473 completed, 90 recruiting, 76 unknown, 34 not yet recruiting. 426 Not applicable, 93 Phase 1, 87 Phase 2, 55 Phase 3, 52 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Hybrid Type 1 Trial of a Parent-Based Intervention Addressing Social Media and Adolescent Alcohol Use Combined Alcohol and Social Media PBI and PFI, Alcohol and Social Media PBI, Power of Parents - Adolescent Alcohol Use | Not applicable | Not yet recruiting | The University of Texas at Arlington | 900 | 2027-07-01 | 2026-06-24 |
| A Feasibility and Acceptability Study of a Large Language Model-based Chatbot for Brief Alcohol Intervention Among Emerging Adults Large language model-based chatbot brief alcohol intervention session - Alcohol Use Disorder | Not applicable | Not yet recruiting | Massachusetts General Hospital | 20 | 2027-06-01 | 2025-10-22 |
| Integrated Digital Health Approach to Reduce Hazardous Alcohol Use and Chronic Pain Among Rural Populations Mobile Intervention for Alcohol and Pain, Control Intervention - Chronic Pain, Unhealthy Alcohol Use | Not applicable | Not yet recruiting | Boston University Charles River Campus | 260 | 2027-02-01 | 2026-09-04 |
| Effects of Ketones on Brain Energetics and Alcohol Consumption in Alcohol Use Disorder Kenetik, magnetic resonance imaging scan, Alcohol bar lab - Alcohol Use Disorder, Ketosis | Phase 2 / Phase 3 | Recruiting | University of Pennsylvania | 60 | 2026-12-01 | 2026-10-21 |
| Examining the Role of Sensitivity to Uncertain Threat and Alcohol Response in Risk for Alcohol Use Disorder Following Sexual Assault in College Women Alcohol, Placebo - Sexual Assault, Alcohol Intoxication | Early Phase 1 | Not yet recruiting | Ohio State University | 220 | 2026-12-01 | 2026-10-26 |
| ALDH2 Genetic Testing in East Asian Community Genetic Test Results Return, Alcohol Flushing Education - Healthy Adult, Flushing | Not applicable | Not yet recruiting | Northwestern University | 100 | 2026-11-01 | 2026-08-11 |
| Eye-Tracking Alcohol Warning Alcohol Cancer Warning Labels - Alcohol | Not applicable | Not yet recruiting | University of Miami | 50 | 2026-11-01 | 2026-10-20 |
| Pain Sensitivity, Alcohol-Induced Analgesia, and Heavy Drinking in Individuals With Opioid Use Disorder Alcohol, Placebo - Opioid Use Disorder, Alcohol Intoxication | Early Phase 1 | Not yet recruiting | Ohio State University | 90 | 2026-11-01 | 2026-10-26 |
| Alcohol Neurolysis and Capsaicin for Postamputation Pain (PAP) Injection of alcohol near neuroma, Lidocaine 2% injection, Injection of capsaicin 150 mcg per mL if relief with lidocaine 2% - Postamputation Pain | Not applicable | Not yet recruiting | Northwestern University | 120 | 2026-10-31 | 2026-08-18 |
| Environment and Alcohol: A Pilot Study Evaluate the effects of Environmental Enrichment (EE) on alcohol consumption - Alcohol Use Disorder | Phase 1 | Recruiting | National Institute on Drug Abuse (NIDA) | 44 | 2026-10-29 | 2026-10-26 |
| Biomarker Feedback Intervention eCHECKUP TO GO (eCTG), eCHECKUPTOGO + brief personalized alcohol biomarker feedback intervention (eCTG + TAC) - High Risk Drinking, College Student Drinking | Not applicable | Not yet recruiting | Penn State University | 150 | 2026-10-15 | 2026-07-08 |
| Effectiveness Trial of an mHealth Intervention to Help Parents Prevent Early Onset Alcohol Use BIPAS Alcohol - Alcohol Misuse, Alcohol Prevention | Phase 3 | Not yet recruiting | RTI International | 4000 | 2026-10-15 | 2026-10-05 |
| Alcohol Sensitivity Among Older Adults Who Consume Alcohol Alcohol (Oral), Placebo Control - Healthy Adult Participants | Not applicable | Recruiting | University of Florida | 80 | 2026-10-03 | 2026-09-30 |
