174 completed, 36 unknown, 27 terminated, 21 recruiting. 157 Not applicable, 44 Phase 4, 26 Phase 2, 23 Phase 3, 11 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dialysis Less Frequently in the Elderly Twice weekly hemodialysis, Thrice weekly hemodialysis treatment - Hemodialysis, End Stage Kidney Disease (ESKD) | Not applicable | Not yet recruiting | Queen's University | 210 | 2026-10-01 | 2026-07-31 |
| Effect of Patient Anxiety Level Prior to Undergoing ERCP and Procedure Tolerability and Outcomes. Not applicable- observational study - Anxiety, Biliary and Pancreatic Diseases | Not yet recruiting | Mandip Rai | 200 | 2026-08-01 | 2026-07-13 | |
| Identifying Biomarkers of Response to Digital Interventions for Mood Disorders Online Cognitive Behavioural Therapy - Depression / Major Depressive Disorder, Bipolar Disorder (BD) | Not applicable | Enrolling by invitation | Centre for Addiction and Mental Health | 200 | 2026-07-28 | 2026-08-27 |
| The Effects of LEUVATE on Glycemia, Insulinemia, Aminoacidemia, and Protein Synthesis in GLP-1 RA-treated Adults GLP-1 - The Whole-body Protein Synthesis Response to Protein With Amino Acid or Amino Acids | Not applicable | Not yet recruiting | Nutraceutical Innovations LLC | 8 | 2026-06-01 | 2026-05-20 |
| Prehabilitation Before Major Surgery Virtually Monitored Home-Based Prehabilitation Program - Prehabilitation, Preoperative Care | Not applicable | Not yet recruiting | Queen's University | 120 | 2026-06-01 | 2026-05-15 |
| Developing a Colonoscopy Preparation Protocol for Patients With Diabetes timing of cleansing and procedure - Hypoglycaemia, Diabete Mellitus | Not applicable | Not yet recruiting | Queen's University | 40 | 2026-06-01 | 2026-04-24 |
| Evaluating the Feasibility of Prehabilitation Delivery Models for Patients Preparing for Ovarian Cancer Surgery Multimodal Prehabilitation Program, Educational Materials - Prehabilitation, Preoperative Aerobic Training | Not applicable | Not yet recruiting | Jordan Leitch | 36 | 2026-05-14 | 2026-05-27 |
| Caffeine for Infants Born at 28 to 34 Weeks Receiving Respiratory Support Caffeine, Placebo - Preterm Birth, Caffeine | Phase 2 | Not yet recruiting | Queen's University | 62 | 2026-04-01 | 2026-03-10 |
| Using Music During Wound Care Among Seniors With Pressure Injuries Music listening - Pressure Injuries, Pressure Injury | Not applicable | Not yet recruiting | McMaster University | 50 | 2026-04-01 | 2026-03-06 |
| Does a Virtual Program for Pelvic Pain Improve Pain and Sexual Outcomes in Individuals With Provoked Vestibulodynia? Virtual online pelvic health program - Vulvodynia (Chronic Vulvar Pain), Vulvar Vestibulitis | Not applicable | Recruiting | Queen's University | 250 | 2025-12-17 | 2026-02-12 |
| Accelerating Adoption of Patient-centered Cervical Cancer Screening and Treatment Linkage in Kenya DADA LINK - Cervical Cancer, Cervical Cancer Screening | Not applicable | Recruiting | Kenyatta National Hospital | 1980 | 2025-12-01 | 2026-01-12 |
| Supporting Re-engagement in Life: Coaching to Enhance Participation in Valued Activities Following Stroke Occupational Performance Coaching (OPC), computer cognitive training program (CogniFit) - Stroke | Not applicable | Recruiting | Queen's University | 118 | 2025-11-10 | 2026-08-12 |
| A Probiotic Based Intervention in Pregnancies Complicated by GDM 5-strain probiotic plus prebiotic natural health product, Placebo - Gestational Diabetes Mellitus (GDM), Microbiome, Human | Phase 2 | Not yet recruiting | Queen's University | 173 | 2025-10-01 | 2025-06-06 |
