180 completed, 51 unknown, 35 recruiting, 22 not yet recruiting. 167 Not applicable, 17 Phase 4, 8 Phase 3, 6 Phase 2, 2 Early Phase 1.
Follow Peri-Implantitis: new trials by email Literature Review of Peri-Implantitis trials Research Report on Peri-Implantitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Reconstructive Treatment of Peri-implantitis With Electrolytic Decontamination Versus Titanium Brushes test device GalvoSurge, Mechanical decontamination with titanium brush - Peri-Implantitis and Peri-implant Mucositis | Early Phase 1 | Not yet recruiting | George Eastman Dental Hospital, Italy | 38 | 2027-01-01 | 2026-09-11 |
| Regenerative Outcomes for Peri-implant Bony Defects Using Amnion-chorion Barrier vs. Collagen Membrane BioXclude Amnion Chorion Membrane, Collagen Membrane - Peri-Implantitis | Not applicable | Not yet recruiting | Loma Linda University | 56 | 2026-12-01 | 2026-07-10 |
| Titanium Particle Release Across Non-Surgical Peri-implantitis Therapies Mechanical Debridement with Titanium Curettes, Mechanical Debridement with Plastic Curettes, 940 nm Diode Laser Decontamination - Peri-implantitis | Not applicable | Not yet recruiting | Saglik Bilimleri Universitesi | 70 | 2026-10-15 | 2026-09-10 |
| ATR-FTIR and Raman Spectroscopy of Peri-Implant Crevicular Fluid in Peri-Implantitis ATR-FTIR and Raman Spectroscopic Analysis of Peri-Implant Crevicular Fluid - Peri-Implantitis | Not yet recruiting | Necmettin Erbakan University | 100 | 2026-10-08 | 2026-10-07 | |
| Effect of Metallic Particles on the Progression of Peri-Implantitis Peri-implantitis | Not yet recruiting | University of Barcelona | 50 | 2026-10-01 | 2026-08-28 | |
| Timing of Success Evaluation After Flapless Treatment of Peri-Implantitis Flapless non-surgical treatment of peri-implantitis - Peri-implantitis | Not yet recruiting | University of Barcelona | 60 | 2026-10-01 | 2026-09-28 | |
| Patient Perspectives Throughout Peri-Implantitis Treatment Peri-implantitis | Not yet recruiting | University of Barcelona | 45 | 2026-09-03 | 2026-07-09 | |
| Access to Probing and Peri-implant Diseases Peri-implant probing - Peri-implantitis, Peri-implant Bone Loss | Recruiting | Arrow Development | 281 | 2026-09-01 | 2026-10-13 | |
| Evaluation of the Effects of Routine Phase I Periodontal Therapy on Clinical Parameters and Levels of Gremlin-1, CTHRC1, and Tenascin-C in Gingival Crevicular Fluid and Peri-Implant Sulcular Fluid in Individuals With Periodontitis and Peri-Implantitis Routine Phase I Non-Surgical Periodontal Therapy - Periimplantitis, Periodontitis | Not yet recruiting | Adiyaman University | 30 | 2026-09-01 | 2026-09-01 | |
| Comparison of Anesthetic Efficacy and Safety Between Inferior Alveolar Nerve Block and the Infiltrative Technique for the Treatment of Peri-implant Diseases in Posterior Mandibular Implants Comparison of anesthetic efficacy and safety between nerve block and infiltrative technique for periimplantitis surgical treatment in poosterior mandibular implants - Local Anesthesia, Dental Implants | Not applicable | Not yet recruiting | University of Barcelona | 30 | 2026-09-01 | 2026-05-22 |
| Implant Survival After Surgical Treatment of Peri-implantitis of Infra-bony Defects Reconstructive therapy - Peri-implantitis | Enrolling by invitation | University of Turin, Italy | 75 | 2026-09-01 | 2026-09-09 | |
| Electrolytic Surface Decontamination in the Surgical Treatment of Peri-implantitis: A Randomized Clinical Trial Electrolytic Surface Decontamination, Conventional Surgical Treatment - Peri-implantitis | Not applicable | Not yet recruiting | Istanbul University | 80 | 2026-08-01 | 2026-06-12 |
| Relationship Between Metrnl Expression, IL-1β, and TNF-α in Patients With Peri-Implantitis Peri-implantitis | Completed | Ataturk University | 68 | 2026-07-07 | 2026-09-03 | |
