Chronic Disease: Clinical Trials

10746 completed, 2663 unknown, 1747 recruiting, 1417 terminated. 5464 Not applicable, 3690 Phase 2, 2451 Phase 1, 1959 Phase 3, 1488 Phase 4.

By phase and status

Phase	Trials	Status
Not applicable	5464	Completed 3000, Unknown 912, Recruiting 563, Terminated 300, Not yet recruiting 299, Active not recruiting 199, Withdrawn 131, Enrolling by invitation 44, Suspended 16
Phase 2	3690	Completed 2196, Terminated 463, Unknown 299, Recruiting 291, Active not recruiting 179, Withdrawn 150, Not yet recruiting 87, Enrolling by invitation 15, Suspended 10
Phase 1	2451	Completed 1497, Terminated 324, Recruiting 191, Unknown 157, Active not recruiting 114, Withdrawn 98, Not yet recruiting 53, Suspended 9, Enrolling by invitation 8
Phase 3	1959	Completed 1304, Unknown 179, Terminated 178, Recruiting 123, Active not recruiting 73, Withdrawn 54, Not yet recruiting 37, Enrolling by invitation 7, Suspended 4
Phase 4	1488	Completed 881, Unknown 287, Terminated 103, Recruiting 74, Withdrawn 65, Not yet recruiting 38, Active not recruiting 34, Enrolling by invitation 4, Suspended 2
Early Phase 1	149	Completed 59, Unknown 25, Recruiting 23, Terminated 15, Withdrawn 9, Not yet recruiting 8, Active not recruiting 7, Enrolling by invitation 2, Suspended 1

Follow Chronic Disease: new trials by email Literature Review of Chronic Disease trials Research Report on Chronic Disease

