147 completed, 43 terminated, 19 unknown, 12 recruiting. 242 Phase 2, 20 Phase 1, 15 Phase 3.
Follow Neuralgia: new trials by email Literature Review of Neuralgia trials Research Report on Neuralgia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ketamine and Midazolam Infusions for CRPS: Feasibility Study Ketamine, Midazolam, Normal Saline - Complex Regional Pain Syndromes | Phase 2 | Withdrawn | Stanford University | 2099-01-01 | 2024-11-22 | |
| Safety and Efficacy Study on AFA-281 for the Treatment of Low Back Pain AFA-281 - Lumbosacral Radiculopathy | Phase 2 | Not yet recruiting | Afasci Inc | 408 | 2027-04-01 | 2025-06-26 |
| Efficacy of Botulinum Toxin Versus Placebo on Pain and Health Related Quality of Life of Patients With Piriformis Muscle Syndrome Botulinum Toxin - A injections, Placebo - Piriformis Muscle Syndrome | Phase 2 | Not yet recruiting | Centre Hospitalier Universitaire de Nīmes | 108 | 2027-01-01 | 2026-10-21 |
| Perineural Botulinum Toxin Injection Versus Oral Duloxetine in Relief of Foot Pain in Painful Peripheral Diabetic Neuropathy Botulinum Toxin Type A, Duloxetine, Oral Placebo Tablet - Diabetic Peripheral Neuropathy, Painful Diabetic Neuropathy | Phase 2 | Not yet recruiting | Assiut University | 56 | 2026-11-01 | 2026-10-20 |
| NAC-REPAIR for Post-surgical Pain NAC, NAC 0mg/day (Placebo) - Carpal Tunnel Surgery, Trigger Finger Disorder | Phase 2 | Not yet recruiting | University of Arizona | 80 | 2026-10-15 | 2026-07-17 |
| Psilocybin to Treat Depression in Spinal Cord Injury Psilocybin (Usona Institute) - Spinal Cord Injury, Depression - Major Depressive Disorder | Phase 1 / Phase 2 | Recruiting | James J. Peters Veterans Affairs Medical Center | 30 | 2026-08-06 | 2026-08-10 |
| A Clinical Trial to Evaluate the Efficacy and Safety of HL-1186 Tablet in the Treatment of Postherpetic Neuralgia HL-1186, HL-1186 placebo, Pregabalin capsule - Postherpetic Neuralgia ( PHN ) | Phase 2 | Recruiting | Shanghai Yidian Pharmaceutical Technology Development Co., Ltd. | 200 | 2026-08-01 | 2026-08-11 |
| Functional Brain MRI to Understand Pain Phenotypes in Knee Osteoarthritis blood sampling, Resting-state functional MRI - Gonarthrosis, Neuropathic Pain, Nociceptive Pain | Phase 2 | Not yet recruiting | University Hospital, Clermont-Ferrand | 60 | 2026-07-01 | 2026-06-25 |
| Efficacy of Extracorporeal Shockwave Therapy on Plantar Fasciitis in Patients With Peripheral Neuropathy Extracorporeal shockwave therapy (ESWT) - Neuropathic Pain, Plantar Fasciitis | Phase 2 | Not yet recruiting | National Taiwan University Hospital | 114 | 2026-05-01 | 2026-05-14 |
| Y-4 to Treat the Postherpetic Neuralgia Y-4 tables, Pregabalin - Postherpetic Neuralgia, Y-4 | Phase 2 | Recruiting | Neurodawn Pharmaceutical Co., Ltd. | 160 | 2026-02-02 | 2026-05-13 |
| Analgesic Efficacy and Safety of Topical VMD-3866 Gel in Management of Pain Induced by Chemotherapy (CIPN) VMD-3866 Gel, Placebo Gel - Chemotherapy-induced Peripheral Neuropathy, Chemotherapy-induced Neuropathic Pain | Phase 2 | Recruiting | VM Therapeutics LLC | 16 | 2025-12-12 | 2026-10-21 |
| Pain Outcomes After Digital Amputation Using Tulavi Allay™ Nerve Cap Tulavi allay Nerve Cap - Neuroma, Neuropathic Pain | Phase 2 | Recruiting | Massachusetts General Hospital | 20 | 2025-09-20 | 2026-04-17 |
| Ginger Root Extract for Sciatic Pain Individuals Placebo, Ginger - Neuropathic Pain, Sciatic Pain | Phase 2 | Recruiting | Leslie Shen | 80 | 2025-07-01 | 2025-12-30 |
| Effects of CBD/CBD-A Oral Extract on Resting-state EEG and Neuropathic Pain Symptoms After SCI CBD/CBD-A, Placebo - SCI - Spinal Cord Injury, Neuropathic Pain | Phase 1 / Phase 2 | Completed | University of Miami | 6 | 2025-06-16 | 2026-08-14 |
| Topical Herbal Medicine for Chemotherapy-Induced Peripheral Neuropathy menthol-based hand and foot gloves, Sham menthol-based hand and foot gloves - Chemotherapy-induced Peripheral Neuropathy (CIPN) | Phase 2 | Active not recruiting | Taiwan Municipal An-Nan Hospital-China Medical University | 40 | 2025-05-12 | 2026-07-09 |
| Crisugabalin for Radiotherapy-Related Neuropathic Pain Crisugabalin, Pregabalin - Neuropathic Pain | Phase 2 | Recruiting | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 172 | 2025-05-07 | 2025-05-18 |
| Psilocybin for Enhanced Analgesia in Chronic nEuropathic PAIN Psilocybin, Active Placebo - Chronic Neuropathic Pain, Pain Management | Phase 2 | Recruiting | Unity Health Toronto | 30 | 2025-03-05 | 2025-03-30 |
| Efficacy and Safety Study of Halneuron in the Treatment of Chemotherapy-Induced Neuropathic Pain Halneuron, Placebo, Halneuron (Open Label Extension) - Chemotherapy Induced Neuropathic Pain, Chemotherapy Induced Pain Neuropathy | Phase 2 | Active not recruiting | Dogwood Therapeutics Inc. | 240 | 2025-02-21 | 2026-09-16 |
| A Study of ONO-1110 in Patients With Postherpetic Neuralgia ONO-1110, Placebo - Postherpetic Neuralgia | Phase 2 | Completed | Ono Pharmaceutical Co., Ltd. | 142 | 2025-02-12 | 2026-07-15 |
| Non-Invasive Pulsed Radiofrequency for the Treatment of Neuropathic Pain Active Treatment, Non-active Treatment - Pain, Nerve | Phase 2 / Phase 3 | Recruiting | Stanford University | 95 | 2024-11-01 | 2026-04-24 |
Showing 20 of 242. Sign in to see all of them.
