56 completed, 22 unknown, 11 recruiting, 10 terminated. 59 Not applicable, 12 Phase 4, 6 Phase 3, 2 Phase 2.
Follow Arrhythmia, Sinus: new trials by email Literature Review of Arrhythmia, Sinus trials Research Report on Arrhythmia, Sinus
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Predicting Severe Cardiac Arrhythmias in the Perioperative Period Using AI-ECG digital single-channel ECG recording - Atrial Fibrillation, Atrioventricular Block, Second and Third Degree | Not yet recruiting | I.M. Sechenov First Moscow State Medical University | 300 | 2026-12-31 | 2026-02-10 | |
| Belgo-Luxembourg Leadless PM Registry CT scan heart, 24 hour ambulatory ECG monitoring - Bradyarrhythmias, AV Block Complete | Not applicable | Not yet recruiting | Universitaire Ziekenhuizen KU Leuven | 190 | 2026-11-01 | 2026-10-19 |
| Procedural Endpoint in Left Bundle Branch Area Pacing: Conduction System Capture Versus LV Septal Capture LBBAP with mandatory left ventricular conduction system capture (LBBP or LFP), LBBAP with left ventricular septal capture as the accepted procedural endpoint (LVSP) - Bradycardia, Atrioventricular Block | Not applicable | Not yet recruiting | Yonsei University | 300 | 2026-10-01 | 2026-09-04 |
| Transjugular Approach for Implantation of Active Fixation Leadless Pacemakers Aveir VR Leadless Pacemaker - Bradycardia, Heart Block | Not applicable | Not yet recruiting | Min Shen | 15 | 2026-09-10 | 2026-09-03 |
| BIO|STREAM.CSP CLS Left bundle branch area pacing with Closed Loop Stimulation - Sinus Node Disease, Atrioventricular Block | Recruiting | Biotronik SE & Co. KG | 150 | 2026-05-29 | 2026-07-17 | |
| Safety, Performance, and Clinical Benefit of Pacing the Left Bundle Branch Area - Post-Market Clinical Follow-up Pacemaker lead - Bradycardia, Atrioventricular Block | Recruiting | Boston Scientific Corporation | 140 | 2025-12-19 | 2026-10-07 | |
| LEAP 2 Chronic EFS AVEIR CSP Leadless Pacemaker System - Cardiac Pacemaker, Cardiac Rhythm Disorder | Not applicable | Recruiting | Abbott Medical Devices | 30 | 2025-12-13 | 2026-10-16 |
| Prospective Cohort Study of Bachmann Bundle Versus Right Atrial Appendage Pacing: Impact on Atrial Cardiomyopathy Evaluated by Echocardiographic Parameters and Clinical Outcome Right Atrial Appendage Pacing, Bachmann Bundle Pacing - Sick Sinus Syndrome | Recruiting | Samsung Medical Center | 200 | 2025-12-09 | 2026-07-28 | |
| PACE-AF: Prospective Analysis of Cardiac Electrostimulation and Atrial Fibrillation Atrial Fibrillation, Sick Sinus Syndrome | Not yet recruiting | Ilya Lukin | 500 | 2025-12-01 | 2025-12-12 | |
| Left Bundle Branch Versus Minimized Ventricular Pacing in Patients With Sick Sinus Syndrome and Prolonged AV Interval LBBAP, MVP - Sick Sinus Syndrome, Atrioventricular Nodal Dysfunction | Not applicable | Recruiting | Asan Medical Center | 440 | 2025-05-02 | 2026-01-02 |
| Effect of Environment on the Central and Peripheral Nervous System Built environment, Natural environment - Rumination | Not applicable | Enrolling by invitation | University of South Florida | 95 | 2025-02-14 | 2025-03-25 |
| AVEIRâ„¢ Leadless Pacemaker Registry in Europe and MIddle East Region (PREMIER LEADLESS) Cardiac Pacing in Adherence With ESC Cardiac Pacing Guidelines | Not yet recruiting | King Fahad Armed Forces Hospital | 1698 | 2025-01-06 | 2025-01-17 | |
| BIOTRONIK Conduction System Pacing With the Solia Lead - Solia CSP S Solia CSP S lead - Sinus Node Dysfunction, Bradycardia | Not applicable | Completed | Biotronik, Inc. | 192 | 2024-12-18 | 2026-07-14 |
| Respiratory Sinus Arrhythmia (RSA) Pacing Post-CABG Surgery in Patients With HFrEF Atrial pacing with respiratory sinus arrhythmia (RSA) variability, Monotonic right atrial overdrive pacing - Heart Failure With Reduced Ejection Fraction | Not applicable | Completed | Ceryx Medical Ltd | 30 | 2024-11-22 | 2026-08-05 |
