599 completed, 217 unknown, 81 not yet recruiting, 58 recruiting. 669 Not applicable, 64 Phase 2, 61 Phase 3, 44 Phase 4, 30 Phase 1.
Follow Dental Caries: new trials by email Literature Review of Dental Caries trials Research Report on Dental Caries
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effect of Bitewing Radiography on Outcomes and Costs of Treating Caries in Permanent Teeth Visual-tactile caries examination, Visual-tactile caries examination and bilateral bitewing radiography - Dental Caries, Teeth Loss | Not applicable | Not yet recruiting | Jukka Leinonen | 250 | 2027-03-01 | 2026-10-20 |
| Clinical Performance of High Viscous Glass Ionomer Cervical Restorations With Silver-Modified Atraumatic Restorative Technique (SMART) Versus Conventional Treatment in Elderly Cancer Patients. (A 12-month Randomized Clinical Trial) Silver Diamine Fluoride (SDF, 38%), Conventional Tooth Preparation, High-Viscosity Glass Ionomer Cement - Dental Caries, Cervical Caries | Not applicable | Not yet recruiting | Cairo University | 30 | 2027-01-15 | 2026-10-19 |
| Effect of Hemostatic Agents on TheraCal PT Pulpotomy Success in Primary Molars 2.5% Sodium Hypochlorite applied to pulpal tissue/stumps for 3 minutes to achieve hemostasis prior to TheraCal PT placement during primary molar pulpotomy and 15% Ferric Sulfate (Astringedent™ 15.5%) - Reversible Pulpitis, Dental Caries | Not applicable | Not yet recruiting | Reem Mohamed Gaber | 75 | 2027-01-01 | 2026-10-15 |
| Clinical and Radiographic Success of Calcium Hydroxide-Iodoform Paste Versus Modified Triple Antibiotic Paste for Necrotic Primary Molars in Children Calcium Hydroxide, Iodoform, paste, modified triple antibiotic paste - Dental Pulp Necrosis, Periapical Diseases | Not applicable | Not yet recruiting | Cairo University | 50 | 2027-01-01 | 2026-08-19 |
| Evaluation of Corrective Surgery Versus Dental Implants in Compromised Mandibular Molars hemi sectioning - Root Caries, Vertical Root Fracture | Not applicable | Not yet recruiting | Ain Shams University | 28 | 2027-01-01 | 2026-06-08 |
| Evaluation of Corrective Surgery Versus Dental Implants in Compromised Upper Molars root amputation - Root Caries | Not applicable | Not yet recruiting | Ain Shams University | 28 | 2027-01-01 | 2026-05-27 |
| Effectiveness of Toothpaste Tablets on Plaque, Gingival Health and Caries Experiences Toothpaste Tablet, Conventional Toothpaste - Gingival Inflammation, Dental Caries | Phase 3 | Not yet recruiting | Loma Linda University | 50 | 2026-12-01 | 2026-07-10 |
| Obesity and Oral Diseases in Adult Patients Lifestyle course., Bariatric surgery. - Obesity, Oral Diseases | Not yet recruiting | University of Bergen | 400 | 2026-11-01 | 2026-05-08 | |
| Clinical Performance of Two HEMA-Free Universal Adhesive Systems G2-Bond Universal, BeautiBond Xtreme Universal Adhesive - Cervical Caries | Not applicable | Not yet recruiting | Cairo University | 50 | 2026-11-01 | 2026-09-08 |
| Clinical Evaluation of Different Bulk-Fill Restorative Materials in Primary Molars Stela Capsule Bulk Fill Flowable Self-Cure Restorative, Filtek One Bulk Fill Restorative - Decayed Primary Molars, Decayed Tooth | Not applicable | Not yet recruiting | Burak Carıkcıoglu | 70 | 2026-10-30 | 2026-10-09 |
| Powered vs Manual Toothbrush Use: Its Effect on Caries Risk in Pre-Adolescents Powered toothbrush - Caries Risk, Caries, Dental | Not applicable | Recruiting | University of Michigan | 30 | 2026-10-28 | 2026-10-08 |
| Effects of GLP-1 Receptor Agonists on Saliva and Oral Health GLP-1 Receptor Agonists - Type 2 Diabetes, Obesity & Overweight | Not yet recruiting | Kırıkkale University | 50 | 2026-10-16 | 2026-09-14 | |
| A Comprehensive Oral Health Intervention Program for Preschool and Primary School Children in Suzhou Comprehensive Oral Health Intervention - Children, Dental Caries | Not applicable | Not yet recruiting | Soochow University | 2040 | 2026-10-08 | 2026-09-10 |
| Repair Versus Replacement of Failed Restorations in Primary Teeth Repair of Failed Restoration, Replacement of Failed Restoration - Dental Caries, Restoration Defects | Not applicable | Not yet recruiting | University of Sao Paulo | 382 | 2026-10-07 | 2026-09-21 |
| Artificial Intelligence (AI) for Proximal Caries Detection and Its Impact on Treatment Threshold Review of Radiograph Images - Caries,Dental | Not applicable | Recruiting | University of Michigan | 60 | 2026-10-05 | 2026-10-14 |
| The Relation Between Oral Hygiene and Microbial Load in the Oral Cavity After Restoring Primary Molars With Two Types of Ready-made Crowns stainless steel crown, bioflex crown - Carious Lesion, Ready-made Crowns | Recruiting | Al-Azhar University | 40 | 2026-10-05 | 2026-05-12 | |
| This Feasibility Study Will Evaluate the Study Protocols for Treatment and Follow-up Controls of Primary Molars With Caries in Children Treated With Stainless Steel Crowns or Conventional Fillings. Treatment Success and Potential Failures Will be Followed at 3, 6 and 12 Months Post Treatment. Stainless steel crowns, Conventional fillings - Dental Caries, Early Childhood Caries (ECC) | Not applicable | Not yet recruiting | Marie Norman | 100 | 2026-10-05 | 2026-10-20 |
| A Study to Evaluate the Cariostatic Efficacy of Nano Silver Fluoride (NSF) vs. Silver Diamine Fluoride (SDF) in Children Nano Silver Fluoride / NSF - Dental Caries | Not applicable | Recruiting | A.T. Still University of Health Sciences | 72 | 2026-10-01 | 2026-10-19 |
| A Clinical Study of KH001 for Pulp Preservation and Safety in Deep Dentin Caries KH001, Placebo - Dental Caries | Phase 2 | Not yet recruiting | Seoul National University Dental Hospital | 36 | 2026-09-30 | 2026-08-06 |
| Breaking the Cycle: Real-Time Family Oral Microbial Transmission Patterns as Intervention Targets Professional Dental Plaque Disruption - Dental Caries, Periodontitis | Not applicable | Not yet recruiting | University of Alberta | 225 | 2026-09-30 | 2026-06-30 |
Showing 20 of 1038. Sign in to see all of them.
