1116 completed, 334 unknown, 155 recruiting, 117 not yet recruiting. 979 Not applicable, 156 Phase 2, 122 Phase 4, 94 Phase 3, 57 Phase 1.
Follow Periodontitis: new trials by email Literature Review of Periodontitis trials Research Report on Periodontitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy of Different Disinfection Technologies in Molar Non-Surgical Retreatment GentleWave System, Conventional rotary instrumentation with passive ultrasonic irrigation - Apical Periodontitis | Not applicable | Not yet recruiting | University of Alabama at Birmingham | 60 | 2027-07-01 | 2026-04-08 |
| Frankincense Versus Sodium Hypochlorite for Root Canal Disinfection Sodium hypochlorite 3%, Frankincense-based irrigant - Pulp Necrosis, Root Canal Infection | Early Phase 1 | Not yet recruiting | Oman Dental College | 30 | 2027-01-19 | 2026-09-22 |
| Alb-PRF as an Adjunct to Regenerative Periodontal Surgery Regenerative Periodontal Surgery With EDTA and Allogeneic Bone Graft, Albumin Platelet-Rich Fibrin - Periodontitis, Periodontitis Stage III | Not applicable | Not yet recruiting | Halil Ata BIÇAKÇIOĞLU | 24 | 2027-01-01 | 2026-09-04 |
| PRP-Assisted Regenerative Endodontics Versus Conventional Root Canal Treatment in Mature Necrotic Teeth PRP-Assisted Regenerative Endodontic Treatment, Conventional Root Canal Treatment - Pulp Necrosis, Apical Periodontitis | Not applicable | Not yet recruiting | TC Erciyes University | 10 | 2027-01-01 | 2026-11-05 |
| Alb-PRF as an Adjunct to Nonsurgical Periodontal Therapy Nonsurgical Periodontal Therapy, Albumin Platelet-Rich Fibrin - Periodontitis | Not applicable | Not yet recruiting | Halil Ata BIÇAKÇIOĞLU | 24 | 2026-12-01 | 2026-08-31 |
| Clinical Effectiveness of Oxygen-Releasing Oral Gel as an Adjunct to Scaling and Root Debridement in Patients With Severe Periodontal Pockets: A Randomized Clinical Trial Topical oxygen-releasing oral gel, No intervention - Periodontitis | Not applicable | Not yet recruiting | Universiti Sains Malaysia | 38 | 2026-11-01 | 2026-09-30 |
| Obesity and Oral Diseases in Adult Patients Lifestyle course., Bariatric surgery. - Obesity, Oral Diseases | Not yet recruiting | University of Bergen | 400 | 2026-11-01 | 2026-05-08 | |
| Laser-Activated Versus Passive Ultrasonic Irrigation in Endodontic Retreatment Photon-Induced Photoacoustic Streaming, Shock Wave Enhanced Emission Photoacoustic Streaming, Passive Ultrasonic Irrigation - Apical Periodontitis | Not applicable | Not yet recruiting | Inonu University | 90 | 2026-11-01 | 2026-10-29 |
| Post-operative Pain and Clinical Outcome After Single-cone Obturation With a Calcium Silicate-based Versus Epoxy Resin Sealer A calcium silicate-based sealer, An epoxy resin- based sealer - Post Operative Pain, Acute, Irreversible Pulpitis (Toothache) | Not applicable | Not yet recruiting | University Ghent | 138 | 2026-11-01 | 2026-11-06 |
| Spirulina Gel in the Treatment of Periodontitis spirulina gel exracted by 1.5% calcium chloride (CaCl2) aqueous solution., conventional scaling and root planing - Periodontitis, Periodontitis Stage II | Not applicable | Not yet recruiting | Misr University for Science and Technology | 20 | 2026-10-30 | 2026-10-27 |
| Evaluation of the Impact of Periodontitis and Its Treatment on Swallowing Functions and Oral Quality of Life Functionnal test - Periodontitis, Periodontal Diseases | Not applicable | Recruiting | University Hospital, Clermont-Ferrand | 44 | 2026-10-27 | 2026-11-02 |
| The Efficacy of Exosomes Combined With Synthetic Bone Graft for the Treatment of Periodontal Intra-bony Defects single flap approach, single flap approach combined with nanocrystalline hydroxyapatite bone substitute, Exosomes - Intra-Bony Defects in Periodontitis Patients | Early Phase 1 | Not yet recruiting | Khoshoe Al-mokhtar Mohammed | 30 | 2026-10-25 | 2026-10-27 |
| Salivary and GCF Biomarkers in Periodontal Health, Gingivitis and Periodontitis Clinical periodontal examination, ELISA-based biomarker analysis - Periodontal Health, Gingivitis | Not yet recruiting | Yuzuncu Yil University | 60 | 2026-10-15 | 2026-10-23 | |
| Evaluation of Masticatory Performance in Patients With Periodontitis Periodontitis, Adult, Periodontitis | Recruiting | University Hospital, Clermont-Ferrand | 100 | 2026-10-09 | 2026-10-16 | |
| Occlusal Force and Chewing After Periodontal Therapy Non-Surgical Periodontal Therapy - Periodontitis | Not applicable | Not yet recruiting | Mohammed Bin Rashid University of Medicine and Health Sciences | 30 | 2026-10-06 | 2026-08-19 |
| Apical Periodontitis and Glycemic Control in Diabetic and Non-diabetic Egyptian Sub-population Apical Periodontitis | Not yet recruiting | Cairo University | 88 | 2026-10-05 | 2026-10-02 | |
| Characterization of Small Intestinal Bacterial Overgrowth and Intestinal Barrier-Related Biomarkers in Patients With Severe Periodontitis Periodontitis (Stage 3), Periodontitis Stage IV | Recruiting | Iuliu Hatieganu University of Medicine and Pharmacy | 20 | 2026-10-02 | 2026-11-04 | |
| Retinal and Choroidal Changes in Periodontal Disease Periodontal Diseases, Periodontal Diseases Inflammation | Not yet recruiting | Zeliha Başak Çakır Erdil | 80 | 2026-10-01 | 2026-10-05 | |
| Diode Laser 635 nm and 810 nm Photodynamic Therapy as Adjuncts to Non-Surgical Periodontal Treatment 635 nm Diode Laser-Mediated aPDT + Non-Surgical Periodontal Treatment, 810 nm Diode Laser-Mediated aPDT + Non-Surgical Periodontal Treatment, Non-Surgical Periodontal Treatment Alone (Control) - Periodontitis | Not applicable | Not yet recruiting | Damascus University | 12 | 2026-10-01 | 2026-10-06 |
| Evaluation of Changes in Oral Health-related Quality of Life During the Treatment of Periodontitis. Periodontitis, Adult, Periodontitis | Not yet recruiting | University Hospital, Clermont-Ferrand | 100 | 2026-10-01 | 2026-10-09 |
Showing 20 of 1845. Sign in to see all of them.
