74 completed, 21 terminated, 17 recruiting, 14 unknown. 80 Not applicable, 18 Phase 4, 10 Phase 3, 6 Phase 1, 4 Phase 2.
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Predict Atrial Fibrillation (AF) Burden in Participants With PAF and PsAF Treated With the VARIPULSE™ PFA Catheter VARIPULSE Catheter System (PVI), VARIPULSE Catheter System (PVI and PWI) - Atrial Fibrillation | Not applicable | Not yet recruiting | Biosense Webster, Inc. | 2300 | 2026-10-30 | 2026-09-15 |
| A Study of Dual Energy THERMOCOOL SMARTTOUCH™ SF Catheter With TRUPULSE™ Generator in Persistent Atrial Fibrillation Radiofrequency/Pulsed Field Ablation - Atrial Fibrillation | Not applicable | Not yet recruiting | Biosense Webster, Inc. | 150 | 2026-09-24 | 2026-09-29 |
| A Study of VARIPULSE Catheter in Participants With Persistent Atrial Fibrillation Undergoing Pulmonary Vein and Superior Vena Cava Isolation VARIPULSE Catheter System, LAAO Device - Atrial Fibrillation | Not applicable | Recruiting | Biosense Webster, Inc. | 1070 | 2026-08-26 | 2026-09-25 |
| A Study of Dual Energy THERMOCOOL SMARTTOUCH™ SF Catheter With the TRUPULSE™ Generator for Treatment of Ventricular Arrhythmias Radiofrequency/Pulsed Field Ablation System - Arrhythmias, Cardiac | Not applicable | Recruiting | Biosense Webster, Inc. | 90 | 2026-07-08 | 2026-09-25 |
| A Study of VARIPULSE Catheter and TRUPULSE Generator With VARIPULSE PRO Software in Participants With PsAF Pulsed Field Ablation System - Atrial Fibrillation | Not applicable | Recruiting | Biosense Webster, Inc. | 50 | 2026-05-19 | 2026-09-25 |
| A Study of VARIPULSE Pulsed Field Ablation (PFA) Catheter and FARAWAVE PFA Catheter in the Treatment of Participants With Persistent Atrial Fibrillation VARIPULSE Catheter, FARAWAVE Catheter - Atrial Fibrillation | Not applicable | Recruiting | Biosense Webster, Inc. | 566 | 2026-04-02 | 2026-09-15 |
| A Study of VARIPULSE Catheter and TRUPULSE Generator With VARIPULSE Pro Software in Participants With PAF or PsAF Pulsed Field Ablation System - Atrial Fibrillation | Not applicable | Recruiting | Biosense Webster, Inc. | 50 | 2026-03-23 | 2026-09-25 |
| Pulsed-Field Ablation for Recurrent Atypical Atrial Flutter Point-by-point pulsed-field catheter ablation - Atypical Atrial Flutter, Atrial Flutter | Not applicable | Enrolling by invitation | Taipei Veterans General Hospital, Taiwan | 30 | 2026-01-09 | 2026-02-17 |
| A Prospective Observational Study Evaluating the Incidence of Silent Cerebral Lesions and Procedural Safety Following Atrial Fibrillation Ablation Using the VARIPULSE™ Pulsed Field Ablation System Atrial Fibrillation (AF) | Recruiting | Seoul National University Hospital | 40 | 2025-12-26 | 2026-01-23 | |
| A Study Assessing Long-Term Safety and Effectiveness in Treatment Management of Atrial Fibrillation With VARIPULSE Catheter System Pulsed Field Ablation by VARIPULSE Catheter with TRUPULSE Generator - Atrial Fibrillation | Not applicable | Recruiting | Biosense Webster, Inc. | 276 | 2025-10-21 | 2026-09-30 |
| Durability of Pulmonary Vein Isolation Using a Variable-Loop Biphasic Pulsed Field Ablation Catheter in Patients With Paroxysmal Atrial Fibrillation Pulmonary vein isolation with the VariPulse catheter - Paroxysmal AF | Not applicable | Active not recruiting | Erasmus Medical Center | 20 | 2025-09-27 | 2026-09-11 |
| A Study Assessing Arrhythmia Mapping With a Multi-Electrode Mapping Catheter Paddle-Shaped, High-Density, Multi-Electrode Mapping Catheter - Scar-related Atrial Tachycardia, Persistent Atrial Fibrillation | Not applicable | Recruiting | Biosense Webster, Inc. | 90 | 2025-09-15 | 2026-09-28 |
| Evaluation of the Impact of Pulsed Field Ablation on Autonomic Nervous System Modulation in Paroxysmal Atrial Fibrillation PF-only PVI, Hybrid PVI, RF-only PVI - Atrial Fibrillation (AF), Paroxysmal AF | Not applicable | Recruiting | VZW Cardiovascular Research Center Aalst | 105 | 2025-01-29 | 2025-07-10 |
| Left Atrial Posterior Wall and Mitral Isthmus PF Ablation in Non-Paroxysmal AF Patients pulsed-field ablation - Atrial Fibrillation (AF) | Recruiting | Charles University, Czech Republic | 50 | 2025-01-01 | 2025-11-21 | |
