467 completed, 71 terminated, 42 active not recruiting, 37 unknown. 351 Not applicable, 45 Phase 4, 23 Phase 3, 10 Phase 2, 8 Phase 1.
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Validation Of anatomY-specific Aortic Valve Implantation Guided by Software Using EncantoR Prospective, single-arm, multi-center study. - Severe Native Calcific Aortic Stenosis, Symptomatic Heart Disease Due to Severe Native Calcific Aortic Stenosis | Not applicable | Not yet recruiting | Abbott Medical Devices | 150 | 2026-11-30 | 2026-07-10 |
| Belgo-Luxembourg Leadless PM Registry CT scan heart, 24 hour ambulatory ECG monitoring - Bradyarrhythmias, AV Block Complete | Not applicable | Not yet recruiting | Universitaire Ziekenhuizen KU Leuven | 190 | 2026-11-01 | 2026-10-19 |
| Merlin Expanded ECG NSR Left Bundle Branch Implant - Heart Failure, Bradycardia | Not yet recruiting | Abbott Medical Devices | 50 | 2026-10-05 | 2026-10-16 | |
| Evaluation of the DuoVT PFA System for Ventricular Tachycardia Ablation procedure with DuoVT PFA system - Ventricular Tachycardia | Not applicable | Recruiting | Abbott Medical Devices | 50 | 2026-09-29 | 2026-10-16 |
| A Post-Market Assessment of the Safety and Performance of the TriClip™ System Tricuspid Transcatheter Edge-to-Edge Repair (TEER) - Tricuspid Regurgitation (TR) | Recruiting | Abbott Medical Devices | 1000 | 2026-07-02 | 2026-10-06 | |
| Grid eXplore Mapping Study Grid X and EnSite X v3.1.1 Software - Paroxysmal Atrial Fibrillation (PAF) | Not applicable | Recruiting | Abbott Medical Devices | 200 | 2026-04-02 | 2026-07-01 |
| Comprehensive LEFt Atrial Appendage Occlusion With Rhythm Restoration PVI Ablation, Left Atrial Appendage Occluder Implant - Atrial Fibrillation (AF), Paroxysmal AF | Not applicable | Recruiting | Abbott Medical Devices | 240 | 2026-03-31 | 2026-07-13 |
| TriClip Japan Post-Approval Study The TriClip System - Tricuspid Regurgitation | Recruiting | Abbott Medical Devices | 250 | 2026-03-02 | 2026-04-03 | |
| Agilis RF TSP Early Feasibility Study Transseptal procedure with Agilis RF TSP System. - Cardiac Arrythmias, Left Atrial Appendage Closure | Not applicable | Recruiting | Abbott Medical Devices | 60 | 2026-02-16 | 2026-06-02 |
| A Clinical Evaluation of AMJ-401 AMJ-401 - Ischemic Heart Disease (IHD) | Not applicable | Active not recruiting | Abbott Medical Devices | 50 | 2025-12-17 | 2026-10-15 |
| LEAP 2 Chronic EFS AVEIR CSP Leadless Pacemaker System - Cardiac Pacemaker, Cardiac Rhythm Disorder | Not applicable | Recruiting | Abbott Medical Devices | 30 | 2025-12-13 | 2026-10-16 |
| BaLloon-based PFA Ablation poST Approval Outcomes for PAF and PersAF Pulsed Field Ablation - Paroxysmal AF, Atrial Arrhythmia | Not applicable | Active not recruiting | Abbott Medical Devices | 300 | 2025-12-11 | 2026-10-21 |
| Navitor Japan Study Navitor Transcatheter Aortic Valve Implantation - Severe Aortic Stenosis | Recruiting | Abbott Medical Devices | 100 | 2025-10-30 | 2026-05-26 | |
| Early Feasibility Study (EFS) of Abbott's Balloon-expandable (BE) TAVI System for the Treatment of Severe, Symptomatic Aortic Stenosis Abbott BE TAVI System - Symptomatic Severe Aortic Stenosis | Not applicable | Active not recruiting | Abbott Medical Devices | 11 | 2025-10-30 | 2026-02-06 |
