254 completed, 100 unknown, 30 recruiting, 26 terminated. 155 Phase 4, 103 Not applicable, 89 Phase 2, 80 Phase 3, 32 Phase 1.
Follow Metronidazole: new trials by email Literature Review of Metronidazole trials Research Report on Metronidazole
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Piperacillin/Tazobactam Versus Ceftriaxone and Metronidazole for Children With Perforated Appendicitis Piperacillin/Tazobactam, Ceftriaxone + Metronidazole - Appendicitis Perforated, Appendectomy, Laparoscopic | Phase 3 | Not yet recruiting | McMaster Children's Hospital | 180 | 2027-04-01 | 2026-10-09 |
| A Study to Test New Investigational Drugs (LCFA-01and LC103) for Bacterial Vaginosis (BV) Treatment metronidazole (MTZ)+ LCFA-01 placebo + LC103 placebo, metronidazole (MTZ)+ LCFA-01 + LC103 placebo, metronidazole (MTZ)+ LC103 + LCFA-01 placebo - Bacterial Vaginosis | Phase 1 | Not yet recruiting | Massachusetts General Hospital | 280 | 2027-02-03 | 2026-10-15 |
| Antibiotics After Incision and Drainage to Prevent Fistula Formation After First Episode of Perianal Abscess Amoxicillin + Clavulanate, Ciprofloxacin + Metronidazole - Perianal Abscess, Anal Fistula | Phase 4 | Not yet recruiting | University of Illinois at Chicago | 236 | 2026-10-05 | 2026-09-21 |
| AUTOP 2: Screen-and-treat Strategy for Vaginal Flora Abnormalities by Molecular Biology in Pregnant Women at High Risk of Preterm Birth Vaginal flora abnormalities screening and quantification using molecular biology technique, Azithromycin, Ceftriaxone - Bacterial Vaginosis, Vaginal Dysbiosis | Phase 3 | Not yet recruiting | Assistance Publique Hopitaux De Marseille | 1794 | 2026-10-01 | 2026-08-27 |
| Photobiomodulation With Blue LED in Recurrent Bacterial Vaginosis Metronidazole, Blue Light-Emitting Diode (LED) - Bacterial Vaginosis | Not applicable | Not yet recruiting | Patricia Lordelo | 40 | 2026-09-30 | 2026-09-23 |
| Comparative Efficacy of Amoxicillin, Metronidazole, and Chlorhexidine in Preventing Alveolar Osteitis Amoxicillin, Metronidazole, Chlorhexidine - Alveolar Osteitis | Not applicable | Not yet recruiting | Khyber Medical University Peshawar | 240 | 2026-09-25 | 2026-10-14 |
| A Combination of Antibiotics to Decrease Neonatal Morbidity and Mortality for Previable Threatened Labor Combination of antibiotics, Emergency cerclage, Vaginal progesterone - Previable Labour With Intact Membranes | Phase 3 | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 350 | 2026-09-01 | 2026-05-01 |
| MOTIF@FRESH: Modifying Organisms Transvaginally in Females @ FRESH Vaginal Microbiome Transplantation (VMT), oral metronidazole, Sterile saline solution - Recurrent Bacterial Vaginosis (BV) | Phase 2 | Not yet recruiting | Douglas Kwon | 75 | 2026-09-01 | 2026-05-18 |
| Efficacy And Safety of Bismuth-Tetracycline-Rabeprazole Triple For First-Line Eradication of Helicobacter Pylori Infection Bismuth, Bismuth quadruple therapy - Helicobatcer Pylori, First-Line Eradication | Not applicable | Not yet recruiting | Chih-An Shih, MD | 300 | 2026-09-01 | 2026-08-26 |
| Pylori Duo for Adjunctive Treatment and Prevention of Recurrence of Helicobacter Pylori Infection Omeprazole, Pylera (Bismuth subcitrate potassium, metronidazole, tetracycline) given in combination with omeprazole, Pylori Duo - Helicobacter Pylori Infection, Dyspepsia | Not applicable | Not yet recruiting | Gala Servicios Clinicos S.L. | 140 | 2026-08-31 | 2026-07-27 |
| Metronidazole- Versus Tinidazole-Based Bismuth Quadruple Therapy for Helicobacter Pylori Eradication Metronidazole, Tinidazole 500mg, tetracyline - Helicobacter Pylori Infection | Not applicable | Not yet recruiting | University of Medicine and Pharmacy at Ho Chi Minh City | 600 | 2026-07-27 | 2026-08-05 |
| APLAUD Trial (Antibiotics vs PLacebo for Acute Uncomplicated Diverticulitis) Amoxicillin-Clavulanate 875 Mg-125 Mg Oral Tablet, Placebo, Metronidazole - Acute Uncomplicated Diverticulitis | Phase 2 | Recruiting | Vanderbilt University Medical Center | 100 | 2026-07-07 | 2026-09-21 |
| Non-antibiotic Management in Acute Uncomplicated Diverticulitis Symptomatic treatment (ibuprofen and acetaminophen), Amoxicillin-clavulanate, Ciprofloxacin plus metronidazole - Acute Uncomplicated Diverticulitis | Phase 4 | Withdrawn | Montefiore Medical Center | 2026-07-01 | 2026-08-31 | |
