13 completed, 9 unknown, 2 terminated, 1 active not recruiting. 11 Not applicable, 7 Phase 4, 5 Phase 3, 3 Phase 1, 2 Phase 2.
Follow this drug Literature Review of Propafenone trials Research Report on Propafenone
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dronedarone Rhythm Intervention for Early Atrial Fibrillation Dronedarone, flecainide, propafenone - Atrial Fibrillation (AF) | Phase 4 | Not yet recruiting | Inha University Hospital | 1898 | 2026-01-01 | 2025-12-22 |
| Pulsed Field Ablation (PFA) vs Anti-Arrhythmic Drug (AAD) Therapy as a First Line Treatment for Persistent Atrial Fibrillation FARAPULSE™ Pulsed Field Ablation (PFA) System, Anti-Arrhythmic Drug (AAD): Flecainide, Sotalol, Propafenone, Dofetilide, and Dronedarone - Persistent Atrial Fibrillation | Not applicable | Active not recruiting | Boston Scientific Corporation | 484 | 2023-12-28 | 2026-08-28 |
| Antazoline in Comparison to Propafenone in Pharmacological Cardioversion of Atrial Fibrillation. Antazoline, Propafenone - Atrial Fibrillation | Phase 4 | Unknown | Centre of Postgraduate Medical Education | 105 | 2019-09-01 | 2023-02-14 |
| Efficacy and Safety of Sotalol in Children With Arrhythmia sotalol, Propafenone, betaloc - Arrhythmia | Phase 4 | Unknown | Shengjing Hospital | 500 | 2019-08-01 | 2019-03-29 |
| Propafenone in the Treatment of Atrial Fibrillation Propafenone - Atrial Fibrillation | Not applicable | Completed | TSH Biopharm Corporation Limited | 71 | 2019-07-11 | 2021-09-23 |
| Bioequivalence Study of Two Formulations of Propafenone 300 mg Film-coated Tablets in Healthy Adult Volunteers After a Single Oral Dose Administration Under Fasting Conditions Propafenone, Rytmonorm - Bioequivalence | Phase 1 | Completed | Pharmtechnology LLC | 32 | 2019-03-23 | 2019-06-06 |
| Population Pharmacokinetics of Propafenone and Propranolol in Children Patients Propafenone and Propranolol - Arrhythmia | Unknown | Shandong University | 500 | 2019-02-01 | 2022-07-19 | |
| Early Aggressive Invasive Intervention for Atrial Fibrillation Cryoballoon-based PVI, Anti-Arrhythmic Drug Therapy - Atrial Fibrillation | Not applicable | Unknown | Jason Andrade | 303 | 2017-01-01 | 2022-10-10 |
| New Formulations of Propafenone to Treat Atrial Fibrillation (R)-propafenone, (S)-Propafenone, Placebo - Atrial Fibrillation | Phase 1 / Phase 2 | Terminated | Vanderbilt University | 193 | 2016-10-01 | 2022-06-03 |
| Comparison of Brain Perfusion in Rhythm Control and Rate Control of Persistent Atrial Fibrillation Propafenone, Apixaban - Persistent Atrial Fibrillation | Not applicable | Unknown | Yonsei University | 200 | 2015-11-01 | 2019-01-28 |
| Beta-blocker vs. Ic Antiarrhythmic Drug for PVC Propafenone, Indenol - Premature Ventricular Complex | Not applicable | Withdrawn | Yong Seog Oh | 2015-06-01 | 2024-04-23 | |
| Ablation Verses Anti-arrhythmic Therapy for Reducing All Hospital Episodes From Recurrent Atrial Fibrillation AVATAR-AF ablation, Anti-Arrhythmic therapy, Conventional AF ablation - Heart Failure, Recurrent Atrial Fibrillation | Not applicable | Completed | Imperial College London | 321 | 2015-05-01 | 2024-10-09 |
| A Prospective Study of Medical Therapy Against Cryoballoon Ablation in Symptomatic Recent Onset Persistent AF single ablation (CryoBalloonAblation (CBA), sequential drug adjustment (propafenone, sotalol or flecainide) - Atrial Fibrillation | Phase 4 | Completed | University Hospital, Ghent | 13 | 2015-03-03 | 2023-08-01 |
