72 completed, 25 unknown, 14 recruiting, 8 not yet recruiting. 80 Not applicable, 12 Phase 2, 8 Phase 4, 7 Phase 1, 6 Phase 3.
Follow Periodontal Pocket: new trials by email Literature Review of Periodontal Pocket trials Research Report on Periodontal Pocket
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Alb-PRF as an Adjunct to Nonsurgical Periodontal Therapy Nonsurgical Periodontal Therapy, Albumin Platelet-Rich Fibrin - Periodontitis | Not applicable | Not yet recruiting | Halil Ata BIÇAKÇIOĞLU | 24 | 2026-12-01 | 2026-08-31 |
| Clinical Effectiveness of Oxygen-Releasing Oral Gel as an Adjunct to Scaling and Root Debridement in Patients With Severe Periodontal Pockets: A Randomized Clinical Trial Topical oxygen-releasing oral gel, No intervention - Periodontitis | Not applicable | Not yet recruiting | Universiti Sains Malaysia | 38 | 2026-11-01 | 2026-09-30 |
| Effect of Gingival Mesenchymal Stem Cell-Derived Small Extracellular Vesicles in Management of Infra-bony Periodontal Defect Gingival mesenchymal stem cell derived small extracellular vesicles, β-calcium triphosphate (β-TCP) + collagen membrane - Infra-bony Periodontal Defect | Phase 2 | Not yet recruiting | Ain Shams University | 22 | 2026-10-01 | 2026-10-15 |
| Dental Loupe Versus Dental Operating Microscope for Non-Surgical Periodontal Treatment Mechanical debridement and dental plaque sample collection with dental loupe, Mechanical debridement and dental plaque sample collection with dental microscope - Periodontitis, Periodontitis and Treatment Need | Not applicable | Recruiting | Saglik Bilimleri Universitesi | 30 | 2026-08-01 | 2026-09-21 |
| Influence of Acetal Resin Versus Nylon Elastic Cap on Crestal Bone Loss in Mandibular Implant-Supported Overdenture Acetal Resin, nylon - Bone Loss, Pocket, Periodontal | Not applicable | Not yet recruiting | Future University in Egypt | 22 | 2026-07-01 | 2026-06-24 |
| This a Clinical Trial to Evaluate the Efficacy of I-PRF, Povidone-Iodine and Laser as Adjuncts to Non-surgical Periodontal Treatment in Smokers and Non-Smokers Periodontitis Patients Injectable Platelet-Rich Fibrin (I-PRF), Diode Laser Activation, Povidone-Iodine Irrigation (1%) - Periodontitis, Smokers | Phase 4 | Recruiting | Military Hospital of Tunis | 50 | 2026-05-25 | 2026-07-16 |
| Periodontal Dressings in Non-Surgical Therapy Ora Aid application, Coe-Pack application - Periodontitis, Periodontitis (Stage 3) | Not applicable | Not yet recruiting | Saglik Bilimleri Universitesi | 25 | 2026-04-01 | 2026-03-16 |
| Non-Surgical Treatment of Periodontitis With Adjunctive Sodium Hypochlorite/Amino Acids and Cross-Linked Hyaluronic Acid Standard Non-Surgical Periodontal Therapy, tandard Therapy + Sodium Hypochlorite/Amino Acid Gel, Standard Therapy + Sodium Hypochlorite/Amino Acid Gel + Cross-Linked Hyaluronic Acid - Periodontitis | Not applicable | Not yet recruiting | Marwan El Mobadder | 78 | 2026-03-11 | 2026-03-17 |
| Regenerative Gel (Emdogain®) for Healing After Wisdom Tooth Extraction Enamel Matrix Derivative (Emdogain®) - Alveolar Bone Loss, Periodontal Pocket | Not applicable | Recruiting | Aristotle University Of Thessaloniki | 70 | 2026-03-09 | 2026-07-22 |
| Evaluation of Hyaluronic Acid and Chlorhexidine Gel as an Adjunct to Minimally Invasive Non-surgical Therapy in the Treatment of Stage III and IV Periodontitis MINST + CHX+HA gel, MINST - Periodontology, Periodontal Disease | Not applicable | Active not recruiting | Cairo University | 72 | 2026-03-01 | 2026-08-07 |
| Injectable PRF in Non-Surgical Periodontal Treatment Injectable Platelet-Rich Fibrin (i-PRF)., Scaling and Root Planing (SRP). - Periodontitis, Periodontal Pocket | Not applicable | Completed | Al-Mustansiriyah University | 18 | 2026-01-29 | 2026-10-07 |
| Adjunctive Diode Laser Therapy in Non-Surgical Periodontal Therapy LASER assisted SRP, RsD - Periodontal Disease, Periodontal Pockets | Not applicable | Recruiting | Tel Aviv University | 20 | 2026-01-01 | 2026-03-03 |
| Changes in Periodontal Pocket Depth After Periodontal Treatment Periodontal Treatment - Periodontitis | Not applicable | Completed | Necmettin Erbakan University | 24 | 2025-12-26 | 2026-10-21 |
| Occlusal Load Distribution and Periodontal Status Periodontal Diseases, Periodontal Pocket | Not yet recruiting | University of Bari Aldo Moro | 50 | 2025-10-01 | 2025-09-30 | |
