108 completed, 31 unknown, 20 terminated, 13 withdrawn. 63 Not applicable, 49 Phase 2, 37 Phase 1, 27 Phase 3, 24 Phase 4.
Follow Photochemotherapy: new trials by email Literature Review of Photochemotherapy trials Research Report on Photochemotherapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase 2 Study of Methylene Blue Photodynamic Therapy for Treatment of Breast Abscesses Standard of care breast abscess drainage, Methylene Blue, Lipid Emulsion - Breast Abscess | Phase 2 | Not yet recruiting | University of Rochester | 50 | 2027-07-01 | 2026-08-19 |
| Advancing Antimicrobial Photodynamic Therapy to Prevent Infection in Osseointegrated Prosthesis Patients 5-aminolevulinic acid (5-ALA), Photodynamic therapy (PDT) - Amputation, Osseointegration | Not yet recruiting | Dartmouth-Hitchcock Medical Center | 10 | 2026-10-01 | 2026-07-29 | |
| Photoimmunotherapy With ASP-1929 and Cemiplimab for the Treatment of Refractory, Inoperable, and Metastatic Stage IIIB-IV Non-small Cell Lung Cancer Biospecimen Collection, Cemiplimab, Cetuximab Sarotalocan Sodium - Lung Non-Small Cell Carcinoma, Metastatic Lung Non-Small Cell Carcinoma | Phase 2 | Withdrawn | Roswell Park Cancer Institute | 2026-08-15 | 2026-09-15 | |
| An Open-Label Pharmacokinetic Study for Patients With Actinic Keratosis on the Upper Extremities or the Face Investigational drug, Photodynamic therapy - Actinic Keratosis (AK) | Phase 1 | Recruiting | Sun Pharmaceutical Industries Limited | 48 | 2026-08-04 | 2026-08-13 |
| PDT vs Peels for Treatment of Actinic Keratoses Photodynamic Therapy, Chemical Peels - Actinic Keratoses | Phase 2 | Not yet recruiting | Northwestern University | 60 | 2026-08-01 | 2026-07-01 |
| Effects of Periodontal Treatment Associated With Antimicrobial Photodynamic Therapy on Halitosis in Patients With Diabetes Mellitus Scaling and root planing, Photodynamic Therapy with Conventional Methylene Blue - Type 2 Diabetes, Halitosis | Not applicable | Recruiting | University of Sao Paulo | 32 | 2026-04-02 | 2026-03-16 |
| Vitamin D Effects on Immune Microenvironment of Nonmelanoma Skin Cancer After Photodynamic Therapy (PDT) Vitamin D (VitD), Placebo, Photodynamic therapy (PDT) - Nonmelanoma Skin Cancer, Basal Cell Carcinoma | Not applicable | Recruiting | Case Comprehensive Cancer Center | 54 | 2026-02-25 | 2026-08-18 |
| Antimicrobial Photodynamic Therapy Or Lingual Scraper Associated With Periodontal Treatment In The Reduction Of Halitosis. Tongue scraper and oral rinse treatment, Tongue scraper and aPDT (photodynamic therapy), full mouth scaling - Halitosis, Halitoses | Not applicable | Completed | Medical University of Silesia | 48 | 2025-06-20 | 2026-03-05 |
| Photodynamic Therapy for Glioblastoma Multiforme Based on Metaverse and Yellow Fluorescence Photodynamic therapy (PDT), GBM patients recevied traditional treatment options - Glioblastoma Multiforme (GBM) | Not yet recruiting | Zhejiang Provincial People's Hospital | 100 | 2025-06-01 | 2025-04-22 | |
| Toluidine Blue-Based Photodynamic Therapy for Antibacterial Activity and Postoperative Pain Toluidine Blue O (0.1 mg/mL), 630-nm LED Light Device, Photodynamic Therapy (PDT) - Root Canal Infection | Not applicable | Active not recruiting | Ataturk University | 50 | 2025-06-01 | 2025-12-05 |
| Antimicrobial Efficacy of NaOCl and PDT in Primary Root Canal Treatment Sodium Hypochlorite Irrigation, Sodium Hypochlorite Irrigation Plus Photodynamic Therapy, Photodynamic Therapy Adjunct Evaluation - Dental Pulp Necrosis, Apical Periodontitis | Not applicable | Completed | Bayan Alqrenawi | 64 | 2025-05-19 | 2026-07-01 |
| Light Therapy Intervention in Individuals With Parkinson's Disease Red Light (PDT), Placebo - Parkinson Disease | Not applicable | Recruiting | University of Delaware | 20 | 2025-04-04 | 2025-04-08 |
| Clinical Comparative Evaluation of the Use of Photodynamic Therapy in Conjunction With the Use of Vitamin D in Management Stage II Grade B Periodontitis Patients non-surgical periodontal therapy (SRP) and Photodynamic therapy (PDT) with systemic vitamin D - Vitamin D Deficiency | Not applicable | Completed | Cairo University | 24 | 2025-03-01 | 2026-05-26 |
| Red Light Childhood Myopia Proof-of-concept Red Light (PDT) - Myopia | Not applicable | Not yet recruiting | University College, London | 24 | 2025-02-01 | 2025-01-13 |
