70 completed, 28 unknown, 25 recruiting, 11 not yet recruiting. 104 Not applicable, 7 Phase 4, 4 Phase 2, 3 Phase 3, 1 Phase 1.
Follow Tooth Loss: new trials by email Literature Review of Tooth Loss trials Research Report on Tooth Loss
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Rigid Versus Non-Rigid Digitally Fabricated Telescopic Double Crown Prosthesis Rigid telescopic double crown prosthesis, Non-rigid telescopic double crown prosthesis - Tooth Loss and Rehabilitation With Telescopic Crown Prostheses | Not applicable | Not yet recruiting | Mansoura University | 10 | 2026-12-22 | 2026-07-06 |
| Standard- and Micro-Dose rhBMP-2 for Implant Stability, Marginal Bone Loss, and Postoperative Sequelae: A Double-Blind Randomized Controlled Trial Standard-dose rhBMP-2, Micro-dose rhBMP-2, Sterile Normal Saline - Tooth Loss / Rehabilitation, Dental Implant | Not applicable | Not yet recruiting | University of Baghdad | 60 | 2026-12-01 | 2026-07-10 |
| Bone and Soft Tissue Healing After Socket Preservation With NOVAMag or Permamem Membranes NOVAMag Membrane, permamem Membrane, Alveolar Socket Preservation With an Allogeneic Bone Graft - Alveolar Bone Loss, Tooth Loss / Rehabilitation | Not applicable | Not yet recruiting | University of Zagreb | 50 | 2026-11-01 | 2026-10-07 |
| Ovate Pontic Versus Essix Provisional After Tooth Extraction and Alveolar Ridge Preservation (Pontic-Essix) Bio-Oss Collagen, Mucograft Seal, Fixed 3D-printed ovate pontic provisional restoration - Tooth Loss / Rehabilitation, Tooth Extraction | Not applicable | Not yet recruiting | University of Bern | 40 | 2026-10-01 | 2026-08-06 |
| Volumetric Efficacy of Alveolar Ridge Preservation Spontaneous Healing, d-PTFE Membrane, Leukocyte- and Platelet-Rich Fibrin (L-PRF) - Alveolar Ridge Preservation, Tooth Loss | Not applicable | Recruiting | Universidad del Desarrollo | 70 | 2026-09-15 | 2026-09-10 |
| Evaluation of Enamel Matrix Derivative in Immediate Dental Implants in the Mandibular Molar Region Enamel Matrix Derivative (Emdogain), Immediate Dental Implant Placement - Tooth Loss | Not applicable | Recruiting | Mansoura University | 24 | 2026-09-11 | 2026-09-16 |
| Tissue Preservation in Immediate 1C Implants Using an Anatomical Prefabricated Healing Abutment scannable anatomical healing abutment, Standard Healing Abutment for Dental Implants - Tooth Loss, Dental Implant | Not applicable | Not yet recruiting | University of Illinois at Chicago | 30 | 2026-09-01 | 2026-07-27 |
| Soft Tissue Augmentation Around Dental Implants Using Connective Tissue Graft, Submerged Tenting Abutment, or Sub-crestal Implant Placement subepithelial connective tissue graft, Submerged Tenting Abutment, Sub-crestal Implant Placement - Peri-implant Soft Tissue Deficiency, Partial Edentulism | Not applicable | Recruiting | Misr International University | 30 | 2026-07-17 | 2026-07-21 |
| 3D-Printed Versus Band-and-Loop Versus Denovo Space Maintainers in Primary Dentition. 3D-Printed Custom Space Maintainer, Conventional Band-and-Loop Space Maintainer, Denovo Chairside Space Maintainer - Space Maintenance, Tooth Loss / Rehabilitation | Not applicable | Active not recruiting | Murad Alrashidi | 360 | 2026-06-01 | 2026-10-13 |
| Glass Fiber-Reinforced Composite Resin Versus Band-and-Loop Space Maintainers in Children: A Split-Mouth Clinical Study Glass Fiber-Reinforced Composite Resin (GFRCR) Space Maintainer, Conventional Band-and-Loop Space Maintainer - Premature Loss of Primary Teeth, Space Maintenance | Not applicable | Completed | Ali Assiry | 20 | 2026-04-25 | 2026-07-28 |
| Influence of Implant Insertion Depth on Peri-implant Bone Changes Around Short Implants Subcrestal Dental Implant Placement, Crestal Dental Implant Placement - Tooth Loss, Edentulism | Not applicable | Not yet recruiting | Gulf Medical University | 58 | 2026-03-30 | 2026-03-13 |
| Effect of Mandibular Drilling Speed on Implant Stability and Osteogenic Potential: A Randomized Clinical Trial Implant osteotomy using biological drilling at 50 rpm without irrigation., Implant osteotomy using biological drilling at 150 rpm without irrigation., Implant osteotomy using biological drilling at 300 rpm without irrigation. - Edentulism, Tooth Loss | Not applicable | Not yet recruiting | Cairo University | 36 | 2026-03-15 | 2026-03-16 |
| Mandibular Biological Drilling at Different Speeds for Dental Implant Placement biological drilling at 50 RPM, biological drilling at 150 RPM, biological drilling at 300 RPM - Edentulism, Tooth Loss | Not applicable | Not yet recruiting | Cairo University | 39 | 2026-03-15 | 2026-03-16 |
