119 completed, 36 unknown, 15 recruiting, 10 not yet recruiting. 140 Not applicable, 15 Phase 2, 15 Phase 4, 8 Phase 3, 7 Phase 1.
Follow Root Planing: new trials by email Literature Review of Root Planing trials Research Report on Root Planing
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Alb-PRF as an Adjunct to Nonsurgical Periodontal Therapy Nonsurgical Periodontal Therapy, Albumin Platelet-Rich Fibrin - Periodontitis | Not applicable | Not yet recruiting | Halil Ata BIÇAKÇIOĞLU | 24 | 2026-12-01 | 2026-08-31 |
| Spirulina Gel in the Treatment of Periodontitis spirulina gel exracted by 1.5% calcium chloride (CaCl2) aqueous solution., conventional scaling and root planing - Periodontitis, Periodontitis Stage II | Not applicable | Not yet recruiting | Misr University for Science and Technology | 20 | 2026-10-30 | 2026-10-27 |
| Ozone Gel Versus Chlorohexidine Gel as an Adjunct to Non-Surgical Treatment of Stage II Periodontitis Grade B Among Smokers Patients Conventional scaling and root planing, Conventional scaling and root planing in addition to chlorhexidine gel, Conventional scaling and root planing in addition to ozone gel - Ozone Gel, Chlorohexidine Gel | Not applicable | Recruiting | October 6 University | 30 | 2026-09-01 | 2026-11-06 |
| Minimally Invasive Non-Surgical Periodontal Treatment Minimally Invasive Non-Surgical Therapy (MINST), Conventional Scaling and Root Planing - Periodontitis, Periodontitis (Stage 3) | Not applicable | Not yet recruiting | Ataturk University | 23 | 2026-08-01 | 2026-08-10 |
| Photodynamic Therapy as an Adjunct in Periodontal Treatment Scaling and Root Planing, Antimicrobial Photodynamic Therapy - Periodontitis, Periodontal Disease | Not applicable | Enrolling by invitation | Universidad Catolica Santiago de Guayaquil | 30 | 2026-07-28 | 2026-09-25 |
| Profiling Gingival Crevicular Fluid β-Catenin Level With 8-OHdG and Total Antioxidants Capacity During Healing of Periodontal Pockets: A 3-month Clinical Trial scaling and root planing - Periodontitis, Adult, Periodontal Diseases | Not applicable | Not yet recruiting | Zeyad Nazar | 21 | 2026-07-15 | 2026-05-19 |
| Hyaluronic Acid as an Adjunct to Non-Surgical Periodontal Therapy in Smokers Scaling and Root Planing, Hyaluronic Acid (HYADENT BG) - Hyaluronic Acid, Periodontal Therapy | Not applicable | Recruiting | Marmara University | 23 | 2026-07-13 | 2026-08-18 |
| NON-SURGİCAL PERİODONTAL THERAPY WİTH L-ARGİNİNE L-arginine 0.8% subgingival irrigation, Saline 0.9% subgingival irrigation (placebo), Scaling and root planing - Periodontal Disease, Periodontal Diseases | Not applicable | Active not recruiting | Alanya Alaaddin Keykubat University | 60 | 2026-06-01 | 2026-10-23 |
| Adjunctive Hyaluronic Acid Gel in Non-Surgical Periodontal Treatment of Patients With Diabetes Mellitus Scaling and root planing, Hyaluronic Acid (HYADENT BG) - Periodontitis, Diabetes Mellitus | Not applicable | Not yet recruiting | Marmara University | 23 | 2026-06-01 | 2026-06-08 |
| Periodontal Inflammation and Epigenetics in Obese Individuals Non-surgical periodontal therapy will be administered - Obesity, Periodontitis | Not applicable | Not yet recruiting | Louisiana State University Health Sciences Center in New Orleans | 40 | 2026-05-25 | 2026-05-28 |
| This a Clinical Trial to Evaluate the Efficacy of I-PRF, Povidone-Iodine and Laser as Adjuncts to Non-surgical Periodontal Treatment in Smokers and Non-Smokers Periodontitis Patients Injectable Platelet-Rich Fibrin (I-PRF), Diode Laser Activation, Povidone-Iodine Irrigation (1%) - Periodontitis, Smokers | Phase 4 | Recruiting | Military Hospital of Tunis | 50 | 2026-05-25 | 2026-07-16 |
| Effect of Periodontal Therapy on Asprosin in Stable Angina Non-surgical periodontal therapy (scaling and root planing), Non-surgical periodontal therapy (Professional dental cleaning) - Stable Angina Pectoris, Periodontitis | Not applicable | Completed | Ondokuz Mayıs University | 60 | 2026-05-20 | 2026-10-27 |