| Antiarrhythmic Drugs Assessment in Preventing Atrial Fibrillation Amiodarone, Propafenone, Sotalol - Atrial Fibrillation | Phase 4 | Unknown | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | 600 | 2014-05-01 | 2014-05-23 |
| Catheter Ablation Versus Antiarrhythmic Drugs for Outflow Tract Ventricular ARrhythmias antiarrhythmic drugs (Flecainide or Propafenone or Sotalol), Catheter Ablation - Ventricular Tachycardia, Ventricular Premature Complexes | Phase 4 | Unknown | Ospedale San Donato | 2013-01-01 | 2013-01-31 | |
| Efficacy of Pilsicainide After Radiofrequency Ablation of Paroxysmal Atrial Fibrillation pilsicainide, other class IC antiarrhythmic drug - Paroxysmal Atrial Fibrillation | Not applicable | Unknown | Korea University | 245 | 2012-07-01 | 2013-02-26 |
| Bioequivalence of RYTHMOL SR® Manufactured at Two Different Sites Propafenone - Arrhythmia, Cardiac | Phase 1 | Completed | GlaxoSmithKline | 38 | 2012-04-11 | 2017-06-12 |
| Efficacy of Propafenone Versus Dronedarone for the Maintenance of Sinus Rhythm in Patients With Atrial Fibrillation Propafenone, Dronedarone - Atrial Fibrillation | Not applicable | Completed | Samsung Medical Center | 98 | 2011-05-01 | 2013-11-25 |
| Catheter Ablation Compared With Pharmacological Therapy for Atrial Fibrillation (CAPTAF Trial) Catheterablation, Amiodarone, Sotalol - Atrial Fibrillation, Quality of Life | Not applicable | Unknown | Uppsala University Hospital | 152 | 2008-05-01 | 2017-05-09 |
| AV Node Ablation and Pacemaker Therapy Compared to Drug Therapy for Atrial Fibrillation - Pilot Study FDA approved rate and rhythm control drugs, AV Node ablation and device implant - Atrial Fibrillation, Heart Failure | Phase 3 | Terminated | Mayo Clinic | 27 | 2007-12-01 | 2013-04-04 |
Showing 20 of 28. Sign in to see all of them.
Atrial Fibrillation (22) · Arrhythmias, Cardiac (7) · Cardiovascular Diseases (3) · Heart Diseases (3) · Heart Failure (2) · Ventricular Premature Complexes (2) · Heart Arrest (1) · Myocardial Infarction (1) · Tachycardia, Ventricular (1) · Ventricular Fibrillation (1)
Biosense Webster, Inc. (1) · Boston Scientific Corporation (1) · Centre of Postgraduate Medical Education (1) · GlaxoSmithKline (1) · Imperial College London (1) · Inha University Hospital (1) · Jason Andrade (1) · Korea University (1) · Mayo Clinic (1) · Medtronic Cardiac Rhythm and Heart Failure (1) · Meshalkin Research Institute of Pathology of Circulation (1) · National Heart, Lung, and Blood Institute (NHLBI) (1) · Ospedale San Donato (1) · Pharmtechnology LLC (1) · ProRhythm, Inc. (1)
United States (8) · Canada (5) · South Korea (5) · China (3) · Italy (3) · Belgium (2) · France (2) · Taiwan (2) · Australia (1) · Austria (1) · Croatia (1) · Czechia (1) · Germany (1) · Hong Kong (1) · Poland (1)
H. Greene (2) · Ben Shoemaker, MD (1) · Bjorn Knollmann, MD/PhD (1) · Douglas L. Packer, MD (1) · Dr. Prapa Kanagaratnam (1) · Edward P. Gerstenfeld, MD (1) · Eric Sicard, MD (1) · Evgeny Pokushalov, MD, PhD (1) · Hugh Calkins, MD (1) · Jason Andrade, M.D. (1) · Luc Jordaens, MD, PhD (1) · Oussama Wazni, M.D. (1)
PMID 19029470, PMID 19738139, PMID 21076158, PMID 21422032, PMID 22032709, PMID 23500312, PMID 23748210, PMID 25134972, PMID 28974568, PMID 30342299, PMID 31152874, PMID 33197159, PMID 36166682, PMID 36342178, PMID 36576323, PMID 36800262, PMID 37018501, PMID 38007219, PMID 42041224, PMID 42774368
2008 (1), R01HL031472 (1), R01HL124935 (1)