Burns: Clinical Trials

391 completed, 129 unknown, 80 terminated, 64 withdrawn. 399 Not applicable, 107 Phase 2, 73 Phase 3, 53 Phase 1, 51 Phase 4.

By phase and status

Phase	Trials	Status
Not applicable	399	Completed 200, Unknown 72, Terminated 30, Not yet recruiting 29, Withdrawn 24, Recruiting 22, Active not recruiting 11, Enrolling by invitation 10, Suspended 1
Phase 2	107	Completed 48, Terminated 21, Unknown 14, Recruiting 9, Withdrawn 9, Active not recruiting 3, Not yet recruiting 2, Suspended 1
Phase 3	73	Completed 32, Unknown 11, Terminated 10, Withdrawn 10, Recruiting 6, Active not recruiting 3, Not yet recruiting 1
Phase 1	53	Completed 23, Unknown 10, Terminated 7, Recruiting 5, Withdrawn 3, Active not recruiting 2, Not yet recruiting 2, Suspended 1
Phase 4	51	Completed 21, Terminated 9, Unknown 7, Recruiting 6, Withdrawn 5, Not yet recruiting 2, Enrolling by invitation 1
Early Phase 1	9	Completed 3, Unknown 2, Not yet recruiting 1, Recruiting 1, Terminated 1, Withdrawn 1

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Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Magnesium Sulfate in Pediatric Burn Dressing Changes magnesium sulfate, Normal Saline (0.9% NaCl) - Pediatric Burns	Phase 1	Not yet recruiting	Hennepin Healthcare Research Institute	10	2027-12-01	2026-10-09
VR-PAT and fNIRS to Identify CNS Biomarkers of Pain VR-PAT - Acute Pain, Pediatric ALL	Not applicable	Not yet recruiting	Nationwide Children's Hospital	4	2027-07-01	2026-09-09
Video-Guided Jaw Relaxation and Breathing Exercises in Children With Burns Video-Guided Jaw Relaxation, Video-Guided Breathing Exercise - Burn	Not applicable	Not yet recruiting	Izmir Katip Celebi University	60	2027-06-01	2026-09-08
Post-Operative Use of FS2 to Mitigate Scarring in Burn Patients IP1 control cream (Vehicle base), IP2 - 0.5% w/w FS2 - Burn Scar, Burn Wound	Phase 2 / Phase 3	Recruiting	Birch BioMed Inc	70	2027-03-01	2026-09-30
Randomized Trial of a Sun Safety Intervention for Young Adults Healthy Skin, Healthy Lifestyle - Sunburn	Not applicable	Not yet recruiting	University of Connecticut	278	2027-02-01	2026-09-11
Neurobiology of Pain in Burn Survivors Cognitive Behavioral Therapy, Pain Education - Burn, Chronic Pain	Not applicable	Not yet recruiting	Spaulding Rehabilitation Hospital	92	2027-01-01	2026-09-22
Tools for Return of Facial Function Intraoral Stretching Splints - Facial Scarring, Facial Trauma	Not applicable	Not yet recruiting	The University of Texas Medical Branch, Galveston	50	2026-12-01	2026-09-17
Comparison of Topical Antibiotics Versus Systemic Antibiotics in Preventing Burn Wound Infection in Pediatric Burn Patients Silver Sulfadiazine Cream 1%, Amoxicillin and clavulanate - Burn	Not applicable	Not yet recruiting	abdul mateen	222	2026-11-05	2026-10-13
Sepsis Biomarker Monitoring in Burn Patients PSP Monitoring - Sepsis, Burn	Not applicable	Not yet recruiting	Texas Tech University Health Sciences Center	120	2026-11-01	2026-10-08
Impact of Range of Motion Exercises on Pain and Functional Ability Range of Motion exercises - Impact of ROM Exercises on Pain and Functional Ability in Patients With Second -Degree Burns	Not applicable	Not yet recruiting	Al-Azhar University	80	2026-11-01	2026-10-20
Efferon LPS Hemoadsorption in in Patients With Thermal Burns Efferon LPS - Burns	Not applicable	Recruiting	Efferon JSC	50	2026-10-21	2026-10-23
Impact of Inspiratory Muscle Training Post-Burn Inspiratory muscle training, Conventional physical therapy - Burn	Not applicable	Recruiting	Cairo University	60	2026-10-08	2026-10-14
Deepview HHF Training and Validation Study DeepView AI System - Burns, Burn Injury		Not yet recruiting	SpectralMD	280	2026-10-05	2026-10-07
Effect of Paraffin Wax on Joint Contractures Paraffin wax, Mineral oil - Burn Joints, Joint Contractures	Not applicable	Not yet recruiting	Centre hospitalier de l'Université de Montréal (CHUM)	12	2026-10-01	2026-09-28
Evaluation of Safety and Efficacy of Dehydrated Human Amnion-Intermediate-Chorion Membrane (dHAICM) Allograft in Treatment of Partial Thickness Thermal Burns Amnion-Intermediate-Chorion, Standard of Care (SOC) - Partial Thickness Burn	Phase 4	Withdrawn	Cellution Biologics		2026-10-01	2026-08-27
Response of Muscle Mechanical Properties to Early Multi-angles Isometric Exercises in Acute Burn Patients isometric exercise program, conventional physical therapy - Burns	Not applicable	Not yet recruiting	Cairo University	40	2026-10-01	2026-09-22
BURN-ASV Trial: Adaptive Support Ventilation in Severe Burn Injury Adaptive Support Ventilation (ASV), Conventional Lung-Protective Mechanical Ventilation - Burn, Mechanical Ventilation	Not applicable	Not yet recruiting	Ukrainian Society of Regional Anesthesia and Pain Therapy	100	2026-09-23	2026-06-29
ASV and Targeted Fluid Resuscitation in Severe Burns Burn, War-Related Injuries		Not yet recruiting	Ukrainian Society of Regional Anesthesia and Pain Therapy	100	2026-09-23	2026-07-08
Nurse Led Aromatherapy Aromatherapy - Burns and Scalds	Not applicable	Not yet recruiting	KK Women's and Children's Hospital	100	2026-09-01	2026-08-19
Patients´ Experiences of Calorimetry Measurements Experiences, Burn		Not yet recruiting	Uppsala University Hospital	20	2026-09-01	2026-09-24

Showing 20 of 808. Sign in to see all of them.

