2333 completed, 784 unknown, 270 not yet recruiting, 267 recruiting. 2673 Not applicable, 226 Phase 2, 207 Phase 3, 185 Phase 4, 111 Phase 1.
Follow Tooth Diseases: new trials by email Literature Review of Tooth Diseases trials Research Report on Tooth Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Anticariogenic Effect of Moringa Oleifera Mouthwash Compared to Chlorhexidine Mouthwash Moringa Oleifera, Chlorhexidine mouthwash, Base formula - Plaque, Dental, Antimicrobial | Phase 2 / Phase 3 | Not yet recruiting | Misr International University | 90 | 2027-12-01 | 2026-10-08 |
| Nano Silver Fluoride and Photobiomodulation Therapy for Hypersensitivity and Pain in MIH-Affected Molars Nano Silver Fluoride, Photobiomodulation Therapy, Pre-appointment analgesics - Molar-Incisor Hypomineralization (MIH) | Not applicable | Not yet recruiting | Ain Shams University | 45 | 2027-05-01 | 2026-09-17 |
| Treatment of Skeletal Class II Malocclusion With Modified Twin-Block Appliance With Clear Plates Modified Twin-Block Appliance with Clear Plates., Traditional Twin-Block appliance - Malocclusion, Angle Class II | Not applicable | Recruiting | Hama University | 32 | 2027-03-15 | 2026-09-16 |
| The Effect of Bitewing Radiography on Outcomes and Costs of Treating Caries in Permanent Teeth Visual-tactile caries examination, Visual-tactile caries examination and bilateral bitewing radiography - Dental Caries, Teeth Loss | Not applicable | Not yet recruiting | Jukka Leinonen | 250 | 2027-03-01 | 2026-10-20 |
| Frankincense Versus Sodium Hypochlorite for Root Canal Disinfection Sodium hypochlorite 3%, Frankincense-based irrigant - Pulp Necrosis, Root Canal Infection | Early Phase 1 | Not yet recruiting | Oman Dental College | 30 | 2027-01-19 | 2026-09-22 |
| Clinical Performance of High Viscous Glass Ionomer Cervical Restorations With Silver-Modified Atraumatic Restorative Technique (SMART) Versus Conventional Treatment in Elderly Cancer Patients. (A 12-month Randomized Clinical Trial) Silver Diamine Fluoride (SDF, 38%), Conventional Tooth Preparation, High-Viscosity Glass Ionomer Cement - Dental Caries, Cervical Caries | Not applicable | Not yet recruiting | Cairo University | 30 | 2027-01-15 | 2026-10-19 |
| Multicenter Clinical Study on the Efficacy and Esthetic Outcomes of Immediate Implant Placement Using the Socket-Shield Technique Versus Conventional Immediate Implantation in the Anterior Maxillary Esthetic Zone the Socket Shield Technique (SST) immediate implant placement, Conventional immediate implant placement - Teeth Absent, Teeth Missing | Not applicable | Not yet recruiting | First Affiliated Hospital of Wenzhou Medical University | 48 | 2027-01-01 | 2026-09-16 |
| Effect of Hemostatic Agents on TheraCal PT Pulpotomy Success in Primary Molars 2.5% Sodium Hypochlorite applied to pulpal tissue/stumps for 3 minutes to achieve hemostasis prior to TheraCal PT placement during primary molar pulpotomy and 15% Ferric Sulfate (Astringedent™ 15.5%) - Reversible Pulpitis, Dental Caries | Not applicable | Not yet recruiting | Reem Mohamed Gaber | 75 | 2027-01-01 | 2026-10-15 |
