4179 completed, 1318 unknown, 704 recruiting, 422 not yet recruiting. 3574 Not applicable, 958 Phase 2, 503 Phase 3, 422 Phase 1, 416 Phase 4.
Follow Mouth Diseases: new trials by email Literature Review of Mouth Diseases trials Research Report on Mouth Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| 9-ING-41 Plus Carboplatin in Patients With Advanced, Metastatic Salivary Gland Carcinoma 9-ING-41, Carboplatin - Salivary Gland Carcinoma, Adenoid Cystic Carcinoma | Phase 2 | Withdrawn | Actuate Therapeutics Inc. | 2030-12-18 | 2022-02-22 | |
| Outcomes in Stevens Johnsons Syndrome and Toxic Epidermal Necrolysis Site specific standard of care comparison - Stevens-Johnson Syndrome, Toxic Epidermal Necrolysis | Withdrawn | Massachusetts General Hospital | 2030-01-01 | 2026-01-16 | ||
| Dimensional Changes: Randomized Clinical Trial Gum Graft Placed on Denuded Bone, Gum Graft Placed on Split Thickness Periosteal Bed Preparation - Gingival Recession | Not applicable | Not yet recruiting | University of Iowa | 50 | 2028-08-01 | 2026-09-09 |
| Methadone as an Alternative Treatment for Children Underdoing HSCT PCA plus methadone (Experimental), PCA Alone (SOC) - Leukemia, Aplastic Anemia | Phase 3 | Suspended | University of Texas Southwestern Medical Center | 60 | 2028-01-01 | 2025-10-23 |
| Autogenous Mesenchymal Stem Cell Culture-Derived Signalling Molecules as Enhancers of Bone Formation in Bone Grafting Maxillary sinus floor elevation grafting with synthetic bone substitute. - Bone Loss, Osteoclastic, Bone Loss, Alveolar | Phase 1 | Not yet recruiting | Pontificia Universidade Católica do Rio Grande do Sul | 20 | 2027-12-15 | 2026-09-21 |
| Efficacy of Different Disinfection Technologies in Molar Non-Surgical Retreatment GentleWave System, Conventional rotary instrumentation with passive ultrasonic irrigation - Apical Periodontitis | Not applicable | Not yet recruiting | University of Alabama at Birmingham | 60 | 2027-07-01 | 2026-04-08 |
| Education-Based Oral Health Promotion Intervention During Pregnancy: Implementation Protocol in Bangladesh Integrated Oral Health Promotion Package (IOHPP) - Pregnancy, Periodontal Diseases | Not applicable | Not yet recruiting | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | 688 | 2027-06-01 | 2026-10-21 |
| Mindfulness in Nonflaccid Facial Paralysis Mindfulness Sessions, No Mindfulness Sessions - Facial Paralysis | Not applicable | Not yet recruiting | Wake Forest University Health Sciences | 24 | 2027-04-01 | 2026-09-30 |
| Focused Versus Multi-Target Trigger Point Injection for Chronic Myofascial Neck Pain Lidocaine 1% Trigger Point Injection - Myofacial Pain Syndrome, Chronic Neck Pain | Not applicable | Not yet recruiting | Mardin Artuklu University | 100 | 2027-04-01 | 2026-10-20 |
| Risk Factors of Jaw Osteoradionecrosis in Oral Cavity Cancer Patients Post-Radiotherapy Osteoradionecrosis, Radiotherapy | Not yet recruiting | AO Innovation Translation Center | 1000 | 2027-03-01 | 2026-09-23 | |
| Testing the Addition of an Anti-Cancer Drug, Camonsertib, to Radiation Therapy for Recurrent Head and Neck Squamous Cell Carcinoma Biospecimen Collection, Camonsertib, Computed Tomography - Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Recurrent Head and Neck Squamous Cell Carcinoma | Phase 1 | Recruiting | National Cancer Institute (NCI) | 39 | 2027-02-13 | 2026-09-03 |
| Effectiveness of Interactive Techniques on Oral Hygiene Skills in a Group of Autistic Egyptian Children Peer model, Pre-recorded video of peer modeling, Pedagogical method - Autism Disorder, Autism Spectrum Disorder (ASD | Not applicable | Not yet recruiting | Faculty of Dental Medicine for Girls | 90 | 2027-02-01 | 2026-10-06 |
| Frankincense Versus Sodium Hypochlorite for Root Canal Disinfection Sodium hypochlorite 3%, Frankincense-based irrigant - Pulp Necrosis, Root Canal Infection | Early Phase 1 | Not yet recruiting | Oman Dental College | 30 | 2027-01-19 | 2026-09-22 |
| Taste Acceptance and Effectiveness of Hyaluronic Acid and Chlorhexidine Mouthwashes in Children With Gingivitis Hyaluronic Acid mouthwash, Chlorohexidine 0.12% mouthwash - Plaque Induced Gingival Disease | Phase 1 | Not yet recruiting | Cairo University | 24 | 2027-01-01 | 2026-10-13 |
| Clinical and Radiographic Success of Calcium Hydroxide-Iodoform Paste Versus Modified Triple Antibiotic Paste for Necrotic Primary Molars in Children Calcium Hydroxide, Iodoform, paste, modified triple antibiotic paste - Dental Pulp Necrosis, Periapical Diseases | Not applicable | Not yet recruiting | Cairo University | 50 | 2027-01-01 | 2026-08-19 |