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
MRI Technical Development and Applications in Kidney Disease Chronic Kidney Diseases, Kidney Transplantation		Not yet recruiting	University of Minnesota	180	2028-06-30	2026-04-13
Safety and Outcomes of MUSE Stem Cell Therapy in Individuals With Traumatic Brain Injury MUSE Stem Cell Therapy - Traumatic Brain Injury, Traumatic Brain Injury (TBI) Patients		Not yet recruiting	Healing Hope International	10	2028-01-01	2026-03-10
Veteran Centered Meal Intervention in Chronic Kidney Disease Medically tailored meals (MTMs) - Chronic Kidney Disease	Not applicable	Not yet recruiting	VA Office of Research and Development	100	2027-10-01	2026-09-03
Technology-enabled Social Network Intervention to Increase Live Donor Kidney Transplantation Digital education outreach intervention for kidney transplant access and human guide, Digital education outreach intervention for kidney transplant access only (unguided) - End-Stage Renal Disease, Chronic Kidney Diseases	Not applicable	Not yet recruiting	State University of New York at Buffalo	550	2027-10-01	2026-10-20
Developing an Intervention to Optimize Virtual Care Adoption for COPD Management VC-OPTIONS - Chronic Obstructive Pulmonary Disease	Not applicable	Not yet recruiting	VA Office of Research and Development	40	2027-09-02	2026-09-29
Intermittent Fasting for Pancreatitis Intermittent Fasting, No intermittent fasting - Pancreatitis, Pancreatitis, Acute	Not applicable	Not yet recruiting	H. Lee Moffitt Cancer Center and Research Institute	64	2027-09-01	2026-09-17
Anti-Interleukin-6 (IL6) in Calciphylaxis Tocilizumab - Calciphylaxis	Phase 1	Not yet recruiting	Boston Medical Center	10	2027-09-01	2026-07-16
Zanubrutinib and Sonrotoclax for the Treatment of Relapsed Chronic Lymphocytic Leukemia /Small Lymphocytic Leukemia, ZeuS-2 Trial Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - Recurrent Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma	Phase 2	Not yet recruiting	City of Hope Medical Center	44	2027-08-04	2026-09-10
Remote Intervention Versus Routine Monitoring in COPD Patients With Chronic Hypercapnia Receiving Home Non-invasive Respiratory Support Remote Management, Remote Monitoring Only - COPD (Chronic Obstructive Pulmonary Disease), Acute Exacerbation of COPD	Not applicable	Not yet recruiting	Sir Run Run Shaw Hospital	236	2027-08-01	2026-08-06
Adaptive Cell Phone Support (ACPS) Adaptive Cell Phone Support, Computer-Delivered Cell Phone Support, Automated Text Reminders - Medication Adherence	Not applicable	Not yet recruiting	Children's Hospital Los Angeles	96	2027-08-01	2025-07-30
VR Pilot for Pancreatitis Gut Directed VR, Sham Control VR - Chronic Pancreatitis, Recurrent Pancreatitis	Not applicable	Not yet recruiting	Cedars-Sinai Medical Center	20	2027-07-22	2026-08-05
Trial Without Borders IMPLEMENT-CKD: IMPLEMENTation of Evidence-Based SGLT2i to Reduce Global Burden of Cardiovascular and Chronic Kidney Disease Implementation of recommendations - Implementation Research, Kidney Disease		Not yet recruiting	The University of Queensland	1390	2027-07-01	2026-10-02
RSV Vaccination to Reduce Recurrent AECOPD RSV vaccination (Arexvy, GlaxoSmithKline) - COPD, RSV	Phase 4	Not yet recruiting	Chinese University of Hong Kong	320	2027-07-01	2026-04-13
Lentiviral Gene Therapy for CGD Infusion of lentiviral TYF-CGD-modified autologous stem cells - Chronic Granulomatous Disease	Not applicable	Not yet recruiting	Shenzhen Geno-Immune Medical Institute	10	2027-07-01	2026-11-02
Sarcopenia in Chronic Kidney Disease (CKD) Patients Valine, EEA - Chronic Kidney Disease, Sarcopenia	Early Phase 1	Not yet recruiting	The University of Texas Health Science Center at San Antonio	20	2027-07-01	2026-11-02
cfMSC Stem Cell Therapy Targeting COPD clonal fetal MSCs - Chronic Obstructive Pulmonary Disease (COPD)	Phase 1 / Phase 2	Not yet recruiting	Shenzhen Geno-Immune Medical Institute	30	2027-06-30	2026-11-02
Phase III Clinical Trial of Hepalatide in Patients With Chronic Hepatitis D Hepalatide 2.1mg, Placebo of Hepalatide - Hepatitis D, Chronic	Phase 3	Not yet recruiting	Shanghai HEP Pharmaceutical Co., Ltd.	150	2027-06-01	2026-10-28
Kidney RISE: Randomized Integrated Supportive CarE Trial Kidney RISE - Chronic Kidney Disease (Stages 4 and 5)	Not applicable	Not yet recruiting	NYU Langone Health	280	2027-05-01	2026-08-03
Combined Versus Multicomponent Training in People With Chronic Kidney Disease Stages 3a and 3b Combined Training, Multicomponent Training - Chronic Kidney Disease Stage 3A, Chronic Kidney Disease Stage 3B	Not applicable	Not yet recruiting	University of Brasilia	57	2027-05-01	2026-10-30
Breakthrough - T1DM and Chronic Kidney Disease Tegoprubart, Islet Cell Transplant - Diabete Type 1, Chronic Kidney Disease	Phase 1 / Phase 2	Recruiting	University of Chicago	10	2027-04-29	2026-08-20

Showing 20 of 18796. Sign in to see all of them.

