719 completed, 228 unknown, 160 recruiting, 76 not yet recruiting. 673 Not applicable, 127 Phase 2, 91 Phase 1, 55 Phase 3, 47 Phase 4.
Follow Hypoxia: new trials by email Literature Review of Hypoxia trials Research Report on Hypoxia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Impact of Iron Supplementation on Right Ventricular Function and Exercise Performance in Hypoxia Ferrous sulfate 325mg - Right Ventricular Dysfunction, Hypoxia | Early Phase 1 | Not yet recruiting | University of Colorado, Denver | 5 | 2028-03-01 | 2026-04-29 |
| Multicentric, Randomized Study to Assess Safety and Efficacy of Centhaquine in Patients With ARDS Normal Saline, Centhaquine - Acute Respiratory Distress Syndrome (ARDS) | Phase 2 | Not yet recruiting | Pharmazz, Inc. | 80 | 2027-05-01 | 2026-09-17 |
| Intranasal Stem Cells to Treat Perinatal Brain Injury to Combat Cerebral Palsy MSC, marrow, Placebo - Perinatal Arterial Ischemic Stroke, Perinatal Asphyxia | Phase 2 / Phase 3 | Not yet recruiting | UMC Utrecht | 162 | 2027-04-01 | 2026-09-21 |
| Cell-Based Therapy for White Matter Repair in Periventricular Leukomalacia Investigational Combination Product - Periventricular Leukomalacia, White Matter Disease | Early Phase 1 | Withdrawn | MGAM LLC | 2027-01-01 | 2025-07-22 | |
| Spectroscopic Assessment of Tissue Oxygenation Changes in Plastic Surgical Flap Reconstructions Flap Ischemia, Hypoxia | Not yet recruiting | Spectrocor | 30 | 2026-12-01 | 2026-08-26 | |
| Bedside Cranial Ultrasound for Risk-Stratified Imaging in Pediatric Acute Brain Injury Acute Brain Injury, Traumatic Brain Injury | Not yet recruiting | Virginia Commonwealth University | 220 | 2026-11-30 | 2026-08-19 | |
| Supraglottic Oxygenation Via Oral Transtracheal Catheter for Reducing the Incidence of Hypoxemia During ERCP Under Sedation The Supraglottic Oxygenation Via Oral Transtracheal Catheter Group, The Regular Nasal Cannula - Choledocholithiasis With Cholecystitis With Obstruction, Obstructive Jaundice | Not applicable | Not yet recruiting | Zhejiang University | 410 | 2026-11-12 | 2026-09-25 |
| Effect of High-flow Nasal Cannula Oxygenation on the Incidence of Hypoxemia During Painless Gastrointestinal Endoscopy in Patients at High Risk for Obstructive Sleep Apnea Syndrome in High-altitude Regions High-flow nasal cannula Group, Regular Nasal Cannula Group - Hypoxemia, Gastric Cancer (Diagnosis) | Not applicable | Not yet recruiting | Diansan Su | 430 | 2026-11-02 | 2026-10-29 |
| Reminder-enhanced Incentive Spirometry Evaluation Alarms ON - Hypoxemia | Not applicable | Not yet recruiting | University of Colorado, Denver | 88 | 2026-11-01 | 2026-08-31 |
| Methodological Study of Exercise and Hypoxic Conditions in Healthy Subjects Exercise and hypoxia - Healthy Subjects (HS), Exercise | Not applicable | Recruiting | University Hospital, Grenoble | 305 | 2026-10-19 | 2026-10-23 |
| The PROTECT-HIE Pilot Trial Dobutamine, TnECHO - Hypoxic-ischemic Encephalopathy (HIE) | Phase 2 | Recruiting | University of Alberta | 40 | 2026-10-13 | 2026-10-20 |
| BMI-Adjusted PEEP During One-Lung Ventilation in Thoracic Surgery Fixed PEEP, BMI-adjusted PEEP - Pulmonary Resection Surgery, One Lung Ventillation (OLV) | Not applicable | Recruiting | Jesús Manuel Nieves Alonso | 150 | 2026-10-07 | 2026-10-09 |
| Ventilator Pressure and Optimization of Compliance and Hemodynamics Increase in the PEEP followed by decrease in the PEEP, Decrease in the PEEP followed by increase in the PEEP - Bronchopulmonary Dysplasia, Pulmonary Hypertension Due to Lung Diseases and Hypoxia | Not applicable | Recruiting | University of Alabama at Birmingham | 24 | 2026-10-01 | 2026-10-26 |