| Clinical Safety and Effectiveness of the Straumann Dynamic Navigation System Falcon Post-operative Cone Beam Computed Tomography (CBCT), Straumann Falcon Dynamic Navigation System, Dental Implants - Partially Edentulous Jaw, Tooth Loss | Not applicable | Recruiting | Institut Straumann AG | 75 | 2026-01-22 | 2026-04-08 |
| Sleeved vs. Sleeveless Guides for Immediate Implant Placement Conventional Sleeved Static Surgical Guide, Sleeveless Static Surgical Guide - Tooth Loss, Maxillary Premolar Area | Not applicable | Active not recruiting | Mansoura University | 80 | 2026-01-01 | 2026-09-29 |
| In Vivo Evaluation of the Accuracy of Immediate Screw-Retained Provisional Crowns Fabricated Using Digital Planning and Guided Surgery Fully Guided Implant Placement and Immediate Provisionalization - Partial Edentulism, Tooth Loss / Rehabilitation | Not applicable | Recruiting | Universidad Complutense de Madrid | 27 | 2026-01-01 | 2026-01-09 |
| Effect of Different Loading Protocols on Photofunctionalized Implants in the Posterior Maxilla Immediate loading of UV-photofunctionalized dental implants, Early loading of UV-photofunctionalized dental implants, Conventional loading of UV-photofunctionalized dental implants - Tooth Loss, Surface Treatment | Not applicable | Active not recruiting | Mansoura University | 60 | 2026-01-01 | 2026-07-14 |
| Autogenous Tooth Transplantation With Instrumentally Simulated Open Apex and Platelet-Rich Fibrin Autogenous Tooth Transplantation, Alveolar Prf graft - Tooth Loss, Tooth Diseases | Not applicable | Recruiting | University of Bari Aldo Moro | 5 | 2026-01-01 | 2026-02-06 |
| Clinical Performance of Nobel N1 System Nobel N1 implant - Tooth Loss, Dental Implant | Phase 4 | Recruiting | Louisiana State University Health Sciences Center in New Orleans | 50 | 2025-12-15 | 2026-08-27 |
| PMCF Study on The Performance and Safety of ON DENT® PMMA Discs/Blocks and Resin Products for Temporary Restorations Temporary Fixed Prosthesis (Tempo-CAD Monocolor PMMA), Temporary Fixed Prosthesis (Tempo-CAD Monocolor SHT PMMA), Temporary Fixed Prosthesis (Tempo-CAD Multicolor SHT PMMA) - Tooth Loss, Dentin Caries | Not applicable | Recruiting | On Dent Tibbi Malzeme Dis Protez Ith. ve Ihr. San. Ltd. Sti. | 120 | 2025-12-05 | 2026-06-10 |
Showing 20 of 155. Sign in to see all of them.
Alveolar Bone Loss (10) · Dental Caries (7) · Mouth, Edentulous (7) · Bone Resorption (5) · Periodontitis (5) · Jaw, Edentulous (4) · Periodontal Diseases (4) · Jaw, Edentulous, Partially (3) · Tooth Fractures (3) · Anodontia (2) · Bone Diseases, Metabolic (2) · Diabetes Mellitus (2) · Gingival Recession (2) · Peri-Implantitis (2)
Mouth Diseases (155) · Stomatognathic Diseases (153) · Tooth Diseases (153) · Periodontal Diseases (151) · Musculoskeletal Diseases (24) · Bone Diseases (18) · Periodontal Atrophy (12) · Bone Resorption (10) · Jaw Diseases (9) · Tooth Demineralization (7) · Pathological Conditions, Signs and Symptoms (6) · Metabolic Diseases (5) · Mouth, Edentulous (5) · Nutritional and Metabolic Diseases (5) · Wounds and Injuries (5)
Dental Implants (6) · Bone Transplantation (3) · Immediate Dental Implant Loading (2) · Transplantation, Heterologous (2) · Transplantation, Homologous (2) · Acetaminophen (1) · Alloderm (1) · Anesthesia, General (1) · Antibiotic Prophylaxis (1) · Bone Morphogenetic Protein 2 (1) · Control Groups (1) · Dental Implantation (1) · Dental Prosthesis, Implant-Supported (1) · Denture, Partial, Removable (1) · Drug Implants (1)
Cairo University (10) · Mansoura University (7) · Institut Straumann AG (6) · Ege University (4) · Saint-Joseph University (3) · Suez Canal University (3) · University of Bari Aldo Moro (3) · University of Iowa (3) · University of Liege (3) · Akdeniz University (2) · CeraRoot SL (2) · Columbia University (2) · Heidelberg University (2) · McGuire Institute (2) · Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University (2)
United States (34) · Egypt (19) · Turkey (Türkiye) (10) · Spain (9) · Germany (7) · Italy (7) · France (5) · Switzerland (5) · China (4) · Belgium (3) · Brazil (3) · Canada (3) · Saudi Arabia (3) · United Kingdom (3) · Iraq (2)
Gustavo Avila-Ortiz, DDS, MS, PhD (2) · Abdullah Kalayci, Professor (1) · Abeer Gawish, professor (1) · Adeline Braud (1) · Ahmed Abdelmohsen Younis, Associate Professor of Oral an (1) · Albert M Price, DMD (1) · Alexey Y. Drobyshev, MD,PhD,Prof. (1) · Anastasia Cholakis, DDS (1) · Andy Temmerman, Professor (1) · Angela Palaiologou-Gallis, DDS, MS (1) · Anton Sculean, Dr med dent (1) · Bachar A Husseini, DDS (1) · Bishi AlGarni, MSc (1) · Bojan B Petrovic, PhD (1)
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2023 (1), R01DE012215 (1)