217 completed, 93 unknown, 36 not yet recruiting, 24 recruiting. 171 Not applicable, 79 Phase 4, 64 Phase 2, 59 Phase 3, 33 Phase 1.
Follow Hyaluronic Acid: new trials by email Literature Review of Hyaluronic Acid trials Research Report on Hyaluronic Acid
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Verification of the Efficacy/Safety of the Mixed Drug Injectable Delivery Vehicle for Treating Intractable Hearing Loss Dexamethasone, Hyaluronic acid, Indocyanine green(ICG) - Hearing Loss, Sensorineural, Hearing Loss, Sudden | Phase 1 / Phase 2 | Withdrawn | Seoul National University Hospital | 2026-12-15 | 2026-05-22 | |
| Clinical Evaluation of TrHCROSS® for Different Joints TrHCROSS®, Monovisc - Joint Osteoarthritis, Knee Osteoarthristis | Not applicable | Not yet recruiting | i+Med S.Coop. | 150 | 2026-12-01 | 2026-10-13 |
| Hyaluronic Acid vs I-PRF With Microneedling in Enhancing Peri-implant Soft Tissue Hyaluronic Acid (HA), Platelet rich fibrin - Peri-implant Mucosa Thickness | Phase 2 / Phase 3 | Not yet recruiting | Ain Shams University | 42 | 2026-10-30 | 2026-08-17 |
| Orthobiological Therapies in Musculoskeletal Disorders PRP injection, Bone Marrow Concentrate (BMAC), Hyaluronic Acid (Viscosupplementation) - Musculoskeletal Diseases or Conditions | Early Phase 1 | Recruiting | PROREGEN | 300 | 2026-09-16 | 2026-09-17 |
| Blue®M Gel Versus Hyaluronic Acid for Stability of Immediately Loaded Dental Implants Blue®M Gel, Hyaluronic Acid - Dental Implants, Immediate Dental Implant Loading | Not applicable | Not yet recruiting | Mansoura University | 24 | 2026-09-12 | 2026-09-28 |
| Evaluation of the Effects of Injectable Platelet-Rich Fibrin and Hyaluronic Acid Treatments, Administered in Addition to Free Gingival Graft Therapy, on Clinical Healing. Free gingival graft, Free Gingival Graft with i-PRF, Free Gingival Graft with Hyaluronic Acid - Lack of Keratinized Tissue, Mucogingival Surgery | Not applicable | Not yet recruiting | Saglik Bilimleri Universitesi | 45 | 2026-09-01 | 2026-09-04 |
| Chronic Patellar Tendinopathy (PT)is Prevalent in Participants of Several Sports.A Three-arm, Single-blind Randomized Controlled Trial Will be Conducted. We Want to Compare the Clinical Effectiveness of ESWT Alone, ESWT Combined With Hyaluronic Acid, and ESWT Combined With PRP in Athletes With PT Extracorporeal Shock Wave Therapy, Hyaluronic Acid (HA), Platelet-Rich Plasma - Chronic Patellar Tendinopathy | Not applicable | Active not recruiting | Chang Gung Memorial Hospital | 45 | 2026-09-01 | 2026-09-15 |
| Hyaluronic Acid Combined With Xenograft Versus Xenograft Alone in Immediate Implant Placement Immediate implant placement, Xenograft, Hyaluronic Acid (0.2%) - Immediate Implant Placement in the Esthetic Zone, NON-RESTORABLE TOOTH IN ESTHETIC ZONE | Not applicable | Not yet recruiting | Cairo University | 12 | 2026-09-01 | 2026-10-07 |
| Sodium Hyaluronate for Myofascial Thoracic Pain Sodium Hyaluronate Injection, Saline Injections - Thoracic Pain, Back Pain | Not applicable | Not yet recruiting | EPC Education s.r.o. | 100 | 2026-08-31 | 2026-08-20 |
| Research Title: Long Term Functional Outcome of a Single Hyaluronic Acid Injection in Improving Symptoms and Function in Patients With Knee Osteoarthritis - A Single-Arm Open-Label Study (DIART ONE). Hyaluronic Acid (HA) - Osteo Arthritis of the Knee | Phase 3 | Not yet recruiting | Universiti Sains Malaysia | 62 | 2026-08-30 | 2026-07-30 |
| Phase II/III Randomized Trial of UC-MSC Secretome vs Sodium Hyaluronate in Knee Osteoarthritis UC-MSC-Derived Secretome, Sodium Hyaluronate (Hyalein) - Knee Osteoarthritis (Knee OA) | Phase 2 / Phase 3 | Not yet recruiting | Universitas Sriwijaya | 50 | 2026-08-30 | 2026-05-12 |
| Autologous Serum Tears With Hyaluronate vs Balanced Salt Solution for Moderate-to-Severe Dry Eye Autologous Serum Tears (50% Autologous Serum Tears + 0.2% Sodium Hyaluronate), Biological - Autologous Serum Tears (50% Autologous Serum Tears + Balanced Saline Solution (BSS), Standard of Care (SOC) Treatment - Dry Eye, Eye Diseases | Phase 2 | Recruiting | University of Miami | 20 | 2026-07-21 | 2026-07-24 |
| Clinical Efficacy of Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Combined With Sodium Hyaluronate Intravesical Instillation in the Treatment of Radiation Cystitis Exosomes (hUC-MSC-Exo), Sodium Hyaluronate (Hyalein), Normal Saline (0.9% NaCl) - Radiation Cystitis | Early Phase 1 | Not yet recruiting | Fujian Medical University Union Hospital | 48 | 2026-07-20 | 2026-07-08 |
