804 completed, 253 unknown, 141 recruiting, 110 not yet recruiting. 900 Not applicable, 102 Phase 2, 49 Phase 3, 38 Phase 1, 38 Phase 4.
Follow this condition Literature Review of Jaw Diseases trials Research Report on Jaw Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy of Different Disinfection Technologies in Molar Non-Surgical Retreatment GentleWave System, Conventional rotary instrumentation with passive ultrasonic irrigation - Apical Periodontitis | Not applicable | Not yet recruiting | University of Alabama at Birmingham | 60 | 2027-07-01 | 2026-04-08 |
| Feasibility and Acceptability of OLP-EXP in Chronic Pain OLP-EXP, OLP, EXP - Temporomandibular Disorders (TMD) | Not applicable | Not yet recruiting | University of Maryland, Baltimore | 57 | 2027-07-01 | 2026-08-25 |
| Frankincense Versus Sodium Hypochlorite for Root Canal Disinfection Sodium hypochlorite 3%, Frankincense-based irrigant - Pulp Necrosis, Root Canal Infection | Early Phase 1 | Not yet recruiting | Oman Dental College | 30 | 2027-01-19 | 2026-09-22 |
| Clinical and Radiographic Success of Calcium Hydroxide-Iodoform Paste Versus Modified Triple Antibiotic Paste for Necrotic Primary Molars in Children Calcium Hydroxide, Iodoform, paste, modified triple antibiotic paste - Dental Pulp Necrosis, Periapical Diseases | Not applicable | Not yet recruiting | Cairo University | 50 | 2027-01-01 | 2026-08-19 |
| Multimodal Therapy for Somatosensory Tinnitus Multimodal physiotherapy for TMJ and Cervical spine, Combined Exercise Program (Aerobic + Resistance + Breathing), Tinnitus-Specific Psychological Support - Ear Noise, Tinnitus, Noise Induced | Not applicable | Not yet recruiting | Charles University, Czech Republic | 160 | 2027-01-01 | 2026-03-12 |
| Postoperative Assessment of Platelet-Rich Plasma and Platelet-Rich Fibrin in Temporomandibular Joint Surgery Temporomandibular Joint Disorders | Not yet recruiting | Jingping Wang, MD, Ph.D. | 700 | 2026-11-15 | 2026-06-09 | |
| Osteogenic Potential of Topical Metformin Gel on Cystic Jaw Defects For the Experimental Arm: 1% Metformin Gel, For the Comparator / Control Arm: Placebo Gel - Jaw Cysts, Metformin | Not applicable | Not yet recruiting | Fayoum University | 32 | 2026-10-30 | 2026-10-14 |
| R01_Pilot Jaw Muscle Phenotypes Local Heat Therapy - Chronic TMD Pain, Temporomandibular Disorder | Not applicable | Not yet recruiting | University of Minnesota | 10 | 2026-10-20 | 2026-10-02 |
| Machine Learning for Evaluating and Diagnosing Temporomandibular Disorders Low-Level Laser Acupuncture, Proprioceptive Training, Stabilization Splint Treatment - Temporomandibular Disorders (TMD), TMJ Disorder | Not applicable | Recruiting | En Chu Kong Hospital | 180 | 2026-10-09 | 2026-10-13 |
| Apical Periodontitis and Glycemic Control in Diabetic and Non-diabetic Egyptian Sub-population Apical Periodontitis | Not yet recruiting | Cairo University | 88 | 2026-10-05 | 2026-10-02 | |
| Endodontic Microsurgery Platelet rich fibrin - Apical Periodontitis | Phase 4 | Not yet recruiting | Mark Schachman | 20 | 2026-10-01 | 2026-07-29 |
| Comparison of Cervical and TMJ Parameters in Young Adults With and Without Text Neck Syndrome Text Neck Syndrome, Temporomandibular Joint Disorders | Not yet recruiting | Borna Farhoomand | 80 | 2026-10-01 | 2026-10-01 | |
| Effects of Orofacial Myofunctional Therapy and Cervical Stabilization Exercises in Patients With Axis-i Group Iia Temporomandibular Dysfunction Cervical Stabilization Exercises, Orofacial Myofunctional Therapy - Temporo-mandibular Dysfunction, Disc Displacement | Not applicable | Not yet recruiting | University of Lahore | 88 | 2026-10-01 | 2026-10-01 |
| Post-operative Pain and Apical Healing After Root Canal (re)Treatment With Laser-activated Irrigation Versus Sonic or no Activation sonically activated irrigation, laser activated irrigation, conventional needle irrigation - Apical Periodontitis, Post Operative Pain, Acute | Not applicable | Not yet recruiting | University Ghent | 183 | 2026-10-01 | 2026-10-20 |
| Ficerafusp Alfa, Pembrolizumab, and Stereotactic Body Radiotherapy (SBRT) for Head and Neck Squamous Cell Carcinoma (HNSCC) Hypofractionated Stereotactic Body Radiotherapy (SBRT), Pembrolizumab, Ficerafusp alfa - Head and Neck Squamous Cell Carcinoma, HPV-Negative Squamous Cell Carcinoma | Phase 1 / Phase 2 | Not yet recruiting | Washington University School of Medicine | 45 | 2026-09-30 | 2026-08-13 |