Root Caries (39) · Dental Plaque (36) · Periodontal Diseases (33) · Gingivitis (27) · Periodontitis (18) · Disease (14) · Obesity (13) · Tooth Diseases (13) · Tooth Demineralization (12) · Behavior (10) · Plaque, Amyloid (10) · Van der Woude syndrome (10) · Dental Pulp Exposure (8) · Stomatognathic Diseases (8)
Stomatognathic Diseases (1030) · Tooth Demineralization (1026) · Tooth Diseases (1025) · Mouth Diseases (87) · Pathological Conditions, Signs and Symptoms (72) · Periodontal Diseases (49) · Behavior (44) · Infections (39) · Dental Deposits (36) · Pathologic Processes (36) · Signs and Symptoms (35) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (30) · Congenital Abnormalities (29) · Gingival Diseases (29)
silver diamine fluoride (28) · Sodium Fluoride (19) · Fluorides (12) · sodium fluoride topical preparation (10) · Dental Atraumatic Restorative Treatment (7) · Glass Ionomer Cements (7) · Probiotics (7) · chlorhexidine gluconate (7) · Bifluorid 12 (6) · Chlorhexidine (6) · Health Education, Dental (6) · Surveys and Questionnaires (6) · Toothbrushing (6) · Xylitol (6) · tricalcium silicate (6)
Cairo University (121) · University of Sao Paulo (31) · Hacettepe University (23) · Al-Azhar University (16) · The University of Hong Kong (16) · King Abdulaziz University (14) · University of California, San Francisco (14) · Ain Shams University (12) · Marmara University (11) · Solventum US LLC (10) · University of Copenhagen (10) · Dental Practice-Based Research Network (9) · Hadassah Medical Organization (9) · Mansoura University (9) · University of Campinas, Brazil (9)
United States (186) · Egypt (157) · Turkey (Türkiye) (107) · Brazil (78) · France (28) · China (23) · Denmark (19) · Italy (19) · United Kingdom (19) · Saudi Arabia (18) · Pakistan (16) · Sweden (16) · India (14) · Israel (13) · Chile (12)
Daniela P Raggio, Professor (5) · Gregg H Gilbert, DDS, MBA (5) · Mathilde C Peters, DMD, PhD (5) · Peter Milgrom, DDS (5) · Suchitra Nelson, PhD (4) · Annahita Ghassemi, PhD (3) · Edward CM Lo, BDS, PhD (3) · Francisco Ramos-Gomez, DDS, MS, MPH (3) · John Pittaway, DMD (3) · Livia MA Tenuta, PhD (3) · Margherita Fontana, DDS, PhD (3) · Mariana M Braga, PhD (3) · Parthasarathy Madurantakam, DDS, PhD (3)
PMID 20932395, PMID 10343087, PMID 12218274, PMID 1452871, PMID 1592970, PMID 16211157, PMID 17518963, PMID 18434577, PMID 19365118, PMID 22257664, PMID 23190278, PMID 23640952, PMID 25045768, PMID 25634162, PMID 25677244, PMID 25905656, PMID 31839988, PMID 33514787, PMID 34083157, PMID 35656656, PMID 10212363, PMID 1053919, PMID 1054935, PMID 10709851, PMID 10717828, PMID 10895619, PMID 10901411, PMID 10925773, PMID 11139785, PMID 11168468, PMID 11199555, PMID 11310134, PMID 11321382, PMID 11409642, PMID 11442730, PMID 1157366, PMID 11656783, PMID 11699977, PMID 1170757, PMID 11733293, PMID 11799281, PMID 11875603, PMID 12073723, PMID 12080313, PMID 12436828, PMID 12532056, PMID 12685620, PMID 12723166, PMID 12767443, PMID 12873775
U01DE016747 (7), D43TW007768 (2), K23DE023579 (2), 1UG3DE029443-01 (1), 2014 (1), 2017 (1), 2025 (1), 4UH3DE025492-03 (1), 4UH3DE030856-03 (1), D43TW010543 (1), R01DE012215 (1), R01DE013534 (1), R01DE014185 (1), R01DE014403 (1), R01DE025832 (1)