109 completed, 33 unknown, 25 recruiting, 16 terminated. 87 Not applicable, 27 Phase 3, 22 Phase 4, 16 Phase 2, 1 Phase 1.
Follow Atrial Flutter: new trials by email Literature Review of Atrial Flutter trials Research Report on Atrial Flutter
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Home Monitor for AA Burden Detection IIT in TWN Paroxysmal Atrial Fibrillation (PAF), Atrial Flutter | Not yet recruiting | National Taiwan University Hospital | 30 | 2026-12-01 | 2026-10-07 | |
| Strategies for the Management of Atrial Fibrillation in patiEnts Receiving Dialysis 2 (SAFE-D2) Eliquis, No oral anticoagulation - Atrial Fibrillation, Atrial Flutter | Phase 3 | Not yet recruiting | Unity Health Toronto | 848 | 2026-11-01 | 2026-08-21 |
| MAGNEsium With meToprolol for Rate Control In Atrial Fibrillation Magnesium Sulfate 2g, Magnesium Sulfate 4g, Saline (0.9% NaCl) - Atrial Flutter With Rapid Ventricular Response | Phase 3 | Not yet recruiting | Wake Forest University Health Sciences | 196 | 2026-10-01 | 2026-06-29 |
| Head-to-Head (H2H) Comparison of Ambulatory Cardiac ECG Monitors in Japan Application of ambulatory cardiac monitor - Atrial Fibrillation (AF), Atrial Flutter | Not applicable | Not yet recruiting | iRhythm Technologies, Inc. | 130 | 2026-09-30 | 2026-10-19 |
| Cardiologist-Administered Midazolam vs. Anaesthesiologist-Assisted Propofol Sedation For Transoesophageal Echocardiography-Guided Cardioversion of Atrial Fibrillation One-step cardiologist-only midazolam sedation, Two-step anaesthesiologist-assisted propofol sedation - Atrial Fibrillation (AF), Atrial Flutter | Phase 4 | Not yet recruiting | Gødstrup Hospital | 220 | 2026-09-01 | 2026-07-08 |
| HeartBeam ECG Registry Electrocardiogram (ECG) - Atrial Fibrillation, Atrial Flutter | Recruiting | HeartBeam, Inc. | 600 | 2026-03-30 | 2026-07-20 | |
| Feasibility Study on the VERAFEYE Imaging and Navigation System for Guided Catheter Ablation Procedures VERAFEYE Imaging and Guidance System - Atrial Fibrillation, Atrial Flutter | Not applicable | Recruiting | LUMA Vision Ltd. | 50 | 2026-03-03 | 2026-09-15 |
| Intra-abdominal Pressure (IAP) During PFA Treatment of A-fib/ A-Flutter Accuryn Foley catheter device - Intra-Abdominal Hypertension | Not applicable | Recruiting | Wake Forest University Health Sciences | 50 | 2026-03-03 | 2026-03-19 |
| Anatomical Navigation for Guided Electrophysiology in AFL and AFib VERAFEYE Anatomic Guidance System - Atrial Fibrillation, Atrial Flutter | Not applicable | Recruiting | LUMA Vision Ltd. | 50 | 2026-01-29 | 2026-10-22 |
| Pulsed-Field Ablation for Recurrent Atypical Atrial Flutter Point-by-point pulsed-field catheter ablation - Atypical Atrial Flutter, Atrial Flutter | Not applicable | Enrolling by invitation | Taipei Veterans General Hospital, Taiwan | 30 | 2026-01-09 | 2026-02-17 |
| Detection of Atrial Fibrillation Through Voice Signal Processing Sauti - Atrial Fibrillation (AF), Atrial Flutter | Not yet recruiting | Vital Audio Inc | 40 | 2025-10-15 | 2025-10-08 | |
| Beta-blockers for Prevention of Supraventricular Arrhythmia Following PFO Closure Beta-blocker treatment group, Non-treatment group - Atrial Fibrillation, Atrial Flutter | Not applicable | Not yet recruiting | Yonsei University | 350 | 2025-09-01 | 2025-08-14 |
| Empiric Pulsed Field Pulmonary Vein Isolation During Atrial Tachycardia Ablation in Adults With Congenital Heart Disease Pulsed field ablation using a pentaspline ablation catheter - Atrial Fibrillation, Atrial Tachycardia | Not applicable | Withdrawn | Boston Children's Hospital | 2025-07-01 | 2026-07-14 | |
| Left Atrial Imaging Prior to Cardioversion: Leveraging Computed Tomography to Rule Out Thrombus in The Emergency Department (LA CLOTTED) Cardiac computed tomography angiography, Standard of care management - Atrial Fibrillation (AF), Atrial Flutter | Not applicable | Recruiting | Ottawa Heart Institute Research Corporation | 190 | 2025-06-15 | 2026-06-09 |
| Repeat Ablation of Persistent Atrial Fibrillation, Including Mitral Isthmus Catheter Ablation, With the FARAPULSE Pulsed Field Ablation System FARAPULSE™ Pulsed Field Ablation System - Persistent Atrial Fibrillation | Not applicable | Active not recruiting | Boston Scientific Corporation | 376 | 2025-06-03 | 2026-09-24 |
