56 completed, 32 unknown, 10 recruiting, 8 terminated. 34 Not applicable, 25 Phase 3, 24 Phase 2, 19 Phase 4, 9 Phase 1.
Follow Botulinum Toxins: new trials by email Literature Review of Botulinum Toxins trials Research Report on Botulinum Toxins
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of Botulinum TOXin Type A in the Treatment of Buerger's Disease BOTOX INJECTION - Buerger Disease, Raynaud Syndrome | Phase 3 | Not yet recruiting | University Hospital, Toulouse | 8 | 2027-01-01 | 2026-07-23 |
| Extracorporeal Shockwave Therapy as an Additional Treatment for Spasticity Secondary to Spinal Cord Injury Focused extracorporeal shockwave therapy, Botulinum toxin, Sham - Spinal Cord Injury, Spasticity | Phase 2 | Recruiting | Kessler Foundation | 30 | 2026-09-21 | 2026-10-26 |
| Botulinum Toxin in the Palatopharyngeal Muscle for the Treatment of Obstructive Sleep Apnea BOTULINUM TOXIN IN THE PALATOPHARYGEUS MUSCLE - Sleep Apnea Syndrome, Obstructive, Sleep Apnea Syndrome (OSAS) | Phase 2 | Not yet recruiting | Hospital Felicio Rocho | 20 | 2026-04-05 | 2026-02-10 |
| Individualised Cryoneurolysis to Treat Pain in the Context of Spasticity in the Upper and Lower Extremities Cryoneurolysis, Botulinum toxin - Centreal Neurological Condition, Acquired Brain Injury (Including Stroke) | Phase 4 | Recruiting | Oxford University Hospitals NHS Trust | 50 | 2025-12-02 | 2025-12-26 |
| A Novel Medical System for Quantitative Diagnosis and Personalized Precision Botulinum Neurotoxin Injection in Chronic Pelvic Pain Management High Density Surface Electromyographic, precision botulinum neurotoxin injection guidance medical device, Botulinum Neurotoxin - Interstitial Cystitis, Chronic Pain | Early Phase 1 | Not yet recruiting | HillMed Inc. | 46 | 2025-09-15 | 2025-08-19 |
| EMG-Based Evaluation of Occlusal Splint and Masseter Botox Effects on Head and Neck Muscles Botulinum toxin injection, Occlusal splint, Botulinum toxin + Occlusal splint combined - Myofascial Pain Syndrome (MPS), Masticatory Muscle Pain | Phase 4 | Recruiting | Istanbul University | 56 | 2025-09-01 | 2025-07-24 |
| Botulinum Toxin Injection After Sternotomies to Improve Scar Aspect and Impact Botulinum toxin injection - Sternotomy Closure,Open Heart Surgery | Phase 3 | Not yet recruiting | University Hospital, Bordeaux | 50 | 2025-07-05 | 2025-06-10 |
| Botulinum Toxin Injection in Reducing Scar Following Cheilorrhaphy. Modified Millard rotation advancement flap technique, botulinum toxin injection (BTX A) before surgical intervention - Unilateral Cleft Lip | Not applicable | Completed | Mansoura University | 32 | 2025-03-15 | 2026-07-22 |
| Botox for Chronic Pelvic Pain Botulinum neurotoxin, High Density Surface Electromyographic, precision botulinum neurotoxin injection guidance medical device - Pelvic Floor Disorders | Phase 1 | Recruiting | University of Miami | 30 | 2025-02-24 | 2026-06-17 |
| Factors Determining the Efficacy of Botulinum Toxin for Arm Tremor in Dystonia Polymyography, Muscle ultrasound, (Functional) magnetic resonance imaging - Dystonic Tremor Syndrome | Phase 4 | Active not recruiting | Radboud University Medical Center | 60 | 2025-01-01 | 2026-08-14 |
| Efficacy of One or Two Botulinum Toxin Injections in the Treatment of Chronic Lateral Epicondylalgia: a Retrospective Study (EPITOX) Botulinum toxin injection - Lateral Epicondylitis | Unknown | University Hospital, Brest | 80 | 2024-11-01 | 2025-01-09 | |
| EMG-guided Botox Injection Versus Conventional Botox Injection in Gummy Smile Patients Botox injection, EMG, Zinc Supplement - Excessive Gingival Display | Not applicable | Recruiting | Cairo University | 32 | 2024-11-01 | 2026-03-20 |
| Cyclops Syndrome After Anterior Cruciate Ligament Reconstruction Botulinum toxin, Placebo - Hamstring Contractures | Phase 3 | Terminated | GCS Ramsay Santé pour l'Enseignement et la Recherche | 13 | 2024-07-18 | 2026-06-05 |