| Gut Decolonisation With Neomycin/Metronidazole or Rifaximin Before Colon Surgery Rifaximin (Xifaxan), Metronidazole, Neomycin Sulfate - Surgical Site Infection, Colon Surgery | Phase 4 | Not yet recruiting | Universität Luzern | 458 | 2026-06-01 | 2025-09-18 |
| Early Discontinuation of Antibiotics in Paediatric High-risk Febrile Neutropenia Early Discontinuation of Antibiotics, Standard Antibiotic Continuation Strategy - Febrile Neutropenia (FN), Pediatric Cancer | Phase 4 | Not yet recruiting | Hospital Universitari Vall d'Hebron Research Institute | 136 | 2026-06-01 | 2026-05-15 |
| Duration of Perioperative Antibiotics in Pancreatoduodenectomy single dose preoperative antibiotic, Prolonged perioperative antibiotics - Pancreatoduodenectomy, PPPD | Not applicable | Enrolling by invitation | Asan Medical Center | 558 | 2026-05-11 | 2026-05-28 |
| Comparative Efficacy of Antibiotics for Small Intestine Bacterial Overgrowth in Bangladeshi Children Trimethoprim-sulfamethoxazole (TMP/SMX), Metronidazole, Amoxicillin-Clavulanate (4:1 formulation) - Small Intestine Bacterial Overgrowth | Phase 2 | Recruiting | University of Virginia | 60 | 2026-04-18 | 2026-08-18 |
| The LISA (Lactoferrin InStead of Antibiotics/Antifungals) Feasibility Study Vaginal lactoferrin, Usual care - Bacterial Vaginosis, Candida Vaginal | Not applicable | Recruiting | Guy's and St Thomas' NHS Foundation Trust | 114 | 2026-04-16 | 2026-05-29 |
| Chlorhexidine and/or Metronidazole Plus FB301 Pre-treatment Trial FB 301, Chlorhexidine 0.5%, metronidazole 500 mg - Bacterial Vaginosis (BV) | Phase 2 | Recruiting | Freya Biosciences ApS | 120 | 2026-03-23 | 2026-08-06 |
| Comparison of Two Treatment Regimens of Helicobacter Pylori Infection Clarithromycin, Levofloxacin - Helicobacter Pylori Infection | Phase 4 | Not yet recruiting | Rehman Medical Institute - RMI | 156 | 2025-12-01 | 2025-06-15 |
Showing 20 of 458. Sign in to see all of them.
Vaginosis, Bacterial (48) · Appendicitis (25) · Surgical Wound Infection (20) · Periodontitis (17) · Periodontal Diseases (14) · Infections (12) · Chronic Periodontitis (10) · Colitis, Ulcerative (9) · Colorectal Neoplasms (9) · Vaginitis (9) · Helicobacter Infections (8) · Rosacea (8) · Aggressive Periodontitis (7) · Intraabdominal Infections (7) · Crohn Disease (6)
Shanghai Jiao Tong University School of Medicine (19) · Pfizer (11) · National Taiwan University Hospital (10) · Kaohsiung Veterans General Hospital. (9) · Shandong University (7) · Shanghai Zhongshan Hospital (6) · Merck Sharp & Dohme LLC (5) · Seoul National University Bundang Hospital (5) · Assistance Publique - Hôpitaux de Paris (4) · Chang Gung Memorial Hospital (4) · Galderma R&D (4) · HaEmek Medical Center, Israel (4) · Helsinki University Central Hospital (4) · National Institute of Allergy and Infectious Diseases (NIAID) (4) · University of Alabama at Birmingham (4)
United States (111) · China (52) · Taiwan (37) · Spain (18) · Brazil (17) · Canada (17) · Egypt (17) · South Korea (17) · United Kingdom (16) · Israel (15) · Pakistan (14) · France (12) · Russia (11) · India (10) · Germany (9)
Ping-I Hsu, Bachelor (5) · Taotao Liu, MD (5) · Xiuli Zuo, MD,PhD (5) · Hong Lu, M.D. (4) · Jyh-Chin Yang, M.D.Ph.D. (4) · Arie Levine, MD (3) · Ronald W Gottschalk, MD (3) · Caroline Mitchell, MD, MPH (2) · Feng-Woei Tsay, Bachelor (2) · Hong Lu, M.D.,Ph.D. (2)
PMID 33197289, PMID 30061279, PMID 36748942, PMID 29912399, PMID 30221827, PMID 32602065, PMID 37700689, PMID 20716255, PMID 26285807, PMID 28303587, PMID 40913503, PMID 10086658, PMID 10219875, PMID 10440607, PMID 10998650, PMID 11171619, PMID 12039901, PMID 12787214, PMID 12841893, PMID 1298430, PMID 15028938, PMID 15276398, PMID 15840453, PMID 16227794, PMID 16303068, PMID 16522393, PMID 16553634, PMID 16875654, PMID 17267841, PMID 17854602, PMID 17978109, PMID 18446147, PMID 18570578, PMID 18724841, PMID 18724858, PMID 18839083, PMID 19298337, PMID 19538334, PMID 19588358, PMID 19664210, PMID 19788600, PMID 20151809, PMID 20215625, PMID 20307191, PMID 20383102, PMID 20447259, PMID 20507380, PMID 20525969, PMID 20645521, PMID 20670293
2019 (4), 2014 (3), 2025 (3), 2023 (2), 2015 (1), 2016 (1), 272201300019C-3-0-1 (1), 4UH3DE031129-02 (1), D43TW009340 (1), P30CA016672 (1), P50CA221707 (1), R01AI058033 (1), R01DE012108 (1), R01DE013796 (1), R01DE014242 (1)