| Evaluating the Safety and Effectiveness of 5G Cloud Follow-up for Cardiovascular Implantable Electronic Devices Routine Management, 5G Cloud Follow-up - Sick Sinus Syndrome, Atrioventricular Block, Second and Third Degree | Not applicable | Recruiting | The Third People's Hospital of Chengdu | 688 | 2024-11-13 | 2024-11-21 |
| Respiratory Sinus Arrhythmia Pacing Post-CABG Surgery in Patients With HFrEF Atrial pacing with respiratory sinus arrhythmia (RSA) variability, Monotonic right atrial overdrive pacing - Heart Failure With Reduced Ejection Fraction | Not applicable | Recruiting | Ceryx Medical Australia | 54 | 2024-09-02 | 2025-07-22 |
| Comparison of Focal Cryoablation vs. Radiofrequency Cardioneuroablation for Bradyarrhythmias Focal Cryoablation, Radiofrequency Catheter Ablation - Bradycardia, Syncope, Vasovagal | Not applicable | Recruiting | Tomsk National Research Medical Center of the Russian Academy of Sciences | 60 | 2024-09-01 | 2026-06-26 |
| Cardioneuroablation for Bradyarrhythmia Ganglionated plexi ablation, Electrophysiological study - Bradycardia, Syncope | Not applicable | Recruiting | Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health | 106 | 2024-03-04 | 2024-03-05 |
| Beneficial or Fostering Future Struggles (B.F.F.s)? Characterizing the Role of Friends in the Development of 13- to 17-Year-Old Adolescents Debrief - Child Maltreatment, Interpersonal Relations | Not applicable | Unknown | University of South Carolina | 120 | 2023-12-02 | 2024-07-16 |
| Cardiac Denervation Ablation Strategy for Severe Sinus Bradycardia Sinus Bradycardia | Unknown | China National Center for Cardiovascular Diseases | 88 | 2023-09-13 | 2024-02-26 |
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Sick Sinus Syndrome (92) · Bradycardia (32) · Atrial Fibrillation (24) · Atrioventricular Block (23) · Heart Failure (16) · Arrhythmias, Cardiac (11) · Heart Block (11) · Syncope (6) · Ventricular Fibrillation (5) · Cardiovascular Diseases (4) · Heart Diseases (4) · Syncope, Vasovagal (4) · Tachycardia, Ventricular (4) · Ventricular Dysfunction (4)
Pathologic Processes (109) · Pathological Conditions, Signs and Symptoms (109) · Cardiovascular Diseases (105) · Heart Diseases (105) · Arrhythmias, Cardiac (98) · Cardiac Conduction System Disease (92) · Heart Block (81) · Nervous System Diseases (12) · Neurobehavioral Manifestations (10) · Neurologic Manifestations (10) · Signs and Symptoms (10) · Consciousness Disorders (9) · Unconsciousness (9) · Behavior (6)
Defibrillators (2) · Ivabradine (2) · Atenolol (1) · Bacitracin (1) · Blood Specimen Collection (1) · Built Environment (1) · Catheter Ablation (1) · Cephalexin (1) · Clindamycin (1) · Defibrillators, Implantable (1) · Device Lead Extraction (1) · Electrophysiologic Techniques, Cardiac (1) · Levofloxacin (1) · Losartan (1) · Nebivolol (1)
Abbott Medical Devices (11) · Medtronic Cardiac Rhythm and Heart Failure (7) · Boston Scientific Corporation (5) · Medtronic BRC (5) · Biotronik SE & Co. KG (4) · LivaNova (3) · Biotronik, Inc. (2) · China Medical University Hospital (2) · China National Center for Cardiovascular Diseases (2) · Guidant Corporation (2) · Tartu University Hospital (2) · Tongji Hospital (2) · Tulane University (2) · Aarhus University Hospital (1) · Aarhus University Hospital Skejby (1)
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Kwangdeok Lee (2) · Sarah A Gray, PhD (2) · Yan Wang, PhD (2) · Alessandro Capucci (1) · Andi Albertsen, MD (1) · Arun Rao, MD (1) · C Nimeth, MD (1) · Carlos Minguito Carazo, MD (1) · Carmine Muto, MD (1) · Charles Love, MD (1) · Chih-Chieh Yu, MD.PhD (1) · Chirag Barbhaiya, MD (1) · Chris van Groeningen, MD (1) · Christopher Ellis, M.D. (1)
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K23MH119047 (2), 2014 (1), IK2CX001874 (1), R00HD103958 (1), R21AT009470 (1), U01HL049804 (1)