6012 completed, 2519 unknown, 1966 recruiting, 779 not yet recruiting. 6116 Not applicable, 1159 Phase 2, 895 Phase 3, 540 Phase 1, 538 Phase 4.
Follow Cerebrovascular Disorders: new trials by email Literature Review of Cerebrovascular Disorders trials Research Report on Cerebrovascular Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effect of Sympathetic Modulation on Cerebral Vasospasm Secondary to Aneurysmal Subarachnoid Hemorrhage Vectris trial leads and stimulation, Sham - Vasospasm, Cerebral, Aneurysmal Subarachnoid Hemorrhage | Not applicable | Suspended | University of Alabama at Birmingham | 25 | 2028-07-31 | 2026-09-24 |
| Essential Acute Stroke Care in Low Resource Settings: a Pilot studY Acute stroke care Intervention arm - Acute Stroke | Not applicable | Not yet recruiting | The George Institute | 300 | 2027-12-30 | 2026-06-11 |
| REstoring Flow by REvascularization With Submaximal Angioplasty in Hemodynamic IntraCranial Atherosclerotic Stenosis Submaximal balloon angioplasty - Intracranial Atherosclerotic Disease, Stroke | Not applicable | Not yet recruiting | Case Western Reserve University | 159 | 2027-10-01 | 2025-11-04 |
| COOLing of the Ischemic PENumbra in Patients With Acute Ischemic Stroke. PEN-Cool Conductive Head-and-Neck Cooling System, Standard Reperfusion Therapy / Routine Care - Acute Ischemic Stroke | Not applicable | Not yet recruiting | Christian Medical College and Hospital, Ludhiana, India | 55 | 2027-09-01 | 2026-09-28 |
| Glial Fibrillary Acidic Protein Testing and Handheld Near Infrared Spectroscopy Technology CEREBO in India. GFAP/D-Dimer Point-of-Care Testing & CEREBO Near-Infrared Spectroscopy (NIRS), CT Head - Stroke | Not applicable | Not yet recruiting | Christian Medical College and Hospital, Ludhiana, India | 232 | 2027-09-01 | 2026-09-28 |
| Stroke Rehabilitation Using Extended Reality. RehAtt XR System - Stroke | Not applicable | Not yet recruiting | Värmland County Council, Sweden | 9 | 2027-09-01 | 2026-09-10 |
| Neuro-Intermuscular Coordination Enhancement (NICE) Rehabilitation Through Human-Machine Interaction in Chronic Stroke Neuromuscular coordination enhancement (NICE) intervention, EMG Amplitude Biofeedback Exercise - Chronic Stroke-related Upper-extremity Motor Impairment, Motor Module-guided Rehabilitation Targeting Impaired Intermuscular Coordination and Motor Recovery | Early Phase 1 | Not yet recruiting | University of Houston | 48 | 2027-08-01 | 2026-06-18 |
| The Feasibility and Acceptability of a Gait Training Program Based on Telerehabilitation After Stroke STEP-Tech intervention - Stroke | Not applicable | Not yet recruiting | University of Exeter | 12 | 2027-08-01 | 2026-06-03 |
| Alirocumab for Stabilisation of Symptomatic Vulnerable Carotid Plaque Alirocumab, Placebo, Atorvastatin - Carotid Stenosis | Phase 3 | Not yet recruiting | Middle East North Africa Stroke and Interventional Neurotherapies Organization | 280 | 2027-07-01 | 2026-05-14 |
| Noninvasive CA Monitoring Validation and Autonomic Modulation in Aneurysmal Subarachnoid Hemorrhage Right-Sided Cervical Sympathetic Block at C6, Transcutaneous Auricular Vagal Nerve Stimulation (taVNS) - Subarachnoid Hemorrhage, Aneurysmal, Delayed Cerebral Ischemia | Not applicable | Not yet recruiting | University of Texas Southwestern Medical Center | 300 | 2027-07-01 | 2026-10-16 |
| Comparative Efficacy of Saccadic and Biofeedback Training in Homonymous Hemianopia Biofeedback Fixation Training, Saccadic Reading Training - Hemianopia, Homonymous | Not applicable | Suspended | University of Alabama at Birmingham | 20 | 2027-06-01 | 2026-09-25 |
| Concurrent Trials on Nature-Based Therapy for Inpatients in Dementia and Rehabilitation Medicine Wards Nature Immersion Therapy - Dementia, Acquired Brain Injury Including Stroke | Not applicable | Not yet recruiting | Changi General Hospital | 1600 | 2027-05-01 | 2026-03-23 |
| EDAS Revascularization for Symptomatic Intracranial Atherosclerotic Steno-occlusive Disease Encephaloduroarteriosynangiosis (EDAS), Intensive medical management - Intracranial Atherosclerosis, Intracranial Arterial Stenosis | Not applicable | Not yet recruiting | Cedars-Sinai Medical Center | 170 | 2027-05-01 | 2026-10-22 |
| Intranasal Stem Cells to Treat Perinatal Brain Injury to Combat Cerebral Palsy MSC, marrow, Placebo - Perinatal Arterial Ischemic Stroke, Perinatal Asphyxia | Phase 2 / Phase 3 | Not yet recruiting | UMC Utrecht | 162 | 2027-04-01 | 2026-09-21 |