| Brief Alcohol Treatment for Women Veterans in Primary Care Brief, Integrated Intervention for Women Veterans with Unhealthy Alcohol Use in Primary Care, Primary care usual care - Alcohol Misuse | Not applicable | Not yet recruiting | Syracuse VA Medical Center | 70 | 2026-10-01 | 2026-02-17 |
| Periodontal Disease and Small Vulnerable Newborns in Rural Nepal: A Community-based Trial A package of oral health interventions, including a daily antiseptic oral rinse (alcohol-free cetylpyridinium chloride (0.075%)) - Preterm Birth, Low Birth Weight | Phase 3 | Not yet recruiting | Johns Hopkins Bloomberg School of Public Health | 2280 | 2026-10-01 | 2026-07-09 |
| Reducing Cardiovascular Risks: The Role of Alcohol Use Alcohol Abstinence, Control arm - Alcohol Drinking, Drinking Behavior | Not applicable | Recruiting | The University of Texas at Arlington | 148 | 2026-10-01 | 2026-10-06 |
| Sensory and Physical Reactions to Beverage Cues Alcohol Cue Reactivity Paradigm - Alcohol Use Disorder (AUD) | Not applicable | Recruiting | University of Texas Southwestern Medical Center | 20 | 2026-10-01 | 2026-08-26 |
| Renal Artery Denervation Assessment Without Antihypertensive Medication Regimen (RADAR) Dehydrated Alcohol Injection, USP, Sham procedure - Hypertension, Hypertension,Essential | Phase 3 | Not yet recruiting | Ablative Solutions, Inc. | 202 | 2026-10-01 | 2026-08-20 |
| Oral Hygiene Assistance Training Program Stannous Fluoride Toothpaste (SnF), sodium fluoride 5000 ppm, cetylpyridinium chloride (0.075%) and zinc alcohol free mouthwash - Elderly, Periodontal Disease | Phase 4 | Not yet recruiting | Colgate Palmolive | 500 | 2026-09-20 | 2026-09-08 |
| The PSP Alcohol Reset Course Self-Guided PSP Alcohol Reset Course - Alcohol Misuse | Not applicable | Recruiting | University of Regina | 60 | 2026-09-17 | 2026-10-14 |
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Alcohol Drinking (158) · Alcoholism (143) · Alcoholic Intoxication (29) · Substance-Related Disorders (29) · Binge Drinking (23) · Alcohol-Related Disorders (16) · Drinking Behavior (14) · Surgical Wound Infection (14) · Infections (13) · Marijuana Abuse (12) · Alcohol Drinking in College (11) · COVID-19 (11) · Diabetes Mellitus, Type 2 (11) · Hypertension (11) · Pain (11)
Centre for Addiction and Mental Health (15) · University of Washington (13) · Yale University (13) · University of California, San Francisco (12) · Brown University (11) · VA Office of Research and Development (11) · Johns Hopkins University (9) · The University of Hong Kong (9) · University of Pennsylvania (9) · National Institute on Alcohol Abuse and Alcoholism (NIAAA) (8) · Parc de Salut Mar (8) · University of North Carolina, Chapel Hill (8) · Johnson & Johnson Consumer Inc. (J&JCI) (7) · Karolinska Institutet (7) · University of Chicago (7)
United States (410) · Canada (28) · Spain (27) · France (25) · Netherlands (19) · Egypt (17) · Germany (16) · Denmark (14) · Brazil (11) · United Kingdom (11) · Hong Kong (10) · Sweden (10) · China (9) · Australia (6) · Turkey (Türkiye) (6)
Jeffery Milleman, DDS (6) · Bernard Le Foll, MD, PhD (4) · Elizabeth Lippard, PhD (4) · Henk FJ Hendriks, PhD (4) · Vijay A Ramchandani, Ph.D. (4) · Carolyn Lauckner, PhD (3) · Corinde Wiers, Ph.D. (3) · Heather Hadjistavropoulos, PhD (3) · Michael A Cucciare, PhD (3) · Alison Breland, PhD (2) · Amparo Garcia-Tejedor, MDPhD (2) · Anne H Berman, PhD (2) · Annette Binder, Dr. med. (2) · Ansel T Hillmer, Ph.D. (2)
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R01AA022222 (3), K01AA031524 (2), P01AA029540 (2), R01DA008391 (2), R01DA052295 (2), R21AA031088 (2), 1DP5OD019809 (1), 1IK2RX003520-01A2 (1), 2015 (1), 2016 (1), 2019 (1), D43TW009763 (1), F31AA026195 (1), F31AA026486 (1), F31AA028751 (1)