Hypertension: Clinical Trials

4602 completed, 1030 unknown, 662 recruiting, 390 terminated. 2976 Not applicable, 855 Phase 3, 841 Phase 4, 640 Phase 2, 480 Phase 1.

By phase and status

Phase	Trials	Status
Not applicable	2976	Completed 1729, Unknown 417, Recruiting 311, Not yet recruiting 167, Active not recruiting 124, Terminated 108, Withdrawn 74, Enrolling by invitation 36, Suspended 10
Phase 3	855	Completed 631, Unknown 73, Terminated 66, Withdrawn 30, Recruiting 24, Not yet recruiting 13, Active not recruiting 12, Enrolling by invitation 4, Suspended 2
Phase 4	841	Completed 545, Unknown 142, Terminated 66, Recruiting 34, Withdrawn 30, Not yet recruiting 14, Active not recruiting 4, Enrolling by invitation 4, Suspended 2
Phase 2	640	Completed 386, Terminated 91, Unknown 50, Recruiting 41, Withdrawn 34, Not yet recruiting 20, Active not recruiting 15, Enrolling by invitation 3
Phase 1	480	Completed 343, Unknown 43, Recruiting 27, Terminated 26, Not yet recruiting 20, Withdrawn 16, Active not recruiting 5
Early Phase 1	64	Completed 20, Unknown 13, Recruiting 11, Terminated 11, Not yet recruiting 3, Active not recruiting 2, Enrolling by invitation 2, Withdrawn 2

Follow Hypertension: new trials by email Literature Review of Hypertension trials Research Report on Hypertension

