2416 completed, 690 unknown, 347 recruiting, 248 not yet recruiting. 2322 Not applicable, 272 Phase 2, 254 Phase 4, 202 Phase 3, 108 Phase 1.
Follow Periodontal Diseases: new trials by email Literature Review of Periodontal Diseases trials Research Report on Periodontal Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dimensional Changes: Randomized Clinical Trial Gum Graft Placed on Denuded Bone, Gum Graft Placed on Split Thickness Periosteal Bed Preparation - Gingival Recession | Not applicable | Not yet recruiting | University of Iowa | 50 | 2028-08-01 | 2026-09-09 |
| Autogenous Mesenchymal Stem Cell Culture-Derived Signalling Molecules as Enhancers of Bone Formation in Bone Grafting Maxillary sinus floor elevation grafting with synthetic bone substitute. - Bone Loss, Osteoclastic, Bone Loss, Alveolar | Phase 1 | Not yet recruiting | Pontificia Universidade Católica do Rio Grande do Sul | 20 | 2027-12-15 | 2026-09-21 |
| Efficacy of Different Disinfection Technologies in Molar Non-Surgical Retreatment GentleWave System, Conventional rotary instrumentation with passive ultrasonic irrigation - Apical Periodontitis | Not applicable | Not yet recruiting | University of Alabama at Birmingham | 60 | 2027-07-01 | 2026-04-08 |
| Education-Based Oral Health Promotion Intervention During Pregnancy: Implementation Protocol in Bangladesh Integrated Oral Health Promotion Package (IOHPP) - Pregnancy, Periodontal Diseases | Not applicable | Not yet recruiting | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | 688 | 2027-06-01 | 2026-10-21 |
| Effectiveness of Interactive Techniques on Oral Hygiene Skills in a Group of Autistic Egyptian Children Peer model, Pre-recorded video of peer modeling, Pedagogical method - Autism Disorder, Autism Spectrum Disorder (ASD | Not applicable | Not yet recruiting | Faculty of Dental Medicine for Girls | 90 | 2027-02-01 | 2026-10-06 |
| Frankincense Versus Sodium Hypochlorite for Root Canal Disinfection Sodium hypochlorite 3%, Frankincense-based irrigant - Pulp Necrosis, Root Canal Infection | Early Phase 1 | Not yet recruiting | Oman Dental College | 30 | 2027-01-19 | 2026-09-22 |
| Taste Acceptance and Effectiveness of Hyaluronic Acid and Chlorhexidine Mouthwashes in Children With Gingivitis Hyaluronic Acid mouthwash, Chlorohexidine 0.12% mouthwash - Plaque Induced Gingival Disease | Phase 1 | Not yet recruiting | Cairo University | 24 | 2027-01-01 | 2026-10-13 |
| Clinical and Radiographic Success of Calcium Hydroxide-Iodoform Paste Versus Modified Triple Antibiotic Paste for Necrotic Primary Molars in Children Calcium Hydroxide, Iodoform, paste, modified triple antibiotic paste - Dental Pulp Necrosis, Periapical Diseases | Not applicable | Not yet recruiting | Cairo University | 50 | 2027-01-01 | 2026-08-19 |
| Reconstructive Treatment of Peri-implantitis With Electrolytic Decontamination Versus Titanium Brushes test device GalvoSurge, Mechanical decontamination with titanium brush - Peri-Implantitis and Peri-implant Mucositis | Early Phase 1 | Not yet recruiting | George Eastman Dental Hospital, Italy | 38 | 2027-01-01 | 2026-09-11 |
| Alb-PRF as an Adjunct to Regenerative Periodontal Surgery Regenerative Periodontal Surgery With EDTA and Allogeneic Bone Graft, Albumin Platelet-Rich Fibrin - Periodontitis, Periodontitis Stage III | Not applicable | Not yet recruiting | Halil Ata BIÇAKÇIOĞLU | 24 | 2027-01-01 | 2026-09-04 |
| Effectiveness of Oil Pulling Using Oils in Comparison With Mouthwash for Gingivitis coconut oil, Sesame Oil, 0.2% Chlorhexidine Mouthwash - Gingivitis | Not applicable | Not yet recruiting | Bahria University | 45 | 2027-01-01 | 2026-10-27 |
| Rigid Versus Non-Rigid Digitally Fabricated Telescopic Double Crown Prosthesis Rigid telescopic double crown prosthesis, Non-rigid telescopic double crown prosthesis - Tooth Loss and Rehabilitation With Telescopic Crown Prostheses | Not applicable | Not yet recruiting | Mansoura University | 10 | 2026-12-22 | 2026-07-06 |
| Evaluating the Effect of Injectable Platelet-rich Fibrin on Accelerating Orthodontic Tooth Movement injectable form of PRF, Placebo injection - Tooth Mobility, Injectable Platelet-rich Fibrin | Not applicable | Recruiting | Hama University | 14 | 2026-12-20 | 2026-09-17 |
| Standard- and Micro-Dose rhBMP-2 for Implant Stability, Marginal Bone Loss, and Postoperative Sequelae: A Double-Blind Randomized Controlled Trial Standard-dose rhBMP-2, Micro-dose rhBMP-2, Sterile Normal Saline - Tooth Loss / Rehabilitation, Dental Implant | Not applicable | Not yet recruiting | University of Baghdad | 60 | 2026-12-01 | 2026-07-10 |
