192 completed, 79 unknown, 33 recruiting, 24 not yet recruiting. 229 Not applicable, 33 Phase 4, 8 Phase 3, 5 Phase 2, 3 Early Phase 1.
Follow Anesthesia, General: new trials by email Literature Review of Anesthesia, General trials Research Report on Anesthesia, General
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Oral Dexmedetomidine in Pediatric MRI Dexmedetomidine, General Anesthesia (control group) - Anesthesia | Phase 1 | Not yet recruiting | Soroush Merchant | 18 | 2026-11-01 | 2026-08-04 |
| Epidural Versus General Anesthesia for Laparoscopic Hysterectomy epidural anesthesia, General Anesthesia (GA) - Anesthesia for Laparoscopic Hysterectomy | Not applicable | Not yet recruiting | Sabiha Başarı | 70 | 2026-10-22 | 2026-09-29 |
| Anaesthesia for Hip and Knee Arthroplasty (SPIGA) Spinal anaesthesia, General anaesthesia - Hip Arthroplasty, Knee Arthroplasty | Not applicable | Not yet recruiting | Zealand University Hospital | 3000 | 2026-10-01 | 2026-09-29 |
| Spinal Anesthesia Versus General Anesthesia Plus TAP Block for Laparoscopic Inguinal Hernia Repair General Anesthesia Plus Transversus Abdominis Plane Block, Spinal Anesthesia - Transversus Abdominis Plane Block (TAP Block), Laparoscopic Inguinal Hernia Repair | Not applicable | Recruiting | Fatma Cigdem Ozakin | 70 | 2026-09-01 | 2026-10-08 |
| Regional Nerve Block for Upper Extremity Surgery in Patients With Sarcopenia sarcopenia, Non-sarcopenia, General Anesthesia - Sarcopenia, Nerve Block | Not yet recruiting | Chang Gung Memorial Hospital | 150 | 2026-09-01 | 2026-08-11 | |
| Awareness Neuraxial Versus General Anesthesia in Frail Patients Undergoing Laparoscopic or Robotic Abdominopelvic Surgery. Neuraxial anesthesia, General Anesthesia, avoidance of GABAergic-drugs strategy - Fraily, Abdominal Surgery | Not applicable | Not yet recruiting | Ente Ospedaliero Ospedali Galliera | 100 | 2026-09-01 | 2026-03-20 |
| Effect of Anesthesia Type on Surgeon Workload During Endoscopic Kidney Stone Surgery General Anesthesia (GA), Spinal Anesthesia (SA) - Kidney Calculi | Not yet recruiting | Malatya Governor Research Hospital | 120 | 2026-09-01 | 2026-08-13 | |
| Cervical Erector Spinae Plane Block in Proximal Humeral Fracture Surgery, A Motor-Sparing Block Cervical erector spinae plane block, General anesthesia - Cervical, Erector Spinae Plane Block | Not applicable | Recruiting | Menoufia University | 44 | 2026-08-01 | 2026-09-17 |
| EFFECTS OF TWO ANESTHESİA TECHNİQUES ON INFLAMMATORY RESPONSE AND AMİNO ACİD METABOLİSM İN THYROİD SURGERY General Anesthesia, cervical plexus block - General Anesthesia, Cervical Plexus Block | Not applicable | Not yet recruiting | Harran University | 60 | 2026-07-30 | 2026-05-18 |
| Unilateral Spinal vs General Anaesthesia in Low EF Patients: A Hemodynamic Comparison Unilateral spinal anesthesia, General anesthesia - Hemodynamic (MAP) Stability | Enrolling by invitation | Sargodha Medical College | 78 | 2026-07-05 | 2026-08-10 | |
| Flex Appeal: Evaluating the Efficacy of Anesthetic Techniques for Manipulation of Knees Under Anesthesia Spinal Anesthesia, General Anesthesia, Propofol - Knee Stiffness After Total Knee Arthroplasty | Phase 4 | Recruiting | Duke University | 128 | 2026-06-01 | 2026-06-03 |
| Conscious Sedation Versus General Anesthesia for Pulsed Field Ablation in Paroxysmal Atrial Fibrillation Local Anesthesia With Conscious Sedation, General Anesthesia, VARIPULSE Pulsed Field Ablation System - Paroxysmal Atrial Fibrillation | Not applicable | Recruiting | China National Center for Cardiovascular Diseases | 390 | 2026-06-01 | 2026-10-16 |
| Comparative Study Between Spinal Anesthesia Versus General Anesthesia in Supine Percutaneous Nephrolithotomy Operation spinal anesthesia, General Anesthesia - Spinal Anesthesia, Percutaneous Nephrolithotomy | Not applicable | Not yet recruiting | Tanta University | 70 | 2026-05-30 | 2025-08-11 |
| Spinal Versus General Anesthesia in Open Simple Prostatectomy Spinal anesthesia, General anesthesia - Urologic Neoplasms, Benign Prostatic Hyperplasia | Not applicable | Recruiting | Hitit University | 80 | 2026-04-29 | 2026-06-16 |
