12 completed, 10 unknown, 6 terminated, 3 recruiting. 16 Phase 4, 8 Not applicable, 7 Phase 3, 1 Phase 2.
Follow Anti-Arrhythmia Agents: new trials by email Literature Review of Anti-Arrhythmia Agents trials Research Report on Anti-Arrhythmia Agents
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Early Treatment of Atrial Fibrillation for Stroke Prevention Trial in Acute STROKE Medical or interventional therapy for rhythm control in atrial fibrillation (antiarrhythmic drugs, ablation, electric cardio version), Usual care for atrial fibrillation - Acute Ischemic Stroke, Atrial Fibrillation | Phase 3 | Recruiting | Universitätsklinikum Hamburg-Eppendorf | 1746 | 2025-11-06 | 2026-05-18 |
| The Safety and Efficacy of Pulsed Field Ablation for Patients With Persistent Atrial Fibrillation Comorbid With HFpEF. pulsed field ablation, antiarrhythmic drug - Cardiovascular Diseases, Heart Failure | Not applicable | Enrolling by invitation | Affiliated Hospital of Nantong University | 158 | 2025-06-01 | 2025-07-22 |
| Evaluation of Cardioverter Capacity of Amiodarone Pre-electrical Cardioversion in Persistent Atrial Fibrillation Amiodarone (Antiarrhythmic drug) - Atrial Fibrillation (AF) | Phase 4 | Not yet recruiting | Institut Investigacio Sanitaria Pere Virgili | 122 | 2024-12-10 | 2024-12-02 |
| The Use of Antiarrhythmic Drugs in Pediatrics Antiarrhythmic drugs - Antiarrhythmic Drug Adverse Reaction | Unknown | Assiut University | 158 | 2024-04-01 | 2024-02-22 | |
| EfFect of Ablation of Persistent AtriaL Fibrillation on COgNitive Function in Individuals With Mild Cognitive Impairment Atrial fibrillation ablation + antiarrhythmic drugs, Antiarrhythmic drug - Mild Cognitive Impairment, Persistent Atrial Fibrillation | Not applicable | Recruiting | Poitiers University Hospital | 120 | 2023-04-21 | 2026-01-23 |
| CardiaMend and Amiodarone for the Prevention of POAF CardiaMend with antiarrhythmic - POAF, Atrial Fibrillation | Not applicable | Unknown | Saint Alphonsus Regional Medical Center | 30 | 2023-01-01 | 2022-12-08 |
| CAB Versus Medical Therapy in Patients With AF and HF With Different EF Categories Antiarrhythmic drug Therapy, cryoballoon ablation - Cardiovascular Diseases | Unknown | Affiliated Hospital of Nantong University | 200 | 2022-05-01 | 2023-06-15 | |
| Use of Antiarrhythmic Drugs in Pediatrics Antiarrhythmic drug - Antiarrhythmic Toxicity | Unknown | Assiut University | 100 | 2021-10-01 | 2021-05-06 | |
| Treatment Of Atrial Fibrillation In Preserved Cardiac Function Heart Failure Catheter ablation, Rate or Rhythm control antiarrhythmic drugs for atrial fibrillation, Insertion of CardioMems Hemodynamic monitor - Atrial Fibrillation, Heart Failure | Phase 4 | Unknown | Electrophysiology Research Foundation | 360 | 2020-07-26 | 2024-05-23 |
| MANAGE-VT Registry - MANAGEment of Ventricular Tachycardia Outcomes Registry Ventricular Tachycardia Ablation, ICD Implant, Antiarrhythmic drug - Ventricular Tachycardia | Recruiting | CorVita Science Foundation | 130 | 2020-07-20 | 2024-06-12 | |
| Catheter Ablation Versus Anti-arrhythmic Drugs for Ventricular Tachycardia Ablation, Anti-arrhythmic Drugs (AADs) - Heart Disease Structural Disorder, Ventricular Tachycardia | Not applicable | Active not recruiting | Western Sydney Local Health District | 162 | 2020-07-08 | 2026-03-16 |
| Continuation of Antiarrhythmics Following Ventricular Tachycardia Catheter Ablation Antiarrhythmic drug - Tachycardia, Ventricular, Catheter Ablation | Phase 3 | Terminated | Vanderbilt University Medical Center | 5 | 2019-12-19 | 2022-11-14 |
| First Line Radiofrequency Ablation Versus Antiarrhythmic Drugs for Persistent Atrial Fibrillation Treatment (RAAFT-3) Anti Arrhythmics, Pulmonary Vein Isolation performed by Radio Frequency Catheter Ablation - Atrial Fibrillation | Phase 3 | Completed | University of Pennsylvania | 25 | 2019-09-24 | 2024-11-12 |