Chronic Periodontitis (356) · Periodontal Diseases (328) · Periapical Periodontitis (242) · Gingivitis (132) · Periodontal Pocket (129) · Diabetes Mellitus (73) · Inflammation (60) · Aggressive Periodontitis (56) · Diabetes Mellitus, Type 2 (53) · Smoking (53) · Pain, Postoperative (50) · Dental Pulp Necrosis (41) · Alveolar Bone Loss (40) · Periodontal Attachment Loss (38)
Stomatognathic Diseases (1841) · Mouth Diseases (1839) · Periodontal Diseases (1517) · Pathological Conditions, Signs and Symptoms (603) · Pathologic Processes (547) · Disease Attributes (382) · Chronic Disease (374) · Jaw Diseases (260) · Periapical Diseases (248) · Infections (169) · Nutritional and Metabolic Diseases (162) · Metabolic Diseases (140) · Gingival Diseases (139) · Tooth Diseases (128)
Tooth Exfoliation (166) · Root Planing (162) · Metronidazole (32) · Chlorhexidine (28) · Amoxicillin (27) · Periodontal Index (22) · Photochemotherapy (21) · Probiotics (17) · Lasers, Semiconductor (16) · Calcium Hydroxide (15) · Control Groups (14) · Hyaluronic Acid (13) · proliferation regulatory factors, human urine (12) · Periodontal Debridement (11) · Saline Solution (11)
Postgraduate Institute of Dental Sciences Rohtak (66) · Cairo University (64) · Ain Shams University (35) · Government Dental College and Research Institute, Bangalore (25) · University of Sao Paulo (23) · Marmara University (20) · Saglik Bilimleri Universitesi (19) · Istanbul Medipol University Hospital (18) · Ondokuz Mayıs University (18) · University of Baghdad (18) · Ataturk University (17) · University of Siena (17) · Meenakshi Ammal Dental College and Hospital (16) · Abant Izzet Baysal University (14) · Al-Azhar University (14)
Turkey (Türkiye) (357) · Egypt (175) · India (137) · Italy (107) · United States (105) · Brazil (80) · Spain (50) · China (49) · France (42) · United Kingdom (31) · Germany (28) · Pakistan (26) · Iraq (25) · Chile (19) · Malaysia (16)
Gaetano Isola (8) · Beral Afacan (5) · Magda Feres, Professor (5) · Wendy E Ward, PhD (5) · Jaideep Mahendra, MDS,PhD (4) · Mauro P Santamaria, DDS, PhD (4) · Mauro P Santamaria, PhD (4) · Seyda Ersahan, Assoc.Prof. (4) · Ahmed Y Gamal, PhD (3) · Aliye Kamalak (3) · Dr. Rajinder Kumar Sharma, MDS (3) · Fernando O Costa, PhD (3)
PMID 33197289, PMID 32383274, PMID 29926952, PMID 29926951, PMID 3457698, PMID 21238793, PMID 26427036, PMID 28303587, PMID 34790237, PMID 36194420, PMID 1058834, PMID 14121956, PMID 14158464, PMID 14651280, PMID 14742657, PMID 15643744, PMID 16018754, PMID 16878680, PMID 17355365, PMID 18596969, PMID 19345793, PMID 19682173, PMID 21261673, PMID 22171999, PMID 22694350, PMID 23016867, PMID 23055587, PMID 24080100, PMID 24945603, PMID 25841875, PMID 26367496, PMID 26809431, PMID 28306142, PMID 29349511, PMID 29926495, PMID 31190409, PMID 31298974, PMID 33340075, PMID 33531183, PMID 37246231, PMID 37740107, PMID 38699834, PMID 39983975, PMID 40462486, PMID 41254181, PMID 5237684, PMID 9477818, PMID 9673164, PMID 10207836, PMID 10321215
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