107 completed, 38 unknown, 18 terminated, 13 recruiting. 122 Not applicable, 17 Phase 4, 11 Phase 2, 10 Phase 3, 2 Phase 1.
Follow Paroxysmal Atrial Fibrillation: new trials by email Literature Review of Paroxysmal Atrial Fibrillation trials Research Report on Paroxysmal Atrial Fibrillation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Catheter Ablation Using a Novel Navigation and Imaging System VERAFEYE System - Paroxysmal Atrial Fibrillation | Not yet recruiting | LUMA Vision Ltd. | 100 | 2027-01-01 | 2026-09-15 | |
| Evaluation of the Safety and Effectiveness of the Globe® Pulsed Field System for Treating Patients With Symptomatic Paroxysmal Atrial Fibrillation Globe Pulsed Field System - Paroxysmal Atrial Fibrillation | Not applicable | Not yet recruiting | Kardium Inc. | 250 | 2026-12-01 | 2026-07-20 |
| A Multicenter Feasibility Study With the VERAFEYE Imaging and Guidance System as Anatomical Navigation System Catheter Ablation - Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation | Not applicable | Not yet recruiting | LUMA Vision Ltd. | 50 | 2026-11-01 | 2026-09-17 |
| Pulsed Field Ablation for Paroxysmal Atrial Fibrillation: Clinical Efficacy and Left Atrial Function Protection Novel Pulsed Field Ablation System, Radiofrequency Ablation Catheter - Paroxysmal Atrial Fibrillation, Pulsed Field Ablation | Not applicable | Not yet recruiting | Tianjin Medical University General Hospital | 220 | 2026-10-01 | 2026-10-14 |
| Conscious Sedation Versus General Anesthesia for Pulsed Field Ablation in Paroxysmal Atrial Fibrillation Local Anesthesia With Conscious Sedation, General Anesthesia, VARIPULSE Pulsed Field Ablation System - Paroxysmal Atrial Fibrillation | Not applicable | Recruiting | China National Center for Cardiovascular Diseases | 390 | 2026-06-01 | 2026-10-26 |
| REPRESENT-PF Registry FARAWAVE Pulsed Field Ablation Catheter - Persistent Atrial Fibrillation, Paroxysmal Atrial Fibrillation | Recruiting | Vivek Reddy | 275 | 2026-03-30 | 2026-04-17 | |
| Evaluation of Novel Waveforms Delivered Using the FARAPULSE™ PFA System FARAPULSE™ Pulsed Field Ablation (PFA) System - Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation | Not applicable | Recruiting | Boston Scientific Corporation | 200 | 2026-02-12 | 2026-10-23 |
| Determinates of Atrial Tracking and Prevalence of Atrial Fibrillation in the Micra AV2 (DANCE AFIB) Micra AV2- Observational - Paroxysmal Atrial Fibrillation | Recruiting | Northwell Health | 50 | 2025-12-29 | 2026-02-04 | |
| Pulsed Field Ablation of SVC and PV in Paroxysmal Atrial Fibrillation (PASPA Study) PFA - PV + SVCI, PFA - PVI only - Paroxysmal Atrial Fibrillation, Paroxysmal Atrial Fibrillation (PAF) | Not applicable | Not yet recruiting | Changhai Hospital | 650 | 2025-11-01 | 2025-09-25 |
| Burst Stimulation for Paroxysmal Atrial Fibrillation Pulmonary Vein Isolation (PVI) + Superior Vena Cava Isolation (SVCI), Burst Stimulation - Paroxysmal Atrial Fibrillation | Not applicable | Recruiting | Zhibing Lu | 240 | 2025-10-13 | 2025-12-15 |
| Safety and Efficacy of Very High-Power Short-Duration Radiofrequency Ablation With Half-Normal Saline Irrigation for Pulmonary Vein Isolation vHPSD Ablation with Half-Normal Saline, vHPSD Ablation with Normal Saline - Paroxysmal Atrial Fibrillation | Not applicable | Enrolling by invitation | First Affiliated Hospital of Ningbo University | 86 | 2025-10-06 | 2026-10-02 |
| A Study Assessing Arrhythmia Mapping With a Multi-Electrode Mapping Catheter Paddle-Shaped, High-Density, Multi-Electrode Mapping Catheter - Scar-related Atrial Tachycardia, Persistent Atrial Fibrillation | Not applicable | Recruiting | Biosense Webster, Inc. | 90 | 2025-09-15 | 2026-09-28 |
| Pragmatic Evaluation of a Pentaspline Pulsed Field Ablation System to Treat Atrial Fibrillation and Related Arrhythmias Farapulse Catheter System, Low-dose Colchicine - Persistent Atrial Fibrillation, Paroxysmal Atrial Fibrillation | Phase 4 | Active not recruiting | Vivek Reddy | 275 | 2025-04-15 | 2026-04-14 |
| EXercise Cardiac Magnetic Resonance Assessment of Left Atrial Mechanics Following Ablation Self- Report Evaluation-Duke Activity Status Index, Self- Report Evaluation Atrial Fibrillation Effect on Quality of Life Questionnaire, Cardiopulmonary exercise test (CPET) - Paroxysmal Atrial Fibrillation | Recruiting | Virginia Commonwealth University | 50 | 2024-12-26 | 2026-03-12 | |
