20 completed, 8 not yet recruiting, 5 unknown, 4 recruiting. 45 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 45 | Completed 20, Not yet recruiting 8, Unknown 5, Recruiting 4, Terminated 3, Withdrawn 3, Active not recruiting 1, Enrolling by invitation 1 |
Follow Pain Management: new trials by email Literature Review of Pain Management trials Research Report on Pain Management
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Methadone Versus Standard of Care for Pain Control in Minimally Invasive Lung Resection Surgery Methadone, Standard of Care - Pain Management | Phase 4 | Not yet recruiting | Wake Forest University Health Sciences | 150 | 2026-12-01 | 2026-11-04 |
| Suzetrigine for Analgesiain Arthroscopic Rotator Cuff Repair Suzetrigine (Journavx), Matching placebo, Standard multimodal analgesia - Artroscopic Surgery, Pain Management | Phase 4 | Not yet recruiting | University of Alabama at Birmingham | 100 | 2026-11-01 | 2026-10-08 |
| The Effect of Bupivacaine Liposomes on Postoperative Pain in Lung Transplant Patients After Intercostal Nerve Block: a Randomized Controlled Study LB/BH intercostal nerve block, BH intercostal nerve block - Lung Transplantation, Pain Management | Phase 4 | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 88 | 2026-07-01 | 2026-06-11 |
| Clinical and Economic Evaluation of Point-of-care Ultrasound-guided Infiltration for Subacromial and Carpal Tunnel Syndromes in Primary Care: a Cluster-randomized Study Protocol. Standard Oral Treatment, Conventional Infiltration, Ultrasound-Guided Infiltration - Subacromial Impingement Syndrome, Carpal Tunnel Syndrome (CTS) | Phase 4 | Active not recruiting | Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina | 225 | 2026-06-01 | 2026-07-09 |
| Continous Infusion of Nefopam for Patients Undergoing Pancreatoduodenectomy Nefopam 120mg/day infusion, Lidocaine Infusion, Peridural - Pancreatoduodenectomy, Pain Management | Phase 4 | Recruiting | Iuliu Hatieganu University of Medicine and Pharmacy | 93 | 2026-03-01 | 2026-03-24 |
| ZYNRELEF vs Continuous Catheter for Pain Management Following Shoulder Arthroplasty Zynrelef, Bupivacaine - Total Shoulder Arthroplasty, Pain Management | Phase 4 | Enrolling by invitation | Washington University School of Medicine | 86 | 2026-02-14 | 2026-02-19 |
| Intrapleural Bupivacaine Analgesia for Postoperative Pain Management After Minimally Invasive Video-Assisted Thoracoscopic Surgery: A Randomized Controlled Trial Bupivacaine 0.125%, Bupivacaine 0.25%, Normal Saline - Pain Management | Phase 4 | Not yet recruiting | Shanghai Pulmonary Hospital, Shanghai, China | 249 | 2026-02-01 | 2026-02-06 |
| Efficacy of Methylprednisolone for Pain Control After ACL Repair Meloxicam 15 mg, Medrol 4 MG Oral Tablet Includes Medrol Dosepak, Gabapentin 300 mg - ACL Surgery, Pain Management | Phase 4 | Recruiting | St. Louis University | 90 | 2025-10-21 | 2025-10-24 |
| The Effect of Multimodal Pain Regimen on Use of Narcotics After Rotator Cuff Tear Repair Multimodal Pain Regimen, Standard of Care Pain Regimen - Rotator Cuff Repairs, Pain Management | Phase 4 | Recruiting | Montefiore Medical Center | 130 | 2025-07-21 | 2026-07-13 |
| Continuous vs. Bolus Administration of NSAIDs After Laparoscopic Surgery for Multimodal Analgesia Ibuprofen continuous infusion, Ibuprofen bolus injection - Analgesic Drugs, Analgesic, Nonopioid | Phase 4 | Recruiting | Federal Research and Clinical Centre of Intensive Care Medicine and Rehabilitology | 100 | 2025-05-05 | 2025-07-17 |
| Intravenous Acetaminophen to Reduce Post-operative Opioid Consumption IV Acetaminophen - Post Operative Analgesia, Opioid Consumption, Postoperative | Phase 4 | Not yet recruiting | Centre hospitalier de l'Université de Montréal (CHUM) | 140 | 2025-04-28 | 2025-04-11 |
| Reduced-pressure Pneumoperitoneum and Intraperitoneal Saline Washout to Alleviate Pain Following vNOTES Hysterectomy normal saline - Pain, Inflammatory, Pain Management | Phase 4 | Not yet recruiting | Erzincan Military Hospital | 94 | 2025-04-24 | 2025-04-25 |
| Preemptive Analgesia Of Dexmedetomidine Reduces Per-operation Pain Preemptive Dexmedetomidine injection, Sodium Chloride 0.9% Inj - Pain Management, Noncardiac Surgery | Phase 4 | Not yet recruiting | China International Neuroscience Institution | 208 | 2025-04-03 | 2025-04-09 |
| Perioperative Lidocaine Infusions for the Management of Pain From Burn Injury IV Lidocaine, IV Saline - Pain Management, Burn Injury | Phase 4 | Not yet recruiting | University of Washington | 20 | 2025-04-01 | 2025-04-04 |