| Super Putty C-PRF/ Hyaluronic Acid Combination vs C-PRF in Gingival Phenotype Modification in Subjects With Thin Gingival Phenotype C-PRF and Hyaluronic Acid, C-PRF - Thin Gingival Phenotype | Not applicable | Not yet recruiting | Sajjad Ahmed Shakir | 20 | 2026-07-01 | 2026-07-02 |
| Effect of EGCG, Folic Acid, Vitamin B12 and Hyaluronic Acid on HPV DNA Integration Epigallocatechin gallate (EGCG), Folic Acid (FA), Vitamin B12 (B12), and Hyaluronic Acid (HA) - HPV Infection, HPV Integration | Not applicable | Not yet recruiting | IRCCS San Raffaele | 42 | 2026-07-01 | 2026-07-13 |
| Safety and Preliminary Efficacy of Endoscopic Submucosal Injection of Hyaluronic Acid Into the Bladder Wall in Patients With Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) Hyaluronic Acid (HA) - Cystitis, Interstitial, Chronic Pain | Phase 1 | Not yet recruiting | Sverdlovsk Regional Clinical Hospital No.1 | 15 | 2026-07-01 | 2026-06-25 |
| Intraarticular Injection of Botox and Hyaluronic Acid in Knee Osteoarthritis Hyaluronic acid, Botulinum toxin type A - Intraarticular Injection, Botox | Not applicable | Recruiting | Tanta University | 50 | 2026-06-24 | 2026-06-25 |
| Clinical Trial to Evaluate the Efficacy and Safety of Conjuran® After First and Second Cycle (Repeat) Administration in Patients With Knee Osteoarthritis Conjuran, Hyruan - Knee Osteoarthritis | Not applicable | Not yet recruiting | PharmaResearch Co.,Ltd | 180 | 2026-06-01 | 2026-06-12 |
| Guided Modified Socket Shield With Hyaluronic Acid for Black Triangle Management Guided socket shield without Hyaluronic acid, Guided socket shield with hyaluronic acid - Dental Implant Failed | Not applicable | Not yet recruiting | Kafrelsheikh University | 32 | 2026-05-10 | 2026-05-15 |
| Polynucleotides and Hyaluronic Acid vs Enamel Matrix Proteins in the Treatment of Intrabony Defects Regenerative periodontal surgery using Regenfast® (hyaluronic acid + polynucleotides) with Bio-Oss® graft, Regenerative periodontal surgery using Emdogain® (enamel matrix derivative) with Bio-Oss® graft - Periodontal Bone Loss, Periodontal Defect | Not applicable | Not yet recruiting | Shashi Dadlani | 40 | 2026-05-01 | 2026-05-15 |
Showing 20 of 392. Sign in to see all of them.
Osteoarthritis, Knee (78) · Osteoarthritis (50) · Dry Eye Syndromes (25) · Periodontitis (11) · Gingival Recession (7) · Pain (7) · Osteoarthritis, Hip (6) · Shoulder Pain (6) · Alveolar Bone Loss (5) · Bursitis (5) · Motor Activity (5) · Temporomandibular Joint Disorders (5) · Carpal Tunnel Syndrome (4) · Cystitis, Interstitial (4) · Rotator Cuff Injuries (4)
Cairo University (13) · Ain Shams University (9) · Assiut University (6) · Taipei Veterans General Hospital, Taiwan (6) · Galderma R&D (5) · Kaohsiung Veterans General Hospital. (5) · Mansoura University (5) · Taipei Medical University (5) · Hospital for Special Surgery, New York (4) · Samsung Medical Center (4) · The Cleveland Clinic (4) · Tri-Service General Hospital (TSGH) (4) · Al-Azhar University (3) · Chang Gung Memorial Hospital (3) · Damascus University (3)
United States (46) · Egypt (44) · Taiwan (31) · Turkey (Türkiye) (22) · China (21) · Italy (21) · South Korea (10) · Brazil (9) · Spain (9) · France (8) · Canada (7) · Israel (7) · Mexico (7) · Thailand (7) · Iraq (5)
Ru-Lan Hsieh, MD (4) · Shu-Fen Sun, MD (3) · Cesar Alejandro S Galeana, MD (2) · Elizaveta Kon, MD (2) · Giampietro Farronato, Professor (2) · Gianguido Cossellu, Fellow (2) · Philippe Kestemont, MD (2) · Ru-Lan Hsieh (2) · Sascha Colen, MD (2) · Yung-Tsan Wu, MD (2) · Abdullah I Ammoura, Researcher (1)
PMID 25238685, PMID 28146403, PMID 10328647, PMID 1058834, PMID 11276867, PMID 11516756, PMID 11702237, PMID 11759868, PMID 11859596, PMID 11989392, PMID 12140209, PMID 12593625, PMID 12620443, PMID 12622859, PMID 14121956, PMID 14502051, PMID 14508260, PMID 14705074, PMID 14723108, PMID 15455740, PMID 15655026, PMID 15703760, PMID 15767073, PMID 15976462, PMID 16029672, PMID 16900272, PMID 16905025, PMID 16973668, PMID 17068477, PMID 17172891, PMID 17205576, PMID 18476794, PMID 18691081, PMID 18902559, PMID 19034126, PMID 19248105, PMID 19722800, PMID 20166154, PMID 21080920, PMID 21248398, PMID 21323710, PMID 21529354, PMID 21829786, PMID 21852252, PMID 22142958, PMID 22169699, PMID 22441561, PMID 22545183, PMID 22672633, PMID 23018304
2009 (2), 2016 (1), 2019 (1), 2023 (1), K23AR050607 (1), R01HL081489 (1)