57 completed, 12 unknown, 7 recruiting, 5 not yet recruiting. 50 Not applicable, 15 Phase 4, 9 Phase 2, 7 Phase 3, 4 Phase 1.
Follow Mouthwashes: new trials by email Literature Review of Mouthwashes trials Research Report on Mouthwashes
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Taste Acceptance and Effectiveness of Hyaluronic Acid and Chlorhexidine Mouthwashes in Children With Gingivitis Hyaluronic Acid mouthwash, Chlorohexidine 0.12% mouthwash - Plaque Induced Gingival Disease | Phase 1 | Not yet recruiting | Cairo University | 24 | 2027-01-01 | 2026-10-13 |
| Evaluation of the Mouthwash Effect on Maintaining Healthy Microbiome in Healthy Mouth. Mouthwash - Healthy Mouth Microbiome | Not applicable | Not yet recruiting | Lacer S.A. | 40 | 2026-10-01 | 2026-09-28 |
| Stingless Bee Honey Mouth Rinse on Gingivitis mouth rinse, scaling, oral hygiene education and instruction - Gingivitis | Early Phase 1 | Not yet recruiting | Ministry of Higher Education, Malaysia | 60 | 2026-09-06 | 2026-08-19 |
| Effect of Oral Ice Chips to Prevent Chemotherapy-Induced Oral Mucositis in Patient With Solid Tumor Treated With 5 Fluorouracil and Methotrexate Oral Cryotherapy (Ice Chips), Standard Oral Care (Mouthwash) - Chemotherapy Induced Oral Mucositis | Not applicable | Not yet recruiting | University of Health Sciences Lahore | 102 | 2026-07-15 | 2026-06-16 |
| Evaluate the Efficacy of an Oral Health Behavioral Intervention in People With Diabetes Diabetes Oral Health Program, Stannous Fluoride Dentifrice, Cetylpyridinium Chloride (CPC) and Zinc Lactate Mouthwash - Diabetes Type 2, Periodontal Disease | Phase 4 | Enrolling by invitation | Colgate Palmolive | 10000 | 2026-05-26 | 2026-09-03 |
| Effects of Different Caffeine Forms on Aerobic and Anaerobic Exercise Performance Comparative Acute Effects of Caffeine Delivery Forms (Capsule, Chewing Gum, Mouth Rinse) on Aerobic Capacity and Wingate Anaerobic Performance Outcomes in Recreational Male Athletes: A Randomized Coun - Exercise Performance, Physical Performance | Not applicable | Completed | University of Gaziantep | 14 | 2026-04-20 | 2026-08-20 |
| Frankincense and Herbal Extracts for Plaque-Induced Gingivitis: A Double-Blind RCT Frankinscence and coconut Oil based mouthwash, Frankinscence and Thyme essence/ water based mouthwash, Chlorhexidine (0.2%) - Gingivitis | Not applicable | Completed | Oman Dental College | 99 | 2026-04-19 | 2026-09-02 |
| Traditional Chinese Medicine Preparation Alleviates Radiotherapy-induced Oral Mucositis in Head and Neck Cancer Patients. Placebo oral liquid and mouthwash, Zishui Daohuo oral liquid combined with Kujiu mouthwash, Radiotherapy - Radiotherapy-induced Oral Mucositis | Phase 2 | Recruiting | West China Hospital | 128 | 2026-03-30 | 2026-03-25 |
| Traditional Chinese Medicine Oral Liquids and Mouthwashes for Radiation-induced Oral Mucositis in Head and Neck Cancer Patients Qingying oral liquid and modified Da Huang-Huang Lian Xiexin mouthwash, Placebo oral solution and mouthwash, radiotherapy - Radiation-induced Oral Mucositis | Phase 2 | Recruiting | West China Hospital | 118 | 2026-03-16 | 2026-03-25 |
| Evaluation of the Effect of the Mouthwash on Delicate Gums Mouthwash for delicate gums - Gingivitis | Not applicable | Completed | Lacer S.A. | 33 | 2026-03-03 | 2026-08-26 |
| Evaluation of the Anti-plaque Effect of a Bioflavonoid-based Antiseptic Mouthwash Bioflavonoid mouthwash, Chlorhexidine 0.12% mouthwash - Gingival Inflammation, Dental Plaque Accumulation | Phase 4 | Completed | University of Barcelona | 24 | 2026-03-02 | 2026-09-17 |
| Evaluation of the Anti-Plaque Effect of a Resveratrol-Based Mouthwash Using a 24-Hour Plaque Re-Growth Resveratrol-Based Mouthwash, Chlorhexidine Gluconate 0.12 % Mouthwash, Placebo mouthwash - Mouthwash, Chlorhexidine | Phase 3 | Not yet recruiting | University of Baghdad | 20 | 2026-03-01 | 2026-02-06 |