| Exploring Different Dose-frequency Home Photodynamic Therapy Protocols Using a Novel Home-targeted LED Device for Onychomycosis Photodynamic Therapy with Conventional Methylene Blue, urea 40% cream - Onychomycosis of Toenails, Onychomycosis of Fingernail | Not applicable | Active not recruiting | Chulalongkorn University | 50 | 2025-01-13 | 2026-05-12 |
| Photodynamic Therapy of Primary Localized Prostate Cancer With the SpectraCure P18 System Photodynamic Therapy (PDT), Verteporfin Injection - Prostate Cancer | Phase 1 / Phase 2 | Recruiting | SpectraCure AB | 43 | 2025-01-06 | 2026-05-01 |
| Photodynamic Therapy and Post-Endodontic Pain in Undergraduate-Performed Treatments Photodynamic Therapy - Pulpitis | Completed | Atlas University | 95 | 2025-01-01 | 2025-11-28 | |
| Diode Laser as an Adjunct to Professional Mechanical Plaque Removal Professional mechanical plaque removal and Laser, Professional mechanical plaque removal - Periodontitis, Pocket, Periodontal | Not applicable | Active not recruiting | University of Sulaimani | 40 | 2025-01-01 | 2026-05-04 |
| Clinical and Metabolomics Studies on the Improvement of Ovarian Reserve by Acupoint Photodynamic Therapy and Traditional Chinese Medicine Treatment Traditional Chinese Medicine, Photodynamic therapy (PDT), Placebo - Diminished Ovarian Reserve (DOR) | Phase 3 | Recruiting | Peking Union Medical College Hospital | 90 | 2024-12-20 | 2026-01-29 |
| Photoradiation With Verteporfin to Facilitate Immunologic Activity of Pembrolizumab in Unresectable, Locally Advanced or Metastatic Pancreatic Cancer Biopsy, Biospecimen Collection, Computed Tomography - Locally Advanced Pancreatic Adenocarcinoma, Metastatic Pancreatic Adenocarcinoma | Phase 2 | Active not recruiting | Mayo Clinic | 24 | 2024-12-06 | 2026-06-18 |
Showing 20 of 197. Sign in to see all of them.
Keratosis, Actinic (23) · Macular Degeneration (14) · Chronic Periodontitis (11) · Periodontitis (9) · Carcinoma, Basal Cell (8) · Cholangiocarcinoma (8) · Carcinoma, Non-Small-Cell Lung (7) · Halitosis (6) · Squamous Cell Carcinoma of Head and Neck (6) · Acne Vulgaris (5) · Choroidal Neovascularization (5) · Bile Duct Neoplasms (4) · Skin Neoplasms (4) · Colorectal Neoplasms (3) · Diabetes Mellitus, Type 2 (3)
Roswell Park Cancer Institute (12) · University of Sao Paulo (8) · University of Nove de Julho (7) · Mayo Clinic (6) · Bispebjerg Hospital (4) · Cairo University (4) · Case Comprehensive Cancer Center (4) · Galderma R&D (3) · Light Sciences LLC (3) · National Cancer Institute (NCI) (3) · Northwestern University (3) · Shahid Beheshti University of Medical Sciences (3) · Sun Yat-sen University (3) · University of Zurich (3) · Weill Medical College of Cornell University (3)
United States (70) · Brazil (17) · China (17) · Germany (9) · Canada (6) · Denmark (6) · Switzerland (6) · Poland (5) · France (4) · Egypt (3) · Saudi Arabia (3) · South Korea (3) · Taiwan (3) · Turkey (Türkiye) (3) · Austria (2)
Hassan Arshad (3) · Murad Alam, MD (3) · Edward Maytin, MD, PhD (2) · Edward V. Maytin, MD, PhD (2) · Michel Kahaleh, MD (2) · Stuart Marcus, MD, PhD (2) · Zohreh Tehranchi-nia, assist.prof. (2) · Aaron Mangold (1) · Albrecht Hoffmeister, Prof.Dr.med. (1) · Alexander Kharlamov, M.D., Ph.D. (1) · Alexandra Geusau, Prof. Dr. (1) · Allen Ho, MD (1) · Amr Ahmed (1) · Andrew Strong, Ph.D (1)
PMID 14689344, PMID 16310147, PMID 19878113, PMID 20510306, PMID 23055220, PMID 23703448, PMID 23815349, PMID 23868427, PMID 24485665, PMID 25555191, PMID 25808980, PMID 27084279, PMID 27330702, PMID 27594672, PMID 28114928, PMID 28498507, PMID 28793884, PMID 29926495, PMID 30133749, PMID 30222972, PMID 30392080, PMID 30985667, PMID 31027098, PMID 31277154, PMID 31859395, PMID 31955461, PMID 32383274, PMID 32727733, PMID 33647286, PMID 33987732, PMID 34087466, PMID 34261044, PMID 35314199, PMID 35367616, PMID 36396084, PMID 36727801, PMID 39666443, PMID 39838651, PMID 40522203, PMID 40846240, PMID 41039790, PMID 41091662, PMID 41375569, PMID 42625164
P01CA084203 (3), P30CA016056 (3), 2015 (1), 2018 (1), 5UH3CA189901-04 (1), P01CA055791 (1), P30CA060553 (1), R01CA111603 (1), R21CA153594 (1), R44CA250727 (1), U01CA099168 (1), UL1TR001412 (1)