103 completed, 53 unknown, 27 recruiting, 13 terminated. 116 Not applicable, 25 Phase 2, 23 Phase 3, 15 Phase 4, 7 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Appendectomy as an Adjunct Procedure in Endometriosis Surgery Appendectomy, Standard of Care (SOC) - Endometriosis | Not applicable | Not yet recruiting | Mount Sinai Hospital, Canada | 240 | 2027-04-01 | 2026-09-16 |
| Quicksilver II Pilot Study Direct-to-surgery (i.e., no neoadjuvant chemotherapy), Control Group - Stage II Rectal Cancer, Stage III Rectal Cancer | Not applicable | Not yet recruiting | Mount Sinai Hospital, Canada | 18 | 2026-09-01 | 2026-07-07 |
| Mechanical Bowel Prep Randomized Study IVA+OA versus IVA+MBP+OA - Colorectal Surgery | Not applicable | Not yet recruiting | Mount Sinai Hospital, Canada | 1062 | 2026-09-01 | 2026-06-22 |
| Post-operative Cognitive Decline After Ambulatory Cataract Surgery in the Elderly Population Post-Operative Cognitive Decline in Older Adults, Post-operative Cognitive Decline | Not yet recruiting | Samuel Lunenfeld Research Institute, Mount Sinai Hospital | 300 | 2026-08-01 | 2026-08-26 | |
| 2.5% Lidocaine/2.5% Prilocaine Cream for IUD Insertion and Endometrial Biopsy 2.5% lidocaine/2.5% prilocaine topical cream, VersaPro Cream Base for Compounding - IUD, Endometrial Biopsy | Not applicable | Not yet recruiting | Mount Sinai Hospital, Canada | 174 | 2026-07-30 | 2026-08-17 |
| Use of Dexmedetomidine to Improve Pain Control and Recovery After Laparocopic-Assisted Bowel Surgery in Adults Dexmedetomidine infusion, Postoperative matched placebo of 0.9% saline infusion - Bowel Diseases, Inflammatory, Bowel Surgery | Phase 3 | Not yet recruiting | Dr. Naveed Siddiqui | 70 | 2026-07-01 | 2026-06-24 |
| Optimizing Anticoagulation in Pregnancies With Mechanical Heart Valves LMWH and LDA, Vitamin K antagonists (e.g warfarin)+/- LDA, Sequential therapy +/- LDA - Pregnancy, Prosthetic Heart Valve | Not applicable | Recruiting | Mount Sinai Hospital, Canada | 100 | 2026-05-26 | 2026-06-22 |
| Stiffness and Low Dose Irradiation RCT Low-Dose External Beam Irradiation, Hinged Revision Total Knee Arthroplasty - Arthrofibrosis of Knee | Not applicable | Recruiting | Mount Sinai Hospital, Canada | 36 | 2026-04-01 | 2026-08-17 |
| Time Restricted-EAting for Type 2 Diabetes and MEtabolic Health: the TEA TIME Trial Time-restricted eating, Standard lifestyle - Type 2 Diabetes, Overweight (BMI > 25) | Not applicable | Recruiting | Mount Sinai Hospital, Canada | 112 | 2026-02-01 | 2026-02-11 |
| Impact of Semaglutide Withdrawal on Cardiometabolic Profile and Physiology of Energy Balance: Recovery Effects After Semaglutide Termination Gradual dose reduction of semaglutide, Abrupt cessation of semaglutide - Obesity (Disorder), Weight Change | Phase 3 | Recruiting | Mount Sinai Hospital, Canada | 98 | 2026-02-01 | 2026-02-11 |
| The Pregnancy and Postpartum Mental Health Optimization Virtual Intervention Network Enhanced Usual Care, MOVIN Care Platform - Depression, Postpartum | Not applicable | Recruiting | Women's College Hospital | 570 | 2025-10-29 | 2026-10-13 |
| pDIFFIR: Geriatric Periprosthetic DIstal Femur: FIxation Versus Replacement Distal Femur Replacement, Surgical fixation - Distal Femur Fracture, Periprosthetic Fracture Around Prosthetic Joint Implant Knee | Not applicable | Recruiting | Unity Health Toronto | 148 | 2025-10-17 | 2025-12-18 |
| Presacral Nerve Block Versus Sham Block on Post-operative Pain for Total Laparoscopic Hysterectomy Ropivacaine injection, Normal saline injection - Post-operative Pain | Phase 2 | Recruiting | Mount Sinai Hospital, Canada | 60 | 2025-09-24 | 2026-04-06 |