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Inhibiting GABA Transaminase to Relieve Obesity Induced Hyperinsulinemia and Insulin Resistance Vigabatrin Pill, Placebo oral tablet - Hyperinsulinism, Insulin Resistance	Phase 2	Withdrawn	University of Arizona		2030-04-15	2025-07-30
PAtient Similarity for Decision-Making in Prevention of Cardiovascular Toxicity (PACT): A Feasibility Study Clinical Decision Aid, Standard Care - Heart Failure, Coronary Artery Disease		Not yet recruiting	Medical College of Wisconsin	60	2027-12-01	2026-11-03
Veteran Centered Meal Intervention in Chronic Kidney Disease Medically tailored meals (MTMs) - Chronic Kidney Disease	Not applicable	Not yet recruiting	VA Office of Research and Development	100	2027-10-01	2026-09-03
Implementation Support for HEARTS-Based Hypertension and Diabetes Care in Guatemala HEARTS implementation support, Routine HEARTS implementation - Hypertension (HTN), Type 2 Diabetes	Not applicable	Not yet recruiting	University of Michigan	1440	2027-10-01	2026-11-12
Mobile Health Management of Hypertension mHealth Coaching Intervention, Enhanced Usual Care - Hypertension	Not applicable	Not yet recruiting	University of Chicago	40	2027-09-01	2026-08-10
Community Health Worker Nutrition Self-Management Support for Cardio-Kidney-Metabolic Health INTEGRATE-CHW, Usual Care - Hypertension (HTN), CKD - Chronic Kidney Disease	Not applicable	Not yet recruiting	Florida International University	200	2027-07-15	2026-11-05
Know Your Pressures NYC Virtual Automated Navigator Intervention with Health Education, Usual Care - Glaucoma, Hypertension	Not applicable	Not yet recruiting	Columbia University	7085	2027-07-01	2026-08-25
A Study to Evaluate the Best Ways to Implement a Community Health Worker-supported Telehealth Program for Managing High Blood Pressure in Kenya Core Strategies, Enhanced Strategies - Hypertension (HTN), Telehealth	Not applicable	Not yet recruiting	University of California, San Francisco	3200	2027-06-01	2026-11-09
A MOST Framework Trial Evaluating the MOst effectiVe Exercise Types for Blood Pressure Control Core intervention (Fitbit tracking and BP health education), Aerobic training (AT), Dynamic resistance training (DRT) - Hypertension	Not applicable	Not yet recruiting	Northwestern University	264	2027-05-01	2026-11-06
Clinical Trial of 2-HOBA in Pulmonary Arterial Hypertension 2-HOBA - Pulmonary Arterial Hypertension	Phase 2	Not yet recruiting	Vanderbilt University Medical Center	12	2027-05-01	2026-11-10
No Time to Pause: Physical Activity to Improve Health of Midlife Hispanic Women Physical activity intervention - Elevated Blood Pressure, Perimenopause	Not applicable	Not yet recruiting	The University of Texas Medical Branch, Galveston	40	2027-04-20	2026-11-10
REmote Physical ACtivity Intervention for High Blood Pressure Postpartum Patient Portal Messaging, FitBit EHR Linkage - Hypertension (HTN), Hypertension ,Pregnancy	Not applicable	Not yet recruiting	Northwestern University	60	2027-04-01	2026-09-17
Monitoring Blood Pressure at Home and Pharmacy Telehealth Remote Blood Pressure Monitoring + Telehealth - Hypertension, Blood Pressure	Not applicable	Not yet recruiting	University of Alabama at Birmingham	420	2027-04-01	2026-06-15
Tracking Income Dynamics and Everyday Health Study Preventative health review invitation early in SNAP cycle, Financial counseling invitation early in the SNAP cycle, Aim 3 follow-up call early in the SNAP period - HIV, Hypertension	Not applicable	Not yet recruiting	University of Pennsylvania	400	2027-03-01	2026-10-19
An Open-Label Extension Study to Evaluate Inhaled Treprostinil SMI in Participants With Pulmonary Hypertension Associated With Chronic Obstructive Pulmonary Disease (PH-COPD) treprostinil SMI (treprostinil inhalation spray) - Pulmonary Hypertension Associated With Chronic Obstructive Pulmonary Disease	Phase 2 / Phase 3	Not yet recruiting	United Therapeutics	400	2027-03-01	2026-11-06
Evaluating the Effects of a Mindfulness Intervention on Health Outcomes in Individuals With Hypertension Mindfulness in Motion - Hypertension, Essential (Primary) Hypertension	Not applicable	Not yet recruiting	Ohio State University	140	2027-03-01	2026-11-12
Tailored Education for Aging and Cognitive Health: A Health Behavior Change Intervention for Midlife Adults at Risk for Alzheimer's Disease and Related Dementias TEACH, Basic health education - ADRD, Alzheimer's Disease	Not applicable	Not yet recruiting	Rhode Island Hospital	280	2027-02-15	2026-11-12
Monitoring Blood Pressure at Home and Pharmacy Telehealth Among People Living With HIV Remote Blood Pressure Monitoring + Telehealth - Hypertension, Blood Pressure Monitoring	Not applicable	Not yet recruiting	University of Alabama at Birmingham	572	2027-02-01	2026-09-30
Optimizing Care For Management Of Hard To Control Hypertension In Low-Income Patients Across Family Health Centers In New York City Multilevel Hypertension Care Model - Hypertension	Not applicable	Not yet recruiting	NYU Langone Health	628	2027-02-01	2026-07-14
Project HOPE (Hypertension Outreach Through Partnership and Engagement) Project HOPE Intervention - Hypertension (HTN)		Not yet recruiting	Johns Hopkins University	150	2027-02-01	2026-09-08

Showing 20 of 7523. Sign in to see all of them.

