Cardiac Conduction System Disease: Clinical Trials

559 completed, 202 unknown, 170 recruiting, 96 terminated. 517 Not applicable, 97 Phase 4, 53 Phase 3, 52 Phase 2, 36 Phase 1.

By phase and status

Phase	Trials	Status
Not applicable	517	Completed 237, Recruiting 82, Unknown 79, Terminated 43, Not yet recruiting 32, Active not recruiting 23, Withdrawn 16, Enrolling by invitation 4, Suspended 1
Phase 4	97	Completed 59, Unknown 22, Terminated 6, Recruiting 4, Active not recruiting 2, Not yet recruiting 2, Withdrawn 2
Phase 3	53	Completed 25, Terminated 13, Recruiting 6, Withdrawn 4, Unknown 3, Active not recruiting 1, Not yet recruiting 1
Phase 2	52	Completed 23, Terminated 8, Recruiting 7, Unknown 6, Not yet recruiting 3, Withdrawn 3, Active not recruiting 1, Enrolling by invitation 1
Phase 1	36	Completed 21, Unknown 5, Terminated 4, Recruiting 3, Withdrawn 2, Active not recruiting 1
Early Phase 1	6	Terminated 3, Active not recruiting 1, Recruiting 1, Withdrawn 1

Follow Cardiac Conduction System Disease: new trials by email Literature Review of Cardiac Conduction System Disease trials Research Report on Cardiac Conduction System Disease