| Effects of Three Different Methods Applied to Patients After Spine Surgery on Nausea, Thirst and Comfort Ice cube, Mouth wash, Menthol lozenge - Spinal Surgery | Not applicable | Completed | Ondokuz Mayıs University | 128 | 2026-02-28 | 2026-10-02 |
| Comparison Between the Effect of Triclosan Toothpaste and Chlorhexidine Mouthwash on Gingival Health in a Group of Fixed Orthodontic Patients: A Randomized Controlled Clinical Trial Triclosan 0.3% toothpaste, sodium fluoride 0.24% toothpaste, Chlorhexidine 0.2% mouthwash - Gingival Inflammation | Phase 4 | Completed | University of Science and Technology, Yemen | 60 | 2026-02-14 | 2026-09-11 |
| PMPR and Chlorhexidine on Periodontal Disease and Vascular Function Chlorhexidine (0.2%) mouthwash, Placebo mouthwash - Periodontal Disease (PD), Cardio Vascular Disease | Not applicable | Recruiting | Mahdi Mutahar | 30 | 2026-01-23 | 2026-03-25 |
| Antiplaque Efficacy and Patient Reported Outcome of Chlorohexidine, Cetylpyridinium Chloride, and Essential Oil Mouthwashes in Orthodontic Patients Chlorohexidine 0.12% mouthwash, Cetylpyridinium chloride 0.05% mouthwash, Essential Oil mouthwash - Effectiveness of Chlorohexidine, Effectiveness of Essential Oil | Not applicable | Completed | University of Baghdad | 20 | 2026-01-05 | 2026-07-07 |
| Comparison of the Efficacy of Clobetasol Propionate 0.05% Mouthwash, Photobiomodulation, and Their Combination in Managing of Oral Lesions in Patient With Pemphigus Vulgaris. Clobetasol propionate 0.05% Mouthwash, diode laser for photobiomodulation, clobetasol propionate 0.05% mouthwash + photobiomodulation - Oral Lesions in Patients With Pemphigus Vulgaris | Not applicable | Recruiting | Damascus University | 30 | 2025-11-01 | 2026-06-11 |
| Evaluation of Efficacy of Antibacterial Activity of Licorice, Clove, and Chlorohexidine Mouthwashes on Salivary Streptococcus Mutans in a Group of Egyptian Children. Mouth wash - Dental Caries, Streptococcal Infections | Not applicable | Active not recruiting | British University In Egypt | 54 | 2025-10-06 | 2026-09-18 |
| MicroRepair® ABX vs Chlorhexidine 0.12% in Gingivitis Patients MicroRepair ABX mouthwash, Chlorhexidine 0.12% mouthwash - Gingivitis, Dental Plaque | Not applicable | Completed | University of Pavia | 40 | 2025-08-30 | 2026-04-23 |
| 0.2% Chlorhexidine vs MicroRepair ABX in Gingivitis MicroRepair ABX mouthwash, Chlorhexidine 0.2% mouthwash - Gingivitis and Periodontal Diseases, Dental Plaque | Not applicable | Completed | University of Pavia | 40 | 2025-08-30 | 2026-04-29 |
Showing 20 of 86. Sign in to see all of them.
Gingivitis (14) · COVID-19 (7) · Periodontal Diseases (7) · Dental Plaque (6) · Stomatitis (5) · Mucositis (4) · Periodontitis (4) · Diabetes Mellitus (3) · Diabetes Mellitus, Type 2 (3) · Head and Neck Neoplasms (3) · Chronic Periodontitis (2) · Dental Caries (2) · Halitosis (2) · Neoplasms (2) · Pharyngitis (2)
University of Pavia (4) · Johnson & Johnson Consumer Inc. (J&JCI) (3) · Lacer S.A. (3) · Augusta University (2) · Cairo University (2) · Colgate Palmolive (2) · Rowpar Pharmaceuticals, Inc. (2) · University of Baghdad (2) · University of Barcelona (2) · University of Santiago de Compostela (2) · University of Sao Paulo (2) · West China Hospital (2) · Aga Khan University (1) · Al-Azhar University (1) · British University In Egypt (1)
United States (16) · Spain (6) · Turkey (Türkiye) (6) · Italy (5) · Brazil (4) · China (4) · Egypt (4) · Iraq (3) · Taiwan (3) · Mexico (2) · Pakistan (2) · Saudi Arabia (2) · South Korea (2) · United Kingdom (2) · Belgium (1)
Andrea Scribante, Associate Professor (3) · Jeffery Milleman, DDS (3) · Abeer Aljoujou, PhD In Oral medicine (1) · Adhrie Sugiarto, MD (1) · Alexandra E Kejner, MD (1) · Andrea Scribante, DDS, PhD (1) · Andrew M Jones, PhD (1) · Aziz Sheikh, MD, PhD (1) · Brad S Kahl, M.D. (1) · Carla R Fontana, Ph.D (1) · Chris Kenyon, MD (1) · Christopher Cutler, DDS (1) · Dashnor Bukleta, Dr (1) · Diego PV Leite, DDS (1)
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R21DE020916 (1)