60 unknown, 48 completed, 4 recruiting, 3 terminated. 49 Not applicable, 27 Phase 2, 19 Phase 3, 9 Phase 4, 7 Phase 1.
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Apixaban VS Warfarin in AF Pts First Three Months After Repair or BIO AVR MVR Apixaban, Warfarin - Valve Disease, Heart, Atrial Fibrillation (AF) | Phase 3 | Not yet recruiting | Meshalkin Research Institute of Pathology of Circulation | 120 | 2026-02-01 | 2026-02-25 |
| Left Bundle Branch Pacing in Patients With Hypertrophic Cardiomyopathy After Myectomy ICD with left bundle branch area pacing (LBBAP), dual-chamber ICD - HCM - Hypertrophic Cardiomyopathy, Sudden Cardiac Death | Not applicable | Recruiting | Meshalkin Research Institute of Pathology of Circulation | 30 | 2025-11-14 | 2026-01-28 |
| Endocardial Vs Epicardial Ablation for Recurrent Paroxysmal AF Endocardial PVI, Epicardial Posterior Wall Isolation + LAA Exclusion + Endocardial PVI - Recurrent Paroxysmal Atrial Fibrillation Despite Prior Pulmonary Vein Isolation | Not applicable | Withdrawn | University of Rochester | 2025-01-01 | 2023-11-09 | |
| Cryoablation of Intercostal Nerves for Pain Management in Early Postoperative Period in Patients With Minimally Invasive Mitral Valve Surgery cryoablation of intercostal nerves - Mitral Regurgitation, Pain, Postoperative | Not applicable | Completed | Meshalkin Research Institute of Pathology of Circulation | 30 | 2024-03-10 | 2025-12-30 |
| Radiotherapy Exposed Lung Injury: Effect on Functioning - Cohort Radiation therapy protocol for Breast cancer, Spirography and assessment of pulmonary diffusion capacity, Cardiopulmonary stress test - Breast Neoplasms, Radiation Pneumonia | Recruiting | Meshalkin Research Institute of Pathology of Circulation | 200 | 2023-07-18 | 2025-02-11 | |
| Pulmonary Artery Denervation in Patients With Atrial Fibrillation and Group 2 of Pulmonary Hypertension Pulmonary vein isolation, Sham pulmonary artery denervation, Pulmonary artery denervation - Atrial Fibrillation, Pulmonary Hypertension | Not applicable | Unknown | Meshalkin Research Institute of Pathology of Circulation | 116 | 2023-05-22 | 2023-05-25 |
| Comparison of the Biomechanical Properties of the Wall of an Aneurysmal-altered Abdominal Aorta According to the Results of in Vivo Ultrasound and an Associated Study of Strength Characteristics in Vitro aneurysmectomy with sampling of a segment of the aneurysm wall - the Strength Properties of the Aorta in Vivo, the Strength Properties of the Aorta in Vitro | Unknown | Meshalkin Research Institute of Pathology of Circulation | 50 | 2023-01-01 | 2022-12-14 | |
| The Role of Artificial Intelligence in the Treatment of Abdominal Aortic Aneurysms prosthetics of the abdominal aorta, prosthetics of the abdominal aorta after determining the safe zones of clamping - Frequency of Embolic Complications, Frequency of Ischemic Complications | Not applicable | Unknown | Meshalkin Research Institute of Pathology of Circulation | 100 | 2023-01-01 | 2022-12-15 |
| Study of the No-touch Saphenous Vein Graft Сoronary bypass surgery according to the I-graft method, Сoronary bypass surgery by the method of free conduit - Coronary Artery Disease, Coronary Artery Stenosis | Not applicable | Unknown | Meshalkin Research Institute of Pathology of Circulation | 106 | 2022-12-22 | 2024-02-08 |
| A Study of Drug Coated Balloon For Treating the Side Branch in Complex Bifurcation Lesions Drug coated balloon for the side brunch, Conventional balloon for the side brunch - Coronary Artery Disease | Not applicable | Unknown | Meshalkin Research Institute of Pathology of Circulation | 80 | 2022-02-15 | 2022-02-03 |
| Carotid Revascularization With MicroNet Covered Stent Comparing Early Neurological Outcomes With Distal Versus Proximal EPS Emboshield NAV6™, Mo.Ma™ - Patients With Aterosclerotic Carotid Stenosis, Symptomatic Patients (Stenosis > 50%) | Not applicable | Recruiting | Meshalkin Research Institute of Pathology of Circulation | 366 | 2021-11-01 | 2022-02-25 |
| Esmolol for Myocardial Protection in Hypertrophic Obstructive Cardiomyopathy Esmolol, Placebo - Hypertrophic Obstructive Cardiomyopathy | Phase 4 | Unknown | Meshalkin Research Institute of Pathology of Circulation | 80 | 2021-10-06 | 2021-10-11 |