Narrower conditions

Pulmonary Disease, Chronic Obstructive (5335)  ·  Renal Insufficiency, Chronic (3080)  ·  Leukemia, Lymphocytic, Chronic, B-Cell (2019)  ·  Kidney Failure, Chronic (2002)  ·  Hepatitis C, Chronic (907)  ·  Precursor Cell Lymphoblastic Leukemia-Lymphoma (906)  ·  Leukemia, Myelogenous, Chronic, BCR-ABL Positive (878)  ·  Hepatitis B, Chronic (863)  ·  Leukemia (842)  ·  Lymphoma, Non-Hodgkin (820)  ·  Leukemia, Myeloid, Acute (812)  ·  Lymphoma, Follicular (721)  ·  Myelodysplastic Syndromes (691)  ·  Lymphoma, Mantle-Cell (679)

Broader conditions

Pathological Conditions, Signs and Symptoms (18794)  ·  Disease Attributes (18793)  ·  Pathologic Processes (18780)  ·  Respiratory Tract Diseases (6261)  ·  Lung Diseases (6045)  ·  Lung Diseases, Obstructive (5394)  ·  Urogenital Diseases (5053)  ·  Female Urogenital Diseases and Pregnancy Complications (4969)  ·  Female Urogenital Diseases (4960)  ·  Male Urogenital Diseases (4957)  ·  Urologic Diseases (4896)  ·  Kidney Diseases (4619)  ·  Renal Insufficiency (4475)  ·  Immune System Diseases (3957)

Interventions

Ribavirin (416)  ·  Cyclophosphamide (408)  ·  Rituximab (357)  ·  peginterferon alfa-2a (308)  ·  fludarabine phosphate (304)  ·  Tiotropium Bromide (242)  ·  fludarabine (206)  ·  Exercise (184)  ·  Mycophenolic Acid (182)  ·  Peripheral Blood Stem Cell Transplantation (179)  ·  Imatinib Mesylate (169)  ·  Tacrolimus (161)  ·  Cyclosporine (153)  ·  Busulfan (150)  ·  venetoclax (147)

Sponsors

GlaxoSmithKline (340)  ·  AstraZeneca (311)  ·  Novartis Pharmaceuticals (293)  ·  Boehringer Ingelheim (273)  ·  M.D. Anderson Cancer Center (241)  ·  National Cancer Institute (NCI) (211)  ·  Hoffmann-La Roche (196)  ·  Merck Sharp & Dohme LLC (154)  ·  Fred Hutchinson Cancer Center (133)  ·  Assiut University (125)  ·  Mayo Clinic (115)  ·  AbbVie (111)  ·  Gilead Sciences (109)  ·  VA Office of Research and Development (98)  ·  Bristol-Myers Squibb (89)

Countries

United States (6689)  ·  Germany (1516)  ·  China (1515)  ·  France (1483)  ·  United Kingdom (1442)  ·  Canada (1293)  ·  Spain (1109)  ·  Italy (1064)  ·  South Korea (686)  ·  Poland (660)  ·  Netherlands (639)  ·  Belgium (635)  ·  Australia (627)  ·  Taiwan (605)  ·  Turkey (Türkiye) (597)

Results publications

PMID 40576086, PMID 36005278, PMID 33511633, PMID 35018639, PMID 36791280, PMID 32499241, PMID 35224730, PMID 37916745, PMID 30739368, PMID 34515338, PMID 33586138, PMID 34495549, PMID 37870148, PMID 32390133, PMID 32943047, PMID 38189593, PMID 30977945, PMID 34398557, PMID 35815359, PMID 30012435, PMID 30923816, PMID 33283264, PMID 34164803, PMID 36472416, PMID 37542951, PMID 37651553, PMID 42149813, PMID 31568620, PMID 32588430, PMID 33782940, PMID 30529905, PMID 35235189, PMID 38018702, PMID 38620092, PMID 38770818, PMID 42551404, PMID 17507545, PMID 23524640, PMID 23620574, PMID 28427875, PMID 28835440, PMID 29377566, PMID 30885996, PMID 33107592, PMID 35514131, PMID 39423760, PMID 39963952, PMID 10377201, PMID 12091180, PMID 19720809

NIH funding

2023 (101), 2015 (84), 2009 (69), 2014 (68), 2025 (59), 2017 (57), P30CA015704 (56), 2016 (54), 2019 (54), 2018 (53), 2008 (41), P30CA006973 (33), P30CA033572 (33), P30CA015083 (31), 2005 (28)