| Neuro-MoD: Neuroplasticity With Motor Development Constraint-Induced Movement Therapy (CIMT), Transcutaneous auricular vagus nerve stimulation (taVNS) - Perinatal Brain Injury | Not applicable | Recruiting | University of Wisconsin, Madison | 8 | 2026-10-01 | 2026-10-19 |
| Evaluation of Neonatal Acute Hypoxia at Delivery Using Fetal Physiology and Eucapnic pH Assessment Neonatal Acidemia and Hypoxia | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 1000 | 2026-10-01 | 2026-09-02 | |
| Sildenafil Plus Hypothermia to Treat Neonatal Encephalopathy Sildenafil Citrate (IV) - Hypoxic-Ischemic Encephalopathy | Phase 2 | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 24 | 2026-10-01 | 2026-03-31 |
| Gemini Flash 3.6 Versus Human Observers for FIGO-Based Interpretation of Intrapartum Cardiotocography Fetal Hypoxia, Fetal Distress | Not yet recruiting | Assiut University | 415 | 2026-10-01 | 2026-09-18 | |
| Impact of Closed PBSC Collection With Reduced Gas-Phase Oxygen Exposure on Graft Quality and Early Engraftment in Allo-HSCT Closed PBSC collection with reduced gas-phase oxygen exposure - Allogeneic Hematopoietic Stem Cell Transplantation (HSCT), Oxygen Deficiency | Not applicable | Not yet recruiting | Institute of Hematology & Blood Diseases Hospital, China | 240 | 2026-10-01 | 2026-10-29 |
| Assessment of Total Pulmonary Resistance sPAP/CO Between High Altitude HA vs. Sea Level LA in Patients With Pulmonary Arterial Hypertension PAH Descent from 2850m to sea level - Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease | Not applicable | Not yet recruiting | Silvia Ulrich Somaini | 20 | 2026-09-25 | 2026-09-04 |
| Assessment of Six-minute Walking Distance Between Sea Level LA vs. High Altitude HA After Re-ascent in Patients With Pulmonary Arterial Hypertension PAH Re-Ascent sea level to 2850m - Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease | Not applicable | Not yet recruiting | Silvia Ulrich Somaini | 20 | 2026-09-25 | 2026-09-01 |
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Hypoxia-Ischemia, Brain (244) · Hypoxia, Brain (81) · Altitude Sickness (63) · Respiratory Insufficiency (59) · Hypercapnia (48) · Motor Activity (45) · COVID-19 (40) · Hyperoxia (39) · Brain Injuries (37) · Hypertension, Pulmonary (37) · Pulmonary Disease, Chronic Obstructive (37) · Stroke (36) · Heart Arrest (34) · Pneumonia (34)
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Oxygen (23) · Saline Solution (16) · Blood Specimen Collection (15) · Propofol (15) · Acetazolamide (12) · Sodium Chloride (12) · Continuous Positive Airway Pressure (11) · Hypothermia, Induced (10) · Exercise (9) · Noninvasive Ventilation (8) · Umbilical Cord Clamping (8) · Insemination, Artificial, Homologous (7) · Magnetic Resonance Imaging (7) · Standard of Care (7) · 3-fluoro-2-(4-((2-nitro-1H-imidazol-1-yl)methyl)-1H-1,2,3-triazol-1-yl)propan-1-ol (6)
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PMID 24524452, PMID 35835616, PMID 21304242, PMID 21876461, PMID 22224835, PMID 22883447, PMID 26903337, PMID 27567470, PMID 28791567, PMID 28852473, PMID 28901969, PMID 30536725, PMID 32071135, PMID 32813884, PMID 32815872, PMID 33933271, PMID 34837553, PMID 38683158, PMID 38941098, PMID 39885431, PMID 40829895, PMID 41250198, PMID 41921908, PMID 10211806, PMID 10492412, PMID 10545552, PMID 10675427, PMID 10685584, PMID 10763759, PMID 10781266, PMID 10793162, PMID 10793602, PMID 10869046, PMID 11015501, PMID 11103187, PMID 11465176, PMID 11575407, PMID 11703564, PMID 11891439, PMID 12165594, PMID 12502975, PMID 12651052, PMID 12717123, PMID 13326155, PMID 1356374, PMID 14569423, PMID 14977901, PMID 15199405, PMID 15269312, PMID 15385385
2017 (4), U10HD021364 (4), U10HD021373 (4), U10HD021385 (4), U10HD027851 (4), U10HD027853 (4), U10HD027856 (4), U10HD027880 (4), U10HD027904 (4), U10HD034216 (4), U10HD040492 (4), U10HD040689 (4), 2019 (3), U10HD027871 (3), U10HD036790 (3)