20436 completed, 5196 unknown, 3648 recruiting, 2310 terminated. 12172 Not applicable, 5896 Phase 2, 4533 Phase 1, 3496 Phase 3, 2698 Phase 4.
Follow Endocrine System Diseases: new trials by email Literature Review of Endocrine System Diseases trials Research Report on Endocrine System Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Inhibiting GABA Transaminase to Relieve Obesity Induced Hyperinsulinemia and Insulin Resistance Vigabatrin Pill, Placebo oral tablet - Hyperinsulinism, Insulin Resistance | Phase 2 | Withdrawn | University of Arizona | 2030-04-15 | 2025-07-30 | |
| Certepetide Phase 1b/2a Continuous Infusion Trial in mPDAC certepetide, nab-paclitaxel, gemcitabine - Pancreas Cancer, Pancreatic Carcinoma | Phase 1 / Phase 2 | Withdrawn | Lisata Therapeutics, Inc. | 2030-01-01 | 2025-06-06 | |
| MEDBRIDGE-Guided NCM/CHW Post-Discharge Support for High-Risk T2D Patients MEDBRIDGE-Guided NCM/CHW Post-Discharge Support Intervention - Type 2 Diabetes, Medication Adherence | Not applicable | Not yet recruiting | University of Alabama at Birmingham | 45 | 2029-05-01 | 2026-05-20 |
| Combined Program of Supervised Physical Exercise and Nutritional Counseling in Ovarian Cancer Patients on Frontline Maintenance Treatment With PARP Inhibitors Exercise and dietary recommendations - Ovarian Cancer | Not applicable | Not yet recruiting | Oncare Madrid | 32 | 2028-05-01 | 2026-10-08 |
| Mapping Patient Decision-making in Thyroid Cancer Decision navigation tool - Thyroid Cancer | Not applicable | Not yet recruiting | University of California, Los Angeles | 50 | 2028-04-01 | 2026-07-24 |
| Insul-In This Together: Leveraging Family Support and Diabetes Technology for Adolescents Living With Type 1 Diabetes Insul-In This Together - Diabetes Type 1 | Not applicable | Not yet recruiting | Stanford University | 200 | 2028-01-01 | 2026-10-05 |
| Efficacy, Safety, and Treatment Satisfaction of Once-Weekly Tirzepatide in Obese Type 2 Diabetic Patients Tirzepatide + Standard Therapy (Intervention Group), Standard Oral Antidiabetic Drugs (OADs) - Type 2 Diabetes Mellitus (T2DM), Obesity, Overweight | Not applicable | Not yet recruiting | Akhtar Saeed Medical and Dental College | 52 | 2027-12-12 | 2026-10-29 |
| PAtient Similarity for Decision-Making in Prevention of Cardiovascular Toxicity (PACT): A Feasibility Study Clinical Decision Aid, Standard Care - Heart Failure, Coronary Artery Disease | Not yet recruiting | Medical College of Wisconsin | 60 | 2027-12-01 | 2026-11-03 | |
| Discontinuation of Low-Dose Levothyroxine in Older Adults With Subclinical Hypothyroidism Levothyroxine Pill, Placebo - Hypothyroidism | Phase 4 | Not yet recruiting | Spyridoula Maraka | 138 | 2027-10-01 | 2026-08-26 |
| Endoscopic Ultrasound-Guided Pulsed Electric Field Ablation for the Treatment of Pancreatic Neoplasms Clinical Intervention or Procedure, Electronic Health Record Review, Endoscopic Ultrasound-Guided Fine-Needle Aspiration of the Pancreas - Pancreatic Neoplasm, Pancreatic Neuroendocrine Tumor | Not applicable | Enrolling by invitation | Ohio State University Comprehensive Cancer Center | 12 | 2027-10-01 | 2026-10-13 |
| Testosterone Therapy With or Without Finasteride After Spinal Cord Injury: TRT-SCI Trial testosterone cypionate, finasteride, placebo injection - Spinal Cord Injury, Spinal Cord Injuries | Phase 2 / Phase 3 | Not yet recruiting | VA Office of Research and Development | 300 | 2027-10-01 | 2026-08-04 |
| Role of Endothelial Dysfunction on Exercise Pressor Reflex in Type 2 Diabetes MitoQ (mitoquinol mesylate), Placebo - Type 2 Diabetes (T2DM), Endothelial Dysfunction | Not applicable | Not yet recruiting | Medical College of Wisconsin | 40 | 2027-10-01 | 2026-10-30 |
| Postpartum Semaglutide to Reduce Cardiometabolic Risk After Gestational Diabetes Mellitus Semaglutide (Wegovy) weekly injection - Gestational Diabetes Mellitus (GDM), Metabolic Syndrome | Phase 2 / Phase 3 | Not yet recruiting | University of Massachusetts, Worcester | 226 | 2027-09-01 | 2026-09-28 |
| GLP-1 RA for Stage 1 Type 1 Diabetes Semaglutide, Placebo - Stage 1 Diabetes Mellitus, Type 1 | Phase 2 | Not yet recruiting | Children's Hospital Medical Center, Cincinnati | 15 | 2027-09-01 | 2026-02-24 |
