21 completed, 4 terminated, 1 active not recruiting, 1 unknown. 13 Phase 4, 4 Not applicable, 4 Phase 3, 3 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 13 | Completed 9, Terminated 3, Active not recruiting 1 |
| Not applicable | 4 | Completed 3, Unknown 1 |
| Phase 3 | 4 | Completed 3, Terminated 1 |
| Phase 1 | 3 | Completed 3 |
| Phase 2 | 3 | Completed 3 |
Follow this drug Literature Review of Lidoderm trials Research Report on Lidoderm
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intralipid® 20% for Reversal of Local Anesthetics Lidocaine 2%, Lidocaine 1%, Bupivacaine 0.25% - Anesthesia, Local | Phase 4 | Active not recruiting | Hospital for Special Surgery, New York | 18 | 2019-07-26 | 2025-12-08 |
| Pharmacokinetics of Lidocaine in Healthy Adults Lidocaine 5% patch, Lidocaine hydrochloride, Lidoderm 5% patch - Healthy | Phase 4 | Completed | Nicole K Brogden | 23 | 2018-03-14 | 2021-11-01 |
| Post-Op Lidocaine Patch Lidoderm 5 % Topical Patch, Sham Topical Patch - Pain, Postoperative | Phase 4 | Completed | Oregon Health and Science University | 50 | 2018-03-13 | 2020-03-11 |
| Adhesion Performance Study of Lidocaine Topical System 1.8% Compared to Lidocaine Patch 5% and Lidocaine Medicated Plaster 5% in Healthy, Adult, Human Subjects Lidocaine patch 1.8%, Lidocaine patch 5%, Lidocaine medicated plaster 5% - Healthy | Phase 1 | Completed | Scilex Pharmaceuticals, Inc. | 47 | 2017-02-14 | 2020-03-24 |
| Comparative Pharmacokinetic Study of Lidocaine Patch 1.8% (ZTlido™) and Lidocaine Patch 5% (Lidoderm®) in Healthy Subjects Lidocaine topical system 1.8%, Lidocaine patch 5% - Healthy | Phase 1 | Completed | Scilex Pharmaceuticals, Inc. | 54 | 2016-09-28 | 2019-11-04 |
| Comparison of Prescription Lidocaine Patch to Over the Counter Lidocaine Patch and Placebo for Back Pain and Arthritis lidocaine 5% patch, lidocaine 3.6%, menthol 1.25%, Placebo - Back Pain, Arthritis | Not applicable | Unknown | J.A.R. Laboratories | 100 | 2016-04-01 | 2016-04-22 |
| Comparing Bupivacaine, Lidocaine, and a Combination of Bupivacaine and Lidocaine for Labor Epidural Activation 1% Lidocaine, 0.25% Bupivacaine, Bupivacaine plus Lidocaine - Labor Pain | Phase 3 | Completed | University of Alabama at Birmingham | 75 | 2015-10-08 | 2020-08-31 |
| Pharmacokinetic Study of Lidocaine Patch 1.8% Lidocaine Patch 5% (Lidoderm®) in Healthy Subjects Lidocaine patch 1.8%, Lidocaine 5% patch, Lidocaine 2% Injectable Solution - Healthy | Phase 1 | Completed | Scilex Pharmaceuticals, Inc. | 58 | 2014-04-28 | 2024-05-23 |
| Preventive Skin Analgesia With Lidocaine Patch 5% for Controlling Post-thoracotomy Pain Lidocaine patch 5%, Placebo patch - Pain, Postoperative | Not applicable | Completed | University of Campania Luigi Vanvitelli | 90 | 2013-01-01 | 2016-04-26 |
| Lidocaine 5% Patch (Lidoderm) for the Prevention of Acute and Chest Pain Following Robotic Valve Surgery Lidoderm 5 % Topical Patch, Placebo patch - Perioperative Chest Pain | Not applicable | Completed | The Cleveland Clinic | 80 | 2009-09-01 | 2020-04-17 |
| The Effect of Intravenous Lidocaine on Allodynia lidocaine - Pain | Not applicable | Completed | University of Alabama at Birmingham | 10 | 2008-12-01 | 2017-07-21 |
