9 completed, 3 unknown, 2 active not recruiting, 2 terminated. 17 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 17 | Completed 9, Unknown 3, Active not recruiting 2, Terminated 2, Not yet recruiting 1 |
Follow Paroxysmal Atrial Fibrillation: new trials by email Literature Review of Paroxysmal Atrial Fibrillation trials Research Report on Paroxysmal Atrial Fibrillation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pragmatic Evaluation of a Pentaspline Pulsed Field Ablation System to Treat Atrial Fibrillation and Related Arrhythmias Farapulse Catheter System, Low-dose Colchicine - Persistent Atrial Fibrillation, Paroxysmal Atrial Fibrillation | Phase 4 | Active not recruiting | Vivek Reddy | 275 | 2025-04-15 | 2026-04-14 |
| Role of Eplerenone in Reducing Recurrence of Atrial Fibrillation in Patient With Structural Heart Disease Eplerenone - Paroxysmal Atrial Fibrillation | Phase 4 | Not yet recruiting | Assiut University | 100 | 2024-02-01 | 2023-12-13 |
| SINGLE SHOT CHAMPION PVI using the Arctic Front Cryoballoon (Medtronic), PVI using FARAPULSE Pulsed Field Ablation (Boston Scientific) - Paroxysmal Atrial Fibrillation | Phase 4 | Active not recruiting | Insel Gruppe AG, University Hospital Bern | 210 | 2022-09-26 | 2026-03-27 |
| Comparison of PolarX and the Arctic Front Cryoballoons for PVI in Patients With Symptomatic Paroxysmal AF PVI using the Arctic Front Cryoballoon (Medtronic), PVI using the PolarX Cryoballoon (Boston Scientific) - Paroxysmal Atrial Fibrillation | Phase 4 | Completed | Insel Gruppe AG, University Hospital Bern | 202 | 2021-03-29 | 2026-07-24 |
| Evaluation of VISITAG SURPOINT™ Module With External Processing Unit (EPU) Catheter ablation with EPU - Paroxysmal Atrial Fibrillation | Phase 4 | Completed | Biosense Webster, Inc. | 333 | 2018-09-04 | 2023-07-03 |
| Predictive Factors to Effectively Terminate Paroxysmal Atrial Fibrillation by Blocking Atrial Selective Ionic Currents Vernakalant, Flecainide - Paroxysmal Atrial Fibrillation | Phase 4 | Completed | David Filgueiras-Rama | 50 | 2017-01-01 | 2023-08-07 |
| Study of Statin for Reduction of Postoperative Paroxysmal Atrial Fibrillation rosuvastatin - Paroxysmal Atrial Fibrillation | Phase 4 | Unknown | The Third Xiangya Hospital of Central South University | 346 | 2015-08-01 | 2015-07-21 |
| Oral Anticoagulation Therapy Pilot Study Off OAT Group (Test), On OAT Group (Control) - Paroxysmal Atrial Fibrillation | Phase 4 | Terminated | Biosense Webster, Inc. | 80 | 2013-04-17 | 2025-02-04 |
| Antazoline in Rapid Cardioversion of Paroxysmal Atrial Fibrillation antazoline, 0.9% saline - Paroxysmal Atrial Fibrillation | Phase 4 | Completed | National Institute of Cardiology, Warsaw, Poland | 74 | 2012-11-01 | 2015-05-22 |
| Durability of Pulmonary Vein Isolation Following Cryoablation for Treatment of Paroxysmal Atrial Fibrillation Arctic Front Advance Cardiac CryoAblation system - Paroxysmal Atrial Fibrillation | Phase 4 | Completed | Medtronic Cardiac Rhythm and Heart Failure | 21 | 2012-08-01 | 2018-09-19 |
| Left Atrial Ablation of Paroxysmal Atrial Fibrillation With Implantable Loop Recorder Follow Up Study: The LAAPITUP 2 Study ILR insertion, AF ablation - Paroxysmal Atrial Fibrillation | Phase 4 | Unknown | Neil Sulke | 75 | 2012-04-01 | 2014-06-26 |