| Virtual Reality-based Mindfulness Training for Mental Health After Stroke Virtual-reality hypnotherapy device - Stroke (Subacute) | Not applicable | Not yet recruiting | Nicolas Nicastro | 48 | 2027-04-01 | 2026-05-29 |
| The Effectiveness of Patch-Based Screening for Pre-Symptomatic Atrial Fibrillation to Improve Patient Outcome Zio XT® Patch - Atrial Fibrillation | Not applicable | Not yet recruiting | VA Office of Research and Development | 24060 | 2027-03-08 | 2026-06-30 |
| WSO BEAT STROKE Initiative Educational and implementation Neurocardiology tool, No educational or implementation tool will be provided - Stroke, PFO - Patent Foramen Ovale | Not applicable | Not yet recruiting | Luciano A. Sposato | 2400 | 2027-03-01 | 2026-09-18 |
| A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus) Glycerol Tributyrate - MELAS Syndrome, Lebers Hereditory Optic Neuropathy With Extra Ocular Symptoms (LHON-Plus) | Phase 1 / Phase 2 | Not yet recruiting | George Washington University | 24 | 2027-03-01 | 2026-10-05 |
| Feasibility of Real-Time Visual Feedback in Augmented Reality to Reduce Gait Asymmetry Post-Stroke Feasibility of Two Types of Real-Time Visual Feedback in an Augmented Reality - Stroke | Not applicable | Not yet recruiting | McGill University | 20 | 2027-01-15 | 2026-10-07 |
| Dosing and Deployment Trial: A Home-based Optokinetic Treatment Optokinetic stimulation - Spatial Neglect | Not applicable | Not yet recruiting | Duke University | 90 | 2027-01-04 | 2026-06-25 |
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Stroke (7796) · Ischemic Stroke (2541) · Subarachnoid Hemorrhage (501) · Atrial Fibrillation (455) · Cerebral Hemorrhage (431) · Intracranial Aneurysm (390) · Cardiovascular Diseases (369) · Carotid Stenosis (350) · Ischemic Attack, Transient (321) · Paresis (319) · Brain Injuries, Traumatic (288) · Myocardial Infarction (271) · Carotid Artery Diseases (256) · Cognitive Dysfunction (252)
Central Nervous System Diseases (12705) · Vascular Diseases (12677) · Brain Diseases (12666) · Nervous System Diseases (12661) · Cardiovascular Diseases (12435) · Pathological Conditions, Signs and Symptoms (4538) · Pathologic Processes (2764) · Signs and Symptoms (2047) · Stroke (1960) · Neurologic Manifestations (1588) · Hemorrhage (1154) · Heart Diseases (1017) · Intracranial Hemorrhages (999) · Arterial Occlusive Diseases (935)
Transcranial Direct Current Stimulation (217) · Aspirin (186) · Clopidogrel (126) · Transcranial Magnetic Stimulation (104) · Tissue Plasminogen Activator (101) · Standard of Care (100) · Exercise (90) · Rivaroxaban (86) · Mirror Movement Therapy (79) · Control Groups (78) · Saline Solution (73) · Rehabilitation (72) · Sodium Chloride (72) · Tenecteplase (71) · Physical Therapy Modalities (65)
Beijing Tiantan Hospital (184) · Riphah International University (180) · National Taiwan University Hospital (102) · Xuanwu Hospital, Beijing (101) · Chang Gung Memorial Hospital (96) · Assistance Publique - Hôpitaux de Paris (95) · VA Office of Research and Development (95) · Capital Medical University (89) · Second Affiliated Hospital, Zhejiang University, School of Medicine (87) · National Institute of Neurological Disorders and Stroke (NINDS) (80) · Chinese University of Hong Kong (73) · The Hong Kong Polytechnic University (71) · Shirley Ryan AbilityLab (64) · Hospices Civils de Lyon (62) · National Heart, Lung, and Blood Institute (NHLBI) (61)
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Nieto Luis, Master (23) · Jianmin Liu (16) · Ching-yi Wu, ScD (14) · Joon-Ho Shin, MS (14) · Raul G Nogueira, MD (14) · Paolo Bonato, PhD (13)
PMID 33175411, PMID 34813082, PMID 37870112, PMID 31867054, PMID 34184251, PMID 34196963, PMID 35857365, PMID 36700520, PMID 18190818, PMID 34022170, PMID 34487721, PMID 16731270, PMID 21899409, PMID 34515113, PMID 36398903, PMID 2375765, PMID 25671797, PMID 26898852, PMID 32905623, PMID 34695300, PMID 37565307, PMID 24524452, PMID 27657681, PMID 31662037, PMID 32640944, PMID 35349186, PMID 22435369, PMID 25671798, PMID 25882376, PMID 25882510, PMID 29129157, PMID 33447904, PMID 34125952, PMID 35224730, PMID 41855454, PMID 42848972, PMID 1135616, PMID 18815396, PMID 20185783, PMID 22163120, PMID 23713578, PMID 25726502, PMID 25771069, PMID 29098321, PMID 29364767, PMID 29367334, PMID 30739747, PMID 31067369, PMID 34270325, PMID 36289001
2023 (34), 2017 (28), 2018 (28), 2019 (26), 2025 (22), 2016 (19), 2015 (17), 2014 (14), 2009 (9), 2008 (8), P20GM109040 (8), P50NS044148 (7), U10HD021364 (7), U10HD021385 (7), U10HD027851 (7)