| Clinical and Radiographic Success of Calcium Hydroxide-Iodoform Paste Versus Modified Triple Antibiotic Paste for Necrotic Primary Molars in Children Calcium Hydroxide, Iodoform, paste, modified triple antibiotic paste - Dental Pulp Necrosis, Periapical Diseases | Not applicable | Not yet recruiting | Cairo University | 50 | 2027-01-01 | 2026-08-19 |
| Evaluation of Corrective Surgery Versus Dental Implants in Compromised Mandibular Molars hemi sectioning - Root Caries, Vertical Root Fracture | Not applicable | Not yet recruiting | Ain Shams University | 28 | 2027-01-01 | 2026-06-08 |
| Evaluation of Corrective Surgery Versus Dental Implants in Compromised Upper Molars root amputation - Root Caries | Not applicable | Not yet recruiting | Ain Shams University | 28 | 2027-01-01 | 2026-05-27 |
| Applying Navigation and Care to Help Ongoing Retention Family Navigation, Usual Care - Child Obesity | Not applicable | Not yet recruiting | University of Alberta | 252 | 2027-01-01 | 2026-09-22 |
| Comparison of Orthodontic Molar Protraction With and Without Adjunctive Surgery Orthodontic Molar Protraction and PAOO, Orthodontic Molar Protraction - Malocclusion | Not applicable | Not yet recruiting | University of Alabama at Birmingham | 40 | 2027-01-01 | 2026-10-15 |
| Children Acceptance of AgNP Mouthwash Against Chlorhexidine 0.12% and Chlorhexidine .2% Mouthwashs nano silver mouthwash, Chlorhexidine mouthwash (0.12%), Chlorhexidine mouthwash (0.2%) - Teeth Staining, Numbness of the Tongue and Soft Tissue | Not applicable | Not yet recruiting | Cairo University | 93 | 2027-01-01 | 2026-10-21 |
| 3D Printed Occlusal Splints for Intraoperative Use Formlabs 3D printed occlusal splint, Industry made occlusal splint - Malocclusion, Angle Class I, Malocclusion, Angle Class II | Not applicable | Not yet recruiting | Johns Hopkins University | 70 | 2026-12-30 | 2026-08-11 |
| Rigid Versus Non-Rigid Digitally Fabricated Telescopic Double Crown Prosthesis Rigid telescopic double crown prosthesis, Non-rigid telescopic double crown prosthesis - Tooth Loss and Rehabilitation With Telescopic Crown Prostheses | Not applicable | Not yet recruiting | Mansoura University | 10 | 2026-12-22 | 2026-07-06 |
| Standard- and Micro-Dose rhBMP-2 for Implant Stability, Marginal Bone Loss, and Postoperative Sequelae: A Double-Blind Randomized Controlled Trial Standard-dose rhBMP-2, Micro-dose rhBMP-2, Sterile Normal Saline - Tooth Loss / Rehabilitation, Dental Implant | Not applicable | Not yet recruiting | University of Baghdad | 60 | 2026-12-01 | 2026-07-10 |
| Evaluation of Three Pulp Vitality Tests Laser Doppler Flowmetry - Dental Pulp Diseases, Dental Pulp Vitality Testing | Not yet recruiting | Columbia University | 150 | 2026-12-01 | 2026-02-04 | |
| Effectiveness of Toothpaste Tablets on Plaque, Gingival Health and Caries Experiences Toothpaste Tablet, Conventional Toothpaste - Gingival Inflammation, Dental Caries | Phase 3 | Not yet recruiting | Loma Linda University | 50 | 2026-12-01 | 2026-07-10 |
| Treatment of Mandibular Overjet in Children With Maxillary Retrognathism Interceptive treatment - Maxillary Retrognathism, Children | Not applicable | Not yet recruiting | Malmö University | 180 | 2026-12-01 | 2026-10-22 |
Showing 20 of 3987. Sign in to see all of them.