| Reconstructive Treatment of Peri-implantitis With Electrolytic Decontamination Versus Titanium Brushes test device GalvoSurge, Mechanical decontamination with titanium brush - Peri-Implantitis and Peri-implant Mucositis | Early Phase 1 | Not yet recruiting | George Eastman Dental Hospital, Italy | 38 | 2027-01-01 | 2026-09-11 |
| Penn SICCA Follow-up Study Dry Eye, Sjogren's Syndrome | Not yet recruiting | University of Pennsylvania | 220 | 2027-01-01 | 2026-03-02 | |
| Alb-PRF as an Adjunct to Regenerative Periodontal Surgery Regenerative Periodontal Surgery With EDTA and Allogeneic Bone Graft, Albumin Platelet-Rich Fibrin - Periodontitis, Periodontitis Stage III | Not applicable | Not yet recruiting | Halil Ata BIÇAKÇIOĞLU | 24 | 2027-01-01 | 2026-09-04 |
| Prevention of Oral Mucositis in Adults in With Hematologic Malignancy Aloe Vera Mouthwash, Standard of Care - Acute Leukemia, Acute Myeloid Leukemia | Not applicable | Not yet recruiting | Wake Forest University Health Sciences | 206 | 2027-01-01 | 2026-10-22 |
| Effectiveness of Oil Pulling Using Oils in Comparison With Mouthwash for Gingivitis virgin coconut oil (VCO), Sesame Oil, 0.2% Chlorhexidine Digluconate Mouthwash - Gingivitis | Not applicable | Not yet recruiting | Bahria University | 45 | 2027-01-01 | 2026-10-23 |
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Periodontitis (1207) · Periodontal Diseases (864) · Gingivitis (606) · Mouth Neoplasms (443) · Gingival Recession (415) · Head and Neck Neoplasms (401) · Chronic Periodontitis (356) · Peri-Implantitis (318) · Sjogren's Syndrome (318) · Alveolar Bone Loss (305) · Squamous Cell Carcinoma of Head and Neck (298) · Stomatitis (291) · Xerostomia (275) · Salivary Gland Neoplasms (239) · Periapical Periodontitis (232)
Stomatognathic Diseases (7332) · Periodontal Diseases (3116) · Pathological Conditions, Signs and Symptoms (1478) · Musculoskeletal Diseases (1074) · Gingival Diseases (1053) · Infections (1024) · Neoplasms (1010) · Neoplasms by Site (998) · Salivary Gland Diseases (941) · Pathologic Processes (926) · Skin and Connective Tissue Diseases (859) · Tooth Diseases (805) · Periodontal Atrophy (749) · Nervous System Diseases (669)
Tooth Exfoliation (206) · Root Planing (188) · Chlorhexidine (82) · Low-Level Light Therapy (80) · Cisplatin (70) · Radiotherapy (51) · Metronidazole (47) · Control Groups (46) · Probiotics (42) · Amoxicillin (41) · Surveys and Questionnaires (40) · Dental Implants (38) · Photochemotherapy (38) · Saline Solution (38) · Hyaluronic Acid (36)
Cairo University (276) · Postgraduate Institute of Dental Sciences Rohtak (103) · Ain Shams University (94) · National Cancer Institute (NCI) (77) · University of Sao Paulo (74) · Assiut University (59) · Colgate Palmolive (56) · Al-Azhar University (44) · GlaxoSmithKline (43) · Mansoura University (43) · Assistance Publique - Hôpitaux de Paris (41) · University of Michigan (40) · Marmara University (39) · M.D. Anderson Cancer Center (38) · Universidad Complutense de Madrid (37)
United States (1385) · Turkey (Türkiye) (756) · Egypt (684) · Italy (422) · China (331) · Brazil (311) · France (302) · India (273) · Spain (271) · Canada (176) · Germany (174) · United Kingdom (161) · Taiwan (134) · Pakistan (108) · Sweden (96)
Gaetano Isola (17) · Mauro P Santamaria, PhD (13) · Andrea Scribante, Associate Professor (10) · Timo Sorsa, Professor (7) · Andrea Scribante, DDS, PhD, MS (6) · Barbara Murphy, MD (6) · Ching-Mao Chang, M.D., Ph.D. (6) · Claudio Stacchi, Dr (6)
PMID 33197289, PMID 32383274, PMID 29926952, PMID 14158464, PMID 29926491, PMID 29926951, PMID 1058834, PMID 28303587, PMID 29926484, PMID 3457698, PMID 12361079, PMID 12988177, PMID 14121956, PMID 15172646, PMID 15726851, PMID 15979480, PMID 18457329, PMID 18973181, PMID 19968743, PMID 20014446, PMID 20590963, PMID 20618550, PMID 20623305, PMID 21238793, PMID 21541945, PMID 22108231, PMID 22422558, PMID 22864015, PMID 23627374, PMID 23720248, PMID 24158342, PMID 24641000, PMID 24817237, PMID 25503901, PMID 26285807, PMID 26427036, PMID 26701919, PMID 27310522, PMID 28279391, PMID 29784145, PMID 29876969, PMID 30536725, PMID 31095438, PMID 32939030, PMID 34503735, PMID 34790237, PMID 36194420, PMID 39532605, PMID 39584361, PMID 5237684
2023 (13), 2025 (12), 2018 (11), P30CA068485 (11), 2015 (10), 2016 (9), 2019 (8), P30CA016672 (8), U10CA180868 (8), 2008 (7), P30CA006516 (7), 2014 (6), 2017 (5), P30CA023074 (5), U10CA180820 (5)