| Marine Lipids Ease Painful TMD SPM Precursor-Enriched Marine Lipid Supplement, Medium-Chain Triglyceride Supplement - Temporomandibular Disorder (TMD) | Not applicable | Not yet recruiting | University of North Carolina, Chapel Hill | 100 | 2026-09-25 | 2026-08-31 |
| Furlow With Buccinator and Fistula Formation furlow with buccinator, two flap palatoplasty - Cleft Palate | Not applicable | Not yet recruiting | Fayoum University | 20 | 2026-09-25 | 2026-09-25 |
| Spinal Mobility, Rigidity, and Kinesiophobia in PD and TMD PARKINSON DISEASE (Disorder), Rigidity | Recruiting | Mustafa Kemal University | 60 | 2026-09-23 | 2026-10-05 | |
| INNOVATIVE BENEFITS OF A 4D VIRTUAL SIMULATOR digital jaw impressions and Modjaw® records - Temporomandibular Disorders (TMD) | Not applicable | Recruiting | Centre Hospitalier Universitaire de Nice | 20 | 2026-09-17 | 2026-09-22 |
| Comparing Amla (Emblica Officinalis) and 3% Sodium Hypochlorite Against Enterococcus Faecalis in Root Canal Treatment. Sodium Hypochlorite 3% Solution, Emblica officinalis Solution - Pulp Necrosis, Apical Periodontitis | Not applicable | Not yet recruiting | Postgraduate Medical Institute, Lahore | 66 | 2026-09-17 | 2026-09-22 |
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Temporomandibular Joint Disorders (588) · Periapical Periodontitis (232) · Jaw, Edentulous (118) · Cleft Palate (114) · Jaw, Edentulous, Partially (75) · Pain (72) · Retrognathia (58) · Facial Pain (53) · Temporomandibular Joint Dysfunction Syndrome (53) · Pain, Postoperative (51) · Cleft Lip (47) · Periapical Diseases (45) · Dental Pulp Necrosis (39) · Basal Cell Nevus Syndrome (35) · Mouth, Edentulous (32)
Stomatognathic Diseases (1423) · Musculoskeletal Diseases (1148) · Mandibular Diseases (687) · Muscular Diseases (614) · Craniomandibular Disorders (612) · Joint Diseases (612) · Mouth Diseases (607) · Pathological Conditions, Signs and Symptoms (355) · Tooth Diseases (327) · Periodontal Diseases (306) · Signs and Symptoms (268) · Neurologic Manifestations (263) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (261) · Congenital Abnormalities (254)
Low-Level Light Therapy (27) · Occlusal Splints (24) · Musculoskeletal Manipulations (22) · Arthrocentesis (19) · Dental Implants (17) · Exercise (17) · Physical Therapy Modalities (15) · Calcium Hydroxide (14) · Botulinum Toxins, Type A (13) · Control Groups (12) · Dry Needling (11) · Saline Solution (11) · Exercise Therapy (9) · Sodium Chloride (9) · Hyaluronic Acid (8)
Cairo University (85) · Postgraduate Institute of Dental Sciences Rohtak (31) · Ain Shams University (24) · Dentsply Sirona Implants and Consumables (23) · Istanbul Medipol University Hospital (18) · Al-Azhar University (16) · University of Nove de Julho (16) · University of Sao Paulo (14) · Mansoura University (13) · Tanta University (12) · Assiut University (11) · Marmara University (11) · Alexandria University (10) · Fayoum University (10) · Hacettepe University (10)
Turkey (Türkiye) (257) · Egypt (202) · United States (181) · Spain (78) · Brazil (77) · Italy (51) · China (41) · France (38) · Belgium (33) · Germany (30) · India (30) · Poland (29) · Pakistan (28) · Sweden (27) · Canada (26)
Ervin Epstein, MD (5) · Johan Abeloos, MD (4) · Larissa Trojan, PhD (4) · Nieto Luis, Master (4) · Seyda Ersahan, Assoc.Prof. (4) · Aliye Kamalak (3) · Aysenur Tuncer (3) · Ehab Hassanien, PhD (3) · Maram F Obeid, Professor (3) · Maram Obeid, PhD (3) · Mattias Ulmner, DDS, PhD (3) · Mohamed K Allam, Ass prof (3) · Parthasarathy Madurantakam, DDS, PhD (3)
PMID 24482784, PMID 3457698, PMID 1298767, PMID 21238793, PMID 14651280, PMID 18018993, PMID 19345793, PMID 19696851, PMID 21194990, PMID 22318373, PMID 23028999, PMID 23593156, PMID 23672400, PMID 24158342, PMID 26250795, PMID 27009835, PMID 31735221, PMID 35866376, PMID 39115583, PMID 41914053, PMID 9477818, PMID 9520246, PMID 10029751, PMID 10337315, PMID 10371309, PMID 10371903, PMID 10864087, PMID 10883694, PMID 11005733, PMID 11033213, PMID 11105405, PMID 11168257, PMID 11199749, PMID 11381256, PMID 11393894, PMID 11408550, PMID 11575190, PMID 11782825, PMID 11842863, PMID 11871683, PMID 11873920, PMID 12010164, PMID 12164236, PMID 12182304, PMID 12196219, PMID 12202695, PMID 12424446, PMID 12435463, PMID 12513918, PMID 12555926
2023 (4), 2015 (2), 2025 (2), P50AT000076 (2), R01CA109584 (2), R21DC017553 (2), 2005 (1), 2008 (1), 2014 (1), K23DE020197 (1), K23DE031807 (1), P30CA124435 (1), P50DC007667 (1), R01DC011524 (1), R01DE010437 (1)