Dental Caries (1005) · Dental Plaque (335) · Dentin Sensitivity (286) · Malocclusion (276) · Gingivitis (166) · Tooth Loss (155) · Dental Pulp Necrosis (151) · Bruxism (149) · Toothache (139) · Dental Pulp Diseases (130) · Molar Hypomineralization (130) · Mouth, Edentulous (123) · Malocclusion, Angle Class II (120) · Jaw, Edentulous (118) · Tooth, Impacted (118)
Stomatognathic Diseases (3967) · Tooth Demineralization (1067) · Mouth Diseases (800) · Pathological Conditions, Signs and Symptoms (621) · Periodontal Diseases (438) · Dental Pulp Diseases (361) · Signs and Symptoms (354) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (350) · Dental Deposits (349) · Congenital Abnormalities (344) · Stomatognathic System Abnormalities (337) · Jaw Diseases (326) · Musculoskeletal Diseases (321) · Pathologic Processes (319)
Low-Level Light Therapy (48) · Sodium Fluoride (43) · Dental Implants (32) · silver diamine fluoride (31) · Fluorides (27) · Calcium Hydroxide (24) · Control Groups (24) · mineral trioxide aggregate (24) · Chlorhexidine (23) · Ibuprofen (23) · Toothpastes (23) · Pemetrexed (22) · Orthodontic Appliances, Fixed (21) · Sodium Hypochlorite (21) · Pulpotomy (20)
Cairo University (353) · Damascus University (87) · Al-Azhar University (69) · University of Sao Paulo (58) · GlaxoSmithKline (56) · Colgate Palmolive (53) · Hacettepe University (51) · Ain Shams University (49) · Mansoura University (49) · Marmara University (43) · HALEON (32) · University of Nove de Julho (29) · The University of Hong Kong (28) · Dentsply Sirona Implants and Consumables (25) · Postgraduate Institute of Dental Sciences Rohtak (25)
United States (588) · Egypt (568) · Turkey (Türkiye) (433) · Brazil (249) · Italy (136) · Syria (102) · France (98) · Spain (98) · China (97) · United Kingdom (90) · Pakistan (77) · Canada (60) · Germany (58) · Switzerland (55) · India (51)
Mohammad Y Hajeer, DDS MSc PhD (17) · Andrea Scribante, DDS, PhD (9) · Mohammad Y Hajeer, DDS,MSc,PhD (9) · Andrea Scribante, Associate Professor (8) · Mathilde C Peters, DMD, PhD (6) · Bennett T Amaechi, BDS, MS, PhD (5) · Daniela P Raggio, Professor (5) · Gregg H Gilbert, DDS, MBA (5) · Henry Greenwell, DMD (5) · Jeffery L Milleman, DDS, MPA (5) · Nehal Amir, BDS (5) · Peter Milgrom, DDS (5)
PMID 20932395, PMID 24158342, PMID 26964798, PMID 31164116, PMID 5264376, PMID 10343087, PMID 11132515, PMID 12218274, PMID 14489483, PMID 1452871, PMID 1592970, PMID 16211157, PMID 17518963, PMID 18341239, PMID 18434577, PMID 19365118, PMID 19696851, PMID 20723019, PMID 21055598, PMID 22128671, PMID 22211303, PMID 22257664, PMID 23190278, PMID 23640952, PMID 23972577, PMID 24182579, PMID 24843394, PMID 25045768, PMID 25443280, PMID 25634162, PMID 25677244, PMID 25905656, PMID 26588111, PMID 27009835, PMID 27093773, PMID 28410008, PMID 30264270, PMID 30500094, PMID 30883951, PMID 31640741, PMID 31839988, PMID 33514787, PMID 33653326, PMID 34083157, PMID 3457698, PMID 34676918, PMID 34743243, PMID 35656656, PMID 37138297, PMID 37266982
U01DE016747 (7), 2019 (5), 2014 (4), 2009 (2), 2015 (2), 2017 (2), 2023 (2), 2025 (2), D43TW007768 (2), K23DE023579 (2), U54DE014254 (2), 1UG3DE029443-01 (1), 1UL1RR024148 (1), 2005 (1), 2008 (1)