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Leadless Versus Conventional Pacemakers: Effects on Heart Function and Heart Failure Leadless pacemaker implantation, Conventional transvenous pacemaker implantation - Bradycardia, Atrioventricular Block	Not applicable	Not yet recruiting	Karl Landsteiner University of Health Sciences	760	2027-11-01	2026-11-10
VT Cryoablation System Post-Market Clinical Follow-up (PMCF) Study VT Cryoablation System - Ventricular Tachycardia	Not applicable	Not yet recruiting	Adagio Medical	130	2027-01-01	2026-10-13
Stellate Ganglion Neuromodulation for the Treatment of Electrical Storm Stellate Ganglion Block Injection with Bupivicaine, Sham procedure control - Ventricular Tachycardia (V-Tach) Storm	Not applicable	Not yet recruiting	Population Health Research Institute	300	2027-01-01	2026-10-08
Dual Energy Focal Ablation of Premature Ventricular Complexes Dual Energy THERMOCOOL SMARTTOUCH™ SF (STSF) Bi-Directional Navigation catheter with TRUPULSE™ Generator - Premature Ventricular Contractions	Not applicable	Not yet recruiting	Konstantinos Siontis	60	2027-01-01	2026-11-13
Predicting Severe Cardiac Arrhythmias in the Perioperative Period Using AI-ECG digital single-channel ECG recording - Atrial Fibrillation, Atrioventricular Block, Second and Third Degree		Not yet recruiting	I.M. Sechenov First Moscow State Medical University	300	2026-12-31	2026-02-10
Premature Ventricular Complex and Diet Inflamatuar Index Premature Ventricular Complexes, Diet Quality		Not yet recruiting	Izmir Democracy University	100	2026-11-15	2026-10-13
Belgo-Luxembourg Leadless PM Registry CT scan heart, 24 hour ambulatory ECG monitoring - Bradyarrhythmias, AV Block Complete	Not applicable	Not yet recruiting	Universitaire Ziekenhuizen KU Leuven	190	2026-11-01	2026-10-19
Physical Activity and Functional Capacity in Patients With Congenital Long QT Syndrome Questionnaires, Cardiopulmonary exercise testing, 24-hour Holter monitoring - Long QT Syndrome, Channelopathies		Not yet recruiting	University of Sao Paulo	120	2026-11-01	2026-10-07
MAGiC - Congenital Heart DIsease Cardiac ablation using the MAGiC Ablation Catheter - Supraventricular Tachycardia (SVT), Congenital Heart Disease (CHD)		Not yet recruiting	Stereotaxis	40	2026-10-31	2026-09-10
LBBAP Versus ILR in Patients With New-Onset LBBB and Moderately Reduced LVEF After TAVI Left bundle branch area pacing with pacemaker, Implantation loop recorder - TAVI(Transcatheter Aortic Valve Implantation), Left Bundle Branch Block	Not applicable	Not yet recruiting	University Hospital, Clermont-Ferrand	700	2026-10-15	2026-11-02
Transjugular Approach for Implantation of Active Fixation Leadless Pacemakers Aveir VR Leadless Pacemaker - Bradycardia, Heart Block	Not applicable	Recruiting	Min Shen	15	2026-10-10	2026-11-10
Procedural Endpoint in Left Bundle Branch Area Pacing: Conduction System Capture Versus LV Septal Capture LBBAP with mandatory left ventricular conduction system capture (LBBP or LFP), LBBAP with left ventricular septal capture as the accepted procedural endpoint (LVSP) - Bradycardia, Atrioventricular Block	Not applicable	Not yet recruiting	Yonsei University	300	2026-10-01	2026-09-04
Percutaneous Stellate Ganglion Block as First Line Treatment in Patients With Electrical Storm: the STAR 2 Study L-PSGB first - Electrical Storm, VT	Phase 3	Not yet recruiting	Fondazione IRCCS Policlinico San Matteo di Pavia	180	2026-10-01	2026-09-29
MRI-guided Ventricular Tachycardia Ablation in Patients With Structural Heart Disease LGE-MRI-integrated EAM-guided catheter ablation, Conventional EAM-guided catheter ablation - Ventricular Tachycardia (VT), Ischemic Cardiomyopathy	Not applicable	Not yet recruiting	China National Center for Cardiovascular Diseases	526	2026-10-01	2026-10-27
Head-to-Head (H2H) Comparison of Ambulatory Cardiac ECG Monitors in Japan Application of ambulatory cardiac monitor - Atrial Fibrillation (AF), Atrial Flutter	Not applicable	Not yet recruiting	iRhythm Technologies, Inc.	130	2026-09-30	2026-10-19
Evaluation of the DuoVT PFA System for Ventricular Tachycardia Ablation procedure with DuoVT PFA system - Ventricular Tachycardia	Not applicable	Recruiting	Abbott Medical Devices	50	2026-09-29	2026-10-16
ATR 1072 in Participants With PRKAG2 Syndrome ATR 1072 - Cardiac Glycogenosis, Cardiomyopathy	Phase 1 / Phase 2	Recruiting	Atrium Therapeutics	37	2026-09-14	2026-09-18
Cardiac Arrhythmias in Pediatric Emergency Department Arrhythmias, Cardiac, Tachycardia, Supraventricular		Not yet recruiting	Assiut University	73	2026-09-13	2026-09-17
OPTImizing Lead Placement in Patients Requiring Pacemaker After Cardiac Surgery Left bundle branch area pacing, Conventional pacing strategy - Atrioventricular Block, Cardiac Surgery	Not applicable	Not yet recruiting	Sahlgrenska University Hospital	110	2026-09-10	2026-08-31
Cor360: Clinician-Facing Broad-Spectrum Cardiac Phenotyping and Risk Assessment Using COR® Wearable ECG to Inform Outcomes-Oriented Care Pathways COR Wearable ECG Monitoring, Cor360 Clinician-Facing Decision-Aid Reporting - Cardiovascular Diseases, Cardiovascular Diseases Risk		Enrolling by invitation	Peerbridge Health, Inc	1000	2026-08-20	2026-08-21

Showing 20 of 1178. Sign in to see all of them.

Narrower conditions

Tachycardia, Ventricular (440)  ·  Tachycardia (173)  ·  Arrhythmias, Cardiac (160)  ·  Atrial Fibrillation (150)  ·  Heart Failure (137)  ·  Ventricular Fibrillation (124)  ·  Atrioventricular Block (113)  ·  Ventricular Premature Complexes (103)  ·  Long QT Syndrome (101)  ·  Bradycardia (99)  ·  Bundle-Branch Block (93)  ·  Sick Sinus Syndrome (93)  ·  Death, Sudden, Cardiac (78)  ·  Tachycardia, Supraventricular (71)  ·  Brugada Syndrome (51)

