178 completed, 29 recruiting, 23 unknown, 17 active not recruiting. 66 Phase 3, 64 Phase 2, 50 Not applicable, 41 Phase 1, 28 Phase 4.
Follow Herpes Zoster: new trials by email Literature Review of Herpes Zoster trials Research Report on Herpes Zoster
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study Exploring the Effect of Adjuvanted RZV or RSVPreF3 Vaccines on Coronary Plaque Progression in Adults >=50 Years of Age at Risk for Cardiovascular Events Placebo, Adjuvanted RZV vaccine, Adjuvanted RSVPreF3 vaccine - Cardiovascular Disease | Phase 2 | Not yet recruiting | GlaxoSmithKline | 450 | 2026-10-23 | 2026-10-20 |
| Comparative Study of Two Vaccination Schedules for the Subunit Herpes Zoster Vaccine in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disease Patients Treated With Anti-CD20 Therapy: an Open-label Randomised Controlled Trial Two-dose M0-M2 vaccination schedule, Two-dose M0-M6 vaccination schedule - Vaccine, Varicella-zoster Virus | Phase 4 | Not yet recruiting | University Hospital, Toulouse | 160 | 2026-10-20 | 2026-09-14 |
| Shingrix in Patients With Rheumatic Diseases: a Double-blind Placebo-controlled RCT recombinant subunit herpes zoster vaccine - Herpes Zoster | Phase 4 | Withdrawn | Tuen Mun Hospital | 2026-09-29 | 2026-10-01 | |
| Efficacy and Safety of High-Concentration 35 kDa Hyaluronan Gel for Herpes Zoster-Associated Pain 10% High-Concentration 35 kDa Hyaluronan (HA35) Topical Analgesic Gel - Herpes Zoster, Zoster-Associated Pain | Not applicable | Completed | Nakhia Impex LLC | 30 | 2026-05-01 | 2026-09-23 |
| A Phase 2 Study to Describe the Safety, Reactogenicity, and Immunogenicity of Herpes Zoster IN001 mRNA Vaccine (IN001) in Healthy Participants HZ Vaccine (IN001), Shingrix - Herpes Zoster | Phase 2 | Not yet recruiting | Shenzhen Shenxin Biotechnology Co., Ltd | 480 | 2026-05-01 | 2025-10-07 |
| Recombinant Herpes Zoster Vaccine for Prevention of Cardiovascular Events and Dementia Recombinant Herpes Zoster Vaccine (Shingrix) - Cardiovascular Disease, Dementia | Phase 4 | Active not recruiting | Tor Biering-Sørensen | 168460 | 2026-04-28 | 2026-10-14 |
| Safety and Immunogenicity of CVI-VZV-001 in Adults Aged 50 Years and Above Shingrix, CVI-VZV-001 - Herpes Zoster | Phase 2 | Not yet recruiting | Aribio Lab Co., Ltd. | 135 | 2026-04-01 | 2026-03-19 |
| A Study to Evaluate the Effect of Recombinant Zoster Vaccine on New Diagnosis of Dementia in an Older Adult Population Aged 76 Years or Older in Finland Recombinant zoster vaccine, Placebo - Herpes Zoster | Phase 4 | Recruiting | GlaxoSmithKline | 33609 | 2026-03-31 | 2026-05-12 |
| Long-term Effectiveness of the Live Attenuated Herpes Zoster Vaccine Attenuated Zoster Vaccine, Live, Matched Placebo Without Live Virus - Herpes Zoster | Recruiting | Jiangsu Province Centers for Disease Control and Prevention | 24740 | 2026-03-06 | 2026-05-13 | |
| Immunogenicity and Safety of SYS6017 in the Participants Aged 40 Years and Above A zoster mRNA vaccine SYS6017, Placebo, Active Comparator Vaccine - Herpes Zoster | Phase 2 | Not yet recruiting | CSPC Megalith Biopharmaceutical Co.,Ltd. | 800 | 2026-01-10 | 2026-01-21 |
| Study to Evaluate the Safety and Immunogenicity of a Lyophilized Herpes Zoster Virus mRNA Vaccine Low-dose experimental vaccine, High-dose experimental vaccine, Active-controlled vaccine A - Herpes Zoster, mRNA Vaccine | Phase 1 / Phase 2 | Recruiting | Sinovac Biotech Co., Ltd | 519 | 2026-01-06 | 2026-02-10 |
| The Analgesic Efficacy and Safety of Flurbiprofen Patch in Patients With Herpes Zoster Flurbiprofen patch combined with conventional therapy group, Conventional therapy group - Herpes Zoster, Pain | Not applicable | Recruiting | Beijing Tiantan Hospital | 750 | 2025-12-15 | 2026-01-27 |
| The Analgesic Efficacy and Safety of Mirogabalin in Patients With Herpes Zoster Mirogabalin combined conventional therapy, Conventional therapy - Herpes Zoster, Mirogabalin | Not applicable | Recruiting | Beijing Tiantan Hospital | 750 | 2025-12-15 | 2026-03-19 |
| The Analgesic Efficacy and Safety of Crisugabalin in Patients With Herpes Zoster Crisugabalin combined conventional therapy, Conventional therapy - Herpes Zoster, Pain | Not applicable | Recruiting | Beijing Tiantan Hospital | 750 | 2025-12-15 | 2026-01-14 |
| The Analgesic Efficacy and Safety of Venlafaxine for Prevention of Postherpetic Neuralgia in Patients With Acute Herpes Zoster Venlafaxine combined conventional therapy, Conventional therapy - Herpes Zoster, Pain | Not applicable | Recruiting | Beijing Tiantan Hospital | 832 | 2025-12-15 | 2026-09-02 |
| The Analgesic Efficacy and Safety of Desvenlafaxine in Patients With Herpes Zoster Desvenlafaxine combined conventional therapy, Conventional therapy - Herpes Zoster, Pain | Not applicable | Recruiting | Beijing Tiantan Hospital | 750 | 2025-12-15 | 2026-01-23 |
| The Analgesic Efficacy and Safety of Baclofen in Patients With Herpes Zoster Baclofen combined conventional therapy, Conventional therapy - Herpes Zoster, Pain | Not applicable | Recruiting | Beijing Tiantan Hospital | 750 | 2025-12-15 | 2026-01-30 |
| A Phase III Clinical Trial to Evaluate Long-Term Protective Efficacy of Recombinant Zoster Vaccine (CHO Cell) Recombinant Zoster Vaccine (CHO Cell), NaCl solution Placebo - Herpes Zoster | Phase 3 | Active not recruiting | MAXVAX Biotechnology Limited Liability Company | 12000 | 2025-12-15 | 2026-10-15 |
| The Analgesic Efficacy and Safety of Tulodesvenlafaxine in Patients With Herpes Zoster Conventional therapy group, Tulodesvenlafaxine combined conventional therapy - Herpes Zoster, Pain | Not applicable | Recruiting | Beijing Tiantan Hospital | 750 | 2025-12-15 | 2026-01-27 |
| The Analgesic Efficacy and Safety of Loxoprofen Sodium Patch in Patients With Herpes Zoster Conventional therapy group, Loxoprofen sodium patch combined with conventional therapy group - Herpes Zoster, Pain | Not applicable | Recruiting | Beijing Tiantan Hospital | 750 | 2025-12-15 | 2026-01-30 |
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