| Liraglutide Effect in Atrial Fibrillation Liraglutide, RFM, Anti Arrhythmics - Atrial Fibrillation | Phase 4 | Active not recruiting | University of Miami | 60 | 2019-03-18 | 2026-05-01 |
| Prospective Randomized Clinical Trial for Effect of Stellate Ganglion Block in Medically Refractory Ventricular Tachycardia Antiarrhythmic drug, percutaneous stellate ganglion block (PSGB) - Refractory Ventricular Tachycardia | Not applicable | Unknown | Yonsei University | 20 | 2019-03-01 | 2019-02-11 |
| Prospective Assessment of Premature Ventricular Contractions Suppression in Cardiomyopathy(PAPS) Radiofrequency ablation, Amiodarone (Antiarrhythmic drug) - Ventricular Premature Beats, Contractions, or Systoles, Cardiomyopathies | Phase 4 | Unknown | Hunter Holmes Mcguire Veteran Affairs Medical Center | 5 | 2018-08-01 | 2021-04-14 |
| CRyoAblation vs AntiaRrhythmic Drugs for Persistent Atrial Fibrillation Trial Arctic Front Advance® balloon catheter, Antiarrhythmic drug, Confirm RX heart monitor® (Abbott) - Atrial Fibrillation | Phase 4 | Completed | Hospital San Carlos, Madrid | 196 | 2018-06-27 | 2025-09-15 |
| PROSPECTIVE ANALYSIS BETWEEN AMIODARONE Versus LIDOCAINE IN SVT Antiarrythmic Drugs, Antiarrhythmic drugs - Arrhythmias Ventricular | Phase 4 | Unknown | University of Sao Paulo General Hospital | 80 | 2017-08-02 | 2018-10-24 |
| STOP AF First: Cryoballoon Catheter Ablation in an Antiarrhythmic Drug Naive Paroxysmal Atrial Fibrillation Cryoablation, Antiarrhythmic drug - Atrial Fibrillation, Atrial Fibrillation New Onset | Not applicable | Completed | Medtronic Cardiac Ablation Solutions | 225 | 2017-06-23 | 2025-02-13 |
| Catheter Ablation of Arrhythmias to Improve CRT Response Catheter Ablation, Anti-Arrhythmics - Arrhythmia, Cardiac | Phase 4 | Terminated | Kansas City Heart Rhythm Institute | 2 | 2017-01-23 | 2022-09-10 |
Showing 20 of 36. Sign in to see all of them.
Atrial Fibrillation (23) · Tachycardia, Ventricular (7) · Arrhythmias, Cardiac (5) · Cardiovascular Diseases (4) · Heart Diseases (3) · Cardiomyopathies (2) · Cardiomyopathy, Hypertrophic (2) · Heart Failure (2) · Ventricular Premature Complexes (2) · Arrhythmogenic Right Ventricular Dysplasia, Familial, 1 (1) · Atrial Flutter (1) · Cardiomyopathy, Dilated (1) · Cognitive Dysfunction (1) · Coronary Disease (1) · Death, Sudden, Cardiac (1)
Biosense Webster, Inc. (3) · Affiliated Hospital of Nantong University (2) · Assiut University (2) · Medtronic Cardiac Ablation Solutions (2) · Biosense Webster EMEA (1) · C. R. Bard (1) · CorVita Science Foundation (1) · Electrophysiology Research Foundation (1) · Hospital Clinic of Barcelona (1) · Hospital General Universitario Gregorio Marañon (1) · Hospital San Carlos, Madrid (1) · Hunter Holmes Mcguire Veteran Affairs Medical Center (1) · Institut Investigacio Sanitaria Pere Virgili (1) · Kansas City Heart Rhythm Institute (1) · Kyoto University, Graduate School of Medicine (1)
United States (12) · Germany (4) · Spain (4) · Canada (3) · France (3) · Italy (3) · Australia (2) · Brazil (2) · China (2) · Russia (2) · Switzerland (2) · Argentina (1) · Belgium (1) · Croatia (1) · Czechia (1)
Andrea Natale, MD (2) · Alexandre Soeiro, MD (1) · Angel Arenal, MD (1) · Angel Arenal, MD, PhD (1) · Anne Marie Harcarik (1) · Arvindh Kanagasundram, M.D (1) · David Wilber, MD (1) · Dhanunjaya Lakkireddy, MD (1) · Dietmar Baensch, PhD, MD (1) · Emanuele Bertaglia, MD (1) · Evegny Pokushalou, MD (1) · Evgeny Pokushalov, MD, PhD (1) · Franciszek Walczak, MD, PhD (1) · GianBattista Chierchia, MD (1) · Giuseppe Stabile, MD (1)
PMID 38007219, PMID 12372573, PMID 19029470, PMID 20103757, PMID 20940250, PMID 23748210, PMID 24135832, PMID 25638698, PMID 26472995, PMID 33197158, PMID 34508694, PMID 35422240, PMID 37366571, PMID 39445764, PMID 42153760, PMID 42159524
2023 (1), R34HL138110 (1), U01HL045700 (1)