| Anesthesia Technique and Outcomes in Mechanical Thrombectomy for Acute Ischemic Stroke General Anesthesia, Sedoanalgesia - Acute Ischemic Stroke | Completed | Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital | 481 | 2026-04-01 | 2026-04-08 | |
| General Anaesthesia vs Spinal Anaesthesia: Patient Outcomes and Success in Outpatient Primary Total Knee and Hip Arthroplasty General Anaesthesia, Spinal Anesthesia (bupivacaine) - Osteo Arthritis Knee and Hip, Osteo Arthritis | Phase 4 | Not yet recruiting | Region Örebro County | 600 | 2026-04-01 | 2026-01-12 |
| Safety and Efficacy of Conscious Sedation Versus General Anesthesia in Pulsed-Field Ablation for Paroxysmal Atrial Fibrillation conscious sedation, General Anesthesia (control group) - Atrial Fibrillation (Paroxysmal) | Not applicable | Not yet recruiting | Beijing Anzhen Hospital | 224 | 2026-04-01 | 2026-04-21 |
| Anesthesia Management in Endovascular Therapy for Ischemic Stroke - 2 General Anesthesia, Procedural sedation - Ischemic Stroke, Anterior Cerebral Circulation | Not applicable | Recruiting | University Hospital, Clermont-Ferrand | 958 | 2026-03-24 | 2026-09-02 |
| Total Intravenous Anesthesia vs Spinal Anesthesia in Patients Undergoing Unilateral Primary Total Knee Arthroplasty Total IntraVenous Anesthesia (TIVA), Spinal-Block, Electroencephalogram (EEG) - Total Knee Arthroplasty (TKA) | Phase 1 / Phase 2 | Recruiting | University of Chicago | 150 | 2026-03-11 | 2026-06-26 |
| Comparative Study Between Using Combined Propofol Sedation With subTenon's Infusion as Local Anaesthsia to the Eye Versus General Anesthesia for Strabismus Surgery in Adults sedation with subtenon injection of local anesthetic, General Anesthesia (control group) - Squint Anaesthesia | Not applicable | Not yet recruiting | Sohag University | 60 | 2026-03-10 | 2026-03-31 |
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Pain, Postoperative (39) · Agnosia (17) · Breast Neoplasms (11) · Postoperative Nausea and Vomiting (11) · Hip Fractures (10) · Postoperative Complications (10) · Pain (6) · Emergence Delirium (5) · Hernia, Inguinal (5) · Acute Pain (4) · Aortic Valve Stenosis (4) · Chronic Pain (4) · Delirium (4) · Ischemic Stroke (4) · Kidney Calculi (4)
Tanta University (10) · Cairo University (9) · Ain Shams University (6) · Makassed General Hospital (6) · RenJi Hospital (5) · Zagazig University (5) · Peking University First Hospital (4) · Seoul National University Hospital (4) · The Cleveland Clinic (4) · Alexandria University (3) · Ankara City Hospital Bilkent (3) · Antalya Training and Research Hospital (3) · Assiut University (3) · Beijing Tiantan Hospital (3) · Cliniques universitaires Saint-Luc- Université Catholique de Louvain (3)
China (54) · Egypt (52) · Turkey (Türkiye) (43) · United States (33) · France (16) · South Korea (12) · Canada (10) · Germany (10) · Belgium (7) · Italy (7) · Poland (7) · Sweden (7) · Switzerland (7) · Brazil (6) · Croatia (6)
Zoher Naja, MD (3) · Ali Sait Kavakli, MD (2) · Antonello Penna, MD, PhD (2) · Bozidar Duplancic (2) · Changhong Miao (2) · Daniel I Sessler, MD (2) · Giorgio Danelli, MD (2) · Haotian Lin, M.D., Ph.D (2) · Hee Young Kim, MD, PhD (2) · Hrvoje Vucemilovic (2) · Ivan Velat (2) · Ivo Juginovic (2) · Jin-Tae Kim (2) · Jonathan P Wanderer, MD, MPhil (2)
PMID 35857365, PMID 40772525, PMID 10485781, PMID 10740540, PMID 11049917, PMID 11753022, PMID 11942873, PMID 12414200, PMID 14576554, PMID 15690201, PMID 16846542, PMID 16943405, PMID 17258671, PMID 17885699, PMID 19468024, PMID 1989740, PMID 20236270, PMID 20395617, PMID 20445713, PMID 20512512, PMID 20803856, PMID 20947592, PMID 21641282, PMID 22110499, PMID 22237023, PMID 22710418, PMID 22713496, PMID 22791040, PMID 22855972, PMID 22989590, PMID 23345630, PMID 23392233, PMID 24238650, PMID 24370612, PMID 24455174, PMID 24821259, PMID 24968879, PMID 25009196, PMID 25009197, PMID 25261440, PMID 25480319, PMID 25822923, PMID 25948900, PMID 26083767, PMID 26284351, PMID 26424178, PMID 26507180, PMID 26588217, PMID 26930568, PMID 27401083
R01EY018184 (2), 2017 (1), R01DK032640 (1), R34HD060741 (1)