| Strategy to Adapt Botulinum Toxin Doses in Dystonia Botulinum toxin - Dystonia | Unknown | Central Hospital, Nancy, France | 100 | 2024-05-01 | 2024-04-26 | |
| Ultrasound-guided Botulinum Toxin Injection on Cricopharyngeal Muscle Dysfunction Injectable Type A Botulinum Toxin - Cricopharyngeal Achalasia | Not applicable | Unknown | Zeng Changhao | 30 | 2024-02-28 | 2024-03-07 |
| Evaluation of Tibial Nerve Selective Neurotomy Compared to Botulinum Toxin Injections for Spastic Foot Treatment in Post-stroke Patients According to a Goal-centered Approach Tibial nerve selective neurotomy, Botulinum toxin injection - Post Stroke Seizure, Spastic Foot | Not applicable | Recruiting | Hospices Civils de Lyon | 60 | 2024-01-02 | 2025-07-14 |
| Injection of Botulinum Toxin for Thumb Carpometacarpal Arthritis Botulinum toxin, Standard-of-care corticosteroid injections - Carpometacarpal Sprain, Thumb Sprain | Phase 3 | Recruiting | Rhode Island Hospital | 50 | 2023-08-27 | 2024-11-20 |
| Effect of Different Treatment Techniques on Masseter Muscle Thickness Occlusal splint, preventive advice, Botulinum toxin - Bruxism, Masseter Muscle Hypertrophy | Not applicable | Completed | Zonguldak Bulent Ecevit University | 48 | 2023-04-03 | 2024-09-19 |
| Intrapapillary Botulinum Toxin Injection for PREvention of Post-surgical PAncREactic Fistula botulinum toxin injection - Distal Pancreatectomy, Postoperative Pancreatic Fistula | Not applicable | Recruiting | Assistance Publique - Hôpitaux de Paris | 460 | 2023-03-27 | 2023-07-10 |
| Assessment of Botulinum Toxin Injection for Treatment of Temporomandibular Joint Dislocation Botulinum toxin type A - Dislocation of Temporomandibular Joint TMJ, Subluxation of Temporomandibular Joint | Not applicable | Unknown | Cairo University | 28 | 2022-12-30 | 2023-05-22 |
Showing 20 of 116. Sign in to see all of them.
Muscle Spasticity (13) · Stroke (13) · Cicatrix (6) · Torticollis (6) · Bruxism (5) · Dystonia (4) · Pain (4) · Atrial Fibrillation (3) · Blepharospasm (3) · Cerebral Palsy (3) · Cicatrix, Hypertrophic (3) · Essential Tremor (3) · Raynaud Disease (3) · Botulism (2) · Brain Injuries, Traumatic (2)
Chang Gung Memorial Hospital (5) · Galderma R&D (5) · Meshalkin Research Institute of Pathology of Circulation (5) · Assistance Publique - Hôpitaux de Paris (3) · Cairo University (3) · Mansoura University (3) · Mentor Worldwide, LLC (3) · Emory University (2) · Henry Ford Health System (2) · Hospices Civils de Lyon (2) · Johns Hopkins University (2) · National Institute of Neurological Disorders and Stroke (NINDS) (2) · University Hospital, Grenoble (2) · University of Miami (2) · Asir John Samuel (1)
United States (45) · France (16) · Taiwan (8) · Egypt (7) · Russia (5) · Turkey (Türkiye) (5) · Canada (4) · Belgium (3) · Norway (3) · United Kingdom (3) · Brazil (2) · Spain (2) · Sweden (2) · China (1) · Denmark (1)
Pong Ya-Ping, MD (3) · Corey Maas, MD (2) · David Ozog, MD (2) · Philippe Kestemont, MD (2) · Alexandre Hardy, MD (1) · Anke Snijders, PhD (1) · Aparna Wagle Shukla (1) · Barbara I Karp, M.D. (1) · Barham K AbuDayyeh, MD (1) · Basel Saeed Shamaa, Master's (1) · Benjamin Bollens, Doctor (1) · Celia F Stewart, Ph.D. (1)
PMID 10077078, PMID 10395629, PMID 10896696, PMID 11242330, PMID 11348456, PMID 12845617, PMID 1451966, PMID 14769323, PMID 15162347, PMID 15657647, PMID 16777777, PMID 18065878, PMID 18534768, PMID 18555763, PMID 18843115, PMID 19154823, PMID 19215252, PMID 19341651, PMID 19737151, PMID 19802513, PMID 20009818, PMID 20086074, PMID 20440184, PMID 21300635, PMID 21332916, PMID 21556039, PMID 21699810, PMID 21757278, PMID 22090252, PMID 22177632, PMID 22616652, PMID 22907286, PMID 23027220, PMID 23102873, PMID 23113942, PMID 24501476, PMID 24852565, PMID 24898579, PMID 25515292, PMID 25536218, PMID 25592185, PMID 25596103, PMID 26044342, PMID 26486855, PMID 26748219, PMID 27639820, PMID 28426903, PMID 28539239, PMID 28654594, PMID 29401161
2004 (1), 2017 (1), K08AR080844 (1), R01DK133800 (1), R21HD048972 (1), R21HD123083 (1), U10EY011751 (1)