| Optic Nerve Sheath Ultrasound in Giant Cell Arteritis Optic nerve sheath ultrasound, Standardized GCA assessment - Giant Cell Arteritis, Anterior Ischemic Optic Neuropathy | Recruiting | Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal | 285 | 2025-08-09 | 2026-10-21 | |
| Methoxyflurane for IUD Insertion and Endometrial Biopsy Methoxyflurane - Penthrox, Placebo Penthrox inhaler - Endometrial Biopsy, Intrauterine Devices | Not applicable | Recruiting | Mount Sinai Hospital, Canada | 174 | 2025-07-24 | 2025-07-30 |
| Low Versus Standard Pressure Pneumoperitoneum on Shoulder Tip Pain Low Pressure Penumoperitoneum, Standard Pressure Group (No intervention- active comparator) - Surgery, Laparoscopic | Not applicable | Recruiting | Mount Sinai Hospital, Canada | 82 | 2025-07-02 | 2025-07-31 |
| Fetoscopic Robotic Open Spina Bifida Treatment Fetoscopic robotic open spina bifida closure - Fetal Congenital Abnormalities, Fetoscopy | Not applicable | Not yet recruiting | Mount Sinai Hospital, Canada | 15 | 2025-07-01 | 2025-05-07 |
| 1% Lidocaine Paracervical Block for Endometrial Biopsy Lidocaine 1% Injectable Solution, Capped needle - Endometrial Biopsy | Not applicable | Completed | Mount Sinai Hospital, Canada | 96 | 2025-06-19 | 2026-01-27 |
| Evaluating the Use of Educational Videos in Newly Diagnosed Patients in a Medical Oncology Sarcoma Clinic Educational videos, Standard of Care - Sarcoma | Not applicable | Recruiting | Mount Sinai Hospital, Canada | 100 | 2025-05-05 | 2026-10-14 |
| The Use of Virtual Reality Technology During Oocyte Retrieval for in Vitro Fertilization VR-based intervention (VRReliever Software V0.3.4 fromXRHealth), VR headset without any scenery - Oocyte Retrieval, Adverse Events | Not applicable | Not yet recruiting | Mount Sinai Hospital, Canada | 50 | 2025-01-15 | 2024-12-18 |
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Diabetes Mellitus, Type 2 (14) · Premature Birth (13) · Colitis, Ulcerative (12) · Depression (12) · Crohn Disease (9) · Inflammatory Bowel Diseases (9) · Anxiety Disorders (8) · Pain (7) · Diabetes Mellitus (6) · Influenza, Human (6) · Sarcoma (6) · Chronic Disease (5) · Dementia (5) · Heart Failure (5) · Pain, Postoperative (5)
Saline Solution (6) · Standard of Care (5) · Metformin (4) · Heparin, Low-Molecular-Weight (3) · Influenza Vaccines (3) · Tranexamic Acid (3) · Aspirin (2) · Blood Specimen Collection (2) · Botulinum Toxins, Type A (2) · Cholecalciferol (2) · Chorionic Gonadotropin (2) · Hydromorphone (2) · Ibuprofen (2) · Letrozole (2) · Liraglutide (2)
Canada (201) · United States (19) · United Kingdom (6) · Italy (5) · Spain (5) · Australia (4) · Belgium (4) · France (4) · Ireland (4) · Germany (3) · Israel (2) · Poland (2) · Austria (1) · China (1) · Hong Kong (1)
Ravi Retnakaran, MD (5) · Denice Feig, MD (4) · Keith Jarvi, MD (4) · Adel Mohamed, MD (3) · Allison J McGeer, MD (3) · Robert F Casper, MD (3) · Abhimanyu Sud, MD (2) · Allan Gordon, MD (2) · Amir Khoshbin, MD (2) · Azar Azad, PhD (2) · Carolyn Steele Gray, PhD (2) · Catherine Varner, MD MSc (2) · Danny Lovatsis, MD (2) · Erin Kennedy (2) · Geoffrey C Nguyen, MD, PhD (2)
PMID 40243391, PMID 34808130, PMID 35032132, PMID 15132746, PMID 15842354, PMID 17326946, PMID 18343253, PMID 18552687, PMID 19878532, PMID 20626619, PMID 22258545, PMID 22475409, PMID 22802929, PMID 22902784, PMID 23180503, PMID 24129396, PMID 24550219, PMID 25234606, PMID 25249651, PMID 25386678, PMID 25414155, PMID 25466317, PMID 25495067, PMID 25849721, PMID 25873050, PMID 26079776, PMID 26170014, PMID 26181221, PMID 26230296, PMID 26299215, PMID 26489482, PMID 26671340, PMID 27430714, PMID 27433335, PMID 27435163, PMID 27480314, PMID 27488380, PMID 27547422, PMID 27660596, PMID 27684415, PMID 27965866, PMID 28363933, PMID 28472325, PMID 28487349, PMID 28719693, PMID 28720558, PMID 28838362, PMID 28923465, PMID 29544550, PMID 29564507
U01DK062423 (2), R01HD111018 (1)