases (39830)  ·  Neoplasms by Site (11798)  ·  Respiratory Tract Neoplasms (11605)  ·  Thoracic Neoplasms (11579)  ·  Pathological Conditions, Signs and Symptoms (11335)  ·  Infections (11326)  ·  Neoplasms (11271)  ·  Respiratory Tract Infections (10741)  ·  Lung Diseases, Obstructive (10389)  ·  Pathologic Processes (9846)  ·  Pneumonia (8529)  ·  Virus Diseases (8326)  ·  RNA Virus Infections (8265)  ·  Nidovirales Infections (8003)

Interventions

Carboplatin (1066)  ·  Cisplatin (794)  ·  Pemetrexed (743)  ·  pembrolizumab (584)  ·  Paclitaxel (571)  ·  Docetaxel (496)  ·  Gemcitabine (396)  ·  Blood Specimen Collection (384)  ·  Radiotherapy (382)  ·  Standard of Care (368)  ·  Erlotinib Hydrochloride (334)  ·  Nivolumab (321)  ·  Bevacizumab (284)  ·  Tiotropium Bromide (275)  ·  Etoposide (266)

Sponsors

AstraZeneca (826)  ·  GlaxoSmithKline (658)  ·  Boehringer Ingelheim (462)  ·  Assistance Publique - Hôpitaux de Paris (391)  ·  Novartis Pharmaceuticals (341)  ·  National Cancer Institute (NCI) (335)  ·  Pfizer (319)  ·  Assiut University (237)  ·  M.D. Anderson Cancer Center (228)  ·  National Heart, Lung, and Blood Institute (NHLBI) (202)  ·  National Institute of Allergy and Infectious Diseases (NIAID) (193)  ·  Eli Lilly and Company (180)  ·  Merck Sharp & Dohme LLC (175)  ·  Mayo Clinic (170)  ·  Memorial Sloan Kettering Cancer Center (170)

Countries

United States (13079)  ·  China (4528)  ·  France (3906)  ·  United Kingdom (3055)  ·  Canada (2818)  ·  Germany (2663)  ·  Spain (2542)  ·  Italy (2405)  ·  Turkey (Türkiye) (1556)  ·  Belgium (1523)  ·  South Korea (1498)  ·  Netherlands (1483)  ·  Australia (1376)  ·  Poland (1308)  ·  Brazil (1172)

Results publications

PMID 34473343, PMID 36472162, PMID 37983082, PMID 33331662, PMID 35244208, PMID 33511633, PMID 35713300, PMID 31986264, PMID 32031570, PMID 32109013, PMID 32171076, PMID 32091533, PMID 33502773, PMID 34013969, PMID 36734509, PMID 37162745, PMID 27881132, PMID 36695483, PMID 37489818, PMID 37591523, PMID 26903337, PMID 34495549, PMID 34658014, PMID 35688625, PMID 37010196, PMID 32167524, PMID 32943047, PMID 23688302, PMID 35815359, PMID 42149813, PMID 34350582, PMID 37542951, PMID 39393433, PMID 10793162, PMID 12091180, PMID 22797452, PMID 25693014, PMID 31319851, PMID 31401903, PMID 32192578, PMID 29400693, PMID 32007143, PMID 32142651, PMID 32250385, PMID 33305842, PMID 33337539, PMID 33735508, PMID 35691614, PMID 37319354, PMID 38597249

NIH funding

2023 (269), 2018 (161), 2017 (153), 2015 (146), 2016 (143), 2019 (132), 2025 (130), 2014 (114), 2009 (92), 2008 (68), U10CA031946 (50), P30CA033572 (38), U10CA032102 (36), P30CA012197 (27), U10CA180888 (25)