| Longitudinal Evaluation of Several Modalities of Treatment of Peri-implantitis: 5 to 23 Years Follow-up Periodontal Disease, Microbiology | Not yet recruiting | University of Guarulhos | 300 | 2026-06-29 | 2026-07-07 | |
| Occurrence of Peri-Implant Complications: A Multifactorial Cross-Sectional Study Dental implant - Peri-Implantitis and Peri-implant Mucositis | Recruiting | Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain | 150 | 2026-06-06 | 2026-06-10 | |
| Impact of Smoking on Immune Responses in Peri-implant Health and Disease Peri-Implant Health, Peri Implant Mucositis | Recruiting | Gazi University | 216 | 2026-06-01 | 2026-09-17 | |
| Crown Removal in Non-Surgical Peri-Implantitis Therapy: A Randomized Trial Non-Surgical Peri-Implant Therapy without Crown, Non-Surgical Peri-Implant Therapy with Crown - Peri-implantitis | Not applicable | Recruiting | G. d'Annunzio University | 36 | 2026-04-20 | 2026-05-07 |
| Long-term Stability of Peri-implantitis Treatments: a 3-year Clinical Evaluation Peri-implantitis | Completed | Ramón Pons Calabuig | 27 | 2026-04-01 | 2026-09-29 | |
| The Effect of Systemic Factors on Peri-implant Health Status and Clinical Indices Clinical and Radiographic Periodontal Assessment - Peri-implantitis, Dental Implants | Completed | Inonu University | 93 | 2026-03-11 | 2026-04-15 | |
| Adjunctive Keratinized Mucosa Augmentation in Peri-Implantitis Submucosal debridman + saline irrigation, Free gingival graft surgery - Peri-implantitis, Soft Tissue Augmentation at Dental Implants | Not applicable | Recruiting | Gazi University | 30 | 2026-03-01 | 2026-03-13 |
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Periodontitis (24) · Periodontal Diseases (21) · Alveolar Bone Loss (9) · Mucositis (9) · Inflammation (7) · Bone Diseases, Metabolic (6) · Smoking (6) · Dental Plaque (5) · Diabetes Mellitus (4) · Hypersensitivity (3) · Infections (3) · Patient Satisfaction (3) · Periodontal Pocket (3) · Bacterial Infections (2)
Stomatognathic Diseases (317) · Mouth Diseases (316) · Periodontal Diseases (297) · Pathological Conditions, Signs and Symptoms (20) · Bone Diseases (17) · Musculoskeletal Diseases (17) · Pathologic Processes (16) · Nutritional and Metabolic Diseases (14) · Behavior (12) · Metabolic Diseases (11) · Periodontal Atrophy (10) · Bone Resorption (9) · Digestive System Diseases (9) · Gastroenteritis (9) · Gastrointestinal Diseases (9)
Chlorhexidine (13) · Surgical Procedures, Operative (6) · Dental Implants (5) · Control Groups (4) · Metronidazole (4) · Observation (4) · Tooth Exfoliation (4) · Amoxicillin (3) · High-Energy Shock Waves (3) · Laser Therapy (3) · Lasers (3) · Lasers, Solid-State (3) · Minocycline (3) · Surveys and Questionnaires (3) · Crown Lengthening (2)
Universitat Internacional de Catalunya (15) · Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain (13) · Universidad Complutense de Madrid (8) · University of Michigan (7) · Università Vita-Salute San Raffaele (7) · Gazi University (6) · University of Barcelona (6) · Aristotle University Of Thessaloniki (5) · Göteborg University (5) · University of Oslo (5) · Kutahya Health Sciences University (4) · Necmettin Erbakan University (4) · University of Bern (4) · University of Guarulhos (4) · University of Pittsburgh (4)
Spain (50) · Turkey (Türkiye) (49) · United States (32) · Italy (29) · Sweden (21) · Brazil (11) · Egypt (10) · Switzerland (8) · Germany (7) · Greece (6) · Israel (6) · Norway (6) · China (5) · Canada (4) · France (4)
Tord Berglundh, Professor (4) · Massimo De Sanctis (3) · Ahmet Cemil Talmac, PhD (2) · Alberto Monje, DDS (2) · Andrea Ravida, DDS MS PhD (2) · Andrea Ravida, DDS, MS, PhD (2) · Annsofi Johannsen (2) · Aysegul Sari, PhD (2) · Damla Akbal, PhD (2) · Dicle Altindal, PhD (2) · Georgios Kotsakis, DDS, MS (2) · Heba Allah Madi Dr (2) · Hom-Lay Wang, DDS MSD PhD (2)
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