| Efficacy and Safety Comparison of the Endovascular and the Hybrid Methods for the Treatment of Prolonged Atherosclerotic Lesions of the Femoral-popliteal Segment Above the Knee, TASC II, Type D recanalization of the femoral-popliteal arterial segment above the knee with angioplasty and stenting with a biomimetic interwoven nitinol stent, supplemented by fasciotomy in Hunter's canal., recanalization of the femoral-popliteal arterial segment above the knee with angioplasty and stenting with a biomimetic interwoven nitinol stent. - Atherosclerosis, Ischemia Limb | Not applicable | Unknown | Meshalkin Research Institute of Pathology of Circulation | 100 | 2020-11-01 | 2020-10-19 |
| Efficacy and Safety Comparison of the Open Surgical and Endovascular Methods for the Treatment of Long Atherosclerotic Lesions of the Femoral-popliteal Segment Above the Knee, TASC II, Type D. Endovascular recanalization with angioplasty and stenting with the biomimetic interwoven nitinol stent, Femoropopliteal proximal bypass - Atherosclerosis, Ischemia Limb | Not applicable | Unknown | Meshalkin Research Institute of Pathology of Circulation | 110 | 2020-10-01 | 2020-10-19 |
| Efficacy and Safety Comparison of the Open and Endovascular Surgical Methods for the Treatment of Long Atherosclerotic Lesions of the Femoral-popliteal Segment Below the Knee, TASC D in Patients With Critical Limb Ischemia Endovascular recanalization, Open surgery - Atherosclerotic Ischemic Disease, Critical Limb Ischemia | Not applicable | Unknown | Meshalkin Research Institute of Pathology of Circulation | 90 | 2020-09-01 | 2020-10-12 |
| State of Oxygen Metabolism, Cardiovascular and Respiratory System Reserve Capacity in Patients Who Underwent COVID-19 Spirography and assessment of pulmonary diffusion capacity, Cardiopulmonary stress test, Computed tomography of the chest organs - Covid19, COVID19 Infection | Active not recruiting | Meshalkin Research Institute of Pathology of Circulation | 100 | 2020-08-25 | 2025-02-11 | |
| Full Metall Jacket Multilevel Segment Hybrid revascularization, Full metall Jacket - Superficial Femoral Artery Stenosis, Iliac Artery Occlusion | Not applicable | Unknown | Meshalkin Research Institute of Pathology of Circulation | 100 | 2020-06-30 | 2020-07-13 |
| a Randomized Clinical Trial Evaluating the Effectiveness of Carbon Dioxide Use in Cardiac Surgery carbon dioxide insufflation, No carbon dioxide insufflation - Carbon Dioxide | Not applicable | Unknown | Meshalkin Research Institute of Pathology of Circulation | 120 | 2020-06-19 | 2020-09-14 |
| SARS-CoV-2 Disguise Study SARS-CoV-2-test, SARS-CoV-2 questionnaire survey - Sars-CoV2 | Unknown | Meshalkin Research Institute of Pathology of Circulation | 900 | 2020-05-07 | 2020-05-20 | |
| Edge-to-edge Mitral Valve Repair in the Surgical Treatment for Hypertrophic Cardiomyopathy mitral valve repair by edge-to-edge technique, Septal myectomy - Hypertrophic Obstructive Cardiomyopathy | Not applicable | Unknown | Meshalkin Research Institute of Pathology of Circulation | 40 | 2020-03-12 | 2020-07-21 |
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Atrial Fibrillation (29) · Coronary Artery Disease (14) · Myocardial Ischemia (8) · Cardiomyopathy, Hypertrophic (6) · Hypertension (6) · Atherosclerosis (4) · Coronary Stenosis (4) · Myocardial Infarction (4) · Heart Defects, Congenital (3) · Mitral Valve Insufficiency (3) · Acute Kidney Injury (2) · Aortic Valve Insufficiency (2) · Arrhythmias, Cardiac (2) · Atrial Flutter (2) · Cardiovascular Diseases (2)
Radiofrequency Ablation (6) · Botulinum Toxins (5) · Saline Solution (5) · Warfarin (5) · Angioplasty (4) · Coronary Artery Bypass (4) · Mitral Valve Annuloplasty (4) · Stents (3) · Catheter Ablation (2) · Conversion to Open Surgery (2) · Exercise Test (2) · Metoprolol (2) · Propofol (2) · Sevoflurane (2) · Sodium Chloride (2)
Russia (115) · United States (9) · Bahrain (1) · Brazil (1) · China (1) · Greece (1) · Poland (1) · Saudi Arabia (1) · Slovenia (1)
Evgeny Pokushalov, MD, PhD (8) · Evgeny A Pokushalov, MD, PhD (6) · Andrey Karpenko (4) · Aleksandr V Bogachev-Prokophiev, PhD (3) · Vladimir V Lomivorotov, MD, PhD (3) · Alexander M. Chernyavskiy, MD PhD (2) · Alexander V. Bogachev-Prokophiev, MD, PhD (2) · Jonathan S. Steinberg, MD (2) · Oksana Kamenskaya, PhD, MD (2) · Vladimir Lomivorotov, MD, PhD (2) · Vladimir Lomivorotov, PhD (2) · Aleksandr V Bogachev-Prokophiev, MD PhD (1) · Alexander B Romanov, MD (1) · Alexander Cherniavskiy, MD, PhD (1) · Alexander V Bogachev-Prokophiev, PhD (1)
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