Narrower conditions

Wounds and Injuries (62)  ·  Pain (53)  ·  Cicatrix (31)  ·  Sunburn (29)  ·  Anxiety Disorders (25)  ·  Cicatrix, Hypertrophic (17)  ·  Critical Illness (16)  ·  Agnosia (14)  ·  Pressure Ulcer (14)  ·  Sepsis (14)  ·  Acute Pain (13)  ·  Infections (13)  ·  Inflammation (13)  ·  Smoke Inhalation Injury (12)

Broader conditions

Wounds and Injuries (746)  ·  Pathological Conditions, Signs and Symptoms (250)  ·  Pathologic Processes (140)  ·  Signs and Symptoms (125)  ·  Neurologic Manifestations (94)  ·  Skin and Connective Tissue Diseases (72)  ·  Skin Diseases (66)  ·  Nervous System Diseases (55)  ·  Fibrosis (46)  ·  Mental Disorders (40)  ·  Infections (35)  ·  Cardiovascular Diseases (32)  ·  Photosensitivity Disorders (29)  ·  Vascular Diseases (28)

Interventions

Standard of Care (21)  ·  Exercise (9)  ·  Silver Sulfadiazine (9)  ·  Sodium Chloride (9)  ·  Propranolol (8)  ·  Saline Solution (8)  ·  Bacitracin (6)  ·  Blood Specimen Collection (6)  ·  Control Groups (6)  ·  Extracorporeal Shockwave Therapy (6)  ·  Albumins (5)  ·  Resistance Training (5)  ·  Ringer's Lactate (5)  ·  Skin Transplantation (5)  ·  Sugars (5)

Sponsors

The University of Texas Medical Branch, Galveston (31)  ·  Cairo University (28)  ·  Massachusetts General Hospital (22)  ·  Hangang Sacred Heart Hospital (17)  ·  Shriners Hospitals for Children (17)  ·  United States Army Institute of Surgical Research (17)  ·  Qassim University (10)  ·  University of Texas Southwestern Medical Center (10)  ·  American Burn Association (8)  ·  Association of Dutch Burn Centres (8)  ·  The Metis Foundation (8)  ·  Avita Medical (7)  ·  Centre hospitalier de l'Université de Montréal (CHUM) (7)  ·  Hacettepe University (7)  ·  National Institute of General Medical Sciences (NIGMS) (7)

Countries

United States (313)  ·  Egypt (53)  ·  Turkey (Türkiye) (41)  ·  Canada (38)  ·  France (28)  ·  Germany (25)  ·  South Korea (23)  ·  Brazil (18)  ·  China (18)  ·  Netherlands (17)  ·  Switzerland (16)  ·  United Kingdom (16)  ·  Italy (15)  ·  Belgium (13)  ·  Israel (10)

Top investigators

David N Herndon, MD (15)  ·  David R. Patterson, Ph.D. (5)  ·  Marc G Jeschke, MD PhD (5)  ·  Ronald G Tompkins, MD, ScD (5)  ·  Ronald G. Tompkins, MD, ScD (5)  ·  Tobias Kisch, MD (5)  ·  Henry Xiang, MD, MPH, PhD (4)  ·  Rodney Chan, MD (4)  ·  Steven E Wolf, MD (4)  ·  Cheong Hoon Seo, M.D. (3)  ·  David Herndon, MD (3)  ·  Kevin Foster, MD (3)  ·  Maged Basha, PhD (3)  ·  Michael Albrecht, MD (3)

Results publications

PMID 21789167, PMID 39115183, PMID 11680441, PMID 17245174, PMID 18375483, PMID 18791359, PMID 20802500, PMID 22110166, PMID 22606232, PMID 23401516, PMID 24137663, PMID 27433905, PMID 31475319, PMID 31864784, PMID 33316436, PMID 34554139, PMID 38837237, PMID 39089770, PMID 40407357, PMID 1002644, PMID 1003586, PMID 10329105, PMID 1052771, PMID 10793162, PMID 10923010, PMID 11344264, PMID 11509512, PMID 11525858, PMID 11537577, PMID 11576045, PMID 11734620, PMID 11753055, PMID 11855913, PMID 12091180, PMID 12598483, PMID 12694482, PMID 12714344, PMID 12794413, PMID 12890465, PMID 12914662, PMID 13105270, PMID 13126521, PMID 13571547, PMID 1361207, PMID 13934413, PMID 1402772, PMID 14209177, PMID 15060765, PMID 15062754, PMID 15103422

NIH funding

P50GM021700 (5), P50GM060338 (2), R01GM042725 (2), U54GM062119 (2), 2018 (1), D43TW009345 (1), K23AT011389 (1), K23DA052041 (1), K23HD098328 (1), K23MH141296 (1), P01NS119159 (1), R01CA309495 (1), R01GM056687 (1), R01GM068865 (1), R01GM108634 (1)