77 completed, 21 unknown, 10 terminated, 8 recruiting. 122 Phase 3, 15 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 122 | Completed 77, Unknown 21, Terminated 10, Recruiting 8, Withdrawn 4, Not yet recruiting 2 |
| Phase 2 | 15 | Completed 9, Recruiting 2, Terminated 2, Unknown 1, Withdrawn 1 |
Follow Neuralgia: new trials by email Literature Review of Neuralgia trials Research Report on Neuralgia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Corticosteroid Lumbar Epidural Analgesia for Radicular Pain 2 SP-102, Placebo, Dexamethasone Sodium Phosphate 10 MG/ML - Lumbosacral Radicular Pain | Phase 3 | Not yet recruiting | Semnur Pharmaceuticals, Inc. | 755 | 2027-02-01 | 2026-09-09 |
| Extended-release Pregabalin for the Treatment of Neuropathic Pain in Patients With Diabetic Peripheral Neuropathy and Postherpetic Neuralgia Experimental: Pregabalin XR, Comparator: Dorene Tabs, Comparator placebo - Diabetic Neuropathy, Neuropathic Pain | Phase 3 | Recruiting | Brainfarma Industria Química e Farmacêutica S/A | 348 | 2026-06-18 | 2026-07-20 |
| Cervical Facet Injection of Corticosteroids for the Management of Cervicobrachialgia Dexamethasone, Isotonic saline solution - Cervicobrachial Neuralgia | Phase 3 | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 70 | 2026-01-01 | 2025-08-12 |
| Non-Invasive Pulsed Radiofrequency for the Treatment of Neuropathic Pain Active Treatment, Non-active Treatment - Pain, Nerve | Phase 2 / Phase 3 | Recruiting | Stanford University | 95 | 2024-11-01 | 2026-04-24 |
| Analgesic Effectiveness of Capsaicin 8% Cutaneous Patch in Children Capsaicin 8% patch, Hydrocolloid dressing - Neuropathic Pain, Chronic Pain | Phase 3 | Recruiting | University Hospital, Brest | 46 | 2024-03-05 | 2026-06-15 |
| Evaluation of the Efficacy of Therapeutic Infiltrations of the Pudendal Nerve, Performed Under Neurostimulation on Pain, 1 Month After an Infiltration of Local Anaesthetic, in the Treatment of Pudendal Neuralgia. Lidocaine Injectable Solution, Saline Solution for Block - Pudendal Neuralgia | Phase 3 | Recruiting | Groupe Hospitalier Diaconesses Croix Saint-Simon | 60 | 2023-12-08 | 2025-05-18 |
| Study Evaluating the Analgesic Efficacy of Capsaicin 8% Patches in Chronic Coccygodynia. Capsaicin 179 Mg Cutaneous Patch, Capsaicin low concentration patch (capsaicin 0,04%, 3,2 mg/cm2) - Coccyx Disorder, Neuropathic Pain | Phase 3 | Recruiting | Nantes University Hospital | 188 | 2023-11-08 | 2026-10-09 |
| Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Traumatic or Post-operative Peripheral Neuropathy Adezunap (AP707), Placebo - Pain, Pain Syndrome | Phase 3 | Unknown | Apurano Pharmaceuticals GmbH | 558 | 2023-11-02 | 2024-01-31 |
| Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any Genesis Adezunap (AP707), Placebo - Pain, Pain Syndrome | Phase 3 | Unknown | Apurano Pharmaceuticals GmbH | 558 | 2023-11-02 | 2024-01-31 |
| Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any Genesis Adezunap, Placebo - Pain, Pain Syndrome | Phase 3 | Unknown | Apurano Pharmaceuticals GmbH | 558 | 2023-11-02 | 2024-01-31 |
| Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Traumatic or Post-operative Peripheral Neuropathy Adezunap (AP707), Placebo - Pain, Pain Syndrome | Phase 3 | Unknown | Apurano Pharmaceuticals GmbH | 558 | 2023-11-02 | 2024-01-31 |
| Efficacy and Safety of Praga Formulation in the Treatment of Neuropathic Pain Praga formulation, Placebo pregabalin 75mg, Placebo Pregabalin 150mg - Neuropathic Pain | Phase 3 | Recruiting | EMS | 136 | 2023-05-15 | 2025-03-14 |
| Ultrasound-Guided Thoracic Paravertebral Block With Steroid and Local Anesthetic for Acute Herpes Zoster: Effects on Pain Control and Prevention of Postherpetic Neuralgia Valacyclovir + Paracetamol (Acetaminophen) + Gabapentin (standard medical therapy), Ultrasound-guided thoracic paravertebral block (TPVB) with bupivacaine 0.25% + methylprednisolone 40 mg - Postherpetic Neuralgia | Phase 3 | Completed | Assiut University | 100 | 2023-03-15 | 2026-01-20 |
| Cannabinoids and an Anti-inflammatory Diet for the Treatment of Neuropathic Pain After Spinal Cord Injury Placebo diet, Anti-inflammatory diet, Nabilone Capsules - Spinal Cord Injuries, Neuropathic Pain | Phase 3 | Completed | Eldon Loh, MD | 14 | 2023-03-01 | 2025-07-22 |
