79 completed, 19 unknown, 14 recruiting, 9 not yet recruiting. 109 Not applicable, 8 Phase 2, 4 Phase 1, 4 Phase 3, 3 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Plasmonic PhotoThermal Therapy (PPTT) With Glucose-Coated Gold Nanoparticles (TSK-001) in Patients With Nodular Basal Cell Carcinoma (nBCC) TSK-001. Injectable solution of glucose-functionalised plasmonic gold nanoparticles (0.3 mg in 1 mL water for injection) for intratumoural administration., 808 nm near-infrared (NIR) diode laser (Hyper Diode 808) - Nodular BCC | Not applicable | Not yet recruiting | Torskal SAS | 78 | 2026-10-01 | 2026-10-23 |
| EFFICACY OF BIOMIN FLUORIDE VERSUS SODIUM FLUORIDE VARNISHES, WITH AND WITHOUT DIODE LASER ON WHITE SPOT LESIONS REMINERALIZATION IN PRIMARY TEETH. BioMin® fluoride varnish: 5% NaF varnish incorporating bioactive glass (calcium/phosphate releasing)., (BioMin® + Diode Laser), (Duraphat varnish + Diode laser) - White Spot Lesions [Initial Caries] on Smooth Surface of Tooth | Not applicable | Recruiting | Yassmin Mohamed | 80 | 2026-10-01 | 2026-09-30 |
| Evaluation of Different Non-Invasive Methods in the Treatment of Dentin Hypersensitivity Associated With Non-Carious Cervical Lesions: A Split-Mouth Clinical Study D Blue Diode Laser, ProSylc Bioactive Glass Powder - Non-Carious Cervical Lesions (NCCLs), Dentin Hypersensitivity | Not applicable | Not yet recruiting | Cukurova University | 30 | 2026-07-20 | 2026-06-15 |
| Clinical Evaluation of Microneedling Technique With Topical Application of Silymarin on Gingival Hyperpigmentation in Comparison With Diode Laser and Scalpel Methods. Gingival Depigmentation with Conventional Method, Gingival Depigmentation with Diode Laser, Gingival Depigmentation with Microneedling and Silymarin Application - Gingival Pigmentation, Gingival Hyperpigmentaion | Not applicable | Recruiting | Fayoum University | 30 | 2026-07-01 | 2026-02-13 |
| Micro-osteoperforation Versus Photobiomodulation Therapy for Accelerating Maxillary Canine Retraction Micro-osteoperforation (MOP), Photobiomodulation Therapy using 976 nm Diode Laser, Conventional orthodontic canine retraction - Malocclusion, Orthodontic Tooth Movement | Not applicable | Not yet recruiting | Kufa University | 75 | 2026-07-01 | 2026-06-18 |
| Nd:YAG Laser Combined With Injection Sclerotherapy Versus Diode Laser in the Treatment of Reticular Veins and Telangiectasias Using CLaCS Technique Nd:YAG laser, Diode laser - Nd:YAG Laser, Sclerotherapy | Not applicable | Recruiting | Ain Shams University | 80 | 2026-06-01 | 2026-07-01 |
| High-intensity Laser Therapy Versus Low Level Laser Therapy in the Treatment of Trigeminal Neuralgia 1064 nm Nd-YAG Laser, 940 nm Diode laser - Trigeminal Neuralgia | Not applicable | Not yet recruiting | Alexandria University | 38 | 2026-05-15 | 2026-05-15 |
| Effect of Diode Laser, Gudmar and Vinegar in Diabetic Patients During Root Canal Treatment 940 nm diode laser, apple cider vinegar, Gymnema Sylvestre - Diabete Type 2 | Not applicable | Recruiting | Sharda University | 90 | 2026-05-01 | 2026-05-28 |
| Diode Laser-Assisted Periodontal Therapy in Kidney Transplant Recipients Scaling and Root Planing, Diode Laser - Periodontitis, Kidney Transplant Recipients | Not applicable | Recruiting | Military Hospital 103 | 80 | 2025-12-09 | 2026-04-16 |
| Photobiomodulation, Photodynamic Therapy, and Clobetasol in the Treatment of Oral Lichen Planus. Photobiomodulation using 635 nm diode laser, Photodynamic therapy - laser mucosal treatment, Clobetasol propionate 0.05 percent topical application - Oral Lichen Planus, Erosive Lichen Planus | Not applicable | Recruiting | Medical University of Silesia | 60 | 2025-12-01 | 2026-04-30 |
| Evaluation Of Laser Versus Conventional Pulpotomies In Mature Molar Teeth With Irreversible Pulpitis Diode laser, Sodium Hypochlorite Solution - Irreversible Pulpitis (Toothache) | Not applicable | Recruiting | Rana Hegaz | 60 | 2025-11-07 | 2025-12-17 |
| 1726-nm Diode Laser for Lip Fordyce Spots Accure 1726-nm Diode Laser - Fordyce Spots | Not applicable | Recruiting | Venus Research Center | 20 | 2025-11-01 | 2025-12-26 |