| Effects of Periodontal Treatment Associated With Antimicrobial Photodynamic Therapy on Halitosis in Patients With Diabetes Mellitus Scaling and root planing, Photodynamic Therapy with Conventional Methylene Blue - Type 2 Diabetes, Halitosis | Not applicable | Recruiting | University of Sao Paulo | 32 | 2026-04-02 | 2026-03-16 |
| Effectiveness of Epigallocatechin-3-Gallate (Green Tea Extract) as Adjunctive Locally Delivered Nanotherapeutic in the Treatment of Stage II Periodontitis Ten patients with stage II periodontitis will receive epigallocatechin-3-gallate (EGCG)-loaded chitosan nanoparticulate gel injected into the periodontal pockets, chitosan nanoparticulate gel (CTN gel), scaling and root planing (SRP) only. - Peridontitis | Phase 1 | Recruiting | Mansoura University | 30 | 2026-03-16 | 2026-08-10 |
| Effects of Non-Surgical Periodontal Treatment on Inflammatory and Bone Markers in Periodontitis Patients Scaling and Root Planing (SRP) - Periodontitis (Stage 3) | Not applicable | Active not recruiting | Saglik Bilimleri Universitesi | 56 | 2026-03-15 | 2026-04-27 |
| Non-Surgical Periodontal Therapy and Cardiac Biomarkers in Stable Angina Non-surgical periodontal therapy (scaling and root planing), Non-surgical periodontal therapy (Professional dental cleaning) - Stable Angina, Periodontitis | Not applicable | Completed | Ondokuz Mayıs University | 60 | 2026-02-20 | 2026-10-27 |
| Effect of Arestin-Enhanced SRP on Periodontal and Glycemic Outcomes in Diabetics local antibiotic application of topical minocycline, Scaling and Root Planing - Periodontitis, Diabetes Mellitus Type 2 | Early Phase 1 | Recruiting | Case Western Reserve University | 42 | 2026-02-06 | 2026-02-19 |
| Injectable PRF in Non-Surgical Periodontal Treatment Injectable Platelet-Rich Fibrin (i-PRF)., Scaling and Root Planing (SRP). - Periodontitis, Periodontal Pocket | Not applicable | Completed | Al-Mustansiriyah University | 18 | 2026-01-29 | 2026-10-07 |
| Injectable Platelet-Rich Fibrin (i-PRF) and Oxygen-Releasing Gel in the Treatment of Stage II Periodontitis. Injectable Platelet-Rich Fibrin (i-PRF, Peroxoborate Oxygen-Releasing Oral Gel, Scaling and Root Planing (SRP) - Stage III Periodontitis | Phase 1 / Phase 2 | Completed | Assiut University | 24 | 2026-01-20 | 2026-11-12 |
| Effect of Morus Nigra Mouthwash on Gingivitis Treatment Scaling and Root Planing, Morus Nigra Mouthwash - Gingivitis | Not applicable | Completed | Inonu University | 30 | 2026-01-15 | 2026-11-04 |
Showing 20 of 196. Sign in to see all of them.
Periodontitis (113) · Chronic Periodontitis (50) · Periodontal Diseases (49) · Diabetes Mellitus, Type 2 (10) · Gingivitis (9) · Periodontal Pocket (9) · Smoking (8) · Diabetes Mellitus (7) · Inflammation (7) · Cardiovascular Diseases (5) · Obesity (5) · Aggressive Periodontitis (4) · Alveolar Bone Loss (4) · Arthritis, Rheumatoid (3) · Angina, Stable (2)
Postgraduate Institute of Dental Sciences Rohtak (10) · Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre (6) · Ataturk University (5) · Mansoura University (4) · Marmara University (4) · Meenakshi Ammal Dental College and Hospital (4) · University of Baghdad (4) · University of Pisa (4) · University of Sao Paulo (4) · Alexandria University (3) · Assiut University (3) · Aydin Adnan Menderes University (3) · Belén Retamal-Valdes (3) · Cairo University (3) · Inonu University (3)
Turkey (Türkiye) (30) · United States (23) · Egypt (20) · India (20) · Brazil (15) · Italy (8) · Spain (6) · Canada (4) · Iraq (4) · Colombia (3) · Vietnam (3) · Germany (2) · Saudi Arabia (2) · Sweden (2) · United Arab Emirates (2)
Filippo Graziani, DDS, PhD (3) · Gaetano Isola (3) · Magda Feres, Professor (3) · Maha R. Taalab, PhD (2) · Nagihan Bostanci (2) · Sena Altintas, DDS (2) · A R Pradeep, MDS (1) · Ahmed Mortada Fikry, professor (1) · Ahmet C Talmac, PhD (1) · Ajay Mahajan, MDS (1) · Alex N Haas, PhD (1) · Aliaa Gamaleldin Aboulela, PhD (1) · Alparslan Dilsiz, Professor (1) · Alpiste Illueca Francisco, Professor (1)
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R01DE014242 (1), R21DE020916 (1), UL1RR024148 (1)