| South Asians With Type 2 Diabetes at Risk for Depression CHW-led T2D Intervention - Type 2 Diabetes | Not applicable | Not yet recruiting | NYU Langone Health | 100 | 2027-08-01 | 2026-05-19 |
| Pre-Clinic Visit Online Education for Thyroid Cancer THRIVE, ACS "After a Thyroid Cancer Diagnosis" Flyer - Thyroid Cancer | Not applicable | Not yet recruiting | Cedars-Sinai Medical Center | 60 | 2027-08-01 | 2026-09-01 |
| Ampligen Combined With SOC Versus SOC Alone Following First-Line Therapy in Subjects With LAPC Rintatolimod - Pancreatic Cancer | Phase 2 | Suspended | AIM ImmunoTech Inc. | 90 | 2027-08-01 | 2026-08-19 |
| Community Health Worker Nutrition Self-Management Support for Cardio-Kidney-Metabolic Health INTEGRATE-CHW, Usual Care - Hypertension (HTN), CKD - Chronic Kidney Disease | Not applicable | Not yet recruiting | Florida International University | 200 | 2027-07-15 | 2026-11-05 |
| Open-Label Extension Study of MHB018A in Patients With Thyroid Eye Disease MHB018A injection - Thyroid Eye Disease (TED) | Phase 3 | Not yet recruiting | Minghui Pharmaceutical (Hangzhou) Ltd | 219 | 2027-07-01 | 2026-06-04 |
| Parathyroid Allotransplantation in Medically Refractory Hypoparathyroidism Parathyroid Allotransplant - Hypoparathyroidism | Not applicable | Withdrawn | University of Alabama at Birmingham | 2027-07-01 | 2026-08-21 |
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Diabetes Mellitus, Type 2 (10036) · Diabetes Mellitus (8225) · Pancreatic Neoplasms (3679) · Diabetes Mellitus, Type 1 (3571) · Ovarian Neoplasms (3265) · Obesity (2054) · Insulin Resistance (1346) · Hypertension (1196) · Diabetic Foot (1032) · Polycystic Ovary Syndrome (954) · Breast Neoplasms (915) · Prediabetic State (915) · Neoplasms (863) · Diabetes, Gestational (831) · Cardiovascular Diseases (802)
Nutritional and Metabolic Diseases (21272) · Metabolic Diseases (20819) · Glucose Metabolism Disorders (20233) · Diabetes Mellitus (14000) · Neoplasms (9441) · Neoplasms by Site (9001) · Endocrine Gland Neoplasms (8818) · Urogenital Diseases (8370) · Female Urogenital Diseases and Pregnancy Complications (7976) · Female Urogenital Diseases (7089) · Pathological Conditions, Signs and Symptoms (6454) · Gonadal Disorders (5927) · Genital Diseases (5530) · Genital Diseases, Female (5034)
Metformin (1087) · Gemcitabine (814) · Insulin Glargine (524) · Paclitaxel (427) · Carboplatin (409) · Sitagliptin Phosphate (399) · Exercise (372) · Insulin (366) · Insulin Aspart (316) · dapagliflozin (307) · Bevacizumab (302) · semaglutide (302) · Standard of Care (282) · Liraglutide (278) · Pioglitazone (264)
Novo Nordisk A/S (888) · AstraZeneca (458) · Eli Lilly and Company (396) · National Cancer Institute (NCI) (361) · Sanofi (294) · Merck Sharp & Dohme LLC (223) · M.D. Anderson Cancer Center (197) · Pfizer (197) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (195) · Mayo Clinic (192) · Assiut University (187) · GlaxoSmithKline (180) · University of Aarhus (176) · University of Colorado, Denver (169) · Memorial Sloan Kettering Cancer Center (167)
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PMID 37185961, PMID 38770818, PMID 39963952, PMID 38682786, PMID 33166419, PMID 37407274, PMID 22236356, PMID 25387217, PMID 25504028, PMID 35472672, PMID 31903692, PMID 32998732, PMID 32501595, PMID 39171639, PMID 26934393, PMID 35044568, PMID 39863139, PMID 22913891, PMID 31606880, PMID 33107592, PMID 34213819, PMID 35170751, PMID 23010561, PMID 26894924, PMID 32267058, PMID 39735417, PMID 26580237, PMID 27402391, PMID 32327102, PMID 35224730, PMID 36542287, PMID 37435938, PMID 24517339, PMID 32306296, PMID 32803882, PMID 33210751, PMID 33327727, PMID 40576086, PMID 41805697, PMID 21450987, PMID 21883806, PMID 22193143, PMID 22234149, PMID 22862847, PMID 23130654, PMID 23186975, PMID 24170235, PMID 24786834, PMID 26232910, PMID 27977934
2015 (124), 2023 (122), 2009 (116), 2017 (108), 2018 (108), 2016 (103), 2014 (100), 2019 (93), 2025 (93), 2008 (90), U10CA027469 (59), 2005 (49), U10CA180868 (48), P30CA033572 (33), P30CA015083 (29)