128 completed, 21 unknown, 16 recruiting, 16 terminated. 68 Phase 2, 44 Not applicable, 26 Phase 3, 19 Phase 4, 14 Phase 1.
Follow Neuralgia, Postherpetic: new trials by email Literature Review of Neuralgia, Postherpetic trials Research Report on Neuralgia, Postherpetic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Simultaneous Engagement of Networks for Alleviating Pain (SENAP) PFM-guided cortical stimulation - Neuropathic Pain, Postherpetic Neuralgia | Phase 1 | Not yet recruiting | University of Minnesota | 20 | 2026-11-01 | 2026-07-23 |
| A Clinical Trial to Evaluate the Efficacy and Safety of HL-1186 Tablet in the Treatment of Postherpetic Neuralgia HL-1186, HL-1186 placebo, Pregabalin capsule - Postherpetic Neuralgia ( PHN ) | Phase 2 | Recruiting | Shanghai Yidian Pharmaceutical Technology Development Co., Ltd. | 200 | 2026-08-01 | 2026-08-11 |
| Pharmacokinetics of Y-4 Tablets With Pregabalin Capsules and Riluzole Tablets in U.S. Healthy Participants Y-4 tablet, Pregabalin capsule, Riluzole tablet - Healthy Male and Female Subjects | Phase 1 | Not yet recruiting | Neurodawn Pharmaceutical Co., Ltd. | 11 | 2026-06-30 | 2026-06-01 |
| Extended-release Pregabalin for the Treatment of Neuropathic Pain in Patients With Diabetic Peripheral Neuropathy and Postherpetic Neuralgia Experimental: Pregabalin XR, Comparator: Dorene Tabs, Comparator placebo - Diabetic Neuropathy, Neuropathic Pain | Phase 3 | Recruiting | Brainfarma Industria Química e Farmacêutica S/A | 348 | 2026-06-18 | 2026-07-20 |
| Efficacy and Safety of High-Concentration 35 kDa Hyaluronan Gel for Herpes Zoster-Associated Pain 10% High-Concentration 35 kDa Hyaluronan (HA35) Topical Analgesic Gel - Herpes Zoster, Zoster-Associated Pain | Not applicable | Completed | Nakhia Impex LLC | 30 | 2026-05-01 | 2026-09-23 |
| Y-4 to Treat the Postherpetic Neuralgia Y-4 tables, Pregabalin - Postherpetic Neuralgia, Y-4 | Phase 2 | Recruiting | Neurodawn Pharmaceutical Co., Ltd. | 160 | 2026-02-02 | 2026-05-13 |
| Efficacy of Transcutaneous Pulsed Radiofrequency in Postherpetic Neuralgia Transcutaneous Pulsed Radiofrequency - Postherpetic Neuralgia, Chronic Pain | Recruiting | Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization | 35 | 2026-02-01 | 2026-02-05 | |
| Brain Stimulation for Postherpetic Neuralgia: A Randomized Sham-Controlled Trial Non-invasive transcranial stimulation, Sham Non-invasive transcranial stimulation - Postherpetic Neuralgia | Not applicable | Not yet recruiting | Huazhong University of Science and Technology | 94 | 2026-01-20 | 2026-01-20 |
| The Analgesic Efficacy and Safety of Venlafaxine for Prevention of Postherpetic Neuralgia in Patients With Acute Herpes Zoster Venlafaxine combined conventional therapy, Conventional therapy - Herpes Zoster, Pain | Not applicable | Recruiting | Beijing Tiantan Hospital | 832 | 2025-12-15 | 2026-09-02 |
| Pulsed Radiofrequency in Post Herptic Neuralgia Irregular Pulsed Radiofrequency (STP), regular pulsed Radiofrequency - Postherpetic Neuralgia (PHN) | Not applicable | Not yet recruiting | Sohag University | 100 | 2025-10-01 | 2025-10-06 |
| Transcutaneous Auricular Vagus Nerve Stimulation on Post-Herpetic Neuralgia transcutaneous auricular vagus nerve stimulation (taVNS), traditional medical treatment for PHN - Post Herpetic Neuralgia (PHN) | Not applicable | Recruiting | Mohamed Hosny Ismail Easa | 34 | 2025-09-07 | 2026-03-18 |
| Comparison Between the Efficacy of Ultrasound-guided Erector Spinae Plane Block and Conventional Treatment for Pain Management in Patients With Post-herpetic Neuralgia erector spinae plane block - Post-Herpetic Neuralgia | Not applicable | Recruiting | Alexandria University | 60 | 2025-08-01 | 2025-12-01 |
| Effectiveness of Ultrasonography-Guided Serratus Posterior Superior Intercostal Plane Block in Thoracic Postherpetic Neuralgia: A Retrospective Cohort Study Postherpetic Neuralgia ( PHN ), Ultrasound Guided, Block, Ultrasound Guided Injection | Completed | Kanuni Sultan Suleyman Training and Research Hospital | 34 | 2025-07-01 | 2025-12-12 | |
