1002 completed, 328 recruiting, 265 unknown, 110 terminated. 1223 Not applicable, 220 Phase 2, 146 Phase 1, 70 Phase 3, 52 Phase 4.
Follow Spinal Cord Injuries: new trials by email Literature Review of Spinal Cord Injuries trials Research Report on Spinal Cord Injuries
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Patient-centered Assessment of the Effects of Powered Exoskeleton Use in People With Spinal Cord Injury Rehabilitation - Spinal Cord Injuries | Not applicable | Suspended | Istituto Nazionale Assicurazione contro gli Infortuni sul Lavoro | 18 | 2030-01-01 | 2026-03-27 |
| Device for Bladder Control for Men With SCI Noninvasive electrical stimulation device to improve bladder control - Neurogenic Bladder | Phase 1 / Phase 2 | Not yet recruiting | VA Office of Research and Development | 12 | 2028-06-01 | 2026-06-25 |
| Efficacy of iPSC-Derived Motor Neuron Cells (XS228) in Subacute Spinal Cord Injury: A Phase II Randomized Controlled Trial Allogeneic Human Induced Pluripotent Stem Cell (iPSC)-Derived Motor Neuron Progenitor Cells, Placebo - Spinal Cord Injury, Safety | Phase 2 | Not yet recruiting | XellSmart Bio-Pharmaceutical (Suzhou) Co., Ltd. | 60 | 2028-05-25 | 2025-11-25 |
| Testosterone Therapy With or Without Finasteride After Spinal Cord Injury: TRT-SCI Trial testosterone cypionate, finasteride, placebo injection - Spinal Cord Injury, Spinal Cord Injuries | Phase 2 / Phase 3 | Not yet recruiting | VA Office of Research and Development | 300 | 2027-10-01 | 2026-08-04 |
| Combining Low Oxygen Therapy and an Adenosine A2a Receptor Antagonist to Improve Functional Mobility After Spinal Cord Injury Istradefylline, low oxygen therapy - Spinal Cord Injuries, Myelopathy | Phase 1 / Phase 2 | Not yet recruiting | Randy Trumbower, PT, PhD | 40 | 2027-09-01 | 2026-03-20 |
| Empowerment Program to Reduce Treatment of Asymptomatic Bacteriuria in Veterans With Spinal Cord Injury Empowerment Program - Spinal Cord Injury, Spinal Cord Disease | Not applicable | Not yet recruiting | VA Office of Research and Development | 30 | 2027-08-02 | 2026-08-19 |
| Cardiocentric Inotropic Optimization in Spinal Cord Injury Dobutamine crossover - SCI - Spinal Cord Injury | Early Phase 1 | Not yet recruiting | University of British Columbia | 8 | 2027-06-01 | 2026-10-13 |
| Combined rTMS and tSCS for Upper Limb Recovery in Cervical SCI Transcranial Magnetic Stimulation, Transcutaneous Spinal Cord Stimulation - Spinal Cord Injuries (SCI) | Not applicable | Not yet recruiting | National University Hospital, Singapore | 24 | 2027-03-30 | 2026-05-14 |
| Xo-Motion R Exoskeleton in SCI-Adoption Study XoMotionR- assisted locomotor training - Spinal Cord Injury | Not applicable | Not yet recruiting | University of Alberta | 16 | 2027-03-01 | 2026-09-16 |
| NeuroSuitUp: Neurorehabilitation Through Synergistic Man-machine Interfaces Brain-Computer Interface control of robotic arms with augmented reality, Serious game with augmented reality - Spinal Cord Injuries | Not applicable | Enrolling by invitation | Aristotle University Of Thessaloniki | 20 | 2027-02-01 | 2026-10-28 |
| Functional Electrical Stimulation Plus High Intensity Interval Training at Home FES+HIIT@Home - Spinal Cord Injuries (SCI) | Not applicable | Not yet recruiting | University Health Network, Toronto | 24 | 2027-01-02 | 2026-10-26 |
| Combined TMS-tSCS for Lower Limb Rehabilitation in Chronic Incomplete SCI Transcranial Magnetic Stimulation, Transcutaneous Spinal Cord Stimulation - Spinal Cord Injuries (SCI) | Not applicable | Not yet recruiting | National University Hospital, Singapore | 24 | 2027-01-01 | 2026-05-19 |
| Interfacing With NeuroTechnology to Expand Neural Throughput (INTENT) INTENT Neural Interface System - Tetraplegia/Tetraparesis, Amyotrophic Lateral Sclerosis (ALS) | Not applicable | Recruiting | Johns Hopkins University | 5 | 2027-01-01 | 2026-10-09 |
| Cuneiform Nucleus (CnF) Deep Brain Stimulation for Gait Facilitation Following Spinal Cord Injury Deep Brain Stimulation (DBS), Deep Brain Stimulation (DBS) Device Implant Procedure, Training Sessions - Spinal Cord Injuries | Not applicable | Recruiting | University of Miami | 6 | 2026-12-31 | 2026-10-29 |
| Assessment of Safety and Effectiveness of Spatial StimelMD (SSMD) in Subjects With Upper Limb Neuromotor Impairments SSMD, Functional Electrical Stimulation (FES) - Stroke, TBI | Not applicable | Not yet recruiting | Motion Informatics LTD | 120 | 2026-12-30 | 2026-02-11 |