| Dronedarone in Pacemakers Patients With Paroxysmal Atrial Fibrillation Dronedarone, Placebo - Paroxysmal Atrial Fibrillation | Phase 4 | Unknown | Eastbourne General Hospital | 50 | 2010-03-01 | 2010-02-22 |
| ADenosine Following Pulmonary Vein Isolation to Target Dormant Conduction Elimination: the ADVICE Trial Additional ablation until elimination of dormant conduction, No additional ablation, Registry group - Paroxysmal Atrial Fibrillation, Pulmonary Vein Isolation | Phase 4 | Completed | Montreal Heart Institute | 550 | 2009-12-01 | 2014-04-03 |
| Post-Market Randomized Trial: Endoscopically- Guided Ablation vs. Radiofrequency Ablation Endoscopically guided PVI Ablation, RF PVI Ablation - Paroxysmal Atrial Fibrillation | Phase 4 | Terminated | CardioFocus | 21 | 2009-12-01 | 2016-08-01 |
| NAVISTAR® THERMOCOOL® Catheter Post Approval Registry Atrial fibrillation ablation - Paroxysmal Atrial Fibrillation | Phase 4 | Completed | Biosense Webster, Inc. | 437 | 2009-09-01 | 2025-02-04 |
| Ablation of the Pulmonary Veins for Paroxysmal Afib RF Ablation procedure - Paroxysmal Atrial Fibrillation | Phase 4 | Completed | Medtronic Cardiac Rhythm and Heart Failure | 55 | 2007-10-01 | 2018-09-19 |
| A Comparison of Antiarrhythmic Drug Therapy and Radio Frequency Catheter Ablation in Patients With Paroxysmal Atrial Fibrillation Radiofrequency ablation, antiarrhythmic drugs, Amiodarone, flecainide, propafenone, quinidine, dofetilide, sotalol, cibenzoline, beta blocking and calcium channel blocking agents and antiarrhythmic drugs, ThermoCool Radiofrequency Catheter - Paroxysmal Atrial Fibrillation | Phase 4 | Completed | Biosense Webster, Inc. | 112 | 2003-08-01 | 2025-02-28 |
Atrial Fibrillation (17)
Arrhythmias, Cardiac (17) · Cardiovascular Diseases (17) · Heart Diseases (17) · Pathologic Processes (17) · Pathological Conditions, Signs and Symptoms (17)
Flecainide (2) · Radiofrequency Ablation (2) · Amiodarone (1) · Antazoline (1) · Anti-Arrhythmia Agents (1) · Calcium Channel Blockers (1) · Catheter Ablation (1) · Colchicine (1) · Dronedarone (1) · Eplerenone (1) · Propafenone (1) · Quinidine (1) · Rosuvastatin Calcium (1) · Saline Solution (1) · Sotalol (1)
Biosense Webster, Inc. (4) · Insel Gruppe AG, University Hospital Bern (2) · Medtronic Cardiac Rhythm and Heart Failure (2) · Assiut University (1) · CardioFocus (1) · David Filgueiras-Rama (1) · Eastbourne General Hospital (1) · Montreal Heart Institute (1) · National Institute of Cardiology, Warsaw, Poland (1) · Neil Sulke (1) · The Third Xiangya Hospital of Central South University (1) · Vivek Reddy (1)
Switzerland (4) · United States (3) · Czechia (2) · France (2) · Germany (2) · United Kingdom (2) · Australia (1) · Austria (1) · Belgium (1) · Canada (1) · Denmark (1) · Italy (1) · Netherlands (1) · Poland (1) · Spain (1)
Pierre Jais, MD (2) · Tobias Reichlin, MD (2) · Vivek Reddy, MD (2) · A N Sulke, MD (1) · Aleksander Maciag, MD, PhD (1) · Andrea Natale, MD (1) · Antonio Raviele, MD (1) · Hanna Szwed, MD, PhD (1) · Karl Heinz Kuck, MD (1) · Laurent Macle, MD (1) · Michael Riley, MD (1) · Michal M Farkowski, MD (1) · Michel Haissaguerre, MD (1)
PMID 19029470, PMID 22217936, PMID 24097372, PMID 25644659, PMID 26211828, PMID 27516462, PMID 28339554, PMID 29092038, PMID 36137711, PMID 37722483, PMID 38752963, PMID 40162734