| Ablation-Index Guided Scar-Mediated Ventricular Tachycardia Ablation in Patients With Ischemic Cardiomyopathy Ablation-index guided ventricular tachycardia ablation, Ventricular tachycardia ablation with no AI-guidance - Ventricular Tachycardia, Ischemic Cardiomyopathy | Not applicable | Recruiting | Rush University Medical Center | 100 | 2024-10-23 | 2025-09-22 |
| Esophageal Temperature During PVI Using Q-DOT Micro QDOT Micro ablation catheter, ST SF ablation catheter - Atrial Fibrillation Paroxysmal | Not applicable | Recruiting | Cedars-Sinai Medical Center | 30 | 2024-10-04 | 2025-10-28 |
| Exploratory Safety and Effectiveness Evaluation of Pulsed Field Ablation (PFA) by Balloon Catheter With TRUPULSE Generator for Treatment of Paroxysmal Atrial Fibrillation (PAF) Pulsed Field Ablation by a Balloon Catheter with the TRUPULSE Generator - Atrial Fibrillation | Not applicable | Withdrawn | Biosense Webster, Inc. | 2024-08-17 | 2025-02-04 | |
| A Study of Assessment on Safety and Effectiveness of BWI Pulsed Field Ablation With OMNYPULSE Catheter for the Treatment of Paroxysmal Atrial Fibrillation (PAF) OMNYPULSE™ Catheter with the TRUPULSE Generator - Atrial Fibrillation | Not applicable | Active not recruiting | Biosense Webster, Inc. | 354 | 2024-06-28 | 2026-09-25 |
| Real-world Safety and Effectiveness Registry of Catheter Ablation of Paroxysmal Atrial Fibrillation as Initial Control Therapy With the Thermocool SmartTouch SF Catheter (A Sub-study of REAL AF Registry) Ablation - Paroxysmal Atrial Fibrillation (PAF) | Active not recruiting | Heart Rhythm Clinical and Research Solutions, LLC | 344 | 2024-04-01 | 2025-10-31 | |
| A Study of the THERMOCOOL SMARTTOUCH Surround Flow (SF) Catheter With the TRUPULSE Generator for Treatment of Drug Refractory Symptomatic PAFOUS Pulsed Field (PF) /Radiofrequency (RF) Catheter ablation - Atrial Fibrillation | Not applicable | Completed | Biosense Webster, Inc. | 136 | 2024-02-28 | 2026-10-16 |
Showing 20 of 140. Sign in to see all of them.
Atrial Fibrillation (96) · Tachycardia, Ventricular (24) · Arrhythmias, Cardiac (20) · Heart Diseases (7) · Atrial Flutter (6) · Ventricular Premature Complexes (6) · Cardiomyopathies (4) · Heart Failure (4) · Myocardial Infarction (4) · Myocardial Ischemia (3) · Cardiovascular Diseases (2) · Coronary Artery Disease (2) · Hypertension, Renal (2) · Pathologic Processes (2) · Syncope (2)
Catheter Ablation (22) · Anti-Arrhythmia Agents (8) · Amiodarone (6) · Sotalol (5) · Radiofrequency Ablation (4) · Flecainide (2) · Radionuclide Generators (2) · dofetilide (2) · 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific) (1) · Calcium Channel Blockers (1) · Cardiac Imaging Techniques (1) · Electroporation (1) · Irreversible Electroporation Therapy (1) · Nuclear Receptor Subfamily 4, Group A, Member 2 (1) · Propafenone (1)
United States (49) · Belgium (18) · Italy (16) · Germany (15) · Canada (14) · Czechia (13) · United Kingdom (11) · Denmark (9) · France (8) · Austria (7) · Lithuania (7) · Brazil (6) · China (6) · Australia (5) · Netherlands (5)
Biosense Webster, Inc. Clinical Trial (14) · Andrea Natale, MD (7) · Vivek Reddy, MD (7) · Alexander Mazur, MD (3) · Anshul Patel, MD (3) · David Wilber, MD (3) · Dhanunjaya Lakkireddy, MD (3) · Francis Marchlinski, MD (3) · Robert Fishel, MD (3) · Saumil Oza, MD (3) · Srinivas Dukkipati, MD (3) · Abdi Rasekh, MD (2) · Alan Wimmer, MD (2) · Andy Tran, MD (2)
PMID 19307477, PMID 22386883, PMID 31698933, PMID 35333095, PMID 11343485, PMID 15313941, PMID 15653029, PMID 16302895, PMID 16344401, PMID 16782716, PMID 19029470, PMID 19602027, PMID 19808418, PMID 19843914, PMID 20103757, PMID 20206320, PMID 20339034, PMID 20601148, PMID 20817018, PMID 20940250, PMID 21539635, PMID 21955090, PMID 21965530, PMID 22236222, PMID 22550126, PMID 22922413, PMID 24135832, PMID 24425420, PMID 25125294, PMID 25618742, PMID 25638698, PMID 26041872, PMID 26260733, PMID 26272524, PMID 26763226, PMID 26868693, PMID 27149033, PMID 29305400, PMID 29315382, PMID 29754661, PMID 29759434, PMID 29759747, PMID 30354288, PMID 30874716, PMID 30874766, PMID 30943196, PMID 31320006, PMID 32087356, PMID 32586583, PMID 32819531
2019 (1), U01HL089709 (1)