| Comparison of the Efficacy of Clobetasol Propionate 0.05% Mouthwash, Photobiomodulation, and Their Combination in Managing of Oral Lesions in Patient With Pemphigus Vulgaris. Clobetasol propionate 0.05% Mouthwash, diode laser for photobiomodulation, clobetasol propionate 0.05% mouthwash + photobiomodulation - Oral Lesions in Patients With Pemphigus Vulgaris | Not applicable | Recruiting | Damascus University | 30 | 2025-11-01 | 2026-06-11 |
| Evaluation of the Effects of Different Irrigation Solutions and Activation Methods on Postoperative Pain and Quality of Life in Root Canal Treatment Irrigation with Sodium Hypochlorite and Conventional Syringe, Irrigation with Sodium Hypochlorite and EDDY, Procedure: Irrigation with Sodium Hypochlorite and Diode Laser - Irreversible Acute Pulpitis, Root Canal Treatment | Not applicable | Active not recruiting | Ankara Yildirim Beyazıt University | 90 | 2025-11-01 | 2025-11-21 |
| The Efficiency of 810 nm Diode Laser on Periapical Healing After Root Canal Retreatment diode laser, Calcium Hydroxide (Ca(OH)2) - This Study Will be Performed to Evaluate the Efficiency of 810 nm Diode Laser Disinfection on Periapical Healing in Root Canal Retreatment Cases | Not applicable | Recruiting | Al-Azhar University | 40 | 2025-09-19 | 2025-09-30 |
| Comparative Efficacy of Laser Systems and Fluoride in Managing Dentinal Hypersensitivity: RCT Erbium laser (2940 nm): Infrared light energy, Diode laser (650 nm): Visible red light energy, Fluoride varnish - Dentin Sensitivity, Dentine Hypersensitivity, Tooth Sensitivity | Not applicable | Not yet recruiting | Cairo University | 96 | 2025-09-01 | 2025-08-26 |
| Evaluation of the Systemic Burden of Non-surgical Periodontal Therapy: A Randomized Clinical Trial on Five Different Treatment Protocols Scaling and Root Planing, antibiotic prophylaxis, 810nm Diode Laser - Periodontitis | Not applicable | Recruiting | National and Kapodistrian University of Athens | 75 | 2025-08-25 | 2025-09-04 |
| Phentolamine Mesylate vs. Diode Laser for Anaesthesia Reversal OraVerse Injectable Product, diode laser - Reversal of Local Anesthesia in Children | Phase 3 | Completed | sara nabil | 36 | 2025-08-10 | 2026-10-16 |
| Post-operative Pain After Different Irrigation and Disinfection Methods in Single-rooted Teeth EDDY sonic irrigation system, EndoActivator (EA) sonic irrigation system, 980-nm diode laser - Post Operative Pain, Apical Periodontitis | Not applicable | Completed | Biruni University | 80 | 2025-08-10 | 2026-01-12 |
| Evaluating Postoperative Pain and Antibacterial Effect of Ultrasonic and 980 nm Diode Laser Combination diode laser, conventional irrigation, Diode laser - Post Operative Pain | Not applicable | Recruiting | Al-Azhar University | 120 | 2025-08-03 | 2026-03-17 |
Showing 20 of 129. Sign in to see all of them.
Periodontitis (10) · Periodontal Diseases (8) · Pain, Postoperative (7) · Dentin Sensitivity (6) · Pain (4) · Chronic Periodontitis (3) · Periapical Diseases (3) · Acne Vulgaris (2) · Agnosia (2) · Hypertrophy (2) · Lichen Planus, Oral (2) · Peri-Implantitis (2) · Periapical Periodontitis (2) · Temporomandibular Joint Disorders (2) · Tooth, Nonvital (2)
Cairo University (8) · Al-Azhar University (7) · Ain Shams University (6) · Hams Hamed Abdelrahman (5) · Alexandria University (4) · Venus Concept (4) · Fayoum University (3) · Krishnadevaraya College of Dental Sciences & Hospital (3) · University of Medicine and Pharmacy at Ho Chi Minh City (3) · Biruni University (2) · Faculty of Dental Medicine for Girls (2) · Hacettepe University (2) · Institut Curie (2) · Marmara University (2) · T.C. Dumlupınar Üniversitesi (2)
Egypt (38) · Turkey (Türkiye) (11) · United States (8) · India (6) · Vietnam (6) · Brazil (4) · Iraq (4) · France (3) · Italy (3) · Pakistan (3) · Spain (3) · China (2) · Jordan (2) · Poland (2) · United Arab Emirates (2)
Ahu Uraz, PhD Dr (2) · Ehab Hassanien, PhD (2) · Jeffery Kenkel, MD (2) · Maram Obeid, PhD (2) · Mauro P Santamaria, PhD (2) · Suzanne Kilmer, MD (2) · Abdullah Cevdet Akman, professor (1) · Abeer Aljoujou, PhD In Oral medicine (1) · Ahmed F. Assistant Professor, PhD (1) · Akanksha Dubey, MDS (1) · Amna N Khan, MPhil (1)
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