| Human Skeletal Muscle Response to 5 Days of Bedrest in Young Adults Bedrest - Muscular Atrophy, Insulin Resistance | Not applicable | Recruiting | Queen's University | 12 | 2025-09-01 | 2025-09-22 |
| Bone Enhanced Ultrasound (BEUS) Data Library Development Project spinal ultrasound - Lower Back Pain, Facet Joint Pain; Low Back Pain | Not yet recruiting | Queen's University | 100 | 2025-09-01 | 2025-07-29 | |
| A Tumor Immune Biomarker Guided Approach for Improving Response to BCG in Patients With High-risk NMIBC. Gemcitabine + BCG, BCG (TICE strain) - NMIBC, Non-Muscle Invasive Bladder Urothelial Carcinoma | Phase 1 / Phase 2 | Not yet recruiting | Queen's University | 31 | 2025-08-01 | 2025-07-17 |
| Therapeutic Improvement in People With Schizophrenia Undergoing tACS/CBTp (Transcranial Alternating Current Stimulation Applied Pre-cognitive Behavioral Therapy for Psychosis) Associated to Usual Medication Regimen Experimental: tASC/CBTp: gamma band electric stimulation for 20 minutes at the beginning of the CBTp session, Sham Comparator - Schizophrenia, Schizoaffective Disorder | Not applicable | Not yet recruiting | Felicia Iftene | 28 | 2025-07-24 | 2025-07-24 |
| FIT-ATOMIC Exercise Feasibility Trial Exercise Training, Mobility and Flexibility Training - Neuroinflammatory Diseases, Multiple Sclerosis | Not applicable | Unknown | The Hospital for Sick Children | 40 | 2025-06-01 | 2025-05-21 |
| Early Genomic Testing for Inherited Bleeding Disorders Genetic testing for inherited bleeding disorders - Bleeding Disorder | Early Phase 1 | Recruiting | Queen's University | 212 | 2025-05-31 | 2025-07-31 |
| Allergenic Extract Standardized Cat Hair AP in an Allergic Rhinitis Model. Allergenic Extract Standardized Cat Hair Acetone-Precipitated (AP) - Allergic Rhinitis | Not applicable | Active not recruiting | Queen's University | 20 | 2025-03-04 | 2026-01-20 |
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Motor Activity (24) · Depressive Disorder, Major (17) · Depression (16) · Pulmonary Disease, Chronic Obstructive (15) · Dyspnea (9) · Obesity (9) · Psychotic Disorders (9) · Anxiety Disorders (7) · Bipolar Disorder (6) · Multiple Sclerosis (6) · Osteoarthritis, Knee (6) · Schizophrenia (6) · Chronic Pain (5) · Critical Illness (5) · Dementia (5)
Exercise (7) · Escitalopram (6) · Dexetimide (5) · Cognitive Behavioral Therapy (4) · Atorvastatin (3) · Cognitive Remediation (3) · Ketamine (3) · Ketorolac Tromethamine (3) · Lidocaine (3) · Pico-Salax (3) · Sodium Chloride (3) · Transcranial Magnetic Stimulation (3) · Acetaminophen (2) · Albuterol, Ipratropium Drug Combination (2) · Bisacodyl (2)
Canada (262) · United States (8) · Belgium (3) · Bulgaria (3) · Tanzania (3) · Ireland (2) · Kenya (2) · Brazil (1) · China (1) · Germany (1) · Turkey (Türkiye) (1) · United Kingdom (1)
Lawrence Hookey, MD (10) · Denis E O'Donnell, MD, FRCPC (8) · Daren K Heyland, MD (4) · Denis E O'Donnell, MD (4) · Jordan Miller, PhD (4) · Lawrence Hookey (4) · Robert Ross, PhD (4) · Roumen Milev, MD (4) · Anne K Ellis, MD (3) · Christopher Bowie, PhD (3) · Dallas P Seitz, MD (3) · Karen Yeates, MD (3) · Nauzer Forbes, MD MSc (3) · Roumen V. Milev, MD (3) · Sherif El-Defrawy, MD PhD FRCSC (3)
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U01DK063788 (1), U54CA284036 (1)