Neuralgia, Postherpetic (68) · Pain (48) · Diabetic Neuropathies (25) · Herpes Zoster (21) · Sciatica (20) · Chronic Pain (17) · Peripheral Nervous System Diseases (17) · Agnosia (12) · Low Back Pain (11) · Radiculopathy (10) · Diabetes Mellitus (9) · Spinal Cord Injuries (9) · Back Pain (6) · Complex Regional Pain Syndromes (6)
Neurologic Manifestations (242) · Pathological Conditions, Signs and Symptoms (242) · Signs and Symptoms (242) · Nervous System Diseases (241) · Neuromuscular Diseases (241) · Peripheral Nervous System Diseases (225) · Pain (194) · Endocrine System Diseases (30) · Diabetes Complications (25) · Mononeuropathies (24) · Infections (22) · Virus Diseases (22) · DNA Virus Infections (21) · Herpesviridae Infections (21)
Pregabalin (17) · Lidocaine (9) · Saline Solution (9) · Botulinum Toxins, Type A (8) · Ketamine (7) · nabiximols (6) · Gabapentin (5) · Capsaicin (4) · Duloxetine Hydrochloride (4) · 1-(((alpha-isobutanoyloxyethoxy)carbonyl)aminomethyl)-1-cyclohexaneacetic acid (3) · Dextromethorphan (3) · Dronabinol (3) · EMA400 (3) · Sodium Chloride (3) · 2-(acetylamino)-3-methoxy-N-(phenylmethyl)-, (2R)- (2)
NeurogesX (7) · University Hospital, Clermont-Ferrand (7) · GlaxoSmithKline (5) · National Institute of Dental and Craniofacial Research (NIDCR) (5) · Pfizer (5) · Allergan (4) · AstraZeneca (4) · UCB Pharma (4) · Washington University School of Medicine (4) · Center for Medicinal Cannabis Research (3) · Grünenthal GmbH (3) · University Hospital, Geneva (3) · Virginia Commonwealth University (3) · XenoPort, Inc. (3) · AbbVie (prior sponsor, Abbott) (2)
United States (116) · France (31) · Germany (27) · Canada (22) · United Kingdom (19) · Poland (18) · Czechia (13) · Denmark (13) · Australia (12) · Spain (12) · China (8) · Hungary (8) · South Korea (8) · Italy (7) · Japan (7)
Bror Jonzon (2) · Randall W Moreadith, MD, PhD (2) · Robert H Dworkin, Ph.D. (2) · Simon Haroutounian, PhD (2) · Thomas Bryce, MD (2)
PMID 33675631, PMID 11145807, PMID 11402097, PMID 12384756, PMID 12897484, PMID 15030944, PMID 15115710, PMID 15234492, PMID 15454701, PMID 15834546, PMID 16192528, PMID 16371894, PMID 17414235, PMID 18003941, PMID 18289791, PMID 18403219, PMID 18430745, PMID 18546285, PMID 19194764, PMID 19260079, PMID 19387178, PMID 19469706, PMID 19734516, PMID 19791831, PMID 20194147, PMID 20506391, PMID 20538187, PMID 20627413, PMID 21356040, PMID 21427067, PMID 21575276, PMID 21612836, PMID 21674151, PMID 21848870, PMID 21868066, PMID 22182397, PMID 22370242, PMID 22508732, PMID 22879908, PMID 23102757, PMID 23186035, PMID 23370086, PMID 23549581, PMID 23577077, PMID 24102928, PMID 24550805, PMID 24641437, PMID 24687190, PMID 24733808, PMID 24824524
2018 (4), 2016 (3), 2008 (2), 2009 (2), 2014 (2), 2017 (2), 2019 (2), 2004 (1), 2005 (1), 2015 (1), 2023 (1), K23NS050485 (1), R01AR053960 (1), R01DA038634 (1), R44DA040378 (1)