| Oral Bisoprolol Vs IV Diltiazem in Atrial Fibrillation or Flutter With Rapid Ventricular Rate. Oral Bisoprolol, Intravenous Diltiazem - Atrial Fibrillation With Rapid Ventricular Response, Atrial Flutter With Rapid Ventricular Response | Phase 3 | Not yet recruiting | Oman Medical Speciality Board | 60 | 2025-04-01 | 2025-03-14 |
| Pulmonary Vein Isolation in Typical Atrial Flutter and Heart Failure Pulmonary vein isolation plus cavo-tricuspid isthmus ablation, Cavo-tricuspid isthmus ablation - Atrial Flutter Typical, Heart Failure | Not applicable | Not yet recruiting | The First Affiliated Hospital with Nanjing Medical University | 168 | 2025-03-01 | 2025-02-10 |
| Intracardiac Echocardiography-Guided Cavotricuspid Isthmus Ablation With a Circular-Shaped Pulsed Field Ablation Catheter ICE-guided CTI ablation with PFA - Atrial Fibrillation (AF), Atrial Flutter | Recruiting | Beijing Anzhen Hospital | 150 | 2025-01-15 | 2026-01-20 | |
| Vitamin K AntagonISt, Factor Xa Inhibitor or No Anticoagulation in Atrial Fibrillation and DIalytic End-stage Renal DiseasE (VISIONAIRE) Anticoagulant Oral - Atrium; Fibrillation, Chronic Kidney Diseases | Phase 4 | Recruiting | Hospital Sirio-Libanes | 1500 | 2024-12-18 | 2025-02-21 |
| Genetic Characterization of Patients With Arrhythmia-Induced Cardiomyopathy Arrhythmia, Cardiomyopathy | Recruiting | Hospital Universitario 12 de Octubre | 109 | 2024-12-01 | 2026-09-15 |
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Atrial Fibrillation (151) · Arrhythmias, Cardiac (42) · Tachycardia, Ventricular (15) · Stroke (14) · Tachycardia, Supraventricular (10) · Ventricular Premature Complexes (9) · Heart Failure (8) · Tachycardia (8) · Atrial Premature Complexes (6) · Bradycardia (5) · Myocardial Infarction (5) · Atrioventricular Block (4) · Cardiovascular Diseases (4) · Embolism (4)
Pathologic Processes (207) · Pathological Conditions, Signs and Symptoms (207) · Heart Diseases (204) · Cardiovascular Diseases (203) · Arrhythmias, Cardiac (165) · Cardiac Conduction System Disease (32) · Vascular Diseases (26) · Nervous System Diseases (19) · Tachycardia (19) · Brain Diseases (16) · Central Nervous System Diseases (16) · Cerebrovascular Disorders (16) · Cardiac Complexes, Premature (11) · Embolism and Thrombosis (9) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (7)
Catheter Ablation (9) · Warfarin (6) · Electric Countershock (5) · Amiodarone (4) · Dabigatran (4) · Radiofrequency Ablation (4) · apixaban (4) · Dronedarone (3) · Metoprolol (3) · edoxaban (3) · vernakalant (3) · Adrenergic beta-Antagonists (2) · Diltiazem (2) · Echocardiography (2) · Electrocardiography (2)
Boston Scientific Corporation (8) · Emory University (5) · Sanofi (5) · Wake Forest University Health Sciences (4) · Adagio Medical (3) · Bristol-Myers Squibb (3) · Medtronic Cardiac Ablation Solutions (3) · Ottawa Hospital Research Institute (3) · Population Health Research Institute (3) · Solvay Pharmaceuticals (3) · Unity Health Toronto (3) · University of Leipzig (3) · Aarhus University Hospital Skejby (2) · Abbott Medical Devices (2) · Acutus Medical (2)
United States (74) · Canada (32) · Germany (29) · Czechia (16) · Denmark (15) · Netherlands (15) · Belgium (13) · Poland (13) · Russia (13) · France (12) · Italy (11) · Spain (11) · Sweden (11) · United Kingdom (11) · Australia (10)
David Conen, MD, MPH (2) · Ian Stiell, MD (2) · Samuel C. Dudley, Jr., MD, PhD (2) · Stephan Willems, MD (2) · Alexander Spiel, Priv. Doz. (1) · Allan Skanes, MD, FRCPC (1) · Alok Kapoor, MD (1) · Anders S. Schmidt, MB (1) · Andreas Metzner, MD (1)
PMID 35717354, PMID 17804843, PMID 22171925, PMID 34196991, PMID 40150915, PMID 12875419, PMID 15089986, PMID 15093885, PMID 15911947, PMID 16380589, PMID 17599958, PMID 18612186, PMID 18811813, PMID 19213680, PMID 19616669, PMID 19804553, PMID 19948506, PMID 20009074, PMID 20436046, PMID 20663073, PMID 20876601, PMID 21083927, PMID 21091964, PMID 21232631, PMID 21296333, PMID 21576129, PMID 21714971, PMID 21870978, PMID 22032709, PMID 22291438, PMID 22572202, PMID 22770643, PMID 23036896, PMID 23101718, PMID 23379836, PMID 23468405, PMID 23563134, PMID 23575255, PMID 23585253, PMID 23636870, PMID 23640971, PMID 24016506, PMID 24016507, PMID 24055845, PMID 24058180, PMID 24063921, PMID 24211508, PMID 24226808, PMID 24251361, PMID 24440330
2004 (3), 2016 (2), 1UL1TR001425-01 (1), R21MD017646 (1), U01HL088942 (1)