| Effectiveness of Toothpaste Tablets on Plaque, Gingival Health and Caries Experiences Toothpaste Tablet, Conventional Toothpaste - Gingival Inflammation, Dental Caries | Phase 3 | Not yet recruiting | Loma Linda University | 50 | 2026-12-01 | 2026-07-10 |
| Regenerative Outcomes for Peri-implant Bony Defects Using Amnion-chorion Barrier vs. Collagen Membrane BioXclude Amnion Chorion Membrane, Collagen Membrane - Peri-Implantitis | Not applicable | Not yet recruiting | Loma Linda University | 56 | 2026-12-01 | 2026-07-10 |
| Alb-PRF as an Adjunct to Nonsurgical Periodontal Therapy Nonsurgical Periodontal Therapy, Albumin Platelet-Rich Fibrin - Periodontitis | Not applicable | Not yet recruiting | Halil Ata BIÇAKÇIOĞLU | 24 | 2026-12-01 | 2026-08-31 |
| Individualized Management of Plaque-Related Gingival Inflammation in Routine Dental Practice Structured Preventive Care Workflow (iMGi) - Plaque-Induced Gingivitis | Not applicable | Not yet recruiting | Curaden AG | 100 | 2026-12-01 | 2026-10-20 |
| Efficacy of Thymus Vulgaris Mouthwash in the Management of Biofilm-Induced Gingivitis Thymus vulgaris mouthwash, Chlorhexidine 0,12%, Placebo mouthwash - Plaque-Induced Gingivitis | Phase 2 | Not yet recruiting | University of Sulaimani | 60 | 2026-12-01 | 2026-10-29 |
| Bone and Soft Tissue Healing After Socket Preservation With NOVAMag or Permamem Membranes NOVAMag Membrane, permamem Membrane, Alveolar Socket Preservation With an Allogeneic Bone Graft - Alveolar Bone Loss, Tooth Loss / Rehabilitation | Not applicable | Not yet recruiting | University of Zagreb | 50 | 2026-11-01 | 2026-10-07 |
Showing 20 of 3990. Sign in to see all of them.
Periodontitis (1212) · Gingivitis (607) · Gingival Recession (415) · Chronic Periodontitis (356) · Peri-Implantitis (318) · Alveolar Bone Loss (306) · Periapical Periodontitis (235) · Dental Plaque (170) · Tooth Loss (155) · Periodontal Pocket (127) · Diabetes Mellitus (100) · Inflammation (97) · Gingival Diseases (86) · Dental Caries (82)
Stomatognathic Diseases (3980) · Mouth Diseases (3966) · Gingival Diseases (1054) · Pathological Conditions, Signs and Symptoms (849) · Periodontal Atrophy (750) · Pathologic Processes (690) · Infections (660) · Periodontitis (620) · Tooth Diseases (522) · Musculoskeletal Diseases (409) · Disease Attributes (395) · Chronic Disease (377) · Bone Diseases (349) · Jaw Diseases (313)
Tooth Exfoliation (206) · Root Planing (189) · Chlorhexidine (72) · Metronidazole (42) · Control Groups (36) · Amoxicillin (35) · Periodontal Index (34) · Hyaluronic Acid (29) · Low-Level Light Therapy (29) · Probiotics (28) · Lasers, Semiconductor (27) · Photochemotherapy (26) · Mouthwashes (23) · enamel matrix proteins (21) · hydrated silica gel-based toothpaste (21)
Cairo University (167) · Postgraduate Institute of Dental Sciences Rohtak (98) · University of Sao Paulo (59) · Ain Shams University (55) · Colgate Palmolive (55) · University of Baghdad (33) · Marmara University (32) · Universidad Complutense de Madrid (32) · University of Michigan (32) · Government Dental College and Research Institute, Bangalore (31) · Mansoura University (31) · Al-Azhar University (28) · Universidade Estadual Paulista Júlio de Mesquita Filho (27) · Gazi University (26) · Necmettin Erbakan University (25)
Turkey (Türkiye) (614) · United States (413) · Egypt (400) · Italy (268) · India (208) · Brazil (191) · Spain (155) · China (84) · France (79) · Germany (60) · United Kingdom (59) · Iraq (54) · Pakistan (52) · Sweden (50) · Canada (49)
Mauro P Santamaria, PhD (13) · Gaetano Isola (12) · Andrea Scribante, Associate Professor (7) · Andrea Scribante, DDS, PhD, MS (6) · Magda Mensi (6) · Timo Sorsa, Professor (6) · Ahmed Y Gamal, Professor (5) · Beral Afacan (5) · Claudio Stacchi, Dr (5) · Claudio Stacchi, Dr. (5) · Enilson A Sallum, PhD (5)
PMID 33197289, PMID 32383274, PMID 29926952, PMID 14158464, PMID 29926491, PMID 29926951, PMID 1058834, PMID 28303587, PMID 29926484, PMID 3457698, PMID 14121956, PMID 15726851, PMID 19968743, PMID 20590963, PMID 21238793, PMID 23627374, PMID 24641000, PMID 26285807, PMID 26427036, PMID 26701919, PMID 27310522, PMID 29876969, PMID 30536725, PMID 34790237, PMID 36194420, PMID 5237684, PMID 12694427, PMID 12897619, PMID 14651280, PMID 14710766, PMID 14742657, PMID 15643744, PMID 15691354, PMID 16018754, PMID 16332231, PMID 16504850, PMID 16504852, PMID 16878680, PMID 17355365, PMID 17397320, PMID 17514885, PMID 17555414, PMID 18573992, PMID 18596969, PMID 18724852, PMID 19089687, PMID 19335093, PMID 19345793, PMID 19682173, PMID 20618550
2019 (5), 2018 (4), 2023 (4), 2008 (2), 2015 (2), 2016 (2), 2017 (2), 2025 (2), R44HL101821 (2), U01DE014577 (2), 1UG3DE030401-01 (1), 4UH3DE030856-03 (1), 4UH3DE031129-02 (1), D43TW012274 (1), K01DE027087 (1)