| Early Screening Markers of Herpes Zoster Neuralgia Extract the serum and feces of the patients for standard screening of early biomarkers, Meningeal lymphatic vessel imaging - Postherpetic Neuralgia ( PHN ), Lymphatic System Disorder | Not yet recruiting | Tongji Hospital | 150 | 2025-07-01 | 2025-06-26 | |
| Electroacupuncture for PHN: Efficacy and Biomarker Evaluation in a Multicenter, Randomized, Sham-Controlled Trial Protocol Electroacupuncture (Hans-100A, Nanjing Jisheng Medical Technology, China), Pharmacotherapy：① Pregabalin ( Lyrica™ ，Pfizer Inc. America) ② Methylcobalamin ( Mecobalamin tablets， Weicai (China) Pharmaceutical Co., Ltd， China）, Streitberger Placebo Needle Set ( Asiamed ) - Postherpetic Neuralgia ( PHN ) | Not applicable | Not yet recruiting | Dexiong Han | 207 | 2025-07-01 | 2025-07-09 |
| Erector Spinae Plane Block Versus Transcutaneous Radiofrequency in Postherpetic Neuralgia Erector Spinae Plane Block - Postherpetic Neuralgia, Neuropathic Pain | Recruiting | Diskapi Teaching and Research Hospital | 50 | 2025-06-01 | 2026-02-25 | |
| The Effectiveness of Ultra-Sound Guided Erector Spinae Block With Betamethasone for Management of Truncal Chronic Post Herpetic Neuralgia. Medical management regimen, Erector spinae plane (ESP) block - Postherpetic Neuralgia, Chronic Pain | Not applicable | Recruiting | Cairo University | 40 | 2025-05-01 | 2025-06-05 |
| Comparative Efficacy of Pregabalin and Lacosamide in Patients With Herpes Zoster and Post Herpetic Neuralgia Pregabalin, Lacosamide - Herpes Zoster (HZ), Post Herpetic Neuralgia (PHN) | Not applicable | Recruiting | CMH Kharian Medical College | 50 | 2025-04-10 | 2025-05-14 |
| Esketamine Combined Pregabalin and Duloxetine for Postherpetic Neuralgia esketamine group, control group - Postherpetic Neuralgia | Not applicable | Recruiting | Beijing Tiantan Hospital | 150 | 2025-04-01 | 2025-04-27 |
| Effectiveness of Warm Acupuncture in Patients with Postherpetic Neuralgia Warm acupuncture and Gabapentin, Gabapentin - Postherpetic Neuralgia ( PHN ) | Not applicable | Not yet recruiting | University of Medicine and Pharmacy at Ho Chi Minh City | 36 | 2025-04-01 | 2025-03-25 |
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Herpes Zoster (54) · Neuralgia (51) · Pain (29) · Chronic Pain (16) · Diabetic Neuropathies (15) · Complex Regional Pain Syndromes (12) · Peripheral Nervous System Diseases (11) · Pain, Postoperative (9) · Peripheral Nerve Injuries (6) · Chickenpox (4) · Osteoarthritis (4) · Radiculopathy (4) · Trigeminal Neuralgia (4) · Agnosia (3)
Nervous System Diseases (195) · Neurologic Manifestations (195) · Neuromuscular Diseases (195) · Pathological Conditions, Signs and Symptoms (195) · Signs and Symptoms (195) · Peripheral Nervous System Diseases (184) · Pain (166) · Neuralgia (144) · Infections (54) · Varicella Zoster Virus Infection (54) · DNA Virus Infections (53) · Herpesviridae Infections (53) · Virus Diseases (53) · Diabetes Complications (15) · Endocrine System Diseases (15)
Pregabalin (20) · Lidocaine (9) · Gabapentin (8) · Capsaicin (5) · Valacyclovir (5) · Botulinum Toxins, Type A (4) · Lidoderm (4) · Electroacupuncture (3) · 1-(((alpha-isobutanoyloxyethoxy)carbonyl)aminomethyl)-1-cyclohexaneacetic acid (2) · 2-(acetylamino)-3-methoxy-N-(phenylmethyl)-, (2R)- (2) · Data Collection (2) · Drug Evaluation (2) · Duloxetine Hydrochloride (2) · EMA400 (2) · Etoricoxib (2)
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PMID 27037091, PMID 36729473, PMID 15930418, PMID 1646585, PMID 16466610, PMID 17258129, PMID 18164488, PMID 18419349, PMID 18977178, PMID 19195785, PMID 19366301, PMID 19432499, PMID 19469706, PMID 19475609, PMID 19712037, PMID 20439572, PMID 20487048, PMID 20818838, PMID 20863322, PMID 21075272, PMID 21087403, PMID 21185118, PMID 21356040, PMID 21422774, PMID 21482862, PMID 21904098, PMID 22151211, PMID 22182397, PMID 22769236, PMID 22828595, PMID 22996865, PMID 23633406, PMID 23917673, PMID 24102928, PMID 25594611, PMID 26359327, PMID 26478818, PMID 26695349, PMID 26947719, PMID 27153360, PMID 27448285, PMID 27611736, PMID 27753650, PMID 27917531, PMID 28072797, PMID 28158151, PMID 28988331, PMID 29086340, PMID 29189275, PMID 29309521
2009 (3), 2018 (2), 2004 (1), 2005 (1), 2008 (1), 2014 (1), R43AR052998 (1), R44NS059140 (1), UH3NS115631 (1)