| Brivaracetam to Reduce Neuropathic Pain in Chronic SCI: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial brivaracetam, Placebo - Spinal Cord Injuries, Neuropathic Pain | Phase 3 | Completed | University of Minnesota | 44 | 2023-01-01 | 2026-03-18 |
| Efficacy and Safety of Pregabalin/Tramadol Combination Versus Pregabalin in Acute Pain of Neuropathic Origin Pregabalin 75mg/ Tramadol 50 mg, Pregabalin 75mg - Neuropathic Pain | Phase 3 | Completed | Laboratorios Silanes S.A. de C.V. | 110 | 2022-07-11 | 2023-06-15 |
| Efficacy of an Intraoperative Periradicular Application of Platelet Rich Fibrin (PRF) on the Intensity of Residual Post-surgical Neuropathic Pain After a Surgery for Disc Herniation Treatment - Neuropathic Pain, Chronic Postsurgical Pain | Phase 3 | Recruiting | University Hospital, Strasbourg, France | 60 | 2022-02-23 | 2026-06-08 |
| Efficacy of Soluble Dexamethasone in Refractory Sciatica Dexamethasone phosphate - Sciatica | Phase 3 | Completed | Nantes University Hospital | 109 | 2021-12-16 | 2024-02-01 |
| Effectiveness of Ketamine Administered by Mesotherapy in Complex Regional Pain Syndrome Type 1 (CRPS1) LIDOCAINE 20 mg, LIDOCAINE 20 mg + KETAMINE 20 mg, LIDOCAINE 20 mg + KETAMINE 40 mg - Neuropathic Pain, Complex Regional Pain Syndrome Type 1 | Phase 2 / Phase 3 | Completed | Hospices Civils de Lyon | 31 | 2021-11-05 | 2026-08-10 |
| To Evaluate the Efficacy and Safety of HSK16149 Capsule in Chinese Patients With Postherpetic Neuralgia HSK16149 20mg BID, HSK16149 40mg BID, Placebo BID - Postherpetic Neuralgia | Phase 3 | Completed | Haisco Pharmaceutical Group Co., Ltd. | 372 | 2021-11-01 | 2023-02-27 |
Showing 20 of 122. Sign in to see all of them.
Pain (31) · Neuralgia, Postherpetic (26) · Chronic Pain (14) · Sciatica (14) · Diabetic Neuropathies (13) · Herpes Zoster (10) · Low Back Pain (9) · Peripheral Nervous System Diseases (9) · Pain, Postoperative (8) · Agnosia (7) · Osteoarthritis (6) · Radiculopathy (6) · Spinal Cord Injuries (6) · Back Pain (5)
Nervous System Diseases (122) · Pathological Conditions, Signs and Symptoms (122) · Signs and Symptoms (122) · Neurologic Manifestations (121) · Neuromuscular Diseases (121) · Peripheral Nervous System Diseases (113) · Pain (91) · Pathologic Processes (15) · Endocrine System Diseases (14) · Mononeuropathies (14) · Sciatic Neuropathy (14) · Diabetes Complications (13) · Diabetes Mellitus (13) · Infections (12)
Pregabalin (23) · Capsaicin (6) · Gabapentin (5) · Lidocaine (5) · Ketamine (4) · Bupivacaine (3) · Amitriptyline (2) · Dexamethasone (2) · Lidoderm (2) · Methadone (2) · Methylprednisolone (2) · Morphine (2) · Oxaliplatin (2) · Saline Solution (2) · Tramadol (2)
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (11) · Grünenthal GmbH (5) · NeurogesX (5) · Apurano Pharmaceuticals GmbH (4) · University of Sao Paulo (4) · Assistance Publique - Hôpitaux de Paris (3) · Pfizer (3) · BioDelivery Sciences International (2) · Cephalon (2) · Depomed (2) · Hospices Civils de Lyon (2) · Medical University of Vienna (2) · Nantes University Hospital (2) · Thammasat University (2) · University Hospital, Clermont-Ferrand (2)
United States (34) · France (17) · Canada (11) · Germany (10) · Brazil (8) · Japan (6) · China (5) · Netherlands (5) · Russia (5) · Austria (4) · Belgium (4) · Colombia (4) · Czechia (4) · Denmark (4) · India (4)
Andrew Finn, PharmD (2) · Jeffrey Tobias, MD (2) · Aaron I Vinik, PhD, MD (1) · Antonio Laurenza, M. D. (1) · Anuj Bhatia, MD FRCPC (1) · Bart Nuttin, PhD, MD (1) · Bernardino Clavo, MD, PhD (1) · Bret Berner, Ph.D. (1)
PMID 27448285, PMID 27037091, PMID 27611736, PMID 28072797, PMID 15834546, PMID 15930418, PMID 16186518, PMID 16466610, PMID 18403219, PMID 18419349, PMID 18783971, PMID 18977178, PMID 19260079, PMID 19301937, PMID 19301989, PMID 19366301, PMID 19432499, PMID 19475609, PMID 19480610, PMID 19485723, PMID 19712037, PMID 20433733, PMID 20439572, PMID 20818838, PMID 20863322, PMID 20937130, PMID 21075272, PMID 21087403, PMID 21427067, PMID 21575276, PMID 21848870, PMID 21904098, PMID 22059194, PMID 22067661, PMID 22508732, PMID 22769236, PMID 22828595, PMID 22879908, PMID 23102757, PMID 23345639, PMID 23351618, PMID 23475406, PMID 23549581, PMID 23633406, PMID 23742737, PMID 23917673, PMID 24687190, PMID 24733808, PMID 24907403, PMID 25018648
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