Narrower conditions

Hypertension, Pulmonary (1019)  ·  Diabetes Mellitus (774)  ·  Cardiovascular Diseases (721)  ·  Obesity (552)  ·  Essential Hypertension (469)  ·  Diabetes Mellitus, Type 2 (375)  ·  Dyslipidemias (282)  ·  Heart Diseases (282)  ·  Hypertension, Pregnancy-Induced (262)  ·  Heart Failure (253)  ·  Renal Insufficiency, Chronic (222)  ·  Hyperlipidemias (213)  ·  Motor Activity (211)  ·  Metabolic Syndrome (207)

Broader conditions

Vascular Diseases (7415)  ·  Cardiovascular Diseases (6802)  ·  Nutritional and Metabolic Diseases (1825)  ·  Pathological Conditions, Signs and Symptoms (1705)  ·  Metabolic Diseases (1603)  ·  Glucose Metabolism Disorders (1335)  ·  Respiratory Tract Diseases (1316)  ·  Endocrine System Diseases (1261)  ·  Lung Diseases (1145)  ·  Signs and Symptoms (914)  ·  Pathologic Processes (904)  ·  Urogenital Diseases (863)  ·  Female Urogenital Diseases and Pregnancy Complications (820)  ·  Nutrition Disorders (634)

Interventions

Amlodipine (343)  ·  Hydrochlorothiazide (244)  ·  Valsartan (180)  ·  Telmisartan (170)  ·  Losartan (123)  ·  Exercise (121)  ·  aliskiren (104)  ·  Nebivolol (66)  ·  Metoprolol (64)  ·  Olmesartan Medoxomil (64)  ·  Sildenafil Citrate (63)  ·  Chlorthalidone (61)  ·  Nifedipine (58)  ·  Irbesartan (55)  ·  candesartan cilexetil (54)

Sponsors

National Heart, Lung, and Blood Institute (NHLBI) (178)  ·  Novartis (147)  ·  Boehringer Ingelheim (124)  ·  Boryung Pharmaceutical Co., Ltd (80)  ·  Novartis Pharmaceuticals (77)  ·  Bayer (74)  ·  AstraZeneca (70)  ·  Chong Kun Dang Pharmaceutical (68)  ·  Brigham and Women's Hospital (67)  ·  University of Zurich (58)  ·  Johns Hopkins University (53)  ·  University of Pennsylvania (51)  ·  Duke University (49)  ·  University of Alabama at Birmingham (49)  ·  Takeda (46)

Countries

United States (2467)  ·  China (528)  ·  South Korea (448)  ·  Germany (426)  ·  Canada (382)  ·  United Kingdom (337)  ·  France (318)  ·  Italy (273)  ·  Spain (258)  ·  Brazil (250)  ·  Switzerland (203)  ·  Netherlands (197)  ·  Japan (190)  ·  Turkey (Türkiye) (186)  ·  Poland (167)

Top investigators

Silvia Ulrich, Prof. Dr. (17)  ·  Silvia Ulrich, Prof. (15)  ·  Horst Olschewski, MD (13)  ·  Italo Biaggioni, MD (11)  ·  Wanpen Vongpatanasin, MD (10)

Results publications

PMID 36398903, PMID 32905623, PMID 38682786, PMID 33769555, PMID 33089502, PMID 39526682, PMID 39356039, PMID 32748394, PMID 34164803, PMID 25771069, PMID 33027067, PMID 40013543, PMID 41264372, PMID 42370263, PMID 12493255, PMID 24107737, PMID 26243788, PMID 26354543, PMID 26589907, PMID 27162632, PMID 33107592, PMID 39171639, PMID 39498822, PMID 41903707, PMID 16982941, PMID 17238390, PMID 18806012, PMID 19249414, PMID 20175775, PMID 20573639, PMID 21093036, PMID 21740078, PMID 21869730, PMID 22230384, PMID 22608107, PMID 22880024, PMID 23636237, PMID 23661689, PMID 24210779, PMID 24578332, PMID 24916507, PMID 25527757, PMID 26187183, PMID 27206567, PMID 27263466, PMID 27659698, PMID 27888609, PMID 28859944, PMID 29030456, PMID 29098321

NIH funding

2009 (26), 2018 (26), 2008 (19), 2023 (16), 2025 (14), OT2HL158287 (9), 2016 (8), 2019 (8), 2014 (7), 2017 (7), P50MD017338 (6), R01HL132448 (5), U10HD021385 (5), U10HD027880 (5), U10HD034216 (5)