Broader conditions

Cardiovascular Diseases (1147)  ·  Pathological Conditions, Signs and Symptoms (1141)  ·  Heart Diseases (1140)  ·  Pathologic Processes (1134)  ·  Arrhythmias, Cardiac (1016)  ·  Tachycardia (520)  ·  Heart Block (254)  ·  Congenital, Hereditary, and Neonatal Diseases and Abnormalities (187)  ·  Congenital Abnormalities (140)  ·  Cardiovascular Abnormalities (139)  ·  Heart Defects, Congenital (131)  ·  Cardiac Complexes, Premature (116)  ·  Vascular Diseases (93)  ·  Arrhythmia, Sinus (92)

Interventions

Catheter Ablation (38)  ·  Defibrillators, Implantable (23)  ·  Amiodarone (18)  ·  Cardiac Resynchronization Therapy (16)  ·  Sotalol (13)  ·  Exercise Test (12)  ·  Electrocardiography (11)  ·  Radiosurgery (11)  ·  Radiofrequency Ablation (10)  ·  Saline Solution (10)  ·  Adenosine (9)  ·  Flecainide (9)  ·  Anti-Arrhythmia Agents (8)  ·  Blood Specimen Collection (7)  ·  Echocardiography (7)

Sponsors

Medtronic Cardiac Rhythm and Heart Failure (45)  ·  Abbott Medical Devices (43)  ·  Boston Scientific Corporation (34)  ·  Biotronik SE & Co. KG (33)  ·  Vanderbilt University Medical Center (13)  ·  Maastricht University Medical Center (10)  ·  Assiut University (9)  ·  Imperial College London (8)  ·  Mayo Clinic (8)  ·  Nantes University Hospital (8)  ·  Universitair Ziekenhuis Brussel (8)  ·  Biosense Webster, Inc. (7)  ·  Medtronic (7)  ·  Milestone Pharmaceuticals Inc. (7)  ·  University of British Columbia (7)

Countries

United States (367)  ·  Germany (123)  ·  France (112)  ·  Italy (107)  ·  Canada (100)  ·  United Kingdom (90)  ·  China (81)  ·  Spain (80)  ·  Netherlands (74)  ·  Belgium (62)  ·  Denmark (54)  ·  Czechia (50)  ·  Switzerland (45)  ·  Austria (44)  ·  Australia (37)

Top investigators

Vivek Reddy, MD (9)  ·  Nicole Harbert (5)  ·  Yan Wang, PhD (5)  ·  Gerhard Hindricks, Prof. Dr. (4)  ·  Satish R Raj, MD MSCI (4)  ·  Antonio Berruezo, MD, PhD (3)  ·  Carlo Pappone, MD (3)  ·  Dhanunjaya Lakkireddy, MD (3)  ·  Eline Vandael, PhD-student (3)  ·  Grant Kim (3)  ·  James E Tisdale, PharmD (3)  ·  Kevin Vernooy, MD, PhD (3)  ·  Koonlawee Nademanee, MD (3)  ·  Martin C Burke, DO (3)

Results publications

PMID 31698933, PMID 21712276, PMID 15670960, PMID 20231152, PMID 20463331, PMID 21098435, PMID 21403098, PMID 24293174, PMID 25908064, PMID 26314489, PMID 26988379, PMID 27149033, PMID 27402231, PMID 29025197, PMID 29173611, PMID 29545359, PMID 29650119, PMID 30354289, PMID 30462207, PMID 31330187, PMID 31647530, PMID 33999698, PMID 34167929, PMID 34307499, PMID 34387126, PMID 35776711, PMID 36700426, PMID 37671601, PMID 10492412, PMID 10676584, PMID 10677747, PMID 10707756, PMID 10716483, PMID 10793602, PMID 10805823, PMID 10902039, PMID 11136691, PMID 11175486, PMID 11310300, PMID 11513442, PMID 12063369, PMID 12494610, PMID 12717123, PMID 12842643, PMID 1309182, PMID 1356374, PMID 14563591, PMID 14585254, PMID 14625108, PMID 14662714

NIH funding

2014 (4), 2016 (2), 2018 (2), 2025 (2), 2005 (1), 2009 (1), 2017 (1), 2019 (1), 2023 (1), 5UL1TR000445-07 (1), K23RR020783 (1), OT2OD028201 (1), P01HL056693 (1), R01HL033843 (1), R01HL034071 (1)