| Hyaluronic Acid and Octenidine Gel as an Adjunct to Non-surgical Periodontal Treatment Hyaluronic Acid (HA) and Octenidine gel, Non-surgical periodontal treatment (NSPT) - Periodontitis, Wound Heal | Not applicable | Recruiting | Queen Mary University of London | 26 | 2025-06-03 | 2026-02-05 |
| The Efficacy of Salvia Officinalis Gel in the Treatment of Periodontitis CLINICAL TRIAL Salvia officinalis Gel - Periodontal Pocket | Not applicable | Not yet recruiting | University of Baghdad | 23 | 2025-05-01 | 2025-03-28 |
| Diode Laser as an Adjunct to Professional Mechanical Plaque Removal Professional mechanical plaque removal and Laser, Professional mechanical plaque removal - Periodontitis, Pocket, Periodontal | Not applicable | Active not recruiting | University of Sulaimani | 40 | 2025-01-01 | 2026-05-04 |
| Adjunctive Effect of Erythritol on Pocket Closure Rates Non-surgical periodontal therapy + sub-gingival air polishing, Non-surgical periodontal therapy alone - Periodontitis, Pocket, Periodontal | Not applicable | Recruiting | University of L'Aquila | 56 | 2024-11-08 | 2025-05-06 |
| Modified Widman Flap vs Fibre Retention Osseous Resective Surgery Modified Widman Flap (MWF), Fiber Retention Osseous Resective Surgery (FibReORS) - Periodontitis, Periodontal Pocket | Not applicable | Recruiting | University of Florence | 36 | 2024-10-21 | 2025-04-10 |
| Hyaluronic Acid and Polynucleotides for Supra-bony Defects Periodontal Access Flap (AF) + Combined Formulation of Hyaluronic acid and Polydeoxyribonucleotides (PNHA), Periodontal Access Flap (AF) - Periodontal Diseases, Wound Heal | Not applicable | Recruiting | Queen Mary University of London | 24 | 2024-10-21 | 2026-07-02 |
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Periodontitis (64) · Periodontal Diseases (49) · Periodontal Attachment Loss (24) · Alveolar Bone Loss (11) · Chronic Periodontitis (10) · Inflammation (5) · Gingival Diseases (4) · Gingival Hemorrhage (4) · Gingivitis (3) · Peri-Implantitis (3) · Aggressive Periodontitis (2) · Arthritis, Rheumatoid (2) · Diabetes Mellitus (2) · Acute Pain (1)
Stomatognathic Diseases (128) · Mouth Diseases (127) · Periodontal Diseases (79) · Periodontitis (64) · Periodontal Atrophy (31) · Pathological Conditions, Signs and Symptoms (21) · Pathologic Processes (20) · Musculoskeletal Diseases (14) · Bone Diseases (12) · Disease Attributes (12) · Bone Resorption (11) · Chronic Disease (10) · Metabolic Diseases (6) · Nutritional and Metabolic Diseases (6) · Gingival Diseases (5)
Tooth Exfoliation (11) · Root Planing (9) · proliferation regulatory factors, human urine (4) · Amelogenin (3) · Amoxicillin (3) · Hyaluronic Acid (3) · Metronidazole (3) · Photochemotherapy (3) · Chlorhexidine (2) · Hydrogen Peroxide (2) · Methylene Blue (2) · Anti-Bacterial Agents (1) · Azithromycin (1) · Cell- and Tissue-Based Therapy (1) · Clindamycin (1)
Brock University (8) · Cairo University (6) · Krishnadevaraya College of Dental Sciences & Hospital (6) · Ain Shams University (5) · Universidad de Murcia (4) · Federico II University (3) · University of Baghdad (3) · University of Florence (3) · Al-Azhar University (2) · British University In Egypt (2) · G. d'Annunzio University (2) · Mansoura University (2) · Marmara University (2) · Postgraduate Institute of Dental Sciences Rohtak (2) · Queen Mary University of London (2)
Italy (20) · Egypt (17) · Turkey (Türkiye) (14) · Canada (7) · Spain (7) · Iraq (6) · India (5) · United States (4) · Brazil (3) · China (3) · Germany (2) · Israel (2) · Norway (2) · United Kingdom (2) · Albania (1)
Wendy E Ward, PhD (5) · Hani El-Nahas, Professor (2) · Michele Paolantonio, DDS, MD (2) · Omnia Tawfik, Lecturer (2) · Wendy E Ward, Ph.D. (2) · Ahmed Fattouh, Bachelor (1) · Ahmed Y Gamal, PhD (1) · Ahmet Cemil Talmac, PhD (1) · Alaa A Rakha, master (1) · Amira Badran, PhD (1)
PMID 15944972, PMID 19680697, PMID 20618550, PMID 21718187, PMID 23003916, PMID 23880259, PMID 24565651, PMID 24945603, PMID 26423734, PMID 26895633, PMID 28635382, PMID 31190409, PMID 32383274, PMID 34376241, PMID 34791548, PMID 35141806, PMID 36715211, PMID 37672083, PMID 37740107, PMID 37986648, PMID 38395824, PMID 38676852, PMID 38884611, PMID 39011585, PMID 39235513, PMID 39402910, PMID 39627624, PMID 39686830, PMID 41568740, PMID 41664833, PMID 42021274, PMID 42474735
4UH3DE031129-02 (1)