| Efficacy and Safety of the Lidoderm Patch Applied to Patients With Osteoarthritis of the Knee Lidoderm (Lidocaine 5% Patch), Placebo Patch - Osteoarthritis of the Knee | Phase 2 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 169 | 2007-03-01 | 2017-10-05 |
| Trial of Analgesia With Lidocaine or Extended-release Oxycodone for Neuropathic Pain Treatment in Multiple Sclerosis Lidocaine patch 5%, Extended-release oxycodone, Placebo extended-release oxycodone pills - Neuropathic Pain, Chronic Pain | Phase 4 | Terminated | University of Rochester | 19 | 2007-01-01 | 2015-07-17 |
| Safety and Efficacy of Lidoderm (Lidocaine Patch 5%) in Treating Moderate to Severe Pain Associated With Carpal Tunnel Syndrome lidocaine patch 5% - Carpal Tunnel Syndrome | Phase 3 | Terminated | Endo USA Inc., a Keenova Therapeutics Company | 210 | 2005-11-01 | 2011-06-14 |
| Pilot Study of Lidocaine 5% Patch Versus Placebo in Patients With Osteoarthritis Pain of the Knee Lidoderm, Placebo patch - Osteoarthritis, Knee | Phase 2 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 224 | 2004-08-01 | 2010-02-10 |
| A Study Comparing The Efficacy And Safety Of Lidocaine 5% Patch With Placebo In Patients With Chronic Axial Low Back Pain Lidoderm®, Placebo Topical Patch - Chronic Low Back Pain | Phase 2 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 215 | 2004-08-01 | 2013-12-06 |
| Lidocaine Patch 5% Versus Celecoxib 200 mg in Chronic Axial Low Back Pain Lidoderm®, Celecoxib - Chronic Low Back Pain | Phase 4 | Terminated | Endo USA Inc., a Keenova Therapeutics Company | 98 | 2004-07-01 | 2010-02-15 |
| Lidocaine Patch Versus Celecoxib in Pain From Osteoarthritis of the Knee Lidoderm, Celecoxib - Osteoarthritis of the Knee | Phase 4 | Terminated | Endo USA Inc., a Keenova Therapeutics Company | 2004-06-01 | 2010-02-15 | |
| Brain Imaging of Lidoderm for Chronic Back Pain lidocaine, placebo - Low Back Pain | Phase 4 | Completed | Northwestern University | 38 | 2004-01-01 | 2013-07-30 |
| Symptom Management After Breast Cancer Surgery Lidoderm patch, Placebo patch - Neuropathic Pain, Postmastectomy Pain | Phase 4 | Completed | University of California, San Francisco | 21 | 2003-09-01 | 2018-06-28 |
Showing 20 of 27. Sign in to see all of them.
Neuralgia, Postherpetic (4) · Osteoarthritis, Knee (3) · Carpal Tunnel Syndrome (2) · Complex Regional Pain Syndromes (2) · Diabetic Neuropathies (2) · Low Back Pain (2) · Neuralgia (2) · Pain (2) · Pain, Postoperative (2) · Arthritis (1) · Back Pain (1) · Breast Neoplasms (1) · Chronic Pain (1) · Diabetes Mellitus (1) · Herpes Zoster (1)
Endo USA Inc., a Keenova Therapeutics Company (11) · Scilex Pharmaceuticals, Inc. (3) · Grünenthal GmbH (2) · University of Alabama at Birmingham (2) · Hospital for Special Surgery, New York (1) · J.A.R. Laboratories (1) · Nicole K Brogden (1) · Northwestern University (1) · Oregon Health and Science University (1) · The Cleveland Clinic (1) · University of California, San Francisco (1) · University of Campania Luigi Vanvitelli (1) · University of Rochester (1)
United States (22)
Phillip LaStella, MD (3) · Apkar V. Apkarian, PhD (1) · Catherine Leclair, MD (1) · Ernest A. Kopecky, PhD, MBA (1) · Mario Santini, MD (1) · Mark F Powell, MD (1) · Michael Froelich, MD, MS (1) · Nicole K Brogden, PharmD, PhD (1) · Robert H. Dworkin, PhD (1) · Stavros Memtsoudis, MD/PhD (1)
PMID 32606914, PMID 18950528, PMID 19366301, PMID 19432499, PMID 22769236, PMID 33654425