| A Prospective Evaluation of Spinal Cord Induced Muscle Stimulation (MuscleSCS) for the Treatment of Chronic Low Back Pain MuscleSCS - Chronic Low Back Pain (CLBP) | Not applicable | Recruiting | Saint Francis Hospital | 30 | 2025-10-07 | 2025-10-10 |
| Peripheral Microvascular Resistance as a Predictor for Limb Salvage Peripheral vascular flow reserve measurement - Peripheral Arterial Disease | Not applicable | Withdrawn | Hackensack Meridian Health | 2025-09-15 | 2025-09-24 | |
| Abbott Cephea Mitral Valve Disease Registry Mitral Regurgitation, Mitral Stenosis | Recruiting | Abbott Medical Devices | 1000 | 2025-08-13 | 2026-09-10 | |
| Left Bundle Branch Area Pacing (LBBAP) PMCF Study LBBAP lead - Bradycardia, Right Ventricular Pacing | Not applicable | Recruiting | Abbott Medical Devices | 200 | 2025-07-24 | 2026-09-25 |
| TriClip CED RWE Study The TriClip System - Tricuspid Regurgitation | Recruiting | Abbott Medical Devices | 2200 | 2025-07-08 | 2025-08-11 | |
| Cephea South America Feasibility Study Cephea Mitral Valve System - Mitral Regurgitation, Mitral Stenosis | Not applicable | Active not recruiting | Abbott Medical Devices | 20 | 2025-06-17 | 2026-09-11 |
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Heart Failure (122) · Coronary Artery Disease (105) · Atrial Fibrillation (86) · Myocardial Ischemia (52) · Coronary Stenosis (47) · Coronary Restenosis (41) · Arrhythmias, Cardiac (40) · Coronary Disease (39) · Mitral Valve Insufficiency (32) · Bradycardia (30) · Cardiovascular Diseases (27) · Vascular Diseases (27) · Aortic Valve Stenosis (24) · Chronic Pain (21) · Heart Valve Diseases (20)
Catheter Ablation (11) · Defibrillators, Implantable (11) · Cardiac Resynchronization Therapy (9) · Transcatheter Aortic Valve Replacement (8) · Amiodarone (7) · Percutaneous Coronary Intervention (7) · Spinal Cord Stimulation (7) · Aspirin (4) · Deep Brain Stimulation (4) · Radiofrequency Ablation (4) · Stents (4) · Therapeutics (4) · Tomography, Optical Coherence (4) · Drug Delivery Systems (3) · Methods (3)
United States (319) · Germany (173) · Italy (122) · Netherlands (105) · France (97) · United Kingdom (96) · Spain (95) · Canada (94) · Australia (75) · Belgium (68) · Austria (49) · Switzerland (49) · Denmark (45) · Czechia (40) · Japan (37)
Nicole Harbert (10) · Kristin Ruffner, PhD (9) · Pooja Chatterjee (9) · Barathi Sethuraman (8) · Grant Kim (8) · Gregg W Stone, MD (7) · Ryan Palmer (5) · Ashish Oza (4) · Clay Cohorn (4) · Devyani Nanduri (4) · Dhanunjaya Lakkireddy, MD (4) · Kristin Ruffner (4) · Patrick Serruys, MD (4) · Sarah Kammer (4) · Carlo Gazzola, B. Sc. (3)
PMID 25940520, PMID 24746650, PMID 26825231, PMID 29089314, PMID 31561250, PMID 22017936, PMID 22115661, PMID 24412457, PMID 25244700, PMID 25593120, PMID 26139054, PMID 26585622, PMID 30586701, PMID 33031789, PMID 34794687, PMID 40223608, PMID 12957423, PMID 15474698, PMID 16139121, PMID 16261546, PMID 16504631, PMID 16750678, PMID 18814274, PMID 18992651, PMID 21232715, PMID 21232716, PMID 21422390, PMID 21492763, PMID 22814777, PMID 23633132, PMID 24750460, PMID 25011722, PMID 27412868, PMID 27932427, PMID 32558692, PMID 33893022, PMID 34525837, PMID 36074476, PMID 36404406, PMID 36456068, PMID 36951813, PMID 37612008, PMID 39581426, PMID 39855458, PMID 41133305, PMID 41903627, PMID 11420770, PMID 11603594, PMID 11899956, PMID 15464329
2008 (1), K23HL098370 (1), R01HL091069 (1), R01HL165840 (1), U01HL089709 (1), U01HL107407 (1), UL1TR000135 (1)