| ADVENT Trial Long Term Outcomes Evaluating Atrial Fibrillation Progression Study Paroxysmal Atrial Fibrillation | Completed | Boston Scientific Corporation | 364 | 2024-10-31 | 2026-03-02 | |
| ADVENT Post Approval Study FARAPULSE™ Pulsed Field Ablation System - Paroxysmal Atrial Fibrillation | Active not recruiting | Boston Scientific Corporation | 228 | 2024-09-25 | 2026-10-23 | |
| FIH of PFBalloon for PVI PVI with a novel PFA catheter - Paroxysmal Atrial Fibrillation | Not applicable | Active not recruiting | The Third People's Hospital of Chengdu | 35 | 2024-07-10 | 2026-01-06 |
| POLARx Post Approval Study (POLARx PAS) Boston Scientific Cardiac Cryoablation System - Paroxysmal Atrial Fibrillation | Not applicable | Completed | Boston Scientific Corporation | 200 | 2024-06-28 | 2026-07-27 |
| The Impact of Expandable Cryoballoon on Autonomic Control of the Heart cryoablation of atrial fibrillation using only 28 mm size balloon, cryoablation of atrial fibrillation using expandable balloon (28 / 31 mm) - Paroxysmal Atrial Fibrillation | Not applicable | Active not recruiting | Wroclaw Medical University | 100 | 2024-05-10 | 2026-08-10 |
| Accelerated Pacing in Patients Undergoing Pace-and-ablate Strategy With LBBAP: a Randomized Controlled Pilot Trial Accelerated pacing, Current standard of care - Atrial Fibrillation, Permanent Atrial Fibrillation | Not applicable | Unknown | Maastricht University Medical Center | 50 | 2024-05-01 | 2024-04-22 |
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Atrial Fibrillation (201) · Arrhythmias, Cardiac (11) · Atrial Flutter (4) · Tachycardia, Ventricular (4) · Ventricular Premature Complexes (4) · Cardiovascular Diseases (3) · Heart Diseases (3) · Ischemic Stroke (3) · Stroke (3) · Hypertension (2) · Recurrence (2) · Sick Sinus Syndrome (2) · Anxiety Disorders (1) · Atrial Premature Complexes (1) · Cardiomyopathies (1)
Pathologic Processes (201) · Pathological Conditions, Signs and Symptoms (201) · Cardiovascular Diseases (198) · Heart Diseases (198) · Arrhythmias, Cardiac (190) · Vascular Diseases (8) · Cardiac Conduction System Disease (7) · Nervous System Diseases (6) · Brain Diseases (5) · Cardiac Complexes, Premature (5) · Central Nervous System Diseases (5) · Cerebrovascular Disorders (5) · Tachycardia (4) · Arrhythmia, Sinus (2) · Disease Attributes (2)
Catheter Ablation (12) · Radiofrequency Ablation (9) · Flecainide (5) · Propafenone (4) · Anti-Arrhythmia Agents (3) · Saline Solution (3) · Sotalol (3) · Amiodarone (2) · Botulinum Toxins (2) · Therapeutics (2) · Albuterol (1) · Anesthesia, General (1) · Anesthesia, Local (1) · Antazoline (1) · Atropine (1)
Boston Scientific Corporation (20) · Abbott Medical Devices (16) · Biosense Webster, Inc. (15) · Meshalkin Research Institute of Pathology of Circulation (6) · Medtronic Cardiac Ablation Solutions (5) · CardioFocus (4) · Vivek Reddy (4) · Yonsei University (4) · Medtronic Cardiac Rhythm and Heart Failure (3) · Universitätsklinikum Hamburg-Eppendorf (3) · VytronUS, Inc. (3) · AZ Sint-Jan AV (2) · C. R. Bard (2) · Danderyd Hospital (2) · Deutsches Herzzentrum Muenchen (2)
United States (57) · Germany (38) · Czechia (27) · France (22) · United Kingdom (22) · Canada (20) · China (20) · Italy (20) · Netherlands (20) · Belgium (19) · Spain (15) · South Korea (11) · Austria (10) · Russia (9) · Switzerland (9)
Vivek Reddy, MD (9) · Petr Neuzil, MD, PhD (4) · Andrea Natale, MD (3) · Evgeny Pokushalov, MD, PhD (3) · Kristin Ruffner, PhD (3) · Pierre Jais, MD (3) · Arash Aryana, MD, PhD (2) · Armin Luik, MD (2) · Biosense Webster, Inc. Clinical Trial (2) · Florian Hintringer, MD (2) · Ignacio Garcia Bolao, MD (2) · Khaldoun Tarakji, MD (2) · Kristin Ruffner (2) · Oussama Wazni (2) · Prapa Kanagaratnam, PhD (2)
PMID 31085321, PMID 17627105, PMID 18191740, PMID 19029470, PMID 19356538, PMID 20048214, PMID 20445461, PMID 20876603, PMID 20889311, PMID 21385887, PMID 21424845, PMID 22217936, PMID 23210695, PMID 23423966, PMID 23500312, PMID 23644091, PMID 23748210, PMID 24016147, PMID 24097372, PMID 24128369, PMID 24433324, PMID 24656107, PMID 24685669, PMID 25634002, PMID 25644659, PMID 26211828, PMID 26260733, PMID 26297786, PMID 26310300, PMID 26383722, PMID 26486855, PMID 27516462, PMID 28339554, PMID 28750697, PMID 28982836, PMID 29092038, PMID 30414841, PMID 30638392, PMID 31320006, PMID 31630538, PMID 31693319, PMID 31978593, PMID 32078362, PMID 32371199, PMID 32614422, PMID 32819528, PMID 32819529, PMID 32879974, PMID 33150753, PMID 33450010
K23HL166956 (1)