| NO AD: Use of Nitric Oxide (NO) Donors for the Prevention of Autonomic Dysreflexia (AD) During Bowel Care Following SCI Glyceryl Trinitrate Only Product in Oromucosal Dose Form, Placebo sublingual spray - Spinal Cord Injuries, Autonomic Dysreflexia | Phase 2 | Not yet recruiting | Simon Fraser University | 26 | 2026-12-01 | 2026-04-23 |
| Dorsal Root Ganglion Stimulation After Lower Motor Neuron Damage Abbot Dorsal Root Ganglion Neurostimulator - Spinal Cord Injuries, Lower Motor Neuron Disease | Not applicable | Not yet recruiting | Peter J. Grahn, Ph.D. | 1 | 2026-12-01 | 2026-09-15 |
| The Effects of Eccentric Compared to Standard Strength Training in Primary Spinal Cord Injury Rehabilitation Eccentric (KREHA) training, Standard clinical routine strength (STAN) training - Spinal Cord Injury | Not applicable | Not yet recruiting | Swiss Paraplegic Research, Nottwil | 20 | 2026-12-01 | 2026-09-28 |
| Transcutaneous Spinal Cord Stimulation for Blood Pressure Augmentation Immediately After Spinal Cord Injury Spinal Cord Stimulation - Spinal Cord Injury Cervical, Spinal Cord Injuries (SCI) | Not applicable | Not yet recruiting | Markey Olson | 20 | 2026-12-01 | 2026-10-21 |
| Olfactory Cell Transplantation and Intensive Rehabilitation to Repair Chronic Spinal Cord Injury Olfactory Ensheathing Cell, biological intervention, rehabilitation - Spinal Cord Injury, Neurological Conditions | Phase 1 | Not yet recruiting | Dr Brent McMonagle | 30 | 2026-12-01 | 2026-10-21 |
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Quadriplegia (155) · Stroke (123) · Paraplegia (100) · Neuralgia (74) · Multiple Sclerosis (70) · Spinal Cord Diseases (66) · Muscle Spasticity (65) · Motor Activity (62) · Paralysis (59) · Urinary Bladder, Neurogenic (58) · Spinal Cord Compression (46) · Pain (45) · Brain Injuries, Traumatic (43) · Chronic Pain (42)
Central Nervous System Diseases (1968) · Nervous System Diseases (1960) · Wounds and Injuries (1953) · Trauma, Nervous System (1929) · Spinal Cord Diseases (1918) · Pathological Conditions, Signs and Symptoms (649) · Signs and Symptoms (609) · Neurologic Manifestations (520) · Brain Diseases (195) · Vascular Diseases (185) · Cardiovascular Diseases (183) · Paralysis (178) · Musculoskeletal Diseases (159) · Neuromuscular Diseases (149) · Cerebrovascular Disorders (134)
Exercise (21) · Transcranial Direct Current Stimulation (21) · Rehabilitation (16) · Transcranial Magnetic Stimulation (16) · Botulinum Toxins, Type A (14) · Physical Therapy Modalities (13) · salicylhydroxamic acid (11) · Electric Stimulation (10) · Therapeutics (10) · Control Groups (9) · High-Intensity Interval Training (9) · Radiosurgery (9) · Brain-Computer Interfaces (8) · Pregabalin (8) · Resistance Training (8)
VA Office of Research and Development (75) · Shirley Ryan AbilityLab (45) · Swiss Paraplegic Research, Nottwil (45) · University of Miami (45) · University of British Columbia (44) · US Department of Veterans Affairs (42) · Kessler Foundation (40) · James J. Peters Veterans Affairs Medical Center (38) · Spaulding Rehabilitation Hospital (25) · University of Zurich (24) · University of Washington (23) · University of Louisville (22) · Washington University School of Medicine (21) · University Health Network, Toronto (20) · Craig Hospital (19)
United States (950) · Canada (197) · Switzerland (109) · China (75) · France (67) · Turkey (Türkiye) (63) · United Kingdom (63) · Spain (55) · Denmark (35) · Italy (33) · Taiwan (33) · Brazil (31) · Germany (22) · South Korea (22) · Netherlands (20)
Mark S Nash, PhD (12) · William Bauman, MD (11) · Andrei Krassioukov, MD,PhD,FRCPC (7) · Edelle C Field-Fote, PT, PhD (6) · Gail F Forrest, PhD (6) · Jocelyne Bloch, MD (6) · Kerri A Morgan, PhD (6) · Nancy Rocheleau, Program Analyst (6) · Randy D Trumbower, PT, PhD (6) · Thomas J Schnitzer, MD, PhD (6) · Trevor A. Dyson-Hudson, M.D. (6) · Argyrios Stampas, MD (5) · Gobinathan Chandran, MBBS (5) · Jill Wecht, EdD (5) · John Fryer, Ph.D. Asst. Director (5)
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2023 (5), 2019 (4), 2016 (3), 2018 (3), 2025 (3), 2017 (2), R01HD080205 (2), R01HD081274 (2), R01HL150581 (2), R01NS041503 (2), U01DC017844 (2), 1DP2DC021055 (1), 1IK1RX004538-01A1 (1), 1IK1RX004813 (1), 1IK1RX005028-01 (1)