| Effectiveness of Curcuminoids in Controlling Postoperative Pain Following Total Laparoscopic Hysterectomy liposomal curcumin - Postoperative Care, Pain Management | Phase 4 | Completed | Erzincan Military Hospital | 126 | 2025-03-21 | 2026-04-02 |
| Search to Advance Limited Use of Opioids Pilot: Optimization of Non-Opioid Therapy With a Steroid Dexamethasone 8mg, Placebo - Pain Management | Phase 4 | Terminated | Rutgers, The State University of New Jersey | 8 | 2023-11-27 | 2025-06-04 |
| ORAL AND INTRA - LIGAMENTARY PIROXICAM for Post Endodontic Pain Management intra-ligamentary - Pain Management, Post Endodontic Pain | Phase 4 | Completed | Pakistan Institute of Medical Sciences | 50 | 2023-05-27 | 2026-07-20 |
| Topical Lidocaine 23%/Tetracaine 7% Ointment for Post-Hemorrhoidectomy Analgesia: A Randomized Controlled Trial Lidocaine 23% / Tetracaine 7% topical ointment (compounded), Placebo ointment - Pain Management, Hemorrhoids Third Degree | Phase 4 | Completed | Pontificia Universidad Catolica de Chile | 74 | 2023-05-24 | 2026-07-07 |
| "Management of Low Back Pain in the Emergency Department With Different Analgesic Dosages" Ibuprofen 400 mg, Ibuprofen 800 mg - Low Back Pain, Mechanical, Ibuprofen | Phase 4 | Completed | Ankara City Hospital Bilkent | 144 | 2022-01-01 | 2023-10-03 |
| Multi-Modal Anesthesia Protocol in Pain Management of Patients Undergoing Posterior Lumbar Spinal Fusion Surgery Toradol, Morphine, Orphenadrine - Pain Management, Posterior Spinal Fusion | Phase 4 | Completed | University of Puerto Rico | 100 | 2021-04-05 | 2022-06-10 |
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Agnosia (45) · Pain (8) · Pain, Postoperative (4) · Acute Pain (2) · Cancer Pain (2) · Carpal Tunnel Syndrome (2) · Emergencies (2) · Burns (1) · Chronic Pain (1) · Femoral Fractures (1) · Hip Fractures (1) · Lacerations (1) · Low Back Pain (1) · Musculoskeletal Diseases (1) · Neoplasms (1)
Nervous System Diseases (45) · Neurobehavioral Manifestations (45) · Neurologic Manifestations (45) · Pathological Conditions, Signs and Symptoms (45) · Perceptual Disorders (45) · Signs and Symptoms (45) · Pain (10) · Pathologic Processes (6) · Wounds and Injuries (5) · Postoperative Complications (4) · Neuromuscular Diseases (3) · Peripheral Nervous System Diseases (3) · Cumulative Trauma Disorders (2) · Disease Attributes (2) · Fractures, Bone (2)
Acetaminophen (9) · Bupivacaine (8) · Morphine (5) · Gabapentin (4) · Ibuprofen (4) · Epinephrine (3) · Ropivacaine (3) · Sodium Chloride (3) · Dexamethasone (2) · Ethanol (2) · Hydrocodone (2) · Ketorolac (2) · Ketorolac Tromethamine (2) · Lidocaine (2) · Methylprednisolone (2)
University of Alabama at Birmingham (4) · Erzincan Military Hospital (2) · Pacira Pharmaceuticals, Inc (2) · The University of Hong Kong (2) · University of Washington (2) · Ankara City Hospital Bilkent (1) · Ataturk University (1) · Centre hospitalier de l'Université de Montréal (CHUM) (1) · China International Neuroscience Institution (1) · DeClaire LaMacchia Orthopaedic Institute (1) · Federal Research and Clinical Centre of Intensive Care Medicine and Rehabilitology (1) · Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina (1) · Hamad Medical Corporation (1) · Hartford Hospital (1) · Henry Ford Health System (1)
United States (14) · China (3) · Turkey (Türkiye) (3) · Canada (2) · France (2) · Hong Kong (2) · Belgium (1) · Chile (1) · Denmark (1) · Netherlands (1) · Pakistan (1) · Poland (1) · Puerto Rico (1) · Qatar (1) · Romania (1)
Ka Wing Ma, MBBS, MS (2) · Alexander Aleem, MD (1) · Ali Ahiskalioglu (1) · Anne-Marie Bollen, DDS, MS, PhD (1) · Anthony Morlandt, MD (1) · Brad Woodworth, MD (1) · Carlos Perez, MD (1) · Cecile Feldman, DMD, BMA (1) · Erin Partington Buczek, MD (1) · Ferdinand Chan, M.D. (1) · Franck Vandenbroucke-Menu, MD (1) · Hassan Danesi (1) · Holly B Ende, M.D, (1) · Ireana C Ng, MD (1)
PMID 1015603, PMID 11331167, PMID 11331334, PMID 11374619, PMID 11472277, PMID 12411815, PMID 12548273, PMID 12560416, PMID 14622770, PMID 14690106, PMID 17138203, PMID 17413915, PMID 18686750, PMID 18762870, PMID 19157368, PMID 19174373, PMID 19690943, PMID 22506940, PMID 23569691, PMID 23788067, PMID 23878064, PMID 25520223, PMID 2589650, PMID 26330019, PMID 26759680, PMID 27714758, PMID 27787895, PMID 28192892, PMID 28478185, PMID 31465115, PMID 32739962, PMID 33238043, PMID 34626927, PMID 34986477, PMID 36522767, PMID 37192425, PMID 37218951, PMID 38640500, PMID 41733913